Understanding substrate specificity in human and parasite phosphoribosyltransferases through calculation and experiment

Biochemistry

Volumn 38, Issue 32, 1999, Pages 10298-10306

  Pitera, Jed W ^a   Munagala, Narsimha R ^a   Wang, Ching C ^a   Kollman, Peter A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MUTANT PROTEIN; PHOSPHORIBOSYLTRANSFERASE; XANTHINE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME SPECIFICITY; HUMAN; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; TRICHOMONAS FOETUS;

5'-GUANYLIC ACID; ANIMALS; COMPUTER SIMULATION; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PENTOSYLTRANSFERASES; PROTEIN CONFORMATION; RIBONUCLEOTIDES; SOFTWARE; SUBSTRATE SPECIFICITY; THERMODYNAMICS; TRITRICHOMONAS FOETUS;

EID: 0033543150     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi990250w     Document Type: Article

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