Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes

Biochemical and Biophysical Research Communications

Volumn 272, Issue 2, 2000, Pages 596-602

  Sujay Subbayya, I N ^a   Sukumaran, Suja ^a   Shivashankar, K ^a   Balaram, Hemalatha ^a  

^a JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

Chimera; Drug target; HGPRT; Plasmodium falciparum; Substrate specificity

Indexed keywords

AMINO ACID; CHIMERIC PROTEIN; ENZYME; GUANINE; HYPOXANTHINE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INOSINE PHOSPHATE; PHOSPHORIBOSYL PYROPHOSPHATE; PURINE; PURINE DERIVATIVE; RIBOSE PHOSPHATE; XANTHINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; GENETIC ENGINEERING; HUMAN; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

FELIS CATUS; PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0003012497     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.2816     Document Type: Article

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