-
1
-
-
0025233576
-
Genetic and mutational analysis of the T-cell antigen receptor
-
Ashwell J.D., Klausner R.D. Genetic and mutational analysis of the T-cell antigen receptor. Ann Rev Immunol. 8:1990;139-167.
-
(1990)
Ann Rev Immunol
, vol.8
, pp. 139-167
-
-
Ashwell, J.D.1
Klausner, R.D.2
-
2
-
-
0027315182
-
T cell antigen receptor signal transduction: A tale of tails and cytoplasmic protein-tyrosine kinases
-
Weiss A. T cell antigen receptor signal transduction: a tale of tails and cytoplasmic protein-tyrosine kinases. Cell. 73:1993;209-212.
-
(1993)
Cell
, vol.73
, pp. 209-212
-
-
Weiss, A.1
-
3
-
-
0000722327
-
New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL)
-
Cambier J.C. New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL). Immunol Today. 16:1995;110.
-
(1995)
Immunol Today
, vol.16
, pp. 110
-
-
Cambier, J.C.1
-
4
-
-
0033534533
-
Adaptors and molecular scaffolds in immune cell signaling
-
Rudd C.E. Adaptors and molecular scaffolds in immune cell signaling. Cell. 96:1999;5-8.
-
(1999)
Cell
, vol.96
, pp. 5-8
-
-
Rudd, C.E.1
-
5
-
-
0030250114
-
Complex complexes: Signaling at the TCR
-
Wange R.L., Samelson L.E. Complex complexes: signaling at the TCR. Immunity. 5:1996;197-205.
-
(1996)
Immunity
, vol.5
, pp. 197-205
-
-
Wange, R.L.1
Samelson, L.E.2
-
6
-
-
0029874657
-
T cell antigen receptor signal transduction pathways
-
Cantrell D. T cell antigen receptor signal transduction pathways. Ann Rev Immunol. 14:1996;259-274.
-
(1996)
Ann Rev Immunol
, vol.14
, pp. 259-274
-
-
Cantrell, D.1
-
7
-
-
0028014460
-
Signal transduction by lymphocyte antigen receptors
-
Weiss A., Littman D.R. Signal transduction by lymphocyte antigen receptors. Cell. 76:1994;263-274.
-
(1994)
Cell
, vol.76
, pp. 263-274
-
-
Weiss, A.1
Littman, D.R.2
-
9
-
-
0027399703
-
Functional characterization of a signal transducing motif present in the T cell receptor ζ chain
-
Irving B.A., Chan A.C., Weiss A. Functional characterization of a signal transducing motif present in the T cell receptor ζ chain. J Exp Med. 177:1993;1093-1103.
-
(1993)
J Exp Med
, vol.177
, pp. 1093-1103
-
-
Irving, B.A.1
Chan, A.C.2
Weiss, A.3
-
10
-
-
0029094319
-
Altered T cell development in mice with a targeted mutation of the CD3- gene
-
Malissen M., Gillet A., Ardoiun L., Bouvier G., Trucy J., Ferrier P., Viver E., Malissen B. Altered T cell development in mice with a targeted mutation of the CD3- gene. EMBO J. 14:1995;4641-4653.
-
(1995)
EMBO J
, vol.14
, pp. 4641-4653
-
-
Malissen, M.1
Gillet, A.2
Ardoiun, L.3
Bouvier, G.4
Trucy, J.5
Ferrier, P.6
Viver, E.7
Malissen, B.8
-
11
-
-
0029584385
-
Early T-cell development in CD3-deficient mice
-
Tanaka Y., Ardoiun L., Gillet A., Lin S-Y, Magnan A., Malissen B., Malissen M. Early T-cell development in CD3-deficient mice. Immunol Rev. 148:1995;171-199.
-
(1995)
Immunol Rev
, vol.148
, pp. 171-199
-
-
Tanaka, Y.1
Ardoiun, L.2
Gillet, A.3
Lin, S.-Y.4
Magnan, A.5
Malissen, B.6
Malissen, M.7
-
12
-
-
0027199532
-
T cell development in mice that lack the ζ chain of the T cell antigen receptor compex
-
Love P.E., Shores E.W., Johnson M.D., Tremblay M.L., Lee E.J., Grinberg A., Huang S.P., Singer A., Westphal H. T cell development in mice that lack the ζ chain of the T cell antigen receptor compex. Science. 261:1993;918-921.
-
(1993)
Science
, vol.261
, pp. 918-921
-
-
Love, P.E.1
Shores, E.W.2
Johnson, M.D.3
Tremblay, M.L.4
Lee, E.J.5
Grinberg, A.6
Huang, S.P.7
Singer, A.8
Westphal, H.9
-
13
-
-
0027432384
-
-/-mice and identification of a novel T cell population in the intestine
-
-/-mice and identification of a novel T cell population in the intestine. EMBO J. 12:1993;4863-4875.
-
(1993)
EMBO J
, vol.12
, pp. 4863-4875
-
-
Liu, C.-P.1
Ueda, R.2
She, J.3
Sancho, J.4
Wang, B.5
Weddell, G.6
Loring, J.7
Kurahara, C.8
Dudley, E.C.9
Hayday, A.10
Terhorst, C.11
Huang, M.12
-
14
-
-
0027501806
-
T cell development in mice lacking the CD3-ζ/η gene
-
Malissen M., Gillet A., Rocha B., Trucy J., Brun N., Mazza G., Spanopoulou E., Guy-Grand D., Malissen B. T cell development in mice lacking the CD3-ζ/η gene. EMBO J. 12:1993;4347-4355.
-
(1993)
EMBO J
, vol.12
, pp. 4347-4355
-
-
Malissen, M.1
Gillet, A.2
Rocha, B.3
Trucy, J.4
Brun, N.5
Mazza, G.6
Spanopoulou, E.7
Guy-Grand, D.8
Malissen, B.9
-
15
-
-
0026544338
-
The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules
-
Wegener A-MK, Letourneur F., Hoeveler A., Brocker T., Luton F., Malissen B. The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell. 68:1992;83-95.
-
(1992)
Cell
, vol.68
, pp. 83-95
-
-
Wegener, A.-M.K.1
Letourneur, F.2
Hoeveler, A.3
Brocker, T.4
Luton, F.5
Malissen, B.6
-
16
-
-
0028051551
-
Role of TCR ζ chain in T cell development and selection
-
Shores E.W., Huang K., Tran T., Lee E., Grinberg A., Love P.E. Role of TCR ζ chain in T cell development and selection. Science. 266:1994;1047-1050.
-
(1994)
Science
, vol.266
, pp. 1047-1050
-
-
Shores, E.W.1
Huang, K.2
Tran, T.3
Lee, E.4
Grinberg, A.5
Love, P.E.6
-
17
-
-
0030897710
-
Role of multiple TCR ζ chain signaling motifs in selection of the T cell repertoire
-
Shores E.W., Tran T., Grinberg A., Sommers C.L., Shen H., Love P.E. Role of multiple TCR ζ chain signaling motifs in selection of the T cell repertoire. J Exp Med. 185:1997;893-900.
-
(1997)
J Exp Med
, vol.185
, pp. 893-900
-
-
Shores, E.W.1
Tran, T.2
Grinberg, A.3
Sommers, C.L.4
Shen, H.5
Love, P.E.6
-
18
-
-
0024446403
-
+thymocytes results in tyrosine phosphorylation of the T-cell receptor zeta chain
-
+thymocytes results in tyrosine phosphorylation of the T-cell receptor zeta chain. Nature. 341:1989;651-654.
-
(1989)
Nature
, vol.341
, pp. 651-654
-
-
Nakayama, T.1
Singer, A.2
Hsi, E.D.3
Samelson, L.E.4
-
19
-
-
0027228369
-
Constitutive tyrosine phosphorylation of the T cell receptor (TCR) ζ subunit: Regulation of TCR-associated protein kinase activity by TCR ζ
-
van Oers NSC, Tao W., Watts J.D., Johnson P., Aebersold R., Teh H-S. Constitutive tyrosine phosphorylation of the T cell receptor (TCR) ζ subunit: Regulation of TCR-associated protein kinase activity by TCR ζ Mol Cell Biol. 13:1993;5771-5780.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 5771-5780
-
-
Van Oers, N.S.C.1
Tao, W.2
Watts, J.D.3
Johnson, P.4
Aebersold, R.5
Teh, H.-S.6
-
20
-
-
0028535120
-
ZAP-70 is constitutively associated with tyrosine phosphorylated TCR ζ in murine thymocytes and lymph node T cells
-
van Oers NSC, Killeen N., Weiss A. ZAP-70 is constitutively associated with tyrosine phosphorylated TCR ζ in murine thymocytes and lymph node T cells. Immunity. 1:1994;675-685.
-
(1994)
Immunity
, vol.1
, pp. 675-685
-
-
Van Oers, N.S.C.1
Killeen, N.2
Weiss, A.3
-
21
-
-
0029866039
-
Lck regulates the tyrosine phosphorylation of the TCR subunits and ZAP-70 in murine thymocytes
-
van Oers NSC, Killeen N., Weiss A. Lck regulates the tyrosine phosphorylation of the TCR subunits and ZAP-70 in murine thymocytes. J Exp Med. 183:1996;1053-1062.
-
(1996)
J Exp Med
, vol.183
, pp. 1053-1062
-
-
Van Oers, N.S.C.1
Killeen, N.2
Weiss, A.3
-
22
-
-
0032211059
-
Differential requirements for ZAP-70 in TCR signaling and T cell development
-
Kadlecek T.A., van Oers NSC, Lefrancois L., Olson S., Finlay D., Chu D.H., Connolly K., Killeen N., Weiss A. Differential requirements for ZAP-70 in TCR signaling and T cell development. J Immunol. 161:1998;4688-4694.
-
(1998)
J Immunol
, vol.161
, pp. 4688-4694
-
-
Kadlecek, T.A.1
Van Oers, N.S.C.2
Lefrancois, L.3
Olson, S.4
Finlay, D.5
Chu, D.H.6
Connolly, K.7
Killeen, N.8
Weiss, A.9
-
23
-
-
0028988331
-
T cell receptor antagonists and partial agonists
-
Jameson S.C., Bevan M.J. T cell receptor antagonists and partial agonists. Immunity. 2:1995;1-11.
-
(1995)
Immunity
, vol.2
, pp. 1-11
-
-
Jameson, S.C.1
Bevan, M.J.2
-
24
-
-
0027967385
-
Partial T cell signaling: Altered phospho-ζ and lack of ZAP-70 recruitment in APL-induced T cell anergy
-
Sloan-Lancaster J., Shaw A.S., Rothbard J.B., Allen P.M. Partial T cell signaling: Altered phospho-ζ and lack of ZAP-70 recruitment in APL-induced T cell anergy. Cell. 79:1994;913-922.
-
(1994)
Cell
, vol.79
, pp. 913-922
-
-
Sloan-Lancaster, J.1
Shaw, A.S.2
Rothbard, J.B.3
Allen, P.M.4
-
25
-
-
0028902752
-
ζ phosphorylation without ZAP-70 activation induced by T cell receptor antagonists or partial agonists
-
Madrenas J., Wange R.L., Wang J.L., Isakov N., Samelson L.E., Germain R.N. ζ phosphorylation without ZAP-70 activation induced by T cell receptor antagonists or partial agonists. Science. 267:1995;515-518.
-
(1995)
Science
, vol.267
, pp. 515-518
-
-
Madrenas, J.1
Wange, R.L.2
Wang, J.L.3
Isakov, N.4
Samelson, L.E.5
Germain, R.N.6
-
26
-
-
0028973001
-
fyn protein expression in thymocyte subsets, peripheral T cells, NK cells, and lymphoid cell lines
-
fyn protein expression in thymocyte subsets, peripheral T cells, NK cells, and lymphoid cell lines. J Immunol. 155:1995;4236-4240.
-
(1995)
J Immunol
, vol.155
, pp. 4236-4240
-
-
Olszowy, M.W.1
Leuchtmann, P.L.2
Veillette, A.3
Shaw, A.S.4
-
27
-
-
0028288927
-
Role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signaling
-
Chan A.C., Desai D., Weiss A. Role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signaling. Ann Rev Immunol. 12:1994;555-592.
-
(1994)
Ann Rev Immunol
, vol.12
, pp. 555-592
-
-
Chan, A.C.1
Desai, D.2
Weiss, A.3
-
28
-
-
0028209548
-
Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases
-
Iwashima M., Irving B.A., van Oers NSC, Chan A.C., Weiss A. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science. 263:1994;1136-1139.
-
(1994)
Science
, vol.263
, pp. 1136-1139
-
-
Iwashima, M.1
Irving, B.A.2
Van Oers, N.S.C.3
Chan, A.C.4
Weiss, A.5
-
29
-
-
0026705903
-
Genetic evidence for the involvement of the Lck tyrosine kinase in signal transduction throught the T cell antigen receptor
-
Straus D., Weiss A. Genetic evidence for the involvement of the Lck tyrosine kinase in signal transduction throught the T cell antigen receptor. Cell. 70:1992;585-593.
-
(1992)
Cell
, vol.70
, pp. 585-593
-
-
Straus, D.1
Weiss, A.2
-
30
-
-
0028830744
-
A signaling pathway governing early thymocyte maturation
-
Anderson S.J., Perlmutter R.M. A signaling pathway governing early thymocyte maturation. Immunol Today. 16:1995;99-105.
-
(1995)
Immunol Today
, vol.16
, pp. 99-105
-
-
Anderson, S.J.1
Perlmutter, R.M.2
-
31
-
-
0030802798
-
Protein tyrosine kinases in thymocyte development
-
Cheng A.M., Cahn A.C. Protein tyrosine kinases in thymocyte development. Curr Opin Immunol. 9:1997;528-533.
-
(1997)
Curr Opin Immunol
, vol.9
, pp. 528-533
-
-
Cheng, A.M.1
Cahn, A.C.2
-
32
-
-
0026522204
-
Profound block in thymocyte development in mice lacking p56lck
-
Molina T.J., Kishihara K., Siderovski D.P., van Ewijk W, Narendran A., Timms E., Wakeham A., Paige C.J., Hartmann K-U, Veillette A., Davidson D., Mak T.W. Profound block in thymocyte development in mice lacking p56lck. Nature. 357:1992;161-164.
-
(1992)
Nature
, vol.357
, pp. 161-164
-
-
Molina, T.J.1
Kishihara, K.2
Siderovski, D.P.3
Van Ewijk, W.4
Narendran, A.5
Timms, E.6
Wakeham, A.7
Paige, C.J.8
Hartmann, K.-U.9
Veillette, A.10
Davidson, D.11
Mak, T.W.12
-
33
-
-
0029071585
-
Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function
-
Chan A.C., Dalton M., Johnson R., Kong G-H, Wang T., Thoma R., Kurosaki T. Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. EMBO J. 14:1995;2499-2508.
-
(1995)
EMBO J
, vol.14
, pp. 2499-2508
-
-
Chan, A.C.1
Dalton, M.2
Johnson R.Kong, G.-H.3
Wang, T.4
Thoma, R.5
Kurosaki, T.6
-
34
-
-
0028062116
-
Identification by electrospray ionization mass spectromoetry of the sites of tyrosine phosphorylation induced in activated Jurkat T cells on the protein tyrosine kinase ZAP-70
-
Watts J.D., Affolter M., Krebs D.L., Wange R.L., Samelson L.E., Aebersold R. Identification by electrospray ionization mass spectromoetry of the sites of tyrosine phosphorylation induced in activated Jurkat T cells on the protein tyrosine kinase ZAP-70. J Biol Chem. 269:1994;29520-29529.
-
(1994)
J Biol Chem
, vol.269
, pp. 29520-29529
-
-
Watts, J.D.1
Affolter, M.2
Krebs, D.L.3
Wange, R.L.4
Samelson, L.E.5
Aebersold, R.6
-
35
-
-
0029151944
-
Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70
-
Wange R.L., Guitian R., Isakov N., Watts J.D., Aebersold R., Samelson L.E. Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70. J Biol Chem. 270:1995;18730-18733.
-
(1995)
J Biol Chem
, vol.270
, pp. 18730-18733
-
-
Wange, R.L.1
Guitian, R.2
Isakov, N.3
Watts, J.D.4
Aebersold, R.5
Samelson, L.E.6
-
36
-
-
0026612411
-
fynmutant mice display differential signaling in thymocytes and peripheral T cells
-
fynmutant mice display differential signaling in thymocytes and peripheral T cells. Cell. 70:1992;741-750.
-
(1992)
Cell
, vol.70
, pp. 741-750
-
-
Stein, P.L.1
Lee, H.-M.2
Rich, S.3
Soriano, P.4
-
39
-
-
0030902281
-
Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling
-
Qian D., Lev S., van Oers NSC, Schlessinger J., Weiss A. Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling. J Exp Med. 185:1997;1253-1259.
-
(1997)
J Exp Med
, vol.185
, pp. 1253-1259
-
-
Qian, D.1
Lev, S.2
Van Oers, N.S.C.3
Schlessinger, J.4
Weiss, A.5
-
40
-
-
0030959305
-
Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen rceptor stimulated protein tyrosine kinases
-
Musci M.A., Hendricks-Taylor L.R., Motto D.G., Paskind M., Kamens J., Turck C.W., Koretzky G.A. Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen rceptor stimulated protein tyrosine kinases. J Biol Chem. 272:1997;11674-11677.
-
(1997)
J Biol Chem
, vol.272
, pp. 11674-11677
-
-
Musci, M.A.1
Hendricks-Taylor, L.R.2
Motto, D.G.3
Paskind, M.4
Kamens, J.5
Turck, C.W.6
Koretzky, G.A.7
-
41
-
-
0030737886
-
Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulate interleukin 2 production
-
daSilva A.J., Li Z., de Vera C, Canto E., Findell P., Rudd C.E. Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulate interleukin 2 production. Proc Natl Acad Sci USA. 94:1997;7493-7498.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7493-7498
-
-
DaSilva, A.J.1
Li, Z.2
De Vera, C.3
Canto, E.4
Findell, P.5
Rudd, C.E.6
-
42
-
-
0030294283
-
Fyn can partially substitute for Lck in T lymphocyte development
-
Groves T., Smiley P., Cooke M.P., Forbush K., Perlmutter R.M., Guidos C.J. Fyn can partially substitute for Lck in T lymphocyte development. Immunity. 5:1996;417-428.
-
(1996)
Immunity
, vol.5
, pp. 417-428
-
-
Groves, T.1
Smiley, P.2
Cooke, M.P.3
Forbush, K.4
Perlmutter, R.M.5
Guidos, C.J.6
-
43
-
-
0030293791
-
αβ T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases
-
van Oers NSC, Lowin-Kropf B., Finlay D., Connolly K., Weiss A. αβ T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases. Immunity. 5:1996;429-436.
-
(1996)
Immunity
, vol.5
, pp. 429-436
-
-
Van Oers, N.S.C.1
Lowin-Kropf, B.2
Finlay, D.3
Connolly, K.4
Weiss, A.5
-
44
-
-
0030996848
-
ZAP-70 protein tyrosine kinase is constitutively targeted to the T cell cortex independently of its SH2 domains
-
Huby R.D.J., Iwashima M., Weiss A., Ley S.C. ZAP-70 protein tyrosine kinase is constitutively targeted to the T cell cortex independently of its SH2 domains. J Cell Biol. 137:1997;1639-1649.
-
(1997)
J Cell Biol
, vol.137
, pp. 1639-1649
-
-
Huby, R.D.J.1
Iwashima, M.2
Weiss, A.3
Ley, S.C.4
-
45
-
-
0026483786
-
ZAP-70: A 70kD protein tyrosine kinase that associates with the TCR ζ chain
-
Chan A.C., Iwashima M., Turck C.W., Weiss A. ZAP-70: A 70kD protein tyrosine kinase that associates with the TCR ζ chain. Cell. 71:1992;649-662.
-
(1992)
Cell
, vol.71
, pp. 649-662
-
-
Chan, A.C.1
Iwashima, M.2
Turck, C.W.3
Weiss, A.4
-
46
-
-
0028216232
-
Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in T cell antigen receptor signalling
-
Chan A.C., van Oers NSC, Tran A., Turka L., Law C-L, Ryan J.C., Clark E.A., Weiss A. Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in T cell antigen receptor signalling. J Immunol. 152:1994;4758-4766.
-
(1994)
J Immunol
, vol.152
, pp. 4758-4766
-
-
Chan, A.C.1
Van Oers, N.S.C.2
Tran, A.3
Turka, L.4
Law, C.-L.5
Ryan, J.C.6
Clark, E.A.7
Weiss, A.8
-
47
-
-
0028877062
-
The pre-TCR complex is functionally coupled to the TCR ζ subunit. J Exp
-
van Oers NSC, von Boehmer H, Weiss A. The pre-TCR complex is functionally coupled to the TCR ζ subunit. J Exp. Med. 182:1995;1585-1590.
-
(1995)
Med
, vol.182
, pp. 1585-1590
-
-
Van Oers, N.S.C.1
Von Boehmer, H.2
Weiss, A.3
-
48
-
-
0009603378
-
-
Chu, DH, van, Oers, NSC, Malissen, M, Harris, J, Elder, M, Weiss, A, 1999.
-
(1999)
-
-
Chu, D.H.1
Van Oers, N.S.C.2
Malissen, M.3
Harris, J.4
Elder, M.5
Weiss, A.6
-
50
-
-
0028340167
-
ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency
-
Chan A.C., Kadlecek T.A., Elder M.E., Filipovich A.H., Kuo W-L, Iwashima M., Parslow T.G., Weiss A. ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science. 264:1994;1599-1601.
-
(1994)
Science
, vol.264
, pp. 1599-1601
-
-
Chan, A.C.1
Kadlecek, T.A.2
Elder, M.E.3
Filipovich, A.H.4
Kuo, W.-L.5
Iwashima, M.6
Parslow, T.G.7
Weiss, A.8
-
51
-
-
0028292001
-
Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase
-
Elder M.E., Lin D., Clever J., Chan A.C., Hope T.J., Weiss A., Parslow T. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science. 264:1994;1596-1599.
-
(1994)
Science
, vol.264
, pp. 1596-1599
-
-
Elder, M.E.1
Lin, D.2
Clever, J.3
Chan, A.C.4
Hope, T.J.5
Weiss, A.6
Parslow, T.7
-
52
-
-
0029133646
-
Essential role for ZAP-70 in both positive and negative selection of thymocytes
-
Negishi I., Motoyama N., Nakayama K-I, Nakayama K., Senju S., Hatakeyama S., Zhang Q., Chan A.C., Loh D.Y. Essential role for ZAP-70 in both positive and negative selection of thymocytes. Nature. 376:1995;435-438.
-
(1995)
Nature
, vol.376
, pp. 435-438
-
-
Negishi, I.1
Motoyama, N.2
Nakayama, K.-I.3
Nakayama, K.4
Senju, S.5
Hatakeyama, S.6
Zhang, Q.7
Chan, A.C.8
Loh, D.Y.9
-
53
-
-
0030802186
-
A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development
-
Wiest D.L., Ashe J.M., Howcroft T.K., Lee H-M, Kemper D.M., Negishi I., Singer D.S., Singer A., Abe R. A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development. Immunity. 6:1997;663-671.
-
(1997)
Immunity
, vol.6
, pp. 663-671
-
-
Wiest, D.L.1
Ashe, J.M.2
Howcroft, T.K.3
Lee, H.-M.4
Kemper, D.M.5
Negishi, I.6
Singer, D.S.7
Singer, A.8
Abe, R.9
-
54
-
-
0032498231
-
LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
-
Zhang W., Sloan-Lancaster J., Kitchen J., Trible R.P., Samelson L.E. LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell. 92:1998;83-92.
-
(1998)
Cell
, vol.92
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
Trible, R.P.4
Samelson, L.E.5
-
55
-
-
0028889302
-
Perinatal lethality and blocked B cell development in mice lacking the tyrosine kinase Syk
-
Turner M., Mee P.J., Costello P.S., Williams O., Price A.A., Duddy L.P., Furlong M.T., Geahlen R.L., Tybulewicz V.L.J. Perinatal lethality and blocked B cell development in mice lacking the tyrosine kinase Syk. Nature. 378:1995;298-302.
-
(1995)
Nature
, vol.378
, pp. 298-302
-
-
Turner, M.1
Mee, P.J.2
Costello, P.S.3
Williams, O.4
Price, A.A.5
Duddy, L.P.6
Furlong, M.T.7
Geahlen, R.L.8
Tybulewicz, V.L.J.9
-
56
-
-
0028783322
-
Syk tyrosine kinase required for mouse viability and B cell development
-
Cheng A.M., Rowley B., Pao W., Hayday A., Bolen J.B., Pawson T. Syk tyrosine kinase required for mouse viability and B cell development. Nature. 378:1995;303-306.
-
(1995)
Nature
, vol.378
, pp. 303-306
-
-
Cheng, A.M.1
Rowley, B.2
Pao, W.3
Hayday, A.4
Bolen, J.B.5
Pawson, T.6
-
58
-
-
0029788103
-
Differential intrinsic enzymatic activity of Syk and ZAP-70 protein tyrosine kinases
-
Latour S., Chow L.M.L., Veillette A. Differential intrinsic enzymatic activity of Syk and ZAP-70 protein tyrosine kinases. J Biol Chem. 271:1996;22782-22790.
-
(1996)
J Biol Chem
, vol.271
, pp. 22782-22790
-
-
Latour, S.1
Chow, L.M.L.2
Veillette, A.3
-
59
-
-
0029952988
-
The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling
-
Chu D., Spits H., Peyron J-F, Rowley R.B., Bolen J.B., Weiss A. The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling. EMBO J. 15:1996;6251-6261.
-
(1996)
EMBO J
, vol.15
, pp. 6251-6261
-
-
Chu, D.1
Spits, H.2
Peyron, J.-F.3
Rowley, R.B.4
Bolen, J.B.5
Weiss, A.6
-
60
-
-
13344270890
-
Altered T cell development in mice lacking Itk
-
Liao X.C., Littman D.R. Altered T cell development in mice lacking Itk. Immunity. 3:1995;757-769.
-
(1995)
Immunity
, vol.3
, pp. 757-769
-
-
Liao, X.C.1
Littman, D.R.2
-
61
-
-
0028183398
-
Bruton's tyrosine kinase is a key regulator in B cell development
-
Rawlings D.J., Witte O.N. Bruton's tyrosine kinase is a key regulator in B cell development. Immunol Rev. 138:1994;105-119.
-
(1994)
Immunol Rev
, vol.138
, pp. 105-119
-
-
Rawlings, D.J.1
Witte, O.N.2
-
62
-
-
0031457622
-
Signaling though scaffold, anchoring, and adaptor proteins
-
Pawson T., Scott J.D. Signaling though scaffold, anchoring, and adaptor proteins. Science. 278:1997;2075-2080.
-
(1997)
Science
, vol.278
, pp. 2075-2080
-
-
Pawson, T.1
Scott, J.D.2
-
63
-
-
0032212728
-
LAT is required for TCR-edmiated activation of PLC-g1 and the ras pathway
-
Finco T.S., Kadlecek T., Zhang W., Samelson L.E., Weiss A. LAT is required for TCR-edmiated activation of PLC-g1 and the ras pathway. Immunity. 9:1998;617-626.
-
(1998)
Immunity
, vol.9
, pp. 617-626
-
-
Finco, T.S.1
Kadlecek, T.2
Zhang, W.3
Samelson, L.E.4
Weiss, A.5
-
64
-
-
0028928422
-
Molecular cloning of SLP-76, a 76 kDa tyrosine phosphoprotein associated with Grb2 in T cells
-
Jackman J.K., Motto D.G., Sun Q., Tanemoto M., Turck C.W., Peltz G.A., Koretzky G.A., Findell P.R. Molecular cloning of SLP-76, a 76 kDa tyrosine phosphoprotein associated with Grb2 in T cells. J Biol Chem. 269:1995;7029-7032.
-
(1995)
J Biol Chem
, vol.269
, pp. 7029-7032
-
-
Jackman, J.K.1
Motto, D.G.2
Sun, Q.3
Tanemoto, M.4
Turck, C.W.5
Peltz, G.A.6
Koretzky, G.A.7
Findell, P.R.8
-
66
-
-
0030602798
-
The MAP kinase pathway controls differentiaton from double-negative to double positive thymocyte
-
Crompton T., Gilmour K.C., Owen M.J. The MAP kinase pathway controls differentiaton from double-negative to double positive thymocyte. Cell. 86:1996;243-251.
-
(1996)
Cell
, vol.86
, pp. 243-251
-
-
Crompton, T.1
Gilmour, K.C.2
Owen, M.J.3
-
67
-
-
0028985017
-
Involvement of p21ras distinguishes positive and negative selection in thymocytes
-
Swan K.A., Alberola-IIa J., Gross J.A., Appleby M.W., Forbush K.A., Thomas J.F., Perlmutter R.M. Involvement of p21ras distinguishes positive and negative selection in thymocytes. EMBO J. 14:1995;276-285.
-
(1995)
EMBO J
, vol.14
, pp. 276-285
-
-
Swan, K.A.1
Alberola J. II2
Gross, J.A.3
Appleby, M.W.4
Forbush, K.A.5
Thomas, J.F.6
Perlmutter, R.M.7
-
68
-
-
0030002904
-
Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor interleukin 2 production
-
Motto D.G., Ross S.E., Wu J., Hendricks-Taylor L.R., Koretzky G.A. Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor interleukin 2 production. J Exp Med. 183:1996;1937-1943.
-
(1996)
J Exp Med
, vol.183
, pp. 1937-1943
-
-
Motto, D.G.1
Ross, S.E.2
Wu, J.3
Hendricks-Taylor, L.R.4
Koretzky, G.A.5
-
69
-
-
0000082758
-
Phosphorylation of SLP76 by the ZAP-70 protein tyrosine kinase is required for T cell receptor function
-
Wardenburg J.B., Fu C., Jackman J.K., Flotow H., Wilkinson S.E., Williams D.H., Johnson R., Kong G., Chan A.C., Findell P. Phosphorylation of SLP76 by the ZAP-70 protein tyrosine kinase is required for T cell receptor function. J Biol Chem. 271:1996;19641-19644.
-
(1996)
J Biol Chem
, vol.271
, pp. 19641-19644
-
-
Wardenburg, J.B.1
Fu, C.2
Jackman, J.K.3
Flotow, H.4
Wilkinson, S.E.5
Williams, D.H.6
Johnson, R.7
Kong, G.8
Chan, A.C.9
Findell, P.10
-
70
-
-
0032541062
-
Uncoupling of nonreceptor tyrosine kinases from PLC-g1 in an SLP-76-deficient T cell
-
Yablonski D., Kuhne M.R., Kadlecek T., Weiss A. Uncoupling of nonreceptor tyrosine kinases from PLC-g1 in an SLP-76-deficient T cell. Science. 281:1998;413-416.
-
(1998)
Science
, vol.281
, pp. 413-416
-
-
Yablonski, D.1
Kuhne, M.R.2
Kadlecek, T.3
Weiss, A.4
-
71
-
-
0032540906
-
Requirment for the leukocyte-specific adapter protein SLP-76 for normal T cell development
-
Clements J.L., Yang B., Ross-Barta S.E., Eliason S.L., Hrstka R.F., Williamson R.A., Koretzky G.A. Requirment for the leukocyte-specific adapter protein SLP-76 for normal T cell development. Science. 281:1998;416-419.
-
(1998)
Science
, vol.281
, pp. 416-419
-
-
Clements, J.L.1
Yang, B.2
Ross-Barta, S.E.3
Eliason, S.L.4
Hrstka, R.F.5
Williamson, R.A.6
Koretzky, G.A.7
-
72
-
-
0032563256
-
Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76
-
Pivniouk V., Tsitsikov E., Swinton P., Rathbun G., Alt F.W., Geha R.S. Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell. 94:1998;229-238.
-
(1998)
Cell
, vol.94
, pp. 229-238
-
-
Pivniouk, V.1
Tsitsikov, E.2
Swinton, P.3
Rathbun, G.4
Alt, F.W.5
Geha, R.S.6
-
73
-
-
0028999988
-
A functional T-cell receptor signaling pathway is required for p95 vav activity
-
Wu J., Katzav S., Weiss A. A functional T-cell receptor signaling pathway is required for p95 vav activity. Mol Cell Biol. 15:1995;4337-4346.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 4337-4346
-
-
Wu, J.1
Katzav, S.2
Weiss, A.3
-
74
-
-
0028956337
-
Defective antigen receptor-mediated proliferation of B and T cells in the absence of vav
-
Tarakhovsky A., Turner M., Schaal S., Mee P.J., Duddy L.P., Rajewsky K., Tybulewicz V.L.J. Defective antigen receptor-mediated proliferation of B and T cells in the absence of vav. Nature. 374:1995;467-470.
-
(1995)
Nature
, vol.374
, pp. 467-470
-
-
Tarakhovsky, A.1
Turner, M.2
Schaal, S.3
Mee, P.J.4
Duddy, L.P.5
Rajewsky, K.6
Tybulewicz, V.L.J.7
-
75
-
-
0028915948
-
Defective signaling through the B and T cell antigen receptors in lymphoid cells lacking the vav proto-oncogene
-
Zhang R., Alt F.W., Davidson L., Orkin S.H., Swat W. Defective signaling through the B and T cell antigen receptors in lymphoid cells lacking the vav proto-oncogene. Nature. 374:1995;470-473.
-
(1995)
Nature
, vol.374
, pp. 470-473
-
-
Zhang, R.1
Alt, F.W.2
Davidson, L.3
Orkin, S.H.4
Swat, W.5
-
77
-
-
0030744134
-
Role of phosphatases in lymphocyte activation
-
Neel B.G. Role of phosphatases in lymphocyte activation. Curr Opin Immunol. 9:1997;405-420.
-
(1997)
Curr Opin Immunol
, vol.9
, pp. 405-420
-
-
Neel, B.G.1
-
78
-
-
0029864147
-
+thymocytes, and in B cell maturation
-
+thymocytes, and in B cell maturation. J Exp Med. 183:1996;1707-1718.
-
(1996)
J Exp Med
, vol.183
, pp. 1707-1718
-
-
Blyth, K.F.1
Conroy, L.A.2
Howlett, S.3
Smith, A.J.H.4
May, J.5
Alexander, D.R.6
Holmes, N.7
-
79
-
-
0027296521
-
Normal B cell development but impaired T cell maturation in CD45-exon 6 protein tyrosine phosphatase deficient mice
-
Kishihara K., Penninger J., Wallace V.A., Kundig T.M., Kawai K., Wakeham A., Timms E., Pfeffer K., Ohashi P.S., Thomas M.L., Furlonger C., Paige C.J., Mak T.W. Normal B cell development but impaired T cell maturation in CD45-exon 6 protein tyrosine phosphatase deficient mice. Cell. 74:1993;143-156.
-
(1993)
Cell
, vol.74
, pp. 143-156
-
-
Kishihara, K.1
Penninger, J.2
Wallace, V.A.3
Kundig, T.M.4
Kawai, K.5
Wakeham, A.6
Timms, E.7
Pfeffer, K.8
Ohashi, P.S.9
Thomas, M.L.10
Furlonger, C.11
Paige, C.J.12
Mak, T.W.13
-
80
-
-
0031570545
-
Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-zeta, and ZAP-70
-
Stone J.D., Conroy L.A., Byth K.F., Hederer R.A., Howlett S., Takemoto Y., Holmes N., Alexander D.R. Aberrant TCR-mediated signaling in CD45-null thymocytes involves dysfunctional regulation of Lck, Fyn, TCR-zeta, and ZAP-70. J Immunol. 158:1997;5773-5782.
-
(1997)
J Immunol
, vol.158
, pp. 5773-5782
-
-
Stone, J.D.1
Conroy, L.A.2
Byth, K.F.3
Hederer, R.A.4
Howlett, S.5
Takemoto, Y.6
Holmes, N.7
Alexander, D.R.8
-
81
-
-
0029787216
-
Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase
-
Pani G., Fischer K-D, Mlinaric-Rascan I., Siminovitch K.A. Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase. J Exp Med. 184:1996;839-852.
-
(1996)
J Exp Med
, vol.184
, pp. 839-852
-
-
Pani, G.1
Fischer, K.-D.2
Mlinaric-Rascan, I.3
Siminovitch, K.A.4
-
82
-
-
0029904138
-
Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling
-
Plas D.R., Johnson R., Pingel J.T., Matthews R.J., Dalton M., Roy G., Chan A.C., Thomas M. Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling. Science. 272:1996;1173-1176.
-
(1996)
Science
, vol.272
, pp. 1173-1176
-
-
Plas, D.R.1
Johnson, R.2
Pingel, J.T.3
Matthews, R.J.4
Dalton, M.5
Roy, G.6
Chan, A.C.7
Thomas, M.8
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