-
1
-
-
0001010670
-
Signal transduction from membrane to cytoplasm: Growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity
-
Morrison, D. K., D. R. Kaplan, U. Rapp, and T. M. Roberts. Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity. Proc. Natl. Acad. Sci. USA 85:8855-8859 (1988).
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 8855-8859
-
-
Morrison, D.K.1
Kaplan, D.R.2
Rapp, U.3
Roberts, T.M.4
-
2
-
-
0026011855
-
Interleukin 2 induces tyrosine phosphorylation and activation of p72-74 Raf-1 kinase in a T-cell line
-
Turner, B., U. Rapp, H. App, M. Greene, K. Dobashi, and J. Reed. Interleukin 2 induces tyrosine phosphorylation and activation of p72-74 Raf-1 kinase in a T-cell line. Proc. Natl. Acad. Sci. USA 88:1227-1231 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 1227-1231
-
-
Turner, B.1
Rapp, U.2
App, H.3
Greene, M.4
Dobashi, K.5
Reed, J.6
-
3
-
-
0028272507
-
Requirement for ras in raf activation is overcome by targeting raf to the plasma membrane
-
Leevers, S. J., H. F. Paterson, and C. J. Marshall. Requirement for ras in raf activation is overcome by targeting raf to the plasma membrane. Nature (Lond.) 369:411-414 (1994).
-
(1994)
Nature (Lond.)
, vol.369
, pp. 411-414
-
-
Leevers, S.J.1
Paterson, H.F.2
Marshall, C.J.3
-
4
-
-
0028241533
-
Activation of Raf as a result of recruitment to the plasma membrane
-
Stokoe, D., S. G. Macdonald, K. Cadwallader, M. Symons, and J. F. Hancock. Activation of Raf as a result of recruitment to the plasma membrane. Science (Washington D. C.) 264:1463-1466 (1994).
-
(1994)
Science (Washington D. C.)
, vol.264
, pp. 1463-1466
-
-
Stokoe, D.1
Macdonald, S.G.2
Cadwallader, K.3
Symons, M.4
Hancock, J.F.5
-
5
-
-
0027326410
-
Protein kinase Cα activates RAF-1 by direct phosphorylation
-
Kolch, W., G. Heidecker, G. Kochs, R. Hummel, H. Vahidi, H. Mischak, G. Finkenzeller, D. Marme, and U. R. Rapp. Protein kinase Cα activates RAF-1 by direct phosphorylation. Nature (Lond.) 364:249-252 (1993).
-
(1993)
Nature (Lond.)
, vol.364
, pp. 249-252
-
-
Kolch, W.1
Heidecker, G.2
Kochs, G.3
Hummel, R.4
Vahidi, H.5
Mischak, H.6
Finkenzeller, G.7
Marme, D.8
Rapp, U.R.9
-
6
-
-
0029006126
-
Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation
-
Marais, R., Y. Light, H. F. Paterson, and C. J. Marshall. Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation. EMBO J. 14:3136-3145 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 3136-3145
-
-
Marais, R.1
Light, Y.2
Paterson, H.F.3
Marshall, C.J.4
-
7
-
-
0027165150
-
The mitogen-activated protein kinase signal transduction pathway
-
Davis, R. J. The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 268:14553-14556 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 14553-14556
-
-
Davis, R.J.1
-
8
-
-
0028104204
-
The ins and outs of Raf kinases
-
Daum, G., I. Eisenmann-Tappe, H.-W. Fries, J. Troppmair, and U. R. Rapp. The ins and outs of Raf kinases. Trends Biol. Sci. 19:474-480 (1994).
-
(1994)
Trends Biol. Sci.
, vol.19
, pp. 474-480
-
-
Daum, G.1
Eisenmann-Tappe, I.2
Fries, H.-W.3
Troppmair, J.4
Rapp, U.R.5
-
9
-
-
0028175091
-
Raf meets Ras: Completing the framework of a signal transduction pathway
-
Avruch, J., X.-F. Zhang, and J. M. Kyriakis. Raf meets Ras: completing the framework of a signal transduction pathway. Trends Biol. Sci. 19:279-283 (1994).
-
(1994)
Trends Biol. Sci.
, vol.19
, pp. 279-283
-
-
Avruch, J.1
Zhang, X.-F.2
Kyriakis, J.M.3
-
10
-
-
0025266334
-
Expression of raf family proto-oncogenes in normal mouse tissues
-
Storm, S. M., J. L. Cleveland, and U. R. Rapp. Expression of raf family proto-oncogenes in normal mouse tissues. Oncogene 5:345-351 (1990).
-
(1990)
Oncogene
, vol.5
, pp. 345-351
-
-
Storm, S.M.1
Cleveland, J.L.2
Rapp, U.R.3
-
11
-
-
0028270718
-
Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires raf and is necessary for transformation
-
Troppmair, J., J. T. Bruder, H. Munoz, P. A. Lloyd, J. Kyriakis, P. Banerjee, J. Avruch, and U. R. Rapp. Mitogen-activated protein kinase/extracellular signal-regulated protein kinase activation by oncogenes, serum, and 12-O-tetradecanoylphorbol-13-acetate requires raf and is necessary for transformation. J. Biol. Chem. 269:7030-7035 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 7030-7035
-
-
Troppmair, J.1
Bruder, J.T.2
Munoz, H.3
Lloyd, P.A.4
Kyriakis, J.5
Banerjee, P.6
Avruch, J.7
Rapp, U.R.8
-
12
-
-
0026744028
-
Raf-1 protein kinase is an integral component of the oncogenic signal cascade shared by epidermal growth factor and platelet-derived growth factor
-
Kizaka-Kondoh, S., K. Sato, K. Tamura, H. Nojima, and H. Okayama. Raf-1 protein kinase is an integral component of the oncogenic signal cascade shared by epidermal growth factor and platelet-derived growth factor. Mol. Cell. Biol. 12:5078-5086 (1992).
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5078-5086
-
-
Kizaka-Kondoh, S.1
Sato, K.2
Tamura, K.3
Nojima, H.4
Okayama, H.5
-
13
-
-
0027317736
-
An inhibitory raf-1 mutant suppresses expression of a subset of v-raf-activated genes
-
Miltenberger, R. J., J. Cortnet, and P. J. Farnham. An inhibitory raf-1 mutant suppresses expression of a subset of v-raf-activated genes. J. Biol. Chem. 268:15674-15680 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15674-15680
-
-
Miltenberger, R.J.1
Cortnet, J.2
Farnham, P.J.3
-
14
-
-
0025979335
-
Raf-1 protein kinase is required for growth of induced NIH/3T3 cells
-
Kolch, W., G. Heidecker, P. Lloyd, and U. R. Rapp. Raf-1 protein kinase is required for growth of induced NIH/3T3 cells. Nature (Lond.) 349:426-428 (1991).
-
(1991)
Nature (Lond.)
, vol.349
, pp. 426-428
-
-
Kolch, W.1
Heidecker, G.2
Lloyd, P.3
Rapp, U.R.4
-
15
-
-
0029977448
-
Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
-
Monia, B. P., J. F. Johnston, T. Geiger, M. Muller, and D. Fabbro. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nature Med. 2:668-675 (1996).
-
(1996)
Nature Med.
, vol.2
, pp. 668-675
-
-
Monia, B.P.1
Johnston, J.F.2
Geiger, T.3
Muller, M.4
Fabbro, D.5
-
16
-
-
0028111836
-
B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP
-
Vaillancourt, R. R., A. M. Gardner, and G. L. Johnson. B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP. Mol. Cell. Biol. 14:6522-6530 (1994).
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 6522-6530
-
-
Vaillancourt, R.R.1
Gardner, A.M.2
Johnson, G.L.3
-
17
-
-
0028839220
-
Hypertrophic agonists stimulate the activities of the protein kinases c-Raf and A-Raf in cultured ventricular myocytes
-
Bogoyevitch, M. A., C. J. Marshall, and P. H. Sugden. Hypertrophic agonists stimulate the activities of the protein kinases c-Raf and A-Raf in cultured ventricular myocytes. J. Biol. Chem. 270:26303-26310 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26303-26310
-
-
Bogoyevitch, M.A.1
Marshall, C.J.2
Sugden, P.H.3
-
18
-
-
0028965111
-
Biochemical analysis of MEK activation in NIH3T3 fibroblasts. Identification of B-Raf and other activators
-
Reuter, C. W. M., A. D. Catling, T. Jelinek, and M. J. Weber. Biochemical analysis of MEK activation in NIH3T3 fibroblasts. Identification of B-Raf and other activators. J. Biol. Chem. 270:7644-7655 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7644-7655
-
-
Reuter, C.W.M.1
Catling, A.D.2
Jelinek, T.3
Weber, M.J.4
-
19
-
-
0030062094
-
Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells
-
Wu, X., S. J. Noh, G. Zhou, J. E. Dixon, and K.-L. Guan. Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells. J. Biol. Chem. 271:3265-3271 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3265-3271
-
-
Wu, X.1
Noh, S.J.2
Zhou, G.3
Dixon, J.E.4
Guan, K.-L.5
-
21
-
-
0027293123
-
Downregulation of c-myc expression by antisense oligonucleotides inhibits proliferation of human smooth muscle cells
-
Shi, Y., H. G. Hutchinson, D. J. Hall, and A. Zalewski. Downregulation of c-myc expression by antisense oligonucleotides inhibits proliferation of human smooth muscle cells. Circulation 88:1190-1195 (1993).
-
(1993)
Circulation
, vol.88
, pp. 1190-1195
-
-
Shi, Y.1
Hutchinson, H.G.2
Hall, D.J.3
Zalewski, A.4
-
22
-
-
0026773852
-
Inhibition of smooth muscle cell proliferation by an antisense oligodeoxynucleotide targeting the messenger RNA encoding proliferating cell nuclear antigen
-
Speir, E., and S. E. Epstein. Inhibition of smooth muscle cell proliferation by an antisense oligodeoxynucleotide targeting the messenger RNA encoding proliferating cell nuclear antigen. Circulation 86:538-547 (1992).
-
(1992)
Circulation
, vol.86
, pp. 538-547
-
-
Speir, E.1
Epstein, S.E.2
-
23
-
-
0028946244
-
Growth-related responses in arterial smooth muscle cells are arrested by thrombin receptor antisense sequences
-
Chaikof, E. L., R. Caban, C.-N. Yan, G. N. Rao, and M. S. Runge. Growth-related responses in arterial smooth muscle cells are arrested by thrombin receptor antisense sequences. J. Biol. Chem. 270:7431-7436 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7431-7436
-
-
Chaikof, E.L.1
Caban, R.2
Yan, C.-N.3
Rao, G.N.4
Runge, M.S.5
-
24
-
-
0029057798
-
Regulation of vascular smooth muscle cell insulin-like growth factor 1 receptors by phosphorothioate oligonucleotides. Effects on cell growth and evidence that sense targeting at the ATG site increases receptor expression
-
Delafontaine, P., X. P. Meng, L. Ku, and J. Du. Regulation of vascular smooth muscle cell insulin-like growth factor 1 receptors by phosphorothioate oligonucleotides. Effects on cell growth and evidence that sense targeting at the ATG site increases receptor expression. J. Biol. Chem. 270:14383-14388 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14383-14388
-
-
Delafontaine, P.1
Meng, X.P.2
Ku, L.3
Du, J.4
-
25
-
-
0028246149
-
Antisense proliferating cell nuclear antigen oligonucleotides inhibit intimai hyperplasia in a rat carotid artery injury model
-
Simons, M., E. R. Edelman, and R. D. Rosenberg. Antisense proliferating cell nuclear antigen oligonucleotides inhibit intimai hyperplasia in a rat carotid artery injury model. J. Clin. Invest. 93:2351-2356 (1994).
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 2351-2356
-
-
Simons, M.1
Edelman, E.R.2
Rosenberg, R.D.3
-
26
-
-
0028908962
-
c-myc in vasculoproliferative disease
-
Edelman, E. R., M. Simons, M. G. Sirois, and R. D. Rosenberg. c-myc in vasculoproliferative disease. Circ. Res. 76:176-182 (1995).
-
(1995)
Circ. Res.
, vol.76
, pp. 176-182
-
-
Edelman, E.R.1
Simons, M.2
Sirois, M.G.3
Rosenberg, R.D.4
-
27
-
-
0027168725
-
Evaluation of 2′ modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression
-
Monia, B. P., E. A. Lesnik, C. Gonzalez, W. F. Lima, D. McGee, C. J. Guinesse, A. M. Kawasaki, P. D. Cook, and S. M. Freier. Evaluation of 2′ modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression. J. Biol. Chem. 268:14514-14522 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 14514-14522
-
-
Monia, B.P.1
Lesnik, E.A.2
Gonzalez, C.3
Lima, W.F.4
McGee, D.5
Guinesse, C.J.6
Kawasaki, A.M.7
Cook, P.D.8
Freier, S.M.9
-
28
-
-
0024804759
-
Absorbance melting curves of RNA
-
Puglisi, J. D., and I. Tinoco. Absorbance melting curves of RNA. Methods Enzymol. 180:304-325 (1989).
-
(1989)
Methods Enzymol.
, vol.180
, pp. 304-325
-
-
Puglisi, J.D.1
Tinoco, I.2
-
29
-
-
0020674698
-
Base-stacking and base pairing contributions to helix stability: Thermodynamics of double-helix formation with CCGG, CCGGp, CCGGAp, ACCGGp, CCGGUp, and ACCGGUp
-
Petersheim, M., and D. H. Turner. Base-stacking and base pairing contributions to helix stability: thermodynamics of double-helix formation with CCGG, CCGGp, CCGGAp, ACCGGp, CCGGUp, and ACCGGUp. Biochemistry 22:256-263 (1983).
-
(1983)
Biochemistry
, vol.22
, pp. 256-263
-
-
Petersheim, M.1
Turner, D.H.2
-
30
-
-
0028062847
-
Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides
-
Dean, N. M., and R. McKay. Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides. Proc. Natl. Acad. Sci USA 91:11762-11766 (1994).
-
(1994)
Proc. Natl. Acad. Sci USA
, vol.91
, pp. 11762-11766
-
-
Dean, N.M.1
McKay, R.2
-
31
-
-
0027092897
-
Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides
-
Bennett, C. F., M.-Y. Chiang, H. Chan, J. E. E. Shoemaker, and C. K. Mirabelli. Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides. Mol. Pharmacol. 41:1023-1033 (1992).
-
(1992)
Mol. Pharmacol.
, vol.41
, pp. 1023-1033
-
-
Bennett, C.F.1
Chiang, M.-Y.2
Chan, H.3
Shoemaker, J.E.E.4
Mirabelli, C.K.5
-
32
-
-
0026737456
-
Anti-sense oligodeoxynucleotides - Promises and pitfalls
-
Stein, C. A. Anti-sense oligodeoxynucleotides - promises and pitfalls. Leukemia 6:967-974 (1992).
-
(1992)
Leukemia
, vol.6
, pp. 967-974
-
-
Stein, C.A.1
-
33
-
-
0028806487
-
Does antisense exist? It may, but only under very special circumstances
-
Stein, C. A. Does antisense exist? It may, but only under very special circumstances. Nature Med. 1:1119-1121 (1995).
-
(1995)
Nature Med.
, vol.1
, pp. 1119-1121
-
-
Stein, C.A.1
-
34
-
-
0028019410
-
Gene inhibition using antisense oligodeoxynucleotides
-
Wagner, R. W. Gene inhibition using antisense oligodeoxynucleotides. Nature (Lond.) 372:333-335, 1994.
-
(1994)
Nature (Lond.)
, vol.372
, pp. 333-335
-
-
Wagner, R.W.1
-
35
-
-
0023650861
-
Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H
-
Inoue, H., Y. Hayase, S. Iwai, and E. Ohtsuka. Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H. FEBS Lett. 215:327-330 (1987).
-
(1987)
FEBS Lett.
, vol.215
, pp. 327-330
-
-
Inoue, H.1
Hayase, Y.2
Iwai, S.3
Ohtsuka, E.4
-
36
-
-
0027250250
-
Mammalian ras interacts directly with the serine/threonine kinase raf
-
Vojtek, A. B., S. M. Hollenbuerg, and J. A. Cooper. Mammalian ras interacts directly with the serine/threonine kinase raf. Cell 74:205-214 (1993).
-
(1993)
Cell
, vol.74
, pp. 205-214
-
-
Vojtek, A.B.1
Hollenbuerg, S.M.2
Cooper, J.A.3
-
37
-
-
0029919472
-
Posttranslational modification of H-Ras is required for activation of, but not for association with, B-Raf
-
Okada, T., T. Masuda, M. Shinkai, K. Kariya, and T. Kataoka. Posttranslational modification of H-Ras is required for activation of, but not for association with, B-Raf. J. Biol. Chem. 271:4671-4678 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4671-4678
-
-
Okada, T.1
Masuda, T.2
Shinkai, M.3
Kariya, K.4
Kataoka, T.5
-
38
-
-
0027932734
-
Ras proteins regulate multiple mitogenic pathways in A10 vascular smooth muscle cells
-
Irani, K., S. Herzlinger, and T. Finkel. Ras proteins regulate multiple mitogenic pathways in A10 vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 202:1252-1258 (1994).
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.202
, pp. 1252-1258
-
-
Irani, K.1
Herzlinger, S.2
Finkel, T.3
-
39
-
-
0029073183
-
Inhibition of cellular ras prevents smooth muscle cell proliferation after vascular injury in vivo
-
Indolfi, C., E. V. Avvedimento, A. Rapacciuolo, E. Di Lornzo, G. Esposito, E. Stabile, A. Feliciello, E. Mele, P. Giuliano, G. Condorelli, and M. Chiariello. Inhibition of cellular ras prevents smooth muscle cell proliferation after vascular injury in vivo. Nature Med. 1:541-545 (1995).
-
(1995)
Nature Med.
, vol.1
, pp. 541-545
-
-
Indolfi, C.1
Avvedimento, E.V.2
Rapacciuolo, A.3
Di Lornzo, E.4
Esposito, G.5
Stabile, E.6
Feliciello, A.7
Mele, E.8
Giuliano, P.9
Condorelli, G.10
Chiariello, M.11
-
40
-
-
0027978302
-
Transcatheter delivery of c-myc antisense oligomers reduces neointimal formation in a porcine model of coronary artery balloon injury
-
Shi, Y., A. Fard, A. Galeo, H. G. Hutchinson, P. Vermani, G. R. Dodge, D. J. Hall, F. Shaheen, and A. Zalewski. Transcatheter delivery of c-myc antisense oligomers reduces neointimal formation in a porcine model of coronary artery balloon injury. Circulation 90:944-951 (1994).
-
(1994)
Circulation
, vol.90
, pp. 944-951
-
-
Shi, Y.1
Fard, A.2
Galeo, A.3
Hutchinson, H.G.4
Vermani, P.5
Dodge, G.R.6
Hall, D.J.7
Shaheen, F.8
Zalewski, A.9
|