Crystal structure of the CDK4/6 inhibitory protein p18(INK4C) provides insights into ankyrin-like repeat structure/function and tumor-derived p16(INK4) mutations

Nature Structural Biology

Volumn 5, Issue 1, 1998, Pages 74-81

  Venkataramani, Ravichandran ^a   Swaminathan, Kunchithapadam ^a,b   Marmorstein, Ronen ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; HELIX LOOP HELIX PROTEIN; PROTEIN P16;

ARTICLE; CELL CYCLE; CRYSTAL STRUCTURE; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANKYRIN REPEAT; CARRIER PROTEINS; CELL CYCLE PROTEINS; CONSENSUS SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYCLIN-DEPENDENT KINASE 6; CYCLIN-DEPENDENT KINASE INHIBITOR P18; CYCLIN-DEPENDENT KINASES; ENZYME INHIBITORS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEOPLASMS; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR SUPPRESSOR PROTEINS;

EID: 0031985318     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb0198-74     Document Type: Article

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