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Volumn 5, Issue 12, 2004, Pages 952-962

Receptor trafficking and synaptic plasticity

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; AMPA RECEPTOR; GLUTAMATE RECEPTOR; GLUTAMIC ACID; KAINIC ACID RECEPTOR; NEUROTRANSMITTER RECEPTOR;

EID: 9944252377     PISSN: 1471003X     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrn1556     Document Type: Review
Times cited : (871)

References (132)
  • 1
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • Bliss, T. V. & Collingridge, G. L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361, 31-39 (1993).
    • (1993) Nature , vol.361 , pp. 31-39
    • Bliss, T.V.1    Collingridge, G.L.2
  • 2
    • 0032565873 scopus 로고    scopus 로고
    • Modulation of AMPA receptor unitary conductance by synaptic activity
    • Benke, T. A., Luthi, A., Isaac, J. T. & Collingridge, G. L. Modulation of AMPA receptor unitary conductance by synaptic activity. Nature 393, 793-797 (1998).
    • (1998) Nature , vol.393 , pp. 793-797
    • Benke, T.A.1    Luthi, A.2    Isaac, J.T.3    Collingridge, G.L.4
  • 3
    • 0034713303 scopus 로고    scopus 로고
    • Synaptic activity at calcium-permeable AMPA receptors induces a switch in receptor subtype
    • Liu, S. Q. & Cull-Candy, S. G. Synaptic activity at calcium-permeable AMPA receptors induces a switch in receptor subtype. Nature 405, 454-458 (2000). This was the first research to show that synaptic activity can rapidly regulate the subunit composition of AMPARs at synapses.
    • (2000) Nature , vol.405 , pp. 454-458
    • Liu, S.Q.1    Cull-Candy, S.G.2
  • 4
    • 2542609999 scopus 로고    scopus 로고
    • Multiple, developmentally regulated expression mechanisms of long-term potentiation at CA1 synapses
    • Palmer, M. J., Isaac, J. T. & Collingridge, G. L. Multiple, developmentally regulated expression mechanisms of long-term potentiation at CA1 synapses. J. Neurosci. 24, 4903-4911 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 4903-4911
    • Palmer, M.J.1    Isaac, J.T.2    Collingridge, G.L.3
  • 5
    • 0036305484 scopus 로고    scopus 로고
    • AMPA receptor trafficking and synaptic plasticity
    • Malinow, R. & Malenka, R. C. AMPA receptor trafficking and synaptic plasticity. Annu. Rev. Neurosci. 25, 103-126 (2002).
    • (2002) Annu. Rev. Neurosci. , vol.25 , pp. 103-126
    • Malinow, R.1    Malenka, R.C.2
  • 6
    • 0033213634 scopus 로고    scopus 로고
    • Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction
    • Luthi, A. et al. Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction. Neuron 24, 389-399 (1999). The first evidence that LTD involves receptor internalization, and that this uses a mechanism involving the NSF-sensitive pool of AMPARs.
    • (1999) Neuron , vol.24 , pp. 389-399
    • Luthi, A.1
  • 7
    • 0030572753 scopus 로고    scopus 로고
    • Localization of the glutamate receptor subunit GluR1 on the surface of living and within cultured hippocampal neurons
    • Richmond, S. A. et al. Localization of the glutamate receptor subunit GluR1 on the surface of living and within cultured hippocampal neurons. Neuroscience 75, 69-82 (1996). This work introduced the use of antibodies for live cell imaging of glutamate receptors and showed marked differences in the surface and intracellular distributions of AMPARs at synapses.
    • (1996) Neuroscience , vol.75 , pp. 69-82
    • Richmond, S.A.1
  • 8
    • 0141918783 scopus 로고    scopus 로고
    • AMPA receptor trafficking at excitatory synapses
    • Bredt, D. S. & Nicoll, R. A. AMPA receptor trafficking at excitatory synapses. Neuron 40, 361-379 (2003).
    • (2003) Neuron , vol.40 , pp. 361-379
    • Bredt, D.S.1    Nicoll, R.A.2
  • 9
    • 0033546052 scopus 로고    scopus 로고
    • Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation
    • Shi, S. H. et al. Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation. Science 284, 1811-1816 (1999).
    • (1999) Science , vol.284 , pp. 1811-1816
    • Shi, S.H.1
  • 10
    • 0034708587 scopus 로고    scopus 로고
    • Driving AMPA receptors into synapses by LTP and CaMKII: Requirement for GluR1 and PDZ domain interaction
    • Hayashi, Y. et al. Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science 287, 2262-2267 (2000). The first direct electrophysiological evidence that AMPARs are incorporated into synapses during LTP.
    • (2000) Science , vol.287 , pp. 2262-2267
    • Hayashi, Y.1
  • 11
    • 2642552398 scopus 로고    scopus 로고
    • Removal of AMPA receptors (AMPARs) from synapses is preceded by transient endocytosis of extrasynaptic AMPARs
    • Ashby, M. C. et al. Removal of AMPA receptors (AMPARs) from synapses is preceded by transient endocytosis of extrasynaptic AMPARs. J. Neurosci. 24, 5172-5176 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 5172-5176
    • Ashby, M.C.1
  • 12
    • 0033696622 scopus 로고    scopus 로고
    • Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD
    • Beattie, E. C. et al. Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD. Nature Neurosci. 3, 1291-1300 (2000). This paper reports that NMDA stimulation of cultured hippocampal neurons results in a rapid dynamin-dependent endocytosis of AMPARs and depression of miniature excitatory postsynaptic currents (mEPSCs) using mechanisms similar to LTD in the CA1 region of hippocampal slices.
    • (2000) Nature Neurosci. , vol.3 , pp. 1291-1300
    • Beattie, E.C.1
  • 14
    • 0035132869 scopus 로고    scopus 로고
    • Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons
    • Lu, W. et al. Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons. Neuron 29, 243-254 (2001).
    • (2001) Neuron , vol.29 , pp. 243-254
    • Lu, W.1
  • 15
    • 0034788303 scopus 로고    scopus 로고
    • Transient synaptic activation of NMDA receptors leads to the insertion of native AMPA receptors at hippocampal neuronal plasma membranes
    • Pickard, L. et al. Transient synaptic activation of NMDA receptors leads to the insertion of native AMPA receptors at hippocampal neuronal plasma membranes. Neuropharmacology 41, 700-713 (2001). References 14 & 15 were the first papers to show that native AMPARs can be inserted into synapses during LTP.
    • (2001) Neuropharmacology , vol.41 , pp. 700-713
    • Pickard, L.1
  • 16
    • 0035708880 scopus 로고    scopus 로고
    • Internalization of ionotropic glutamate receptors in response to mGluR activation
    • Snyder, E. M. et al. Internalization of ionotropic glutamate receptors in response to mGluR activation. Nature Neurosci. 4, 1079-1085 (2001).
    • (2001) Nature Neurosci. , vol.4 , pp. 1079-1085
    • Snyder, E.M.1
  • 17
    • 0034788373 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor activation causes a rapid redistribution of AMPA receptors
    • Xiao, M. Y., Zhou, Q. & Nicoll, R. A. Metabotropic glutamate receptor activation causes a rapid redistribution of AMPA receptors. Neuropharmacology 41, 664-671 (2001).
    • (2001) Neuropharmacology , vol.41 , pp. 664-671
    • Xiao, M.Y.1    Zhou, Q.2    Nicoll, R.A.3
  • 18
    • 0037030721 scopus 로고    scopus 로고
    • Regulation of AMPA receptor lateral movements
    • Borgdorff, A. J. & Choquet, D. Regulation of AMPA receptor lateral movements. Nature 417, 649-653 (2002). The first direct evidence that lateral diffusion of AMPARs in the plasma membrane might be an important aspect of synaptic plasticity.
    • (2002) Nature , vol.417 , pp. 649-653
    • Borgdorff, A.J.1    Choquet, D.2
  • 19
    • 0141737070 scopus 로고    scopus 로고
    • Direct imaging of lateral movements of AMPA receptors inside synapses
    • Tardin, C., Cognet, L., Bats, C., Lounis, B. & Choquet, D. Direct imaging of lateral movements of AMPA receptors inside synapses. EMBO J. 22, 4656-4665 (2003).
    • (2003) EMBO J. , vol.22 , pp. 4656-4665
    • Tardin, C.1    Cognet, L.2    Bats, C.3    Lounis, B.4    Choquet, D.5
  • 20
    • 0034869177 scopus 로고    scopus 로고
    • Subunit-specific temporal and spatial patterns of AMPA receptor exocytosis in hippocampal neurons
    • Passafaro, M., Piech, V. & Sheng, M. Subunit-specific temporal and spatial patterns of AMPA receptor exocytosis in hippocampal neurons. Nature Neurosci. 4, 917-926 (2001).
    • (2001) Nature Neurosci. , vol.4 , pp. 917-926
    • Passafaro, M.1    Piech, V.2    Sheng, M.3
  • 21
    • 0037168123 scopus 로고    scopus 로고
    • Dynamics and regulation of clathrin coats at specialized endocytic zones of dendrites and spines
    • Blanpied, T. A., Scott, D. B. & Ehlers, M. D. Dynamics and regulation of clathrin coats at specialized endocytic zones of dendrites and spines. Neuron 36, 435-449 (2002).
    • (2002) Neuron , vol.36 , pp. 435-449
    • Blanpied, T.A.1    Scott, D.B.2    Ehlers, M.D.3
  • 22
    • 0037312605 scopus 로고    scopus 로고
    • PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity
    • Esteban, J. A. et al. PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity. Nature Neurosci. 6, 136-143 (2003).
    • (2003) Nature Neurosci. , vol.6 , pp. 136-143
    • Esteban, J.A.1
  • 23
    • 0037762556 scopus 로고    scopus 로고
    • Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons
    • Man, H. Y. et al. Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons. Neuron 38, 611-624 (2003).
    • (2003) Neuron , vol.38 , pp. 611-624
    • Man, H.Y.1
  • 24
    • 0032127472 scopus 로고    scopus 로고
    • NSF binding to GluR2 regulates synaptic transmission
    • Nishimune, A. et al. NSF binding to GluR2 regulates synaptic transmission. Neuron 21, 87-97 (1998). The first evidence that there is a rapidly recycling pool of AMPARs at synapses and that this is regulated by the direct interaction between NSF and the GluR2 subunit.
    • (1998) Neuron , vol.21 , pp. 87-97
    • Nishimune, A.1
  • 25
    • 0032125884 scopus 로고    scopus 로고
    • The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and α- and β-SNAPs
    • Osten, P. et al. The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and α- and β-SNAPs. Neuron 21, 99-110 (1998).
    • (1998) Neuron , vol.21 , pp. 99-110
    • Osten, P.1
  • 26
    • 0032536033 scopus 로고    scopus 로고
    • Postsynaptic membrane fusion and long-term potentiation
    • Lledo, P. M., Zhang, X., Sudhof, T. C., Malenka, R. C. & Nicoll, R. A. Postsynaptic membrane fusion and long-term potentiation. Science 279, 399-403 (1998).
    • (1998) Science , vol.279 , pp. 399-403
    • Lledo, P.M.1    Zhang, X.2    Sudhof, T.C.3    Malenka, R.C.4    Nicoll, R.A.5
  • 27
    • 0033153222 scopus 로고    scopus 로고
    • Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism
    • Noel, J. et al. Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism. Neuron 23, 365-376 (1999).
    • (1999) Neuron , vol.23 , pp. 365-376
    • Noel, J.1
  • 28
    • 1542310123 scopus 로고    scopus 로고
    • Role of AMPA receptor cycling in synaptic transmission and plasticity
    • Luscher, C. et al. Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron 24, 649-658 (1999). This paper provides evidence for a crucial role of dynamin-dependent endocytosis of postsynaptic AMPARs in the expression of LTD in hippocampal CA1.
    • (1999) Neuron , vol.24 , pp. 649-658
    • Luscher, C.1
  • 29
    • 0035875691 scopus 로고    scopus 로고
    • A labile component of AMPA receptor-mediated synaptic transmission is dependent on microtubule motors, actin, and N-ethylmaleimide-sensitive factor. J
    • Kim, C. H. & Lisman, J. E. A labile component of AMPA receptor-mediated synaptic transmission is dependent on microtubule motors, actin, and N-ethylmaleimide-sensitive factor. J. Neurosci. 21, 4188-4194 (2001).
    • (2001) Neurosci. , vol.21 , pp. 4188-4194
    • Kim, C.H.1    Lisman, J.E.2
  • 30
    • 0035970107 scopus 로고    scopus 로고
    • Contribution of cytoskeleton to the internalization of AMPA receptors
    • Zhou, Q., Xiao, M. & Nicoll, R. A. Contribution of cytoskeleton to the internalization of AMPA receptors. Proc. Natl Acad. Sci. USA 98, 1261-1266 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1261-1266
    • Zhou, Q.1    Xiao, M.2    Nicoll, R.A.3
  • 31
    • 0034332508 scopus 로고    scopus 로고
    • Regulation of AMPA receptor GluR1 subunit surface expression by a 4.1N-linked actin cytoskeletal association
    • Shen, L., Liang, F., Walensky, L. D. & Huganir, R. L. Regulation of AMPA receptor GluR1 subunit surface expression by a 4.1N-linked actin cytoskeletal association. J. Neurosci. 20, 7932-7940 (2000).
    • (2000) J. Neurosci. , vol.20 , pp. 7932-7940
    • Shen, L.1    Liang, F.2    Walensky, L.D.3    Huganir, R.L.4
  • 32
    • 0033681557 scopus 로고    scopus 로고
    • Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization
    • Man, H. Y. et al. Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization. Neuron 25, 649-662 (2000). Direct evidence that clathrin-dependent internalization of AMPARs is involved in LTD at hippocampal CA1 synapses.
    • (2000) Neuron , vol.25 , pp. 649-662
    • Man, H.Y.1
  • 33
    • 0037079062 scopus 로고    scopus 로고
    • Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play distinct roles in AMPA receptor trafficking and hippocampal LTD
    • Lee, S. H., Liu, L., Wang, Y. T. & Sheng, M. Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play distinct roles in AMPA receptor trafficking and hippocampal LTD. Neuron 38, 661-674 (2002). Research showing that NSF and AP2 bind on overlapping regions of GluR2 and that the GluR2-NSF and GluR2-AP2 interactions are involved in maintaining basal synaptic transmission and regulated internalization, respectively.
    • (2002) Neuron , vol.38 , pp. 661-674
    • Lee, S.H.1    Liu, L.2    Wang, Y.T.3    Sheng, M.4
  • 34
    • 0033713293 scopus 로고    scopus 로고
    • Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis
    • Wang, Y. T. & Linden, D. J. Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis. Neuron 25, 635-647 (2000).
    • (2000) Neuron , vol.25 , pp. 635-647
    • Wang, Y.T.1    Linden, D.J.2
  • 35
    • 3242656596 scopus 로고    scopus 로고
    • Subunit rules governing the sorting of internalized AMPA receptors in hippocampal neurons
    • Lee, S. H., Simonetta, A. & Sheng, M. Subunit rules governing the sorting of internalized AMPA receptors in hippocampal neurons. Neuron 43, 221-236 (2004).
    • (2004) Neuron , vol.43 , pp. 221-236
    • Lee, S.H.1    Simonetta, A.2    Sheng, M.3
  • 36
    • 0030900558 scopus 로고    scopus 로고
    • GRIP: A synaptic PDZ domain-containing protein that interacts with AMPA receptors
    • Dong, H. et al. GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors. Nature 386, 279-284 (1997).
    • (1997) Nature , vol.386 , pp. 279-284
    • Dong, H.1
  • 37
    • 0033724730 scopus 로고    scopus 로고
    • Mutagenesis reveals a role for ABP/GRIP binding to GluR2 in synaptic surface accumulation of the AMPA receptor
    • Osten, P. et al. Mutagenesis reveals a role for ABP/GRIP binding to GluR2 in synaptic surface accumulation of the AMPA receptor. Neuron 27, 313-325 (2000).
    • (2000) Neuron , vol.27 , pp. 313-325
    • Osten, P.1
  • 38
    • 0034523581 scopus 로고    scopus 로고
    • PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses
    • Daw, M. I. et al. PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses. Neuron 28, 873-886 (2000). The first electrophysiological evidence that PICK1 and GRIP/ABP interactions with synaptic AMPARs are involved in acute regulation of hippocampal synaptic function and LTD.
    • (2000) Neuron , vol.28 , pp. 873-886
    • Daw, M.I.1
  • 39
    • 0036584774 scopus 로고    scopus 로고
    • Differential palmitoylation directs the AMPA receptor-binding protein ABP to spines or to intracellular clusters
    • DeSouza, S., Fu, J., States, B. A. & Ziff, E. B. Differential palmitoylation directs the AMPA receptor-binding protein ABP to spines or to intracellular clusters. J. Neurosci. 22, 3493-3503 (2002).
    • (2002) J. Neurosci. , vol.22 , pp. 3493-3503
    • DeSouza, S.1    Fu, J.2    States, B.A.3    Ziff, E.B.4
  • 40
    • 0037007668 scopus 로고    scopus 로고
    • Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites
    • Setou, M. et al. Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites. Nature 417, 83-87 (2002).
    • (2002) Nature , vol.417 , pp. 83-87
    • Setou, M.1
  • 41
    • 0037187640 scopus 로고    scopus 로고
    • Interaction between GRIP and liprin-α/SYD2 is required for AMPA receptor targeting
    • Wyszynski, M. et al. Interaction between GRIP and liprin-α/SYD2 is required for AMPA receptor targeting. Neuron 34, 39-52 (2002).
    • (2002) Neuron , vol.34 , pp. 39-52
    • Wyszynski, M.1
  • 42
    • 0037336858 scopus 로고    scopus 로고
    • Interaction between liprin-α and GIT1 is required for AMPA receptor targeting
    • Ko, J. et al. Interaction between liprin-α and GIT1 is required for AMPA receptor targeting. J. Neurosci. 23, 1667-1677 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 1667-1677
    • Ko, J.1
  • 43
    • 0033679909 scopus 로고    scopus 로고
    • GRASP-1: Aneuronal RasGEF associated with the AMPA receptor/GRIP complex
    • Ye, B. et al. GRASP-1: aneuronal RasGEF associated with the AMPA receptor/GRIP complex. Neuron 26, 603-617 (2000).
    • (2000) Neuron , vol.26 , pp. 603-617
    • Ye, B.1
  • 44
    • 0037162696 scopus 로고    scopus 로고
    • Ras and Rap control AMPA receptor trafficking during synaptic plasticity
    • Zhu, J. J., Qin, Y., Zhao, M., Van Aelst, L. & Malinow, R. Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell 110, 443-455 (2002).
    • (2002) Cell , vol.110 , pp. 443-455
    • Zhu, J.J.1    Qin, Y.2    Zhao, M.3    Van Aelst, L.4    Malinow, R.5
  • 45
    • 0034307444 scopus 로고    scopus 로고
    • Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins
    • Chung, H. J., Xia, J., Scannevin, R. H., Zhang, X. & Huganir, R. L. Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins. J. Neurosci. 20, 7258-7267 (2000).
    • (2000) J. Neurosci. , vol.20 , pp. 7258-7267
    • Chung, H.J.1    Xia, J.2    Scannevin, R.H.3    Zhang, X.4    Huganir, R.L.5
  • 46
    • 0035425710 scopus 로고    scopus 로고
    • PICK1 targets activated protein kinase Cα to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2
    • Perez, J. L. et al. PICK1 targets activated protein kinase Cα to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2. J. Neurosci. 21, 5417-5428 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 5417-5428
    • Perez, J.L.1
  • 47
    • 0037187768 scopus 로고    scopus 로고
    • NSF ATPase and α-/β-SNAPs disassemble the AMPA receptor-PICK1 complex
    • Hanley, J. G., Khatri, L., Hanson, P. I. & Ziff, E. B. NSF ATPase and α-/β-SNAPs disassemble the AMPA receptor-PICK1 complex. Neuron 34, 53-67 (2002).
    • (2002) Neuron , vol.34 , pp. 53-67
    • Hanley, J.G.1    Khatri, L.2    Hanson, P.I.3    Ziff, E.B.4
  • 48
    • 0035949629 scopus 로고    scopus 로고
    • Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression
    • Kim, C. H., Chung, H. J., Lee, H. K. & Huganir, R. L. Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression. Proc. Natl Acad Sci. USA 98, 11725-11730 (2001).
    • (2001) Proc. Natl. Acad Sci. USA , vol.98 , pp. 11725-11730
    • Kim, C.H.1    Chung, H.J.2    Lee, H.K.3    Huganir, R.L.4
  • 49
    • 0032823580 scopus 로고    scopus 로고
    • Phosphorylation of serine-880 in GluR2 by protein kinase C prevents its C terminus from binding with glutamate receptor-interacting protein
    • Matsuda, S., Mikawa, S. & Hirai, H. Phosphorylation of serine-880 in GluR2 by protein kinase C prevents its C terminus from binding with glutamate receptor-interacting protein. J. Neurochem. 73, 1765-1768 (1999).
    • (1999) J. Neurochem. , vol.73 , pp. 1765-1768
    • Matsuda, S.1    Mikawa, S.2    Hirai, H.3
  • 50
    • 0033635165 scopus 로고    scopus 로고
    • Cerebellar long-term depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins
    • Xia, J., Chung, H. J., Wihler, C., Huganir, R. L. & Linden, D. J. Cerebellar long-term depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins. Neuron 28, 499-510 (2000). The first evidence for the molecular mechanism of LTD involving PKC, and the interaction between PICK1 and GluR2/3 AMPAR subunits.
    • (2000) Neuron , vol.28 , pp. 499-510
    • Xia, J.1    Chung, H.J.2    Wihler, C.3    Huganir, R.L.4    Linden, D.J.5
  • 51
    • 2942625634 scopus 로고    scopus 로고
    • Regulation of synaptic strength and AMPA receptor subunit composition by PICK1
    • Terashima, A. et al. Regulation of synaptic strength and AMPA receptor subunit composition by PICK1. J. Neurosci. 24, 5381-5390 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 5381-5390
    • Terashima, A.1
  • 52
    • 12144288368 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD
    • Ahmadian, G. et al. Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD. EMBO J. 23, 1040-1050 (2004).
    • (2004) EMBO J. , vol.23 , pp. 1040-1050
    • Ahmadian, G.1
  • 53
    • 3042794099 scopus 로고    scopus 로고
    • Tyrosine phosphorylation and regulation of the AMPA receptor by SRC family tyrosine kinases
    • Hayashi, T. & Huganir, R. L. Tyrosine phosphorylation and regulation of the AMPA receptor by SRC family tyrosine kinases. J. Neurosci. 24, 6152-6160 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 6152-6160
    • Hayashi, T.1    Huganir, R.L.2
  • 54
    • 0035805143 scopus 로고    scopus 로고
    • Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons
    • Shi, S., Hayashi, Y., Esteban, J. A. & Malinow, R. Subunit-specific rules governing AMPA receptor trafficking to synapses in hippocampal pyramidal neurons. Cell 105, 331-343 (2001).
    • (2001) Cell , vol.105 , pp. 331-343
    • Shi, S.1    Hayashi, Y.2    Esteban, J.A.3    Malinow, R.4
  • 55
    • 3242672694 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase II phosphorylation drives synapse-associated protein 97 into spines
    • Mauceri, D., Cattabeni, F, Di Luca, M. & Gardoni, F. Calcium/calmodulin-dependent protein kinase II phosphorylation drives synapse-associated protein 97 into spines. J. Biol. Chem. 279, 23813-23821 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 23813-23821
    • Mauceri, D.1    Cattabeni, F.2    Di Luca, M.3    Gardoni, F.4
  • 56
    • 0037163078 scopus 로고    scopus 로고
    • Interaction of SAP97 with minus-end-directed actin motor myosin VI. Implications for AMPA receptor trafficking
    • Wu, H., Nash, J. E., Zamorano, P. & Garner, C. C. Interaction of SAP97 with minus-end-directed actin motor myosin VI. Implications for AMPA receptor trafficking. J. Biol. Chem. 277, 30928-30934 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 30928-30934
    • Wu, H.1    Nash, J.E.2    Zamorano, P.3    Garner, C.C.4
  • 57
    • 0034700490 scopus 로고    scopus 로고
    • Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms
    • Chen, L. et al. Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. Nature 408, 936-943 (2000). The first description of the function of stargazin, a protein that was genetically identified as important for motor coordination, showing that stargazin interacts with PSD-95 and is required for the surface expression of AMPARs.
    • (2000) Nature , vol.408 , pp. 936-943
    • Chen, L.1
  • 58
    • 0038045645 scopus 로고    scopus 로고
    • Postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression
    • Stein, V., House, D. R., Bredt, D. S. & Nicoll, R. A. Postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression. J. Neurosci. 23, 5503-5506 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 5503-5506
    • Stein, V.1    House, D.R.2    Bredt, D.S.3    Nicoll, R.A.4
  • 59
    • 0742322856 scopus 로고    scopus 로고
    • Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity
    • Ehrlich, I. & Malinow, R. Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity. J. Neurosci. 24, 916-927 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 916-927
    • Ehrlich, I.1    Malinow, R.2
  • 60
    • 0345119031 scopus 로고    scopus 로고
    • Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression
    • Colledge, M. et al. Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron 40, 595-607 (2003).
    • (2003) Neuron , vol.40 , pp. 595-607
    • Colledge, M.1
  • 61
    • 18344396972 scopus 로고    scopus 로고
    • Synaptic strength regulated by palmitate cycling on PSD-95
    • El-Husseini Ael, D. et al. Synaptic strength regulated by palmitate cycling on PSD-95. Cell 108, 849-863 (2002).
    • (2002) Cell , vol.108 , pp. 849-863
    • El-Husseini Ael, D.1
  • 62
    • 1542317582 scopus 로고    scopus 로고
    • Dynamic interaction of stargazin-like TARPs with cycling AMPA receptors at synapses
    • Tomita, S., Fukata, M., Nicoll, R. A. & Bredt, D. S. Dynamic interaction of stargazin-like TARPs with cycling AMPA receptors at synapses. Science 303, 1508-1511 (2004).
    • (2004) Science , vol.303 , pp. 1508-1511
    • Tomita, S.1    Fukata, M.2    Nicoll, R.A.3    Bredt, D.S.4
  • 63
    • 0027166069 scopus 로고
    • N-Methyl-D-aspartate receptors are clustered and immobilized on dendrites of living cortical neurons
    • Benke, T. A., Jones, O. T., Collingridge, G. L. & Angelides, K. J. N-Methyl-D-aspartate receptors are clustered and immobilized on dendrites of living cortical neurons. Proc. Natl Acad. Sci. USA 90, 7819-7823 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7819-7823
    • Benke, T.A.1    Jones, O.T.2    Collingridge, G.L.3    Angelides, K.J.4
  • 64
    • 3042823541 scopus 로고    scopus 로고
    • Differential activity-dependent regulation of the lateral mobilities of AMPA and NMDA receptors
    • Groc, L et al. Differential activity-dependent regulation of the lateral mobilities of AMPA and NMDA receptors. Nature Neurosci. 7, 695-696 (2004).
    • (2004) Nature Neurosci. , vol.7 , pp. 695-696
    • Groc, L.1
  • 65
    • 0037061686 scopus 로고    scopus 로고
    • Mobile NMDA receptors at hippocampal synapses
    • Tovar, K. R. & Westbrook, G. L. Mobile NMDA receptors at hippocampal synapses. Neuron 34, 255-264 (2002).
    • (2002) Neuron , vol.34 , pp. 255-264
    • Tovar, K.R.1    Westbrook, G.L.2
  • 66
    • 0037223301 scopus 로고    scopus 로고
    • KIF17 dynamics and regulation of NR2B trafficking in hippocampal neurons
    • Guillaud, L., Setou, M. & Hirokawa, N. KIF17 dynamics and regulation of NR2B trafficking in hippocampal neurons. J. Neurosci. 23, 131-140 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 131-140
    • Guillaud, L.1    Setou, M.2    Hirokawa, N.3
  • 67
    • 0036323370 scopus 로고    scopus 로고
    • Rapid recruitment of NMDA receptor transport packets to nascent synapses
    • Washbourne, P., Bennett, J. E. & McAllister, A. K. Rapid recruitment of NMDA receptor transport packets to nascent synapses. Nature Neurosci. 5, 751-759 (2002).
    • (2002) Nature Neurosci. , vol.5 , pp. 751-759
    • Washbourne, P.1    Bennett, J.E.2    McAllister, A.K.3
  • 68
    • 0035503064 scopus 로고    scopus 로고
    • Regulation of NMDA receptor activity by F-actin and myosin light chain kinase
    • Lei, S., Czerwinska, E., Czerwinski, W., Walsh, M. P. & MacDonald, J. F. Regulation of NMDA receptor activity by F-actin and myosin light chain kinase. J. Neurosci. 21, 8464-8472 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 8464-8472
    • Lei, S.1    Czerwinska, E.2    Czerwinski, W.3    Walsh, M.P.4    MacDonald, J.F.5
  • 69
    • 0034520590 scopus 로고    scopus 로고
    • PDZ domain suppression of an ER retention signal in NMDA receptor NR1 splice variants
    • Standley, S., Roche, K. W., McCallum, J., Sans, N. & Wenthold, R. J. PDZ domain suppression of an ER retention signal in NMDA receptor NR1 splice variants. Neuron 28, 887-898 (2000).
    • (2000) Neuron , vol.28 , pp. 887-898
    • Standley, S.1    Roche, K.W.2    McCallum, J.3    Sans, N.4    Wenthold, R.J.5
  • 70
    • 0034941552 scopus 로고    scopus 로고
    • Molecular determinants of NMDA receptor internalization
    • Roche, K. W. et al. Molecular determinants of NMDA receptor internalization. Nature Neurosci. 4, 794-802 (2001).
    • (2001) Nature Neurosci. , vol.4 , pp. 794-802
    • Roche, K.W.1
  • 71
    • 0348010293 scopus 로고    scopus 로고
    • Developmental decrease in NMDA receptor desensitization associated with shift to synapse and interaction with postsynaptic density-95
    • Li, B., Otsu, Y., Murphy, T. H. & Raymond, L. A. Developmental decrease in NMDA receptor desensitization associated with shift to synapse and interaction with postsynaptic density-95. J. Neurosci. 23, 11244-11254 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 11244-11254
    • Li, B.1    Otsu, Y.2    Murphy, T.H.3    Raymond, L.A.4
  • 72
    • 0037456846 scopus 로고    scopus 로고
    • Glycine binding primes NMDA receptor internalization
    • Nong, Y. et al. Glycine binding primes NMDA receptor internalization. Nature 422, 302-307 (2003).
    • (2003) Nature , vol.422 , pp. 302-307
    • Nong, Y.1
  • 73
    • 0037130451 scopus 로고    scopus 로고
    • Subunit-specifc NMDA receptor trafficking to synapses
    • Barria, A. & Malinow, R. Subunit-specifc NMDA receptor trafficking to synapses. Neuron 35, 345-353 (2002).
    • (2002) Neuron , vol.35 , pp. 345-353
    • Barria, A.1    Malinow, R.2
  • 74
    • 0034986665 scopus 로고    scopus 로고
    • A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux
    • Vissel, B., Krupp, J. J., Heinemann, S. F. & Westbrook, G. L. A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux. Nature Neurosci. 4, 587-596 (2001).
    • (2001) Nature Neurosci. , vol.4 , pp. 587-596
    • Vissel, B.1    Krupp, J.J.2    Heinemann, S.F.3    Westbrook, G.L.4
  • 75
    • 0036728049 scopus 로고    scopus 로고
    • Differential regulation of synaptic and extrasynaptic NMDA receptors
    • Li, B. et al. Differential regulation of synaptic and extrasynaptic NMDA receptors. Nature Neurosci. 5, 833-834 (2002).
    • (2002) Nature Neurosci. , vol.5 , pp. 833-834
    • Li, B.1
  • 76
    • 0035853124 scopus 로고    scopus 로고
    • Insulin promotes rapid delivery of N-methyl-D-aspartate receptors to the cell surface by exocytosis
    • Skeberdis, V. A., Lan, J., Zheng, X., Zukin, R. S. & Bennett, M. V. Insulin promotes rapid delivery of N-methyl-D-aspartate receptors to the cell surface by exocytosis. Proc. Natl Acad. Sci. USA 98, 3561-3566 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 3561-3566
    • Skeberdis, V.A.1    Lan, J.2    Zheng, X.3    Zukin, R.S.4    Bennett, M.V.5
  • 77
    • 0035094057 scopus 로고    scopus 로고
    • Protein kinase C modulates NMDA receptor trafficking and gating
    • Lan, J. Y. et al. Protein kinase C modulates NMDA receptor trafficking and gating. Nature Neurosci. 4, 382-390 (2001).
    • (2001) Nature Neurosci. , vol.4 , pp. 382-390
    • Lan, J.Y.1
  • 78
    • 0035882456 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor 1 accelerates NMDA receptor trafficking
    • Lan, J. Y. et al. Activation of metabotropic glutamate receptor 1 accelerates NMDA receptor trafficking. J. Neurosci. 21, 6058-6068 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 6058-6068
    • Lan, J.Y.1
  • 79
    • 0036139881 scopus 로고    scopus 로고
    • LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1
    • Grosshans, D. R., Clayton, D. A., Coultrap, S. J. & Browning, M. D. LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nature Neurosci. 5, 27-33 (2002).
    • (2002) Nature Neurosci. , vol.5 , pp. 27-33
    • Grosshans, D.R.1    Clayton, D.A.2    Coultrap, S.J.3    Browning, M.D.4
  • 80
    • 0038380386 scopus 로고    scopus 로고
    • Roles and rules of kainate receptors in synaptic transmission
    • Lerma, J. Roles and rules of kainate receptors in synaptic transmission. Nature Rev. Neurosci. 4, 481-495 (2003).
    • (2003) Nature Rev. Neurosci. , vol.4 , pp. 481-495
    • Lerma, J.1
  • 81
    • 0033581849 scopus 로고    scopus 로고
    • Kainate receptors are involved in synaptic plasticity
    • Bortolotto, Z. A. et al. Kainate receptors are involved in synaptic plasticity. Nature 402, 297-301 (1999).
    • (1999) Nature , vol.402 , pp. 297-301
    • Bortolotto, Z.A.1
  • 82
    • 0033526998 scopus 로고    scopus 로고
    • Developmental and activity-dependent regulation of kainate receptors at thalamocortical synapses
    • Kidd, F. L. & Isaac, J. T. Developmental and activity-dependent regulation of kainate receptors at thalamocortical synapses. Nature 400, 569-573 (1999).
    • (1999) Nature , vol.400 , pp. 569-573
    • Kidd, F.L.1    Isaac, J.T.2
  • 83
    • 0032191152 scopus 로고    scopus 로고
    • SAP90 binds and clusters kainate receptors causing incomplete desensitization
    • Garcia, E. P. et al. SAP90 binds and clusters kainate receptors causing incomplete desensitization. Neuron 21, 727-739 (1998).
    • (1998) Neuron , vol.21 , pp. 727-739
    • Garcia, E.P.1
  • 84
    • 0346101760 scopus 로고    scopus 로고
    • Cell surface expression of GluR5 kainate receptors is regulated by an endoplasmic reticulum retention signal
    • Ren, Z. et al. Cell surface expression of GluR5 kainate receptors is regulated by an endoplasmic reticulum retention signal. J. Biol. Chem. 278, 52700-52709 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 52700-52709
    • Ren, Z.1
  • 85
    • 1542327616 scopus 로고    scopus 로고
    • Subunit composition and alternative splicing regulate membrane delivery of kainate receptors
    • Jaskolski, F. et al. Subunit composition and alternative splicing regulate membrane delivery of kainate receptors. J. Neurosci. 24, 2506-2515 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 2506-2515
    • Jaskolski, F.1
  • 86
    • 0141767089 scopus 로고    scopus 로고
    • Assembly and cell surface expression of KA-2 subunit-containing kainate receptors
    • Gallyas, F., Jr, Ball, S. M. & Molnar, E. Assembly and cell surface expression of KA-2 subunit-containing kainate receptors. J. Neurochem. 86, 1414-1427 (2003).
    • (2003) J. Neurochem. , vol.86 , pp. 1414-1427
    • Gallyas Jr., F.1    Ball, S.M.2    Molnar, E.3
  • 87
    • 0037456522 scopus 로고    scopus 로고
    • Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP
    • Hirbec, H. et al. Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP. Neuron 37, 625-638 (2003).
    • (2003) Neuron , vol.37 , pp. 625-638
    • Hirbec, H.1
  • 88
    • 0842284000 scopus 로고    scopus 로고
    • A C-terminal determinant of GluR6 kainate receptor trafficking
    • Yan, S. et al. A C-terminal determinant of GluR6 kainate receptor trafficking. J. Neurosci. 24, 679-691 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 679-691
    • Yan, S.1
  • 89
    • 0032907608 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: Electrophysiological properties and role in plasticity
    • Anwyl, R. Metabotropic glutamate receptors: electrophysiological properties and role in plasticity. Brain Res. Brain Res. Rev. 29, 83-120 (1999).
    • (1999) Brain Res. Brain Res. Rev. , vol.29 , pp. 83-120
    • Anwyl, R.1
  • 90
    • 0028287907 scopus 로고
    • A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation
    • Bortolotto, Z. A., Bashir, Z. I., Davies, C. H. & Collingridge, G. L. A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation. Nature 368, 740-743 (1994).
    • (1994) Nature , vol.368 , pp. 740-743
    • Bortolotto, Z.A.1    Bashir, Z.I.2    Davies, C.H.3    Collingridge, G.L.4
  • 91
    • 0028244082 scopus 로고
    • Postsynaptic induction and presynaptic expression of hippocampal long-term depression
    • Bolshakov, V. Y. & Siegelbaum, S. A. Postsynaptic induction and presynaptic expression of hippocampal long-term depression. Science 264, 1148-1152 (1994).
    • (1994) Science , vol.264 , pp. 1148-1152
    • Bolshakov, V.Y.1    Siegelbaum, S.A.2
  • 92
    • 2342470026 scopus 로고    scopus 로고
    • Identification and functional roles of metabotropic glutamate receptor-interacting proteins
    • Fagni, L., Ango, F., Perroy, J. & Bockaert, J. Identification and functional roles of metabotropic glutamate receptor-interacting proteins. Semin. Cell Dev. Biol. 15, 289-298 (2004).
    • (2004) Semin. Cell Dev. Biol. , vol.15 , pp. 289-298
    • Fagni, L.1    Ango, F.2    Perroy, J.3    Bockaert, J.4
  • 93
    • 0034548876 scopus 로고    scopus 로고
    • Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by homer1 proteins and neuronal excitation
    • Ango, F. et al. Dendritic and axonal targeting of type 5 metabotropic glutamate receptor is regulated by homer1 proteins and neuronal excitation. J. Neurosci. 20, 8710-8716 (2000).
    • (2000) J. Neurosci. , vol.20 , pp. 8710-8716
    • Ango, F.1
  • 94
    • 0039107899 scopus 로고    scopus 로고
    • Homer 1b regulates the trafficking of group I metabotropic glutamate receptors
    • Roche, K. W. et al. Homer 1b regulates the trafficking of group I metabotropic glutamate receptors. J. Biol. Chem. 274, 25953-25957 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 25953-25957
    • Roche, K.W.1
  • 95
    • 0033565534 scopus 로고    scopus 로고
    • Rapid internalization and surface expression of a functional, fluorescently tagged G-protein-coupled glutamate receptor
    • Doherty, A. J., Coutinho, V., Collingridge, G. L. & Henley, J. M. Rapid internalization and surface expression of a functional, fluorescently tagged G-protein-coupled glutamate receptor. Biochem. J. 341, 415-422 (1999).
    • (1999) Biochem. J. , vol.341 , pp. 415-422
    • Doherty, A.J.1    Coutinho, V.2    Collingridge, G.L.3    Henley, J.M.4
  • 96
    • 0034911135 scopus 로고    scopus 로고
    • Agonist-induced internalization of the metabotropic glutamate receptor 1a is arrestin- and dynamin-dependent
    • Mundell, S. J., Matharu, A. L., Pula, G., Roberts, P. J. & Kelly, E. Agonist-induced internalization of the metabotropic glutamate receptor 1a is arrestin- and dynamin-dependent J. Neurochem. 78, 546-551 (2001).
    • (2001) J. Neurochem. , vol.78 , pp. 546-551
    • Mundell, S.J.1    Matharu, A.L.2    Pula, G.3    Roberts, P.J.4    Kelly, E.5
  • 97
    • 0037095771 scopus 로고    scopus 로고
    • Receptor actuation and homer differentially control the lateral mobility of metabotropic glutamate receptor 5 in the neuronal membrane
    • Serge, A., Fourgeaud, L., Hemar, A. & Choquet, D. Receptor actuation and homer differentially control the lateral mobility of metabotropic glutamate receptor 5 in the neuronal membrane. J. Neurosci. 22, 3910-3920 (2002).
    • (2002) J. Neurosci. , vol.22 , pp. 3910-3920
    • Serge, A.1    Fourgeaud, L.2    Hemar, A.3    Choquet, D.4
  • 98
    • 0036828550 scopus 로고    scopus 로고
    • Long-term plasticity at GABAergic and glycinergic synapses: Mechanisms and functional significance
    • Gaiarsa, J. L., Caillard, O. & Ben-Ari, Y. Long-term plasticity at GABAergic and glycinergic synapses: mechanisms and functional significance. Trends Neurosci. 25, 564-570 (2002).
    • (2002) Trends Neurosci. , vol.25 , pp. 564-570
    • Gaiarsa, J.L.1    Caillard, O.2    Ben-Ari, Y.3
  • 99
    • 0032505048 scopus 로고    scopus 로고
    • A receptors underlies potentiation at hippocampal inhibitory synapses
    • A receptors underlies potentiation at hippocampal inhibitory synapses. Nature 395, 172-177 (1998).
    • (1998) Nature , vol.395 , pp. 172-177
    • Nusser, Z.1    Hajos, N.2    Somogyi, P.3    Mody, I.4
  • 100
    • 0038383457 scopus 로고    scopus 로고
    • A receptor activity by phosphorylation and receptor trafficking: Implications for the efficacy of synaptic inhibition
    • A receptor activity by phosphorylation and receptor trafficking: implications for the efficacy of synaptic inhibition. Curr. Opin. Neurobiol. 13, 341-347 (2003).
    • (2003) Curr. Opin. Neurobiol. , vol.13 , pp. 341-347
    • Kittler, J.T.1    Moss, S.J.2
  • 101
    • 0030800192 scopus 로고    scopus 로고
    • A receptors to postsynaptic domains by insulin
    • ARs can be rapidly increased by translocation from an intracellular compartment to postsynaptic membranes, and that this is a powerful means of strengthening synaptic efficacy.
    • (1997) Nature , vol.388 , pp. 686-690
    • Wan, Q.1
  • 102
    • 0037523369 scopus 로고    scopus 로고
    • Control of synaptic strength, a novel function of Akt
    • Wang, Q. et al. Control of synaptic strength, a novel function of Akt. Neuron 38, 915-928 (2003).
    • (2003) Neuron , vol.38 , pp. 915-928
    • Wang, Q.1
  • 104
    • 0034310719 scopus 로고    scopus 로고
    • A receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons
    • AR endocytosis regulates synaptic transmission in cultured hippocampal neurons.
    • (2000) J. Neurosci. , vol.20 , pp. 7972-7977
    • Kittler, J.T.1
  • 105
    • 0024327605 scopus 로고
    • Distribution and lateral mobility of GABA/benzodiazepine receptors on nerve cells
    • Velazquez, J. L., Thompson, C. L., Barnes, E. M., Jr & Angelides, K. J. Distribution and lateral mobility of GABA/benzodiazepine receptors on nerve cells. J. Neurosci. 9, 2163-2169 (1989).
    • (1989) J. Neurosci. , vol.9 , pp. 2163-2169
    • Velazquez, J.L.1    Thompson, C.L.2    Barnes Jr., E.M.3    Angelides, K.J.4
  • 107
    • 0037119360 scopus 로고    scopus 로고
    • A receptor-associated protein, GRIF-1
    • A receptor-associated protein, GRIF-1. J. Biol. Chem. 277, 30079-30090 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 30079-30090
    • Beck, M.1
  • 109
    • 17944363387 scopus 로고    scopus 로고
    • A receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1
    • A receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1. Nature Neurosci. 4, 908-916 (2001).
    • (2001) Nature Neurosci. , vol.4 , pp. 908-916
    • Bedford, F.K.1
  • 113
    • 0035002957 scopus 로고    scopus 로고
    • B receptors couple directly to the transcription factor ATF4
    • B receptors couple directly to the transcription factor ATF4. Mol. Cell. Neurosci. 17, 637-645 (2001).
    • (2001) Mol. Cell. Neurosci. , vol.17 , pp. 637-645
    • Vemon, E.1
  • 114
    • 0034634083 scopus 로고    scopus 로고
    • B receptor directly interacts with the activating transcription factor 4
    • B receptor directly interacts with the activating transcription factor 4. J. Biol. Chem. 275, 35185-35191 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 35185-35191
    • Nehring, R.B.1
  • 115
    • 0034610183 scopus 로고    scopus 로고
    • B receptor interacts directly with the related transcription factors CREB2 and ATFx
    • B receptor interacts directly with the related transcription factors CREB2 and ATFx. Proc. Natl Acad. Sci. USA 97, 13967-13972 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13967-13972
    • White, J.H.1
  • 116
    • 9944255035 scopus 로고    scopus 로고
    • B receptors
    • B receptors. J. Biol. Chem. 278, 3934-3943 (2004).
    • (2004) J. Biol. Chem. , vol.278 , pp. 3934-3943
    • Couve, A.1
  • 117
    • 0036237975 scopus 로고    scopus 로고
    • B receptor-effector coupling
    • B receptor-effector coupling. Nature Neurosci. 5, 415-424 (2002).
    • (2002) Nature Neurosci. , vol.5 , pp. 415-424
    • Couve, A.1
  • 118
    • 0024341227 scopus 로고
    • Mechanism for the Hebb and the anti-Hebb processes underlying learning and memory
    • Lisman, J. A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory. Proc. Natl Acad. Sci. USA 86, 9574-9578 (1989).
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 9574-9578
    • Lisman, J.A.1
  • 119
    • 0028813106 scopus 로고
    • Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor ε1 subunit
    • Sakimura, K. et al. Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor ε1 subunit. Nature 373, 151-155 (1995).
    • (1995) Nature , vol.373 , pp. 151-155
    • Sakimura, K.1
  • 120
    • 0343376448 scopus 로고    scopus 로고
    • Long-term potentiation and long-term depression are induced through pharmacologically distinct NMDA receptors
    • Hrabetova, S. & Sacktor, T. C. Long-term potentiation and long-term depression are induced through pharmacologically distinct NMDA receptors. Neurosci. Lett. 226, 107-110 (1997).
    • (1997) Neurosci. Lett. , vol.226 , pp. 107-110
    • Hrabetova, S.1    Sacktor, T.C.2
  • 121
    • 0012107261 scopus 로고    scopus 로고
    • Distinct NMDA receptor subpopulations contribute to long-term potentiation and long-term depression induction
    • Hrabetova, S. et al. Distinct NMDA receptor subpopulations contribute to long-term potentiation and long-term depression induction. J. Neurosci. 20, RC81 (2000).
    • (2000) J. Neurosci. , vol.20
    • Hrabetova, S.1
  • 122
    • 0042163180 scopus 로고    scopus 로고
    • Neocortical LTD via coincident activation of presynaptic NMDA and cannabinoid receptors
    • Sjostrom, P. J., Turrigiano, G. G. & Nelson, S. B. Neocortical LTD via coincident activation of presynaptic NMDA and cannabinoid receptors. Neuron 39, 641-654 (2003).
    • (2003) Neuron , vol.39 , pp. 641-654
    • Sjostrom, P.J.1    Turrigiano, G.G.2    Nelson, S.B.3
  • 124
    • 0042343809 scopus 로고    scopus 로고
    • Two forms of synaptic plasticity with distinct dependence on age, experience, and NMDA receptor subtype in rat visual cortex
    • Yoshimura, Y., Ohmura, T. & Komatsu, Y. Two forms of synaptic plasticity with distinct dependence on age, experience, and NMDA receptor subtype in rat visual cortex. J. Neurosci. 23, 6557-6566 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 6557-6566
    • Yoshimura, Y.1    Ohmura, T.2    Komatsu, Y.3
  • 125
    • 13344261412 scopus 로고    scopus 로고
    • Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor ε2 subunit mutant mice
    • Kutsuwada, T. et al. Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor ε2 subunit mutant mice. Neuron 16, 333-344 (1996).
    • (1996) Neuron , vol.16 , pp. 333-344
    • Kutsuwada, T.1
  • 126
    • 0033517366 scopus 로고    scopus 로고
    • Genetic enhancement of learning and memory in mice
    • Tang, Y. P. et al. Genetic enhancement of learning and memory in mice. Nature 401, 63-69 (1999).
    • (1999) Nature , vol.401 , pp. 63-69
    • Tang, Y.P.1
  • 127
    • 0036583275 scopus 로고    scopus 로고
    • A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat
    • Clayton, D. A., Mesches, M. H., Alvarez, E., Bickford, P. C. & Browning, M. D. A hippocampal NR2B deficit can mimic age-related changes in long-term potentiation and spatial learning in the Fischer 344 rat. J. Neurosci. 22, 3628-3637 (2002).
    • (2002) J. Neurosci. , vol.22 , pp. 3628-3637
    • Clayton, D.A.1    Mesches, M.H.2    Alvarez, E.3    Bickford, P.C.4    Browning, M.D.5
  • 128
    • 0032559283 scopus 로고    scopus 로고
    • Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo
    • Sprengel, R. et al. Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell 92, 279-289 (1998).
    • (1998) Cell , vol.92 , pp. 279-289
    • Sprengel, R.1
  • 129
    • 2342637165 scopus 로고    scopus 로고
    • Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity
    • Liu, L. et al. Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science 304, 1021-1024 (2004). This study showed that activation of NR2A- and NR2B-containing NMDAR subpopulations is required for hippocampal homosynaptic LTP and LTD, respectively. Therefore, this paper provides strong evidence that NR2 subunit composition might be a crucial molecular determinant that dictates the polarity of synaptic plasticity.
    • (2004) Science , vol.304 , pp. 1021-1024
    • Liu, L.1
  • 130
    • 4544373236 scopus 로고    scopus 로고
    • Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression
    • Massey, P. V. et al. Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression. J. Neurosci. 24, 7821-7828 (2004). This paper shows that activation of extrasynaptic NR2B-containing NMDARs is both necessary and sufficient for LTD, and that activation of synaptic NR2A-containing NMDARs is required for LTP and its reversal, depotentiation at cortical synapses. This was the first evidence for a crucial role of NMDAR localization in synaptic plasticity and also indicates that distinct mechanisms might underlie depotentiation and de novo LTD.
    • (2004) J. Neurosci. , vol.24 , pp. 7821-7828
    • Massey, P.V.1
  • 131
    • 0032520117 scopus 로고    scopus 로고
    • Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons
    • Stocca, G. & Vicini, S. Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons. J. Physiol. 507, 13-24 (1998).
    • (1998) J. Physiol. , vol.507 , pp. 13-24
    • Stocca, G.1    Vicini, S.2
  • 132
    • 2442711477 scopus 로고    scopus 로고
    • NR2B-containing receptors mediate cross talk among hippocampal synapses
    • Scimemi, A., Fine, A., Kullmann, D. M. & Rusakov, D. A. NR2B-containing receptors mediate cross talk among hippocampal synapses. J. Neurosci. 24, 4767-4777 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 4767-4777
    • Scimemi, A.1    Fine, A.2    Kullmann, D.M.3    Rusakov, D.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.