메뉴 건너뛰기




Volumn 66, Issue 2, 1996, Pages 249-254

Cancer-associated mis-sense and deletion mutations impair p16(INK4) CDK inhibitory activity

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE; HYBRID PROTEIN;

EID: 0029990515     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19960410)66:2<249::AID-IJC19>3.0.CO;2-7     Document Type: Article
Times cited : (70)

References (25)
  • 2
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
    • HANNON, G.J. and BEACH, D., p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest. Nature (Lond.), 371, 257-261 (1994).
    • (1994) Nature (Lond.) , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 3
    • 0028918388 scopus 로고
    • Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
    • HIRAI, H., ROUSSEL, M.F., KATO, J.Y., ASHMUN, R.A. and SHERR, C.J., Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. Mol. cell. Biol., 15, 2672-2681 (1995).
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2672-2681
    • Hirai, H.1    Roussel, M.F.2    Kato, J.Y.3    Ashmun, R.A.4    Sherr, C.J.5
  • 5
    • 0026021882 scopus 로고
    • Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product
    • KAELIN, W., JR., PALLAS, D.C., DECAPRIO, J.A., KAYE, F.J. and LIVINGSTON, D.M., Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product. Cell, 64, 521-532 (1991).
    • (1991) Cell , vol.64 , pp. 521-532
    • Kaelin Jr., W.1    Pallas, D.C.2    Decaprio, J.A.3    Kaye, F.J.4    Livingston, D.M.5
  • 6
    • 0028940722 scopus 로고
    • Cell-cycle regulators and cancer
    • KAMB, A., Cell-cycle regulators and cancer. Trends Genet., 11, 136-140 (1995).
    • (1995) Trends Genet. , vol.11 , pp. 136-140
    • Kamb, A.1
  • 8
    • 0028085975 scopus 로고
    • Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus
    • KAMB, A. and 23 OTHERS, Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nature (Genet.), 8, 23-26 (1994b).
    • (1994) Nature (Genet.) , vol.8 , pp. 23-26
    • Kamb, A.1
  • 9
    • 0027973043 scopus 로고
    • 1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation
    • 1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation. Cell, 79, 487-496 (1994).
    • (1994) Cell , vol.79 , pp. 487-496
    • Kato, J.Y.1    Matsuoka, M.2    Polyak, K.3    Massagué, J.4    Sherr, C.J.5
  • 10
    • 0029052951 scopus 로고
    • Tumourderived p16 alleles encoding proteins defective in cell-cycle inhibition
    • KOH, J., ENDERS, G.H., DYNLACHT, B.D. and HARLOW, E., Tumourderived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature (Lond.), 375, 506-510 (1995).
    • (1995) Nature (Lond.) , vol.375 , pp. 506-510
    • Koh, J.1    Enders, G.H.2    Dynlacht, B.D.3    Harlow, E.4
  • 12
    • 0027943714 scopus 로고
    • Activation of cyclin-dependent kinase 4 (CDK4) by mouse MO15-associated kinase
    • MATSUOKA, M., KATO, J., FISHER, R.P., MORGAN, D.O. and SHERR, C.J., Activation of cyclin-dependent kinase 4 (CDK4) by mouse MO15-associated kinase. Mol. cell. Biol., 14, 7265-7275 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7265-7275
    • Matsuoka, M.1    Kato, J.2    Fisher, R.P.3    Morgan, D.O.4    Sherr, C.J.5
  • 13
    • 0028983491 scopus 로고
    • Growth suppression by p16INK4 requires functional retinoblastoma protein
    • MEDEMA, R.H., HERRERA, R.E., LAM, F. and WEINBERG, R.A., Growth suppression by p16INK4 requires functional retinoblastoma protein. Proc. nat. Acad, Sci. (Wash.), 92, 6289-6293 (1995).
    • (1995) Proc. Nat. Acad, Sci. (Wash.) , vol.92 , pp. 6289-6293
    • Medema, R.H.1    Herrera, R.E.2    Lam, F.3    Weinberg, R.A.4
  • 15
    • 0027374511 scopus 로고
    • The membrane-binding domain of ankyrin contains four independently folded subdomains, each comprised of six ankyrin repeats
    • MICHAELY, P. and BENNKTT, V., The membrane-binding domain of ankyrin contains four independently folded subdomains, each comprised of six ankyrin repeats. J. biol. Chem., 268, 22703-22709 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 22703-22709
    • Michaely, P.1    Bennktt, V.2
  • 16
    • 0028338514 scopus 로고
    • Frequent somatic mutation of the MTS1/CDK4I (multiple tumor suppressor/cyclin-dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma
    • MORI, T., MIURA, K., AOKI, T., NISHIHIRA, T., MORI, S. and NAKAMURA, Y., Frequent somatic mutation of the MTS1/CDK4I (multiple tumor suppressor/cyclin-dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma. Cancer Res., 54, 3396-3397 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 3396-3397
    • Mori, T.1    Miura, K.2    Aoki, T.3    Nishihira, T.4    Mori, S.5    Nakamura, Y.6
  • 17
    • 0028275733 scopus 로고
    • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • NOBORI, T., MIURA, K., WU, D.J., LOIS, A., TAKABAYASHI, K. and CARSON, D.A., Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (Lond.), 368, 753-756 (1994).
    • (1994) Nature (Lond.) , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayashi, K.5    Carson, D.A.6
  • 18
    • 0028894785 scopus 로고
    • Functional domains of pho81p, an inhibitor of pho85p protein kinase, in the transduction pathway of p-i signals in Saccharomyces cerevisiae
    • OGAWA, N., NOGUCHI, K.I., SAWAL, H., YAMASHITA, Y., YOMPAKDEE, C. and OSHIMA, Y., Functional domains of pho81p, an inhibitor of pho85p protein kinase, in the transduction pathway of p-i signals in Saccharomyces cerevisiae. Mol. cell. Biol., 15, 997-1004 (1995).
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 997-1004
    • Ogawa, N.1    Noguchi, K.I.2    Sawal, H.3    Yamashita, Y.4    Yompakdee, C.5    Oshima, Y.6
  • 19
    • 0027173109 scopus 로고
    • Cyclins and cyclin-dependent kinases: Take your partners
    • PINES, J., Cyclins and cyclin-dependent kinases: take your partners. Trends biochem. Sci., 18, 195-197 (1993).
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 195-197
    • Pines, J.1
  • 21
    • 0028931152 scopus 로고
    • Inhibition of ras-induced proliferation and cellular transformation by p16INK4
    • SERRANO, M., GOMEZ-LAHOZ, E., DEPINHO, R.A., BEACH, D. and BAR-SAGI, D., Inhibition of ras-induced proliferation and cellular transformation by p16INK4. Science, 267, 249-252 (1995).
    • (1995) Science , vol.267 , pp. 249-252
    • Serrano, M.1    Gomez-Lahoz, E.2    Depinho, R.A.3    Beach, D.4    Bar-Sagi, D.5
  • 22
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • SERRANO, M., HANNON, G.J. and BEACH, D., A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature (Lond.), 366, 704-707 (1993).
    • (1993) Nature (Lond.) , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 23
    • 0029071657 scopus 로고
    • D-type cyclins
    • SHERR, C.J., D-type cyclins. Trends biol. Sci., 20, 187-190 (1995).
    • (1995) Trends Biol. Sci. , vol.20 , pp. 187-190
    • Sherr, C.J.1
  • 24
    • 0028862489 scopus 로고
    • Biochemical and mutagenic analysis of the melanoma tumour suppressor gene product/p16
    • WICK, S.T., DUBAY, M.M., IMANIL, I. and BRIZUELA, L., Biochemical and mutagenic analysis of the melanoma tumour suppressor gene product/p16. Oncogene, 11, 2013-2019 (1995).
    • (1995) Oncogene , vol.11 , pp. 2013-2019
    • Wick, S.T.1    Dubay, M.M.2    Imanil, I.3    Brizuela, L.4
  • 25
    • 0028169236 scopus 로고
    • p21-containing cyclin kinases exist in both active and inactive states
    • ZHANG, H., HANNON, G.J. and BEACH, D., p21-containing cyclin kinases exist in both active and inactive states. Genes Develop., 8, 1750-1758 (1994).
    • (1994) Genes Develop. , vol.8 , pp. 1750-1758
    • Zhang, H.1    Hannon, G.J.2    Beach, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.