A randomized comparison of divalproex oral loading versus haloperidol in the initial treatment of acute psychotic mania

Journal of Clinical Psychiatry

Volumn 57, Issue 4, 1996, Pages 142-146

  McElroy, Susan L ^a   Keck Jr , Paul E ^a   Stanton, Sean P ^a   Tugrul, Karen C ^a   Bennett, Jerry A ^a   Strakowski, Stephen M ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HALOPERIDOL; VALPROATE SEMISODIUM;

ACUTE PSYCHOSIS; ADULT; AGED; AGITATION; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE CALCULATION; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFICACY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MANIA; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESTLESSNESS; TRANQUILIZING ACTIVITY;

ACUTE DISEASE; ADMINISTRATION, ORAL; ADULT; BASAL GANGLIA DISEASES; BIPOLAR DISORDER; HALOPERIDOL; HOSPITALIZATION; HUMANS; MALE; PROSPECTIVE STUDIES; PSYCHIATRIC STATUS RATING SCALES; SINGLE-BLIND METHOD; TREATMENT OUTCOME; VALPROIC ACID;

EID: 0029949167     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Modell JG, Lenox RH, Weiner S Inpatient clinical trial of lorazepam for the management of manic agitation. J Clin Psychopharmacol 1985;5: 109-113
2. Lenox RH, Modell JG, Weiner S. Acute treatment of manic agitation with lorazepam. Psychosomatics 1986;27:28-31
3. Dunner DL, Clayton PJ. Drug treatment of bipolar disorder. In: Meltzer HY, ed. Psychopharmacology: The Third Generation of Progress. New York. NY: Raven Press; 1987:1077-1083
4. Kane JM. The role of neuroleptics in manic-depressive illness J Clin Psychiatry 1988;49(11, suppl):12-13
5. Santos AB, Morton WA. Use of benzodiazepines to improve management of manic agitation. Hosp Community Psychiatry 1989;40: 1069-1071
6. Pnen RE, Potter WZ. NIMH workshop report on treatment of bipolar disorder. Psychopharmacol Bull 1990;26:409-427
7. Goodwin FK, Jamison KR. Manic-Depressive Illness. New York, NY: Oxford University Press: 1990
8. Gelenberg AJ. Psychoses. In: Gelenberg AJ, Bassuk EL, Schoonover SC, eds. The Practitioner's Guide to Psychoactive Drugs. 3rd ed. New York, NY: Plenum; 1991:125-178
9. Lenox RH, Newhouse PA, Creelman WL, et al. Adjunctive treatment of manic agitation with lorazepam versus haloperidol: a double-blind study. J Clin Psychiatry 1992;53;47-52
10. Gerner RH, Stanton A. Algorithm for patient management of acute manic states: lithium, valproate, or carbamazepine? J Clin Psychopharmacol 1992;12(suppl 1):57-63
11. Chouinard G, Annable L, Turiner L, et al. A double-blind, randomized, clinical trial of rapid tranquilization with IM clonazepam and IM haloperidol in agitated psychotic patients with manic symptoms. Can J Psychiatry 1993;38(suppl 4):114-121
12. American Psychiatric Association. Practice guideline for the treatment of patients with bipolar disorder. Am J Psychiatry 1994;151(12, suppl):1-36
13. Jefferson JW, Greist JH. Mood disorders. In: Hales RE, Yudofsky SC, Talbott JA, eds. The American Psychiatric Press Textbook of Psychiatry. 2nd ed. Washington, DC: American Psychiatric Press; 1994:465-494
14. Bowden CB. Treatment of bipolar disorder. In: Schatzberg AF, Nemeroff CB. eds. The American Psychiatric Press Textbook of Psychopharmacology. Washington, DC: American Psychiatric Press; 1995:603-614
15. Post RM. Mood disorders: somatic treatment. In: Kaplan HI, Sadock BJ, eds. Comprehensive Textbook of Psychiatry, vol 1. 6th ed. Baltimore, Md: Williams & Wilkins; 1995:1152-1177
16. Garfinkel PE, Stancer HC, Persad E. A comparison of haloperidol, lithium carbonate and their combination in the treatment of mania. J Affect Disord 1980;2:279-288
17. McElroy SL, Keck PE Jr. Antiepileptic drugs. In: Schatzberg AF, Nemeroff CB, eds. The American Psychiatric Press Textbook of Psychopharmacology. Washington, DC: American Psychiatric Press; 1995:351-375
18. Platman SR. A comparison of lithium carbonate and chlorpromazine in mania. Am J Psychiatry 1970;127:351-353
19. Shopsin B, Gershon S, Thompson H, et al. Psychoactive drugs in mania: a controlled comparison of lithium carbonate, chlorpromazine, and haloperidol. Arch Gen Psychiatry 1975;32:34-42
20. Prien RF, Caffey EM, Kleh CJ. Comparison of lithium carbonate and chlorpromazine in the treatment of mania: report of the Veterans Administration and National Institute of Mental Health Collaborative Study Group. Arch Gen Psychiatry 1972;26:146-153
21. Schou M. Special review: lithium in psychiatric therapy and prophylaxis J Psychiatr Res 1968;6:67-95
22. Johnston G, Gershon S, Burdock EI, et al. Controlled evaluation of lithium and chlorpromazine in the treatment of manic states: an interim report Compr Psychiatry 1968;9:563-573
23. Spring G, Schweid D, Gray C, et al. A double-blind comparison of lithium and chlorpromazine in the treatment of manic states Am J Psychiatry 1970;126:1306-1310
24. Johnson G, Gershon S, Burdock EI, et al. Comparative effects of lithium and chlorpromazine in the treatment of acute manic states. Br J Psychiatry 1971;119:267-276
25. Takahashi R, Sakuma A, Itoh K, et al. Comparison of efficacy of lithium carbonate and chlorpromazine in mania: report of collaborative study group on treatment of mania in Japan. Arch Gen Psychiatry 1975;32: 1310-1318
26. Janicak PG, Newman RH, Davis JM. Advances in the treatment of manic and related disorders: a reappraisal. Psychiatr Ann 1992;22:92-103
27. Morgan HG. The incidence of depressive symptoms during recovery from hypomania. Br J Psychiatry 1972;120:537-539
28. Kukopulos A, Reginaldi D, Laddomada P, et al. Course of the manic-depressive cycle and changes caused by treatments. Pharmakopsychiatr Neuropsychopharmakol 1980;13:156-167
29. Ahlfors UG, Baastrup PC, Dencker SJ, et al. Flupenthixol decanoate in recurrent manic-depressive illness: a comparison with lithium. Acta Psychiatr Scand 1981;64:226-237
30. Levine S. The management of resistant depression. Acta Psychiatr Belg 1986;86:141-151
31. Kane JM, Smith JM. Tardive dyskinesia: prevalence and risk factors. Arch Gen Psychiatry 1982;39:473-481
32. Mukherjee S, Rosen AM, Caracci G, et al. Persistent tardive dyskinesia in bipolar patients. Arch Gen Psychiatry 1986;43:342-346
33. Nasrallah HA, Churchill CM, Hamdan-Allan GA. Higher frequency of neuroleptic-induced dystonia in mania than in schizophrenia. Am J Psychiatry 1988;145:1455-1456
34. Kane JM, Jeste DV, Barnes TRE, et al. (The American Psychiatric Association Task Force on Tardive Dyskinesia). Tardive Dyskinesia: A Task Force Report of the American Psychiatric Association. Washington, DC: American Psychiatric Association; 1992
35. Keck PE Jr, Pope HG Jr, Cohen BM, et al. Risk factors for neuroleptic malignant syndrome: a case-control study. Arch Gen Psychiatry 1989;46: 914-918
36. Pope HG Jr, McElroy SL, Keck PE Jr, et al. Valproate in the treatment of acute mania: a placebo-controlled study. Arch Gen Psychiatry 1991;48: 62-68
37. Bowden CL, Brugger AM, Swann AC, et al. Efficacy of divalproex vs lithium and placebo in the treatment of mania. JAMA 1994;271:918-924
38. Keck PE Jr, McElroy SL, Tugrul KC, et al. Valproate oral loading in the treatment of acute mania. J Clin Psychiatry 1993;54:305-308
39. McElroy SL, Keck PE Jr, Tugrul KC, et al. Valproate as a loading treatment in acute mania. Neuropsychobiology 1993;27:146-149
40. Winter ME. Valproic acid. In: Koda-Kimble MA, Young LY, eds. Basic Clinical Pharmacokinetics. Spokane, Wash: Applied Therapeutics; 1988
41. Giround M, Dumas R. Pharmacokinetics of valproate in adults after a single loading dose. Arch Neurol 1989;46:13-14
42. Van Putten T, Marder SR, Mintz J, et al. Haloperidol plasma levels and clinical response: a therapeutic window relationship. Psychopharmacol Bull 1988;24:172-175
43. Wistedt B, Johanidesz G, Omerhodzic M, et al. Plasma haloperidol levels and clinical response in acute schizophrenia. Nordisk Psykiatrisk Tidsskrift 1984;19:9-13
44. Young RC, Biggs JT, Ziegler VE, et al. A rating scale for mania: reliability, validity, and sensitivity. Br J Psychiatry 1978;133:429-435
45. Andreasen NC. The Scale for Assessment of Positive Symptoms (SAPS). Iowa City, Iowa: University of Iowa; 1984