Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus

Biochemistry

Volumn 35, Issue 22, 1996, Pages 7032-7040

  Somoza, John R ^a   Chin, Marian S ^a   Focia, Pamela J ^a   Wang, Ching C ^a   Fletterick, Robert J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE DERIVATIVE; HYPOXANTHINE DERIVATIVE; PHOSPHORIBOSYLTRANSFERASE; XANTHINE DERIVATIVE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME SPECIFICITY; ENZYME SUBSTRATE; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE; PRIORITY JOURNAL; TARGET CELL; TRICHOMONAS FOETUS; TRICHOMONIASIS; X RAY CRYSTALLOGRAPHY;

5'-GUANYLIC ACID; AMINO ACID SEQUENCE; ANIMALS; ANTIPROTOZOAL AGENTS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; HUMANS; HYDROGEN BONDING; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PENTOSYLTRANSFERASES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTOZOAN PROTEINS; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; TRITRICHOMONAS FOETUS;

PROTOZOA; TRICHOMONAS; TRITRICHOMONAS FOETUS;

EID: 0029898439     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi953072p     Document Type: Article

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