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Volumn 15, Issue 22, 1996, Pages 6251-6261

The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling

Author keywords

CD45; Syk; TCR; Tyrosine kinase; ZAP 70

Indexed keywords

CD45 ANTIGEN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR;

EID: 0029952988     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb01015.x     Document Type: Article
Times cited : (113)

References (62)
  • 1
    • 0029070579 scopus 로고
    • The SH2 domains of Src family kinases associate with Syk
    • Aoki, Y., Kim, Y.-T., Stillwell, R., Kim, T.J. and Pillai, S. (1995) The SH2 domains of Src family kinases associate with Syk. J. Biol. Chem., 270, 15658-15663.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15658-15663
    • Aoki, Y.1    Kim, Y.-T.2    Stillwell, R.3    Kim, T.J.4    Pillai, S.5
  • 4
    • 0029063151 scopus 로고
    • Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance
    • Bu, J.-Y., Shaw, A.S. and Chan, A.C. (1995) Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance. Proc. Natl Acad. Sci. USA, 92, 5106-5110.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 5106-5110
    • Bu, J.-Y.1    Shaw, A.S.2    Chan, A.C.3
  • 5
    • 0025832286 scopus 로고
    • Biochemical identification of a direct physical interaction between the CD4:p56lck and Ti(TCR)/CD3 complexes
    • Burgess, K.E., Odysseos, A.D., Zalvan, C., Drucker, B., Anderson, P., Schlossman, S.F. and Rudd, C.E. (1991) Biochemical identification of a direct physical interaction between the CD4:p56lck and Ti(TCR)/CD3 complexes. Eur. J. Immunol., 21, 1663-1668.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 1663-1668
    • Burgess, K.E.1    Odysseos, A.D.2    Zalvan, C.3    Drucker, B.4    Anderson, P.5    Schlossman, S.F.6    Rudd, C.E.7
  • 6
    • 0028064781 scopus 로고
    • Temporal regulation of non-transmembrane protein tyrosine kinase enzyme activity following T cell antigen receptor engagement
    • Burkhardt, A.L., Stealey, B., Rowley, R.B., Mahajan, S., Prendergast, M., Fargnoli, J. and Bolen, J.B. (1994) Temporal regulation of non-transmembrane protein tyrosine kinase enzyme activity following T cell antigen receptor engagement. J. Biol. Chem., 269, 23642-23647.
    • (1994) J. Biol. Chem. , vol.269 , pp. 23642-23647
    • Burkhardt, A.L.1    Stealey, B.2    Rowley, R.B.3    Mahajan, S.4    Prendergast, M.5    Fargnoli, J.6    Bolen, J.B.7
  • 7
    • 0026483786 scopus 로고
    • ZAP-70: A 70kD protein tyrosine kinase that associates with the TCR ζ chain
    • Chan, A.C., Iwashima, M., Turck, C.W. and Weiss, A. (1992) ZAP-70: a 70kD protein tyrosine kinase that associates with the TCR ζ chain. Cell. 71, 649-662.
    • (1992) Cell , vol.71 , pp. 649-662
    • Chan, A.C.1    Iwashima, M.2    Turck, C.W.3    Weiss, A.4
  • 9
    • 0028216232 scopus 로고
    • Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in T cell antigen receptor signaling
    • Chan, A.C., van Oers, N.S.C., Tran, A., Turka, L., Law, C.-L., Ryan, J.C., Clark, E.A. and Weiss, A. (1994b) Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in T cell antigen receptor signaling. J. Immunol., 152, 4758-1766.
    • (1994) J. Immunol. , vol.152 , pp. 4758-11766
    • Chan, A.C.1    Van Oers, N.S.C.2    Tran, A.3    Turka, L.4    Law, C.-L.5    Ryan, J.C.6    Clark, E.A.7    Weiss, A.8
  • 10
    • 0029071585 scopus 로고
    • Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function
    • Chan, A.C., Dalton, M., Johnson, R., Kong, G.-H., Wang, T., Thoma, R. and Kurosaki, T. (1995) Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function. EMBO J., 14, 2499-2508.
    • (1995) EMBO J. , vol.14 , pp. 2499-2508
    • Chan, A.C.1    Dalton, M.2    Johnson, R.3    Kong, G.-H.4    Wang, T.5    Thoma, R.6    Kurosaki, T.7
  • 11
    • 0028783322 scopus 로고
    • Syk tyrosine kinase required for mouse viability and B-cell development
    • Cheng, A.M., Rowley, B., Pao, W., Hayday, A., Bolen, J.B. and Pawson, T. (1995) Syk tyrosine kinase required for mouse viability and B-cell development. Nature, 378, 303-306.
    • (1995) Nature , vol.378 , pp. 303-306
    • Cheng, A.M.1    Rowley, B.2    Pao, W.3    Hayday, A.4    Bolen, J.B.5    Pawson, T.6
  • 13
    • 0027300619 scopus 로고
    • The when and how of Src regulation
    • Cooper, J.A. and Howell, B. (1993) The when and how of Src regulation. Cell, 73, 1051-1054.
    • (1993) Cell , vol.73 , pp. 1051-1054
    • Cooper, J.A.1    Howell, B.2
  • 15
    • 0028169299 scopus 로고
    • syk through physical association and N-terminal tyrosine phosphorylation
    • syk through physical association and N-terminal tyrosine phosphorylation. Mol. Cell. Biol., 14, 5249-5258.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 5249-5258
    • Couture, C.1
  • 16
    • 0028177590 scopus 로고
    • lck interacts via its src homology 2 domain with the ZAP-70 kinase
    • lck interacts via its src homology 2 domain with the ZAP-70 kinase. J. Exp. Med., 179, 1163-1172.
    • (1994) J. Exp. Med. , vol.179 , pp. 1163-1172
    • Duplay, P.1    Thome, M.2    Hervé, F.3    Acuto, O.4
  • 18
    • 0028292001 scopus 로고
    • Human severe combined immunodeficiency due to a defect in ZAP-70, a T-cell tyrosine kinase
    • Elder, M.E., Lin, D., Clever, J., Cahn, A.C., Hope, T.J., Weiss, A. and Parslow, T.G. (1994) Human severe combined immunodeficiency due to a defect in ZAP-70, a T-cell tyrosine kinase. Science, 264, 1596-1599.
    • (1994) Science , vol.264 , pp. 1596-1599
    • Elder, M.E.1    Lin, D.2    Clever, J.3    Cahn, A.C.4    Hope, T.J.5    Weiss, A.6    Parslow, T.G.7
  • 20
    • 0029087530 scopus 로고
    • Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not thymocytes
    • Gelfand, E.W., Weinberg, K., Mazer, B.D., Kadlecek, T.A. and Weiss, A. (1995) Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not thymocytes. J. Exp. Med., 182, 1057-1066.
    • (1995) J. Exp. Med. , vol.182 , pp. 1057-1066
    • Gelfand, E.W.1    Weinberg, K.2    Mazer, B.D.3    Kadlecek, T.A.4    Weiss, A.5
  • 21
    • 0023429078 scopus 로고
    • Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor
    • Goldsmith, M.A. and Weiss, A. (1987) Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor. Proc. Natl Acad. Sci. USA, 84, 6879-6883.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 6879-6883
    • Goldsmith, M.A.1    Weiss, A.2
  • 22
  • 23
    • 0028582185 scopus 로고
    • Crystal structure of the tyrosine kinase domain of the human insulin receptor
    • Hubbard, S.R., Wei, L., Ellis, L. and Hendrickson, W.A. (1994) Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature, 372, 746-754.
    • (1994) Nature , vol.372 , pp. 746-754
    • Hubbard, S.R.1    Wei, L.2    Ellis, L.3    Hendrickson, W.A.4
  • 24
    • 0027410485 scopus 로고
    • Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases
    • Hurley, T.R., Hyman, R. and Sefton, B.M. (1993) Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases. Mol. Cell. Biol., 13, 1651-1656.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1651-1656
    • Hurley, T.R.1    Hyman, R.2    Sefton, B.M.3
  • 25
    • 0028209548 scopus 로고
    • Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases
    • Iwashima, M., Irving, B.A., van Oers, N.S.C., Chan, A.C. and Weiss, A. (1994) Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science, 263, 1136-1139.
    • (1994) Science , vol.263 , pp. 1136-1139
    • Iwashima, M.1    Irving, B.A.2    Van Oers, N.S.C.3    Chan, A.C.4    Weiss, A.5
  • 26
    • 0025898888 scopus 로고
    • Regulation of B cell antigen receptor signal transduction and phosphorylation by CD45
    • Justement, L.B., Campbell, K.S., Chien, N.C. and Cambier, J.C. (1991) Regulation of B cell antigen receptor signal transduction and phosphorylation by CD45. Science, 252, 1839-1842.
    • (1991) Science , vol.252 , pp. 1839-1842
    • Justement, L.B.1    Campbell, K.S.2    Chien, N.C.3    Cambier, J.C.4
  • 28
    • 0027296521 scopus 로고
    • Normal B lymphocyte development but impaired T cell maturation in CD45-Exon 6 protein tyrosine phosphatase-deficient mice
    • Kishihara, K. et al. (1993) Normal B lymphocyte development but impaired T cell maturation in CD45-Exon 6 protein tyrosine phosphatase-deficient mice. Cell, 74, 143-156.
    • (1993) Cell , vol.74 , pp. 143-156
    • Kishihara, K.1
  • 29
    • 0027185152 scopus 로고
    • T cell activation by clustered tyrosine kinases
    • Kolanus, W., Romeo, C. and Seed, B. (1993) T cell activation by clustered tyrosine kinases. Cell, 74, 171-183.
    • (1993) Cell , vol.74 , pp. 171-183
    • Kolanus, W.1    Romeo, C.2    Seed, B.3
  • 30
    • 0029076731 scopus 로고
    • Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase
    • Kong, G.-H., Bu, J.-Y., Kurosaki, T., Shaw, A.S. and Chan, A.C. (1995) Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase. Immunity, 2, 485-492.
    • (1995) Immunity , vol.2 , pp. 485-492
    • Kong, G.-H.1    Bu, J.-Y.2    Kurosaki, T.3    Shaw, A.S.4    Chan, A.C.5
  • 31
    • 0025297050 scopus 로고
    • Tyrosine phosphatase CD45 is essential for coupling T cell antigen receptor to the phosphatidylinositol pathway
    • Koretzky, G.A., Picus, J., Thomas, M.L. and Weiss, A. (1990) Tyrosine phosphatase CD45 is essential for coupling T cell antigen receptor to the phosphatidylinositol pathway. Nature, 346, 66-68.
    • (1990) Nature , vol.346 , pp. 66-68
    • Koretzky, G.A.1    Picus, J.2    Thomas, M.L.3    Weiss, A.4
  • 32
    • 0026011310 scopus 로고
    • Tyrosine phosphatase CD45 is required for both T cell antigen receptor and CD2 mediated activation of a protein tyrosine kinase and interleukin 2 production
    • Koretzky, G., Picus, J., Schultz, T. and Weiss, A. (1991) Tyrosine phosphatase CD45 is required for both T cell antigen receptor and CD2 mediated activation of a protein tyrosine kinase and interleukin 2 production. Proc. Natl Acad. Sci. USA, 88, 2037-2041.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 2037-2041
    • Koretzky, G.1    Picus, J.2    Schultz, T.3    Weiss, A.4
  • 33
    • 0000387536 scopus 로고
    • B cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn
    • Law, D.A., Chan, V.W.-F., Datta, S.K. and DeFranco, A.L. (1993) B cell antigen receptor motifs have redundant signalling capabilities and bind the tyrosine kinases PTK72, Lyn and Fyn. Curr. Biol., 3, 645-657.
    • (1993) Curr. Biol. , vol.3 , pp. 645-657
    • Law, D.A.1    Chan, V.W.-F.2    Datta, S.K.3    DeFranco, A.L.4
  • 36
    • 0027475743 scopus 로고
    • Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor
    • McFarland, E.D.C., Hurley, T.R., Pingel, J.T., Sefton, B.M., Shaw, A. and Thomas, M.L. (1993) Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor. Proc. Natl Acad. Sci. USA, 90, 1402-1406.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 1402-1406
    • McFarland, E.D.C.1    Hurley, T.R.2    Pingel, J.T.3    Sefton, B.M.4    Shaw, A.5    Thomas, M.L.6
  • 37
    • 0024991898 scopus 로고
    • pEF-BOS, a powerful mammalian expression vector
    • Mizushima, S. and Nagata, S. (1990) pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res., 18, 5322.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 5322
    • Mizushima, S.1    Nagata, S.2
  • 38
    • 0026522204 scopus 로고
    • Profound block in thymocyte development in mice lacking p56lck
    • Molina, T.J. et al. (1992) Profound block in thymocyte development in mice lacking p56lck. Nature, 357, 161-164.
    • (1992) Nature , vol.357 , pp. 161-164
    • Molina, T.J.1
  • 39
    • 0000072679 scopus 로고
    • Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase
    • Mustelin, T., Coggeshall, K.M. and Altman, A. (1989) Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase. Proc. Natl Acad. Sci. USA, 86, 6302-6306.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 6302-6306
    • Mustelin, T.1    Coggeshall, K.M.2    Altman, A.3
  • 42
    • 0029031806 scopus 로고
    • Binding of ZAP-70 to phosphorylated T-cell receptor ζ and η enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins
    • Neumeister, E.N., Zhu, Y., Richard, S., Terhorst, C., Chan, A.C. and Shaw, A.S. (1995) Binding of ZAP-70 to phosphorylated T-cell receptor ζ and η enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins. Mol. Cell. Biol., 15, 3171-3178.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3171-3178
    • Neumeister, E.N.1    Zhu, Y.2    Richard, S.3    Terhorst, C.4    Chan, A.C.5    Shaw, A.S.6
  • 44
    • 0026330922 scopus 로고
    • The CD45 protein tyrosine phosphatase is required for the completion of the activation program leading to lymphokine production in the Jurkat human T cell line
    • Peyron, J.-F., Verma, S., Malefyt, R., Sancho, J., Terhorst, C. and Spits, H. (1991) The CD45 protein tyrosine phosphatase is required for the completion of the activation program leading to lymphokine production in the Jurkat human T cell line. Int. Immunol., 3, 1357-1366.
    • (1991) Int. Immunol. , vol.3 , pp. 1357-1366
    • Peyron, J.-F.1    Verma, S.2    Malefyt, R.3    Sancho, J.4    Terhorst, C.5    Spits, H.6
  • 45
    • 0024416009 scopus 로고
    • Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation
    • Pingel, J.T. and Thomas, M.L. (1989) Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation. Cell, 58, 1055-1065.
    • (1989) Cell , vol.58 , pp. 1055-1065
    • Pingel, J.T.1    Thomas, M.L.2
  • 46
    • 0027457925 scopus 로고
    • Multiple components of the T cell antigen receptor complex become tyrosine-phosphorylated upon activation
    • Qian, D., Griswold-Prenner, I., Rosner, M.R. and Fitch, F.W. (1993) Multiple components of the T cell antigen receptor complex become tyrosine-phosphorylated upon activation. J. Biol. Chem., 268, 4488-4493.
    • (1993) J. Biol. Chem. , vol.268 , pp. 4488-4493
    • Qian, D.1    Griswold-Prenner, I.2    Rosner, M.R.3    Fitch, F.W.4
  • 47
    • 0029068171 scopus 로고
    • Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Igα/Igβ immunoreceptor tyrosine activation motif binding and autophosphorylation
    • Rowley, R.B., Burkhardt, A.L., Chao, H.-G., Matsueda, G.R. and Bolen, J.B. (1995) Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Igα/Igβ immunoreceptor tyrosine activation motif binding and autophosphorylation. J. Biol. Chem., 270, 11590-11594.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11590-11594
    • Rowley, R.B.1    Burkhardt, A.L.2    Chao, H.-G.3    Matsueda, G.R.4    Bolen, J.B.5
  • 48
    • 0025325392 scopus 로고
    • Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor
    • Samelson, L.E., Phillips, A.F., Luong, E.T. and Klausner, R.D. (1990) Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor. Proc. Natl Acad. Sci. USA, 87, 4358-4362.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 4358-4362
    • Samelson, L.E.1    Phillips, A.F.2    Luong, E.T.3    Klausner, R.D.4
  • 49
    • 0028060150 scopus 로고
    • Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement
    • Saouaf, S.J., Mahajan, S., Rowley, R.B., Kut, S.A., Fargnoli, J., Burkhardt, A.L., Tsukada, S., Witte, O.N. and Bolen, J.B. (1994) Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement. Proc. Natl Acad. Sci. USA, 91, 9524-9528.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 9524-9528
    • Saouaf, S.J.1    Mahajan, S.2    Rowley, R.B.3    Kut, S.A.4    Fargnoli, J.5    Burkhardt, A.L.6    Tsukada, S.7    Witte, O.N.8    Bolen, J.B.9
  • 50
    • 0027050564 scopus 로고
    • fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influx
    • fyn couples the T cell antigen receptor to pathways of diacylglycerol production, protein kinase C activation and calcium influx. EMBO J., 11, 4887-4897.
    • (1992) EMBO J. , vol.11 , pp. 4887-4897
    • Shiroo, M.1    Goff, L.2    Biffen, M.3    Shivnan, E.4    Alexander, D.5
  • 51
    • 0028905060 scopus 로고
    • Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE
    • Shiue, L., Zoller, M.J. and Brugge, J.S. (1995) Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE. J. Biol. Chem., 270, 10498-10502.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10498-10502
    • Shiue, L.1    Zoller, M.J.2    Brugge, J.S.3
  • 52
    • 0027389272 scopus 로고
    • CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck
    • Sieh, M., Bolen, J.B. and Weiss, A. (1993) CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck. EMBO J., 12, 315-322.
    • (1993) EMBO J. , vol.12 , pp. 315-322
    • Sieh, M.1    Bolen, J.B.2    Weiss, A.3
  • 53
    • 0026612411 scopus 로고
    • fyn mutant mice display differential signaling in thymocytes and peripheral T cells
    • fyn mutant mice display differential signaling in thymocytes and peripheral T cells. Cell, 70, 741-750.
    • (1992) Cell , vol.70 , pp. 741-750
    • Stein, P.L.1    Lee, H.-M.2    Rich, S.3    Soriano, P.4
  • 54
    • 0026705903 scopus 로고
    • Genetic evidence for the involvement of the Lck tyrosine kinase in signal transduction through the T cell antigen receptor
    • Straus, D. and Weiss, A. (1992) Genetic evidence for the involvement of the Lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell, 70, 585-593.
    • (1992) Cell , vol.70 , pp. 585-593
    • Straus, D.1    Weiss, A.2
  • 57
    • 0028877062 scopus 로고
    • The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-ζ subunit
    • van Oers, N.S.C., von Bochmer, H. and Weiss, A. (1995) The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-ζ subunit. J. Exp. Med., 182, 1585-1590.
    • (1995) J. Exp. Med. , vol.182 , pp. 1585-1590
    • Van Oers, N.S.C.1    Von Bochmer, H.2    Weiss, A.3
  • 58
    • 0029866039 scopus 로고    scopus 로고
    • Lck regulates the tyrosine phosphorylation of the TCR subunits and ZAP-70 in murine thymocytes
    • van Oers, N.S.C., Killeen, N. and Weiss, A. (1996) Lck regulates the tyrosine phosphorylation of the TCR subunits and ZAP-70 in murine thymocytes. J. Exp. Med., 183, 1053-1062.
    • (1996) J. Exp. Med. , vol.183 , pp. 1053-1062
    • Van Oers, N.S.C.1    Killeen, N.2    Weiss, A.3
  • 60
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss, A. and Littman, D.R. (1994) Signal transduction by lymphocyte antigen receptors. Cell, 76, 263-274.
    • (1994) Cell , vol.76 , pp. 263-274
    • Weiss, A.1    Littman, D.R.2
  • 61
    • 0021678703 scopus 로고
    • Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line
    • Weiss, A. and Stobo, J.D. (1984) Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. J. Exp. Med., 160, 1284-1299.
    • (1984) J. Exp. Med. , vol.160 , pp. 1284-1299
    • Weiss, A.1    Stobo, J.D.2
  • 62
    • 0021245601 scopus 로고
    • The role of T3 surface molecules in the activation of human T cells: A two stimulus requirement for IL-2 production reflects events occurring at a pretranslational level
    • Weiss, A., Wiskocil, R. and Stobo, J.D. (1984) The role of T3 surface molecules in the activation of human T cells: a two stimulus requirement for IL-2 production reflects events occurring at a pretranslational level. J. Immunol., 133, 123-128.
    • (1984) J. Immunol. , vol.133 , pp. 123-128
    • Weiss, A.1    Wiskocil, R.2    Stobo, J.D.3


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