Intracellular signaling: Fleshing out the TGFβ pathway

Current Biology

Volumn 9, Issue 11, 1999, Pages

  Padgett, Richard W ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0033519679     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(99)80255-3     Document Type: Note

References (14)

1. Heldin CH, Miyazono K, ten Dijke P: TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 1997, 390:465-471.
2. Massagué J: TGFβ signal transduction. Annu Rev Biochem 1998, 67:753-791.
3. Padgett RW, Das P, Krishna S: TGFβ signaling, smads, and tumor suppressors. Bioessays 1998, 20:382-390.
4. Huse M, Chen YG, Massague J, Kuriyan J: Crystal structure of the cytoplasmic domain of the type l TGFβ receptor in complex with FKBP12. Cell 1999, 96:425-436.
5. Tsukazaki T, Chiang TA, Davison AF, Attisano L, Wrana JL: SARA, a FYVE domain protein that recruits Smad2 to the TGFβ receptor. Cell 1998, 95:779-791.
6. Krishna S, Maduzia LL, Padgett RW: Specificity of tgfβ signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans. Development 1999, 126:251-260.
7. Feng XH, Filvaroff EH, Derynck R: Transforming growth factor-β (TGF-β) induced down-regulation of cyclin A expression requires a functional TGF-β receptor complex. Characterization of chimeric and truncated type I ánd type II receptors. J Biol Chem 1995, 270:24237-24245.
8. Savage C, Das P, Finelli AL, Townsend SR, Sun CY, Baird SE, Padgett RW: Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor β pathway components. Proc Natl Acad Sci USA 1996, 93:790-794.
9. Das P, Inoue H, Baker JC, Beppu H, Kawabata M, Harland RM, Miyazono K, Padgett RW: Drosophila dSmad2 and Atr-l transmit activin/TGFβ signals. Genes Cells 1999, 4:123-134.
10. Brummel T, Abdollah S, Haerry TE, Shimell MJ, Merriam J, Raftery L, Wrana JL, O'Connor MB: The Drosophila activin receptor baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development. Genes Dev 1999, 13:98-111.
11. Kretzschmar M, Doody J, Massagué J: Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1. Nature 1997, 389:618-622.
12. de Caestecker MP, Parks WT, Frank CJ, Castagnino P, Bottaro DP, Roberts AB, Lechleider RJ: Smad2 transduces common signals from receptor serine threonine and tyrosine kinases. Genes Dev 1998, 12:1587-1592.
13. Ulloa L, Doody J, Massague J: Inhibition of transforming growth factor β/SMAD signalling by the interferon-γ/STAT pathway. Nature 1999, 397:710-713.
14. Yanagisawa J, Yanagi Y, Masuhiro Y, Suzawa M, Watanabe M, Kashiwagi K, Toriyabe T, Kawabata M, Miyazono K, Kato S: Convergence of transforming growth factor-β and vitamin D signaling pathways on SMAD transcriptional coactivators. Science 1999, 283:1317-1321.