Crystal structures of the Toxoplasma gondii hypoxanthine-guanine phosphoribosyltransferase-GMP and -IMP complexes: Comparison of purine binding interactions with the XMP complex

Biochemistry

Volumn 38, Issue 44, 1999, Pages 14485-14494

  Héroux, Annie ^a   White, E Lucile ^a   Ross, Larry J ^a   Borhani, David W ^a  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE PHOSPHATE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INOSINE PHOSPHATE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; TOXOPLASMA GONDII;

5'-GUANYLIC ACID; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INOSINE MONOPHOSPHATE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN STRUCTURE, QUATERNARY; RECOMBINANT PROTEINS; RIBONUCLEOTIDES; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; TOXOPLASMA;

TOXOPLASMA GONDII;

EID: 0033517848     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990507q     Document Type: Article

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