Lithium increases tyrosine hydroxylase levels both in vivo and in vitro

Journal of Neurochemistry

Volumn 70, Issue 4, 1998, Pages 1768-1771

  Chen, Guang ^a   Yuan, Pei Xong ^a   Jiang, Yi Ming ^a   Huang, Li Dong ^a   Manji, Husseini K ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activator protein 1; Glycogen synthase kinase 3; Lithium; Manic depressive illness; Tyrosine hydroxylase

Indexed keywords

LITHIUM; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG ACTIVITY; DRUG SCREENING; FRONTAL CORTEX; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE INDUCTION; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MALE; MANIC DEPRESSIVE PSYCHOSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031930118     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.70041768.x     Document Type: Article

References (21)

1. Boyle W. J., Smeal T., Defize L. H., Angel P., Woodgett J. R., Karin M., and Hunter T. (1991) Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity. Cell 64, 573-584.
2. Chen G., Yuan P.-X., Hawver D. B., Potter W. Z., and Manji H. K. (1997) Increase in AP-1 transcription factor DNA binding activity by valproic acid. Neuropsychopharmacology 16, 238-245.
3. Gann L. G. and Roskoski R. Jr. (1995) Thermal stability and CD analysis of rat tyrosine hydroxylase. Biochemistry 34, 252-256.
4. Goodwin F. K. and Jamison K. R. (1990) Manic-Depressive Illness. Oxford University Press, New York.
5. Hedgepeth C. M., Conrad L. J., Zhang J., Huang H. C., Lee V. M. Y., and Klein P. S. (1997) Activation of the Wnt signaling pathway: a molecular mechanism for lithium action. Dev. Biol. 185, 82-91.
6. Hughes P. and Dragunow M. (1995) Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system. Pharmacol. Rev. 47, 133-178.
7. Hyman S. E. and Nestler E. J. (1996) Initiation and adaptation: a paradigm for understanding psychotropic drug action. Am. J. Psychiatry 153, 151-162.
8. Klein P. S. and Melton D. A. (1996) A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. USA 93, 8455-8459.
9. Kumer S. C. and Vrana K. E. (1996) Intricate regulation of tyrosine hydroxylase activity and gene expression. J. Neurochem. 67, 443-461.
10. Lanièce P., Hir H. L., Bodeau-Péan S., Charon Y., Valentin L., Thermes C., Mallet J., and Dumas S. (1996) A novel rat tyrosine hydroxylase mRNA species generated by alternative splicing. J. Neurochem. 66, 1819-1825.
11. Lenox R. H. and Manji H. K. (1995) Lithium, in American Psychiatric Press Textbook of Psychopharmacology (Nemeroff C. B. and Schatzberg A. F., eds), pp. 303-350. American Psychiatric Press, Washington, D.C.
12. Manji H. K. and Potter W. Z. (1997) Monoaminergic mechanisms, in Bipolar Disorder: Biological Models and Their Clinical Application (Joffe R. T. and Young L. T., eds), pp. 1-40. Marcel Dekker, New York.
13. Manji H. K., Potter W. Z., and Lenox R. H. (1995) Signal transduction pathways. Molecular targets for lithium's actions. Arch. Gen. Psychiatry 52, 531-543.
14. Ozaki N. and Chuang D.-M. (1997) Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain. J. Neurochem. 69, 2336-2344.
15. Schou M. (1991) Clinical aspects of lithium in psychiatry, in Lithium and the Cell (Birch N. J., ed), pp. 1-6. Academic Press, London.
16. Schussler N., Boularand S., Li J. Y., Peillon F., Mallet J., and Biguet N. F. (1995) Multiple tyrosine hydroxylase transcripts and immunoreactive forms in the rat: differential expression in anterior pituitary and adrenal gland. J. Neurosci. Res. 42, 846-854.
17. Smyth C., Kalsi G., Brynjolfsson J., O'Neill J., Curtis D., Rifkin L., Moloney E., Murphy P., Sherrington R., Pepsson H., and Gurling H. (1996) Further tests for linkage of bipolar affective disorder to the tyrosine hydroxylase gene locus on chromosome 11p15 in a new series of multiplex British affective disorder pedigrees. Am. J. Psychiatry 153, 271-274.
18. Souery D., Lipp O., Mahieu B., Mendelbaum K., DeMartelaer V., Van Broeckhoven C., and Mendlewicz J. (1996) Association study of bipolar disorder with candidate genes involved in catecholaminergic neurotransmission: DRD2, DRD3, DAT1 and TH genes. Am. J. Med. Genet. 67, 551-555.
19. Stambolic V., Ruel Laurent R., and Woodgett J. R. (1996) Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr. Biol. 6, 1664-1668.
20. Vyas S., Faucon B. N., and Mallet J. (1990) Transcriptional and post-transcriptional regulation of tyrosine hydroxylase gene by protein kinase C. EMBO J. 9, 3707-3712.
21. Yuan P. X., Chen G., and Manji H. K. (1996) Concordant regulation of gene expression by lithium and valproic acid in vitro. Soc. Neurosci. Abstr. 22, 237.