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Volumn 156, Issue 10, 1999, Pages 1506-1514

Molecular mechanisms underlying mood stabilization in manic-depressive illness: The phenotype challenge

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOGEN SYNTHASE; LITHIUM; PROTEIN BCL 2; PROTEIN KINASE C;

EID: 0032870743     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.156.10.1506     Document Type: Review
Times cited : (84)

References (70)
  • 2
    • 0032993716 scopus 로고    scopus 로고
    • Effects of lithium treatment and its discontinuation in bipolar manic-depressive disorders
    • Baldessarini RJ, Tondo L, Hennen J: Effects of lithium treatment and its discontinuation in bipolar manic-depressive disorders. J Clin Psychiatry 1999; 60(suppl 2):77-84
    • (1999) J Clin Psychiatry , vol.60 , Issue.SUPPL. 2 , pp. 77-84
    • Baldessarini, R.J.1    Tondo, L.2    Hennen, J.3
  • 4
    • 0029044932 scopus 로고
    • Signal transduction pathways: Molecular targets for lithium's actions
    • Manji HK, Potter WZ, Lenox RH: Signal transduction pathways: molecular targets for lithium's actions. Arch Gen Psychiatry 1995; 52:531-543
    • (1995) Arch Gen Psychiatry , vol.52 , pp. 531-543
    • Manji, H.K.1    Potter, W.Z.2    Lenox, R.H.3
  • 5
    • 0032947795 scopus 로고    scopus 로고
    • Anti-bipolar therapy: Mechanism of action of lithium
    • Jope RS: Anti-bipolar therapy: mechanism of action of lithium. Mol Psychiatry 1999; 4:117-128
    • (1999) Mol Psychiatry , vol.4 , pp. 117-128
    • Jope, R.S.1
  • 7
    • 0023461332 scopus 로고
    • Role of receptor coupling to phosphoinositide metabolism in the therapeutic action of lithium
    • Lenox RH: Role of receptor coupling to phosphoinositide metabolism in the therapeutic action of lithium. Adv Exp Biol Med 1987; 221:515-530
    • (1987) Adv Exp Biol Med , vol.221 , pp. 515-530
    • Lenox, R.H.1
  • 8
    • 0030032338 scopus 로고    scopus 로고
    • Initiation and adaptation: A paradigm for understanding psychotropic drug action
    • Hyman SE, Nestler EJ: Initiation and adaptation: a paradigm for understanding psychotropic drug action. Am J Psychiatry 1996; 153:151-162
    • (1996) Am J Psychiatry , vol.153 , pp. 151-162
    • Hyman, S.E.1    Nestler, E.J.2
  • 9
    • 0029047309 scopus 로고
    • Genetic determinants of human hypertension
    • Lifton RP: Genetic determinants of human hypertension. Proc Natl Acad Sci USA 1995; 92:8545-8551
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8545-8551
    • Lifton, R.P.1
  • 11
    • 0023185610 scopus 로고
    • Interactions among lithium, calcium, diacylglycerides, and phorbol esters in the regulation of adrenocorticotropin hormone release from AtT-20 cells
    • Reisine T, Zatz M: Interactions among lithium, calcium, diacylglycerides, and phorbol esters in the regulation of adrenocorticotropin hormone release from AtT-20 cells. J Neurochem 1987; 49:884-889
    • (1987) J Neurochem , vol.49 , pp. 884-889
    • Reisine, T.1    Zatz, M.2
  • 12
    • 0030473078 scopus 로고    scopus 로고
    • A novel action of lithium: Stimulation of glutamate release and inositol 1,4,5 trisphosphate accumulation via activation of the N-methyl D-aspartate receptor in monkey and mouse cerebral cortex slices
    • Hokin LE, Dixon JF, Los GV: A novel action of lithium: stimulation of glutamate release and inositol 1,4,5 trisphosphate accumulation via activation of the N-methyl D-aspartate receptor in monkey and mouse cerebral cortex slices. Adv Enzyme Regul 1996; 36:229-244
    • (1996) Adv Enzyme Regul , vol.36 , pp. 229-244
    • Hokin, L.E.1    Dixon, J.F.2    Los, G.V.3
  • 13
    • 0021251872 scopus 로고
    • Effects of lithium and angiotensin-stimulated phosphatidylinositol turnover and aldosterone production in adrenal glomerulosa cells: A possible causal relationship
    • Balla T, Enyedi P, Hunyady L, Spat A: Effects of lithium and angiotensin-stimulated phosphatidylinositol turnover and aldosterone production in adrenal glomerulosa cells: a possible causal relationship. FEBS Lett 1984; 171:179-182
    • (1984) FEBS Lett , vol.171 , pp. 179-182
    • Balla, T.1    Enyedi, P.2    Hunyady, L.3    Spat, A.4
  • 14
    • 0022505466 scopus 로고
    • Lithium dampens neurotransmitter response in smooth muscle: Relevance to action in affective illness
    • Menkes HA, Baraban JM, Freed AN, Snyder SH: Lithium dampens neurotransmitter response in smooth muscle: relevance to action in affective illness. Proc Natl Acad Sci USA 1986; 83:5727-5730
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5727-5730
    • Menkes, H.A.1    Baraban, J.M.2    Freed, A.N.3    Snyder, S.H.4
  • 15
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein PS, Melton DA: A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci USA 1996; 93: 8455-8459
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 16
    • 0027069613 scopus 로고
    • Rhythms and the pharmacology of lithium
    • Klemfuss H: Rhythms and the pharmacology of lithium. Pharmacol Ther 1992; 56:53-78
    • (1992) Pharmacol Ther , vol.56 , pp. 53-78
    • Klemfuss, H.1
  • 17
    • 0026897028 scopus 로고
    • Spontaneous recovery of deficits in spatial memory and cholinergic potentiation of NMDA in CA1 neurons during chronic lithium treatment
    • Richter-Levin G, Markram H, Segal M: Spontaneous recovery of deficits in spatial memory and cholinergic potentiation of NMDA in CA1 neurons during chronic lithium treatment. Hippocampus 1992; 2:279-286
    • (1992) Hippocampus , vol.2 , pp. 279-286
    • Richter-Levin, G.1    Markram, H.2    Segal, M.3
  • 18
    • 0022908227 scopus 로고
    • Lithium suppresses seizure susceptibility in pentylenetetrazol-kindled rats
    • Schmidt J: Lithium suppresses seizure susceptibility in pentylenetetrazol-kindled rats. Biomed Biochim Acta 1986; 45: 1167-1172
    • (1986) Biomed Biochim Acta , vol.45 , pp. 1167-1172
    • Schmidt, J.1
  • 19
    • 0020596356 scopus 로고
    • Systemic cholinergic agents induce seizures and brain damage in lithium-treated rats
    • Honchar MP, Olney JW, Sherman WR: Systemic cholinergic agents induce seizures and brain damage in lithium-treated rats. Science 1983; 220:323-325
    • (1983) Science , vol.220 , pp. 323-325
    • Honchar, M.P.1    Olney, J.W.2    Sherman, W.R.3
  • 20
    • 0032478088 scopus 로고    scopus 로고
    • Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx
    • Nonaka S, Hough CJ, Chuang DM: Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx. Proc Natl Acad Sci USA 1998;95:2642-2647
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2642-2647
    • Nonaka, S.1    Hough, C.J.2    Chuang, D.M.3
  • 21
    • 0033525538 scopus 로고    scopus 로고
    • Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression: A prominent role in neuroprotection against excitotoxicity
    • Chen RW, Chuang DM: Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression: a prominent role in neuroprotection against excitotoxicity. J Biol Chem 1999; 274:6039-6042
    • (1999) J Biol Chem , vol.274 , pp. 6039-6042
    • Chen, R.W.1    Chuang, D.M.2
  • 22
    • 85038140382 scopus 로고    scopus 로고
    • Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked?
    • in press
    • Manji HK, Moore GJ, Chen G: Lithium at 50: have the neuroprotective effects of this unique cation been overlooked? Biol Psychiatry (in press)
    • Biol Psychiatry
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 23
    • 0030726285 scopus 로고    scopus 로고
    • Lithium toxicity in yeast is due to the inhibition of RNA processing enzymes
    • Dichtl B, Stevens A, Tollerey D: Lithium toxicity in yeast is due to the inhibition of RNA processing enzymes. EMBO J 1997; 16:7184-7195
    • (1997) EMBO J , vol.16 , pp. 7184-7195
    • Dichtl, B.1    Stevens, A.2    Tollerey, D.3
  • 24
    • 0030856107 scopus 로고    scopus 로고
    • Upregulation of the expression of vasopressin gene in the paraventricular and supraoptic nuclei of the lithium-induced diabetes insipidus rat
    • Anai H, Ueta Y, Serino R, Bomura M, Kabashima N, Shibuya I, Takasugi M, Nakashima Y, Yamashita H: Upregulation of the expression of vasopressin gene in the paraventricular and supraoptic nuclei of the lithium-induced diabetes insipidus rat. Brain Res 1997; 772:161-166
    • (1997) Brain Res , vol.772 , pp. 161-166
    • Anai, H.1    Ueta, Y.2    Serino, R.3    Bomura, M.4    Kabashima, N.5    Shibuya, I.6    Takasugi, M.7    Nakashima, Y.8    Yamashita, H.9
  • 25
    • 0024341795 scopus 로고
    • Neuronal and developmental actions of lithium: A unifying hypothesis
    • Berridge MJ, Downes CP, Hanley MR: Neuronal and developmental actions of lithium: a unifying hypothesis. Cell 1989; 59: 411-419
    • (1989) Cell , vol.59 , pp. 411-419
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.R.3
  • 26
  • 27
    • 0026502059 scopus 로고
    • Inositol lipids and signal transduction in the nervous system: An update
    • Fisher SK, Heacock AM, Agranoff BW: Inositol lipids and signal transduction in the nervous system: an update. J Neurochem 1992; 58:18-38
    • (1992) J Neurochem , vol.58 , pp. 18-38
    • Fisher, S.K.1    Heacock, A.M.2    Agranoff, B.W.3
  • 28
    • 0025912111 scopus 로고
    • Lithium and the phosphoinositide cycle: An example of uncompetitive inhibition and its pharmacological consequences
    • Nahorski SR, Ragan CI, Challiss RAJ: Lithium and the phosphoinositide cycle: an example of uncompetitive inhibition and its pharmacological consequences. Trends Pharmacol Sci 1991; 12:297-303
    • (1991) Trends Pharmacol Sci , vol.12 , pp. 297-303
    • Nahorski, S.R.1    Ragan, C.I.2    Challiss, R.A.J.3
  • 29
    • 0027722019 scopus 로고
    • Biochemical, behavioral and clinical studies of the role of inositol in lithium treatment and depression
    • Kofman O, Belmaker RH: Biochemical, behavioral and clinical studies of the role of inositol in lithium treatment and depression. Biol Psychiatry 1993; 34:839-852
    • (1993) Biol Psychiatry , vol.34 , pp. 839-852
    • Kofman, O.1    Belmaker, R.H.2
  • 30
    • 0030693593 scopus 로고    scopus 로고
    • Lithium affects the ultradian clock of Schizosaccaromyces pombe by inhibition of inositol monophosphatase
    • Kippert F: Lithium affects the ultradian clock of Schizosaccaromyces pombe by inhibition of inositol monophosphatase. Biochem Soc Trans 1997; 25:8602
    • (1997) Biochem Soc Trans , vol.25 , pp. 8602
    • Kippert, F.1
  • 31
    • 0028219225 scopus 로고
    • Lithium and brain signal transduction systems
    • Jope RS, Williams MB: Lithium and brain signal transduction systems. Biochem Pharmacol 1994; 47:429-441
    • (1994) Biochem Pharmacol , vol.47 , pp. 429-441
    • Jope, R.S.1    Williams, M.B.2
  • 33
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signaling in intact cells
    • correction, 1997; 7:196
    • Stambolic V, Ruel LR, Woodgett JR: Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signaling in intact cells. Curr Biol 1996; 6:1664-1668; correction, 1997; 7:196
    • (1996) Curr Biol , vol.6 , pp. 1664-1668
    • Stambolic, V.1    Ruel, L.R.2    Woodgett, J.R.3
  • 34
    • 0031800971 scopus 로고    scopus 로고
    • Inhibition of GSK-3beta leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium
    • Lucas FR, Goold RG, Gordon-Weeks PR, Salinas PC: Inhibition of GSK-3beta leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium. J Cell Sci 1998; 111:1351-1361
    • (1998) J Cell Sci , vol.111 , pp. 1351-1361
    • Lucas, F.R.1    Goold, R.G.2    Gordon-Weeks, P.R.3    Salinas, P.C.4
  • 35
    • 0033014180 scopus 로고    scopus 로고
    • The mood stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3
    • Chen G, Huang LD, Jiang YM, Manji HK: The mood stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3. J Neurochem 1999; 72:1327-1330
    • (1999) J Neurochem , vol.72 , pp. 1327-1330
    • Chen, G.1    Huang, L.D.2    Jiang, Y.M.3    Manji, H.K.4
  • 37
    • 0027972567 scopus 로고
    • Long-term action of lithium: A role for transcriptional and posttranscriptional factors regulated by protein kinase C
    • Manji HK, Lenox RH: Long-term action of lithium: a role for transcriptional and posttranscriptional factors regulated by protein kinase C. Synapse 1994; 16:11-28
    • (1994) Synapse , vol.16 , pp. 11-28
    • Manji, H.K.1    Lenox, R.H.2
  • 38
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka Y: Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 1992; 258:607-613
    • (1992) Science , vol.258 , pp. 607-613
    • Nishizuka, Y.1
  • 40
    • 0027366278 scopus 로고
    • Lithium decreases membrane-associated protein kinase C in hippocampus: Selectivity for the alpha isozyme
    • Manji HK, Etcheberrigaray R, Chen G, Olds JL: Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme. J Neurochem 1993; 61: 2303-2310
    • (1993) J Neurochem , vol.61 , pp. 2303-2310
    • Manji, H.K.1    Etcheberrigaray, R.2    Chen, G.3    Olds, J.L.4
  • 41
    • 0033035485 scopus 로고    scopus 로고
    • Modulation of CNS signal transduction pathways and gene expression by mood stabilizing agents: Therapeutic implications
    • Manji HK, Bebchuk JM, Moore GJ, Glitz D, Hasanat K, Chen G: Modulation of CNS signal transduction pathways and gene expression by mood stabilizing agents: therapeutic implications. J Clin Psychiatry 1999; 60(suppl 2):27-39
    • (1999) J Clin Psychiatry , vol.60 , Issue.SUPPL. 2 , pp. 27-39
    • Manji, H.K.1    Bebchuk, J.M.2    Moore, G.J.3    Glitz, D.4    Hasanat, K.5    Chen, G.6
  • 42
    • 0026567408 scopus 로고
    • Chronic lithium administration alters a prominent PKC substrate in rat hippocampus
    • Lenox RH, Watson DG, Patel J, Ellis J: Chronic lithium administration alters a prominent PKC substrate in rat hippocampus. Brain Res 1992; 570:333-340
    • (1992) Brain Res , vol.570 , pp. 333-340
    • Lenox, R.H.1    Watson, D.G.2    Patel, J.3    Ellis, J.4
  • 43
    • 0030454553 scopus 로고    scopus 로고
    • Myristoylated alanine-rich C kinase substrate (MARCKS): A molecular target for the therapeutic action of mood stabilizers in the brain?
    • Lenox RH, McNamara RK, Watterson JM, Watson DG: Myristoylated alanine-rich C kinase substrate (MARCKS): a molecular target for the therapeutic action of mood stabilizers in the brain? J Clin Psychiatry 1996; 57(suppl 13):23-31
    • (1996) J Clin Psychiatry , vol.57 , Issue.SUPPL. 13 , pp. 23-31
    • Lenox, R.H.1    McNamara, R.K.2    Watterson, J.M.3    Watson, D.G.4
  • 44
    • 0027944371 scopus 로고
    • Chronic sodium valproate selectively decreases protein kinase C α and ε in vitro
    • Chen G, Manji HK, Hawver DB, Wright CB, Potter WZ: Chronic sodium valproate selectively decreases protein kinase C α and ε in vitro. J Neurochem 1994; 63:2361-2364
    • (1994) J Neurochem , vol.63 , pp. 2361-2364
    • Chen, G.1    Manji, H.K.2    Hawver, D.B.3    Wright, C.B.4    Potter, W.Z.5
  • 46
    • 0002716220 scopus 로고
    • Proto-oncogenes: Beyond second messengers
    • Edited by Bloom FE, Kupfer DJ. New York, Raven Press
    • Morgan JI, Curran TE: Proto-oncogenes: beyond second messengers, in Psychopharmacology: The Fourth Generation of Progress. Edited by Bloom FE, Kupfer DJ. New York, Raven Press, 1995, pp 631-642
    • (1995) Psychopharmacology: The Fourth Generation of Progress , pp. 631-642
    • Morgan, J.I.1    Curran, T.E.2
  • 47
    • 0032528112 scopus 로고    scopus 로고
    • Differential effects of mood stabilizers on Fos/Jun proteins and AP-1 DNA binding activity in human neuroblastoma SH-SY5Y cells
    • Asghari V, Wang JF, Reiach JS, Young LT: Differential effects of mood stabilizers on Fos/Jun proteins and AP-1 DNA binding activity in human neuroblastoma SH-SY5Y cells. Brain Res Mol Brain Res 1998; 58:95-102
    • (1998) Brain Res Mol Brain Res , vol.58 , pp. 95-102
    • Asghari, V.1    Wang, J.F.2    Reiach, J.S.3    Young, L.T.4
  • 48
    • 0030723121 scopus 로고    scopus 로고
    • Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain
    • Ozaki N, Chuang DM: Lithium increases transcription factor binding to AP-1 and cyclic AMP-responsive element in cultured neurons and rat brain. J Neurochem 1997; 69:2336-2344
    • (1997) J Neurochem , vol.69 , pp. 2336-2344
    • Ozaki, N.1    Chuang, D.M.2
  • 49
    • 0030017489 scopus 로고    scopus 로고
    • Intricate regulation of tyrosine hydroxylase activity and gene expression
    • Kumer SC, Vrana KE: Intricate regulation of tyrosine hydroxylase activity and gene expression. J Neurochem 1996; 67:443-461
    • (1996) J Neurochem , vol.67 , pp. 443-461
    • Kumer, S.C.1    Vrana, K.E.2
  • 50
    • 0031930118 scopus 로고    scopus 로고
    • Lithium increases tyrosine hydroxylase levels both in vivo and in vitro
    • Chen G, Yuan PX, Jiang Y, Huang LD, Manji HK: Lithium increases tyrosine hydroxylase levels both in vivo and in vitro. J Neurochem 1998; 70:1768-1771
    • (1998) J Neurochem , vol.70 , pp. 1768-1771
    • Chen, G.1    Yuan, P.X.2    Jiang, Y.3    Huang, L.D.4    Manji, H.K.5
  • 54
    • 0026674886 scopus 로고
    • Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction
    • Liang P, Pardee AB: Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 1992; 257:967-971
    • (1992) Science , vol.257 , pp. 967-971
    • Liang, P.1    Pardee, A.B.2
  • 55
    • 0345114742 scopus 로고    scopus 로고
    • Preferential identification of differentially expressed mRNAs of moderate to low abundance in a microscopic system using selected primers
    • Edited by Siebert P, Larrick JW. Natick, Mass, BioTechniques Books (Eaton Publishing)
    • Ikonomov OC, Jacob MH: Preferential identification of differentially expressed mRNAs of moderate to low abundance in a microscopic system using selected primers, in Gene Cloning and Analysis by RT-PCR. Edited by Siebert P, Larrick JW. Natick, Mass, BioTechniques Books (Eaton Publishing), 1998, pp 171-181
    • (1998) Gene Cloning and Analysis by RT-PCR , pp. 171-181
    • Ikonomov, O.C.1    Jacob, M.H.2
  • 56
    • 0029896911 scopus 로고    scopus 로고
    • Differential display PCR reveals increased expression of 2′,3′-cyclic nucleotide 3′-phosphodiesterase by lithium
    • Wang JF, Young LT: Differential display PCR reveals increased expression of 2′,3′-cyclic nucleotide 3′-phosphodiesterase by lithium. FEBS Lett 1996; 386:225-229
    • (1996) FEBS Lett , vol.386 , pp. 225-229
    • Wang, J.F.1    Young, L.T.2
  • 59
    • 0029791883 scopus 로고    scopus 로고
    • Do animal models have a place in the genetic analysis of quantitative human behavioral traits?
    • Flint J, Corley R: Do animal models have a place in the genetic analysis of quantitative human behavioral traits? J Mol Med 1996; 74:515-521
    • (1996) J Mol Med , vol.74 , pp. 515-521
    • Flint, J.1    Corley, R.2
  • 60
    • 0030221844 scopus 로고    scopus 로고
    • Synaptic targeting of ionotropic neurotransmitter receptors
    • Kirsch J, Meyer G, Betz H: Synaptic targeting of ionotropic neurotransmitter receptors. Mol Cell Neurosci 1996; 8:93-98
    • (1996) Mol Cell Neurosci , vol.8 , pp. 93-98
    • Kirsch, J.1    Meyer, G.2    Betz, H.3
  • 62
    • 0031975971 scopus 로고    scopus 로고
    • Integrative coordination of circadian mammalian diversity: Neuronal networks and peripheral clocks
    • Ikonomov OC, Stoynev AG, Shisheva AC: Integrative coordination of circadian mammalian diversity: neuronal networks and peripheral clocks. Prog Neurobiol 1998; 54:87-97
    • (1998) Prog Neurobiol , vol.54 , pp. 87-97
    • Ikonomov, O.C.1    Stoynev, A.G.2    Shisheva, A.C.3
  • 63
    • 0025021084 scopus 로고
    • Transplanted suprachiasmatic nucleus determines circadian period
    • Ralph MR, Foster RG, Davis FC, Menaker M: Transplanted suprachiasmatic nucleus determines circadian period. Science 1990; 247:975-978
    • (1990) Science , vol.247 , pp. 975-978
    • Ralph, M.R.1    Foster, R.G.2    Davis, F.C.3    Menaker, M.4
  • 64
    • 0028930156 scopus 로고
    • The circadian system and the therapeutics of the affective disorders
    • Healy D, Waterhouse JM: The circadian system and the therapeutics of the affective disorders. Pharmacol Ther 1995; 65: 241-263
    • (1995) Pharmacol Ther , vol.65 , pp. 241-263
    • Healy, D.1    Waterhouse, J.M.2
  • 66
    • 0026651347 scopus 로고
    • Effects of lithium hydroxybutyrate on circadian rhythms of rest-activity and sleep structure in experimental animals
    • Zamoshchina TA, Matveenko AV, Saratikov AS: Effects of lithium hydroxybutyrate on circadian rhythms of rest-activity and sleep structure in experimental animals. Biull Eksp Biol Med 1992; 113:152-154
    • (1992) Biull Eksp Biol Med , vol.113 , pp. 152-154
    • Zamoshchina, T.A.1    Matveenko, A.V.2    Saratikov, A.S.3
  • 67
    • 0027250281 scopus 로고
    • Evidence against a direct role for inositol phosphate metabolism in the circadian oscillator and the blue-light signal transduction pathway in Neurospora crassa
    • Lakin-Thomas PL: Evidence against a direct role for inositol phosphate metabolism in the circadian oscillator and the blue-light signal transduction pathway in Neurospora crassa. Biochem J 1993; 292:813-818
    • (1993) Biochem J , vol.292 , pp. 813-818
    • Lakin-Thomas, P.L.1
  • 68
    • 0028904194 scopus 로고
    • Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms
    • Welsh DK, Logothetis DE, Meister M, Reppert SM: Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 1995; 14:697-706
    • (1995) Neuron , vol.14 , pp. 697-706
    • Welsh, D.K.1    Logothetis, D.E.2    Meister, M.3    Reppert, S.M.4
  • 69
    • 0032543338 scopus 로고    scopus 로고
    • Circadian rhythms: New cogwheels in the clock-works
    • Schibler U: Circadian rhythms: new cogwheels in the clock-works. Nature 1998; 393:620-621
    • (1998) Nature , vol.393 , pp. 620-621
    • Schibler, U.1
  • 70
    • 0032102386 scopus 로고    scopus 로고
    • Three period homologs in mammals: Differential light responses in the suprachiasmatic circadian clock and oscillating transcripts outside of brain
    • Zylka MJ, Shearman LP, Weaver DR, Reppert SM: Three period homologs in mammals: differential light responses in the suprachiasmatic circadian clock and oscillating transcripts outside of brain. Neuron 1998; 20:1103-1110
    • (1998) Neuron , vol.20 , pp. 1103-1110
    • Zylka, M.J.1    Shearman, L.P.2    Weaver, D.R.3    Reppert, S.M.4


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