-
1
-
-
0028180315
-
The TGF-β superfamily: New members, new receptors, and new genetic tests of function in different organisms
-
(1994)
Genes Dev.
, vol.8
, pp. 133-146
-
-
Kingsley, D.M.1
-
4
-
-
0030787152
-
Mechanism and function of signaling by the TGFβ superfamily
-
Protein Modeules in Signal Transduction, (Pawson A. J., Ed.) Springer-Verlag, Munchen
-
(1997)
, vol.228
, pp. 235-272
-
-
Hoodless, P.A.1
Wrana, J.L.2
-
13
-
-
0030058914
-
Caenorhabditis elegans genes sma2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 790-794
-
-
Savage, C.1
Das, P.2
Finelli, A.L.3
Townsend, S.R.4
Sun, C.-Y.5
Baird, S.E.6
Padget, R.W.7
-
19
-
-
0034614708
-
Structural basis of Smad2 recognition by the Smad anchor for receptor activation
-
(2000)
Science
, vol.287
, pp. 92-97
-
-
Wu, G.1
Chen, Y.-G.2
Ozdamar, B.3
Gyuricza, C.A.4
Chong, P.A.5
Wrana, J.L.6
Massague, J.7
Shi, Y.8
-
22
-
-
0034695590
-
The Smad4 Activation Domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2115-2122
-
-
De Caestecker, M.P.1
Yahata, T.2
Wang, D.3
Parks, W.T.4
Huang, S.5
Shioda, T.6
Roberts, A.B.7
Lechleider, R.J.8
-
30
-
-
0031587828
-
The MAD-related protein Smad7 Associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qui, Y.3
Cai, J.4
Xu, Y.-Y.5
Grinnell, B.W.6
Richardson, M.A.7
Topper, J.N.8
Gimbrone M.A., Jr.9
Wrana, J.L.10
Falb, D.11
-
32
-
-
0030611757
-
Identification of Smad7, a TGF-β inducible antagonist of TGF-β signalling
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Moren, A.3
Nakayama, T.4
Christian, J.L.5
Heuchel, R.6
Itoh, S.7
Kawabata, M.8
Heldin, N.-E.9
Heldin, C.-H.10
Ten Dijke, P.11
-
44
-
-
0039844411
-
Interaction and functional cooperation of PEBP2/CBF with Smads
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31577-31582
-
-
Hanai, J.-I.1
Chen, L.F.2
Kanno, T.3
Ohtani-Fujito, N.4
Kim, W.Y.5
Guo, W.-H.6
Imamura, T.7
Ishidou, Y.8
Fukuchi, M.9
Shi, M.-J.10
Stavnezer, J.11
Kawabata, M.12
Miyazono, K.13
Ito, Y.14
-
46
-
-
0033575194
-
SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20489-20498
-
-
Verschueren, K.1
Remacle, J.E.2
Collart, C.3
Kraft, H.4
Baker, B.S.5
Tylzanowski, P.6
Nelles, L.7
Wuytens, G.8
Su, M.-T.9
Bodmer, R.10
Smith, J.C.11
Huylebroeck, D.12
-
55
-
-
0032544076
-
Transcriptional activating activity of Smad4: Roles of SMAD heterooligomerization and enhancement by an associating transactivator
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9785-9790
-
-
Shioda, T.1
Lechleider, R.J.2
Dunwoodie, S.L.3
Li, H.4
Yahata, T.5
De Caestecker, M.P.6
Fenner, M.H.7
Roberts, A.B.8
Isselbacher, K.J.9
-
58
-
-
0032474868
-
The oncoprotein Evi-1 represses TGF-β signalling by inhibiting Smad3
-
(1998)
Nature
, vol.394
, pp. 92-96
-
-
Kurokawa, M.1
Mitani, K.2
Irie, K.3
Matsuyama, T.4
Takahashi, T.5
Chiba, S.6
Yazaki, Y.7
Matsumoto, K.8
Hirai, H.9
-
60
-
-
16044369574
-
MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
-
(1996)
Cell
, vol.86
, pp. 543-552
-
-
Eppert, K.1
Scherer, S.W.2
Ozcelik, H.3
Pirone, R.4
Hoodless, P.5
Kim, H.6
Tsui, L.-Ch.7
Bapat, B.8
Gallinger, S.9
Andrulis, I.L.10
Thomsen, G.H.11
Wrana, J.L.12
Attisano, L.13
-
61
-
-
0030593038
-
DPC4, a candidate tumor supressor gene at human chromosome 18q21.1
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Mosaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fisher, A.8
Yeo, C.J.9
Hurban, R.H.10
Kern, S.E.11
-
62
-
-
15844387270
-
Mad-related genes in human
-
(1996)
Nature Genet.
, vol.13
, pp. 347-349
-
-
Riggins, G.J.1
Thiagalingam, S.2
Rozenblum, E.3
Weinstein, C.L.4
Kern, S.E.5
Hamilton, S.R.6
Wilson, J.V.K.7
Markowitz, S.D.8
Kinzler, K.W.9
Vogelstein, B.10
-
65
-
-
0032775701
-
Screening SMAD1, SMAD2, SMAD3, and SMAD5 for germline mutations in juvenile polyposis syndrome
-
(1999)
Gut
, vol.45
, pp. 406-408
-
-
Bevan, S.1
Woodford-Richens, K.2
Rozen, P.3
Eng, C.4
Young, J.5
Dunlop, M.6
Neale, K.7
Phillips, R.8
Markie, D.9
Rodriguez-Bigas, M.10
Leggett, B.11
Sheridan, E.12
Hodgson, S.13
Iwama, T.14
Eccles, D.15
Bodmer, W.16
Houlston, R.17
Tomlinson, I.18
-
66
-
-
0031034589
-
Identification of Smad2, a human Mad-related protein in the transforming growth factor β signaling pathway
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2896-2900
-
-
Nakao, A.1
Roijer, E.2
Imamura, T.3
Souchelnytskyi, S.4
Stenman, G.5
Heldin, C.-H.6
Ten Dijke, P.7
-
67
-
-
0031889595
-
Characterization of the MADH2/Smad2 gene, a human Mad homolog responsible for the Transforming growth factor-β and Activin signal transduction pathway
-
(1998)
Genomics
, vol.48
, pp. 1-11
-
-
Takenoshita, S.1
Mogi, A.2
Nagashima, M.3
Yang, K.4
Yagi, K.5
Hanyu, A.6
Nagamachi, Y.7
Myizono, K.8
Hagiwara, K.9
-
68
-
-
0031756444
-
Somatic alterations of the SMAD-2 gene in human colorectal cancers
-
(1998)
Br. J. Cancer
, vol.78
, pp. 1152-1155
-
-
Takagi, Y.1
Koumura, H.2
Futamura, M.3
Aoki, S.4
Ymaguchi, K.5
Kida, H.6
Tanemura, H.7
Shimokawa, K.8
Saji, S.9
-
69
-
-
0029731630
-
Somatic in vivo alterations of the JV18-1 gene at 18q21 in human lung cancers
-
(1996)
Cancer Res.
, vol.56
, pp. 5583-5585
-
-
Uchida, K.1
Nagatake, M.2
Osada, H.3
Yatabe, Y.4
Kondo, M.5
Mitsudomi, T.6
Masuda, A.7
Takahashi, T.8
Takahashi, T.9
-
73
-
-
0032889954
-
Molecular analyses of the 15q and 18q SMAD genes in pancreatic cancer
-
(1999)
Genes Chromosom. Cancer
, vol.24
, pp. 62-71
-
-
Jonson, T.1
Gorunova, L.2
Dawiskiba, S.3
Andren-Sandberg, A.4
Stenman, G.5
Ten Dijke, P.6
Johansson, B.7
Hoglund, M.8
-
74
-
-
9344223357
-
DPC4 gene in various tumor types
-
(1996)
Cancer Res.
, vol.56
, pp. 2527-2530
-
-
Schutte, M.1
Hurban, R.H.2
Hedrick, L.3
Cho, K.R.4
Nadasady, G.M.5
Weinstein, C.L.6
Bova, G.S.7
Isaacs, W.B.8
Cairns, P.9
Nawroz, H.10
Sidransky, D.11
Casero R.A., Jr.12
Meltzer, P.S.13
Hahn, S.A.14
Kern, S.E.15
-
75
-
-
0032936925
-
Involvement of mutations in the DPC4 promoter in endometrial carcinoma development
-
(1999)
Mol. Carcinogen.
, vol.25
, pp. 64-72
-
-
Zhou, Y.1
Kato, H.2
Shan, D.3
Minami, R.4
Kitazawa, S.5
Matsuda, T.6
Arima, T.7
Barrett, J.C.8
Wake, N.9
-
77
-
-
0029933642
-
Somatic in vivo alterations of the DPC4 gene at 18q21 in human lung cancers
-
(1996)
Cancer Res.
, vol.56
, pp. 2718-2720
-
-
Nagatake, M.1
Takagi, Y.2
Osada, H.3
Uchida, K.4
Mitsudomi, T.5
Saji, S.6
Shimatokata, K.7
Takahashi, T.8
Takahasi, T.9
-
78
-
-
0000799313
-
DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma
-
(1996)
Cancer Res.
, vol.56
, pp. 2519-2521
-
-
Kim, S.K.1
Fan, Y.2
Papadimitrakopoulou, V.3
Clayman, G.4
Hittelman, W.N.5
Hong, W.K.6
Lotan, R.7
Mao, L.8
-
79
-
-
8044247811
-
Infrequent DPC4 gene mutation in esophageal cancer, gastric cancer and ulcerative colitis-associated neoplasms
-
(1996)
Oncogene
, vol.13
, pp. 2459-2462
-
-
Lei, J.1
Zou, T.T.2
Shi, Y.O.3
-
82
-
-
0033587156
-
Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis
-
(1999)
Oncogene
, vol.18
, pp. 3098-3103
-
-
Miyaki, M.1
Iijima, T.2
Konishi, M.3
Sakai, K.4
Ishii, A.5
Yasuno, M.6
Hishima, T.7
Koike, M.8
Shitara, N.9
Iwama, T.10
Utsunomiya, J.11
Kuroki, T.12
Mori, T.13
-
84
-
-
0032865413
-
SMAD genes in juvenile polyposis
-
(1999)
Genes Chromosom. Cancer
, vol.26
, pp. 54-61
-
-
Roth, S.1
Sistonen, P.2
Salovaara, R.3
Hemminki, A.4
Loukola, A.5
Johansson, M.6
Avizienyte, E.7
Cleary, K.A.8
Lynch, P.9
Amos, C.I.10
Kristo, P.11
Mecklin, J.-P.12
Kellokumpu, I.13
Jarvinen, H.14
Aaltonen, L.A.15
|