메뉴 건너뛰기




Volumn 58, Issue 20, 1998, Pages 4592-4597

Dpc4 transcriptional activation and dysfunction in cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MESSENGER RNA; PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 0000128027     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (85)

References (34)
  • 6
    • 0028940853 scopus 로고
    • Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster
    • Sekelsky, J. J., Newfeld, S. J., Raftery, L. A., Chartoff, E. H., and Gelbart, W. M. Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics, 139: 1347-1358, 1995.
    • (1995) Genetics , vol.139 , pp. 1347-1358
    • Sekelsky, J.J.1    Newfeld, S.J.2    Raftery, L.A.3    Chartoff, E.H.4    Gelbart, W.M.5
  • 8
    • 0030058914 scopus 로고    scopus 로고
    • Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor β pathway components
    • Savage, C., Das, P., Finelli, A. L., Townsend, S. R., Sun, C-Y., Baird, S. E., and Padgett, R. W. Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor β pathway components. Proc. Natl. Acad. Sci. USA, 93: 790-794, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 790-794
    • Savage, C.1    Das, P.2    Finelli, A.L.3    Townsend, S.R.4    Sun, C.-Y.5    Baird, S.E.6    Padgett, R.W.7
  • 11
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type I gene
    • Dennler, S., Itoh, S., Vivien, D., ten Dijke, P., Huet, S., and Gauthier, J-M. Direct binding of Smad3 and Smad4 to critical TGF-β-inducible elements in the promoter of human plasminogen activator inhibitor-type I gene. EMBO J., 17: 3091-3100, 1998.
    • (1998) EMBO J. , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    Ten Dijke, P.4    Huet, S.5    Gauthier, J.-M.6
  • 12
    • 0029834067 scopus 로고    scopus 로고
    • Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways
    • Lagna, G., Hata, A., Hemmati-Brivanlou, A., and Massagué, J. Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways. Nature (Lond.), 383: 832-836, 1996.
    • (1996) Nature (Lond.) , vol.383 , pp. 832-836
    • Lagna, G.1    Hata, A.2    Hemmati-Brivanlou, A.3    Massagué, J.4
  • 13
    • 0029786212 scopus 로고    scopus 로고
    • Receptor-associated Mad homologues synergize as effectors of the TGF-β response
    • Zhang, Y., Feng, X., We, R., and Derynck, R. Receptor-associated Mad homologues synergize as effectors of the TGF-β response. Nature (Lond.), 383: 168-172, 1996.
    • (1996) Nature (Lond.) , vol.383 , pp. 168-172
    • Zhang, Y.1    Feng, X.2    We, R.3    Derynck, R.4
  • 15
    • 0031128153 scopus 로고    scopus 로고
    • The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function
    • Zhang, Y., Musci, T., and Derynck, R. The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function. Curr. Biol., 7: 270-276, 1997.
    • (1997) Curr. Biol. , vol.7 , pp. 270-276
    • Zhang, Y.1    Musci, T.2    Derynck, R.3
  • 16
    • 0029810920 scopus 로고    scopus 로고
    • Attenuated ALK5 receptor expression in human pancreatic cancer: Correlation with resistance to growth inhibition
    • Baldwin, R. L., Friess, H., Yokoyama, M., Lopez, M. E., Kobrin, M. S., Buchler, M. W., and Korc, M. Attenuated ALK5 receptor expression in human pancreatic cancer: correlation with resistance to growth inhibition. Int. J. Cancer, 67: 283-288, 1996.
    • (1996) Int. J. Cancer , vol.67 , pp. 283-288
    • Baldwin, R.L.1    Friess, H.2    Yokoyama, M.3    Lopez, M.E.4    Kobrin, M.S.5    Buchler, M.W.6    Korc, M.7
  • 17
    • 0030612484 scopus 로고    scopus 로고
    • WAF1 expression and growth inhibition by transforming growth factor β involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells
    • WAF1 expression and growth inhibition by transforming growth factor β involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells. Cancer Res., 57: 3929-3934, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 3929-3934
    • Grau, A.M.1    Zhang, L.2    Wang, W.3    Ruan, S.4    Evans, D.B.5    Abbruzzese, J.L.6    Zhang, W.7    Chiao, P.J.8
  • 18
    • 0030690337 scopus 로고    scopus 로고
    • Dual role of the Smad4/DPC4 tumor suppressor in TGF-β-inducible transcriptional complexes
    • Liu, F., Pouponnot, C., and Massagué, J. Dual role of the Smad4/DPC4 tumor suppressor in TGF-β-inducible transcriptional complexes. Genes Dev., 11: 3157-3167, 1997.
    • (1997) Genes Dev. , vol.11 , pp. 3157-3167
    • Liu, F.1    Pouponnot, C.2    Massagué, J.3
  • 19
  • 20
    • 0000799313 scopus 로고    scopus 로고
    • DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma
    • Kim, S. K., Fan, Y., Papadimitrakopoulou, V., Clayman, G., Hittleman, W. N., Hong, W. K., Lotan, R., and Mao, L. DPC4, a candidate tumor suppressor gene, is altered infrequently in head and neck squamous cell carcinoma. Cancer Res., 56: 2519-2521, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 2519-2521
    • Kim, S.K.1    Fan, Y.2    Papadimitrakopoulou, V.3    Clayman, G.4    Hittleman, W.N.5    Hong, W.K.6    Lotan, R.7    Mao, L.8
  • 22
    • 0030825516 scopus 로고    scopus 로고
    • Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4
    • Hata, A., Lo, R. S., Wotton, D., Lagna, G., and Massagué, J. Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4. Nature (Lond.), 388: 82-87, 1997.
    • (1997) Nature (Lond.) , vol.388 , pp. 82-87
    • Hata, A.1    Lo, R.S.2    Wotton, D.3    Lagna, G.4    Massagué, J.5
  • 23
    • 0029002136 scopus 로고
    • A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins
    • Littlewood, T. D., Hancock, D. C., Danielian, P. S., Parker, M. G., and Evan, G. I. A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res., 23: 1686-1690, 1995.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1686-1690
    • Littlewood, T.D.1    Hancock, D.C.2    Danielian, P.S.3    Parker, M.G.4    Evan, G.I.5
  • 24
  • 25
    • 0030872367 scopus 로고    scopus 로고
    • Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic
    • Kim, J., Johnson, K., Chen, H. J., Carroll, S., and Laughon, A. Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature (Lond.), 388: 304-308, 1997.
    • (1997) Nature (Lond.) , vol.388 , pp. 304-308
    • Kim, J.1    Johnson, K.2    Chen, H.J.3    Carroll, S.4    Laughon, A.5
  • 26
    • 0026448672 scopus 로고
    • Regulation of the specific DNA binding function of p53
    • Hupp, T. R., Meek, D. W., Midgley, C. A., and Lane, D. P. Regulation of the specific DNA binding function of p53. Cell, 71: 875-886, 1992.
    • (1992) Cell , vol.71 , pp. 875-886
    • Hupp, T.R.1    Meek, D.W.2    Midgley, C.A.3    Lane, D.P.4
  • 27
    • 0030300115 scopus 로고    scopus 로고
    • MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling
    • Macias-Silva, M., Abdollah, S., Hoodless, P. A., Pirone, R., Attisano, L., and Wrana, J. L. MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling. Cell, 87: 1215-1224, 1996.
    • (1996) Cell , vol.87 , pp. 1215-1224
    • Macias-Silva, M.1    Abdollah, S.2    Hoodless, P.A.3    Pirone, R.4    Attisano, L.5    Wrana, J.L.6
  • 28
    • 0031812292 scopus 로고    scopus 로고
    • The Drosophila gene Medea demonstrates the requirement for different classes of Smads in dpp signaling
    • Camb.
    • Das, P., Maduzia, L. L., Wang, H., Finelli, A. L., Cho, S-H., Smith, M. M., and Padgett, R. W. The Drosophila gene Medea demonstrates the requirement for different classes of Smads in dpp signaling. Development (Camb.), 125: 1519-1528, 1998.
    • (1998) Development , vol.125 , pp. 1519-1528
    • Das, P.1    Maduzia, L.L.2    Wang, H.3    Finelli, A.L.4    Cho, S.-H.5    Smith, M.M.6    Padgett, R.W.7
  • 30
    • 0030837455 scopus 로고    scopus 로고
    • A structural basis for mutational inactivation of the tumour suppressor Smad4
    • Shi, Y., Hata, A., Lo, R. S., Massagué, J., and Pavletich, N. P. A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature (Lond.), 388: 87-93, 1997.
    • (1997) Nature (Lond.) , vol.388 , pp. 87-93
    • Shi, Y.1    Hata, A.2    Lo, R.S.3    Massagué, J.4    Pavletich, N.P.5
  • 33
    • 0029022221 scopus 로고
    • GS domain mutations that constitutively activate TGFβ R-I, the downstream signaling component in the TGF-β receptor complex
    • Wieser, R., Wrana, J. L., and Massagué, J. GS domain mutations that constitutively activate TGFβ R-I, the downstream signaling component in the TGF-β receptor complex. EMBO J., 14: 2199-2208, 1995.
    • (1995) EMBO J. , vol.14 , pp. 2199-2208
    • Wieser, R.1    Wrana, J.L.2    Massagué, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.