Synaptic strength regulated by palmitate cycling on PSD-95

Cell

Volumn 108, Issue 6, 2002, Pages 849-863

  El Husseini, Alaa El Din ^a,c   Schnell, Eric ^b   Dakoji, Srikanth ^a   Sweeney, Neal ^a   Zhou, Qiang ^b   Prange, Oliver ^c   Gauthier Campbell, Catherine ^c   Aguilera Moreno, Andrea ^a   Nicoll, Roger A ^a,b   Bredt, David S ^a  

^a Department of Physiology ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; GLUTAMATE RECEPTOR; PALMITIC ACID; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN; PROTEIN STARGAZIN; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; INTERNALIZATION; NERVE CELL PLASTICITY; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN METABOLISM; RAT; REGULATORY MECHANISM;

ANIMALIA;

EID: 18344396972     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)00683-9     Document Type: Article

References (57)

1. The metabotropic glutamate receptor mGluR4, but not mGluR1 alpha, is palmitoylated when expressed in BHK cells
2. Inhibition of the receptor-mediated endocytosis of diferric transferrin is associated with the covalent modification of the transferrin receptor with palmitic acid
3. Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD
4. Synthesis and use of iodo-fatty acid analogs
5. Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and α-1 syntrophin mediated by PDZ motifs
6. Cloning and characterization of postsynaptic density 93 (PSD-93), a nitric oxide synthase interacting protein
7. Optimized survival of hippocampal neurons in 3-27-supplemented neurohasal, a new serum-free medium combination
8. + channels by PSD-95
9. Stargazin mediates synaptic targeting of AMPA receptors by two distinct mechanisms
10. The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein
11. PDZ proteins organize synaptic signaling pathways
12. Synaptic targeting of the postsynaptic density protein PSD-95 mediated by lipid and protein motifs
13. Signalling functions of protein palmitoylation
14. Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting
15. Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering
16. PSD-95 involvement in maturation of excitatory synapses
17. Ion channel clustering by membrane-associated guanylate kinases. Regulation by N-terminal lipid and metal binding motifs
18. PDZ domains in synapse assembly and signalling
19. Driving AMPA receptors into synapses by LTP and CaMKII: Requirement for GluR1 and PDZ domain interaction
20. Binding of neuroligins to PSD-95
21. Internalization of the Kv1.4 potassium channel is suppressed by clustering interactions with PSD-95
22. The postsynaptic density at glutamatergic synapses
23. + channels by direct interaction with the PSD-95/SAP90 family of membrane-associated guanylate kinases
24. Heteromultimerization and NMDA receptor clustering activity of chapsyn-110, a novel member of the PSD-95 family of synaptic proteins
25. GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules
26. SAP90, a rat presynaptic protein related to the product of the Drosophila tumor suppressor gene dlg-A
27. Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation
28. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
29. Interaction of ion channels and receptors with PDZ domains
30. Development of neuron-neuron synapses
31. SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit
32. Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization
33. Role of AMPA receptor cycling in synaptic transmission and plasticity
34. Long-term potentiation - A decade of progress?
35. LTP mechanisms: From silence to four-lane traffic
36. Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization
37. Identification of an intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95
38. Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein
39. The dynamic role of palmitoylation in signal transduction
40. The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2B
41. Reversible palmitoylation of signaling proteins
42. Microtubule binding by CRIPT and its potential role in the synaptic clustering of PSD-95
43. Palmitoylation of the GluR6 kainate receptor
44. Regulation of cellular signalling by fatty acid acylation and prenylation of signal transduction proteins
45. Fatty acylation of proteins: New insights into membrane targeting of myristoylated and palmitoylated proteins
46. Agonist-modulated palmitoylation of endothelial nitric oxide synthase
47. An intramolecular interaction between Src homology 3 domain and guanylate kinase-like domain required for channel clustering by postsynaptic density-95/SAP90
48. + channels in vivo
49. +) channel surface expression and clustering
50. PDZ protein interactions regulating glutamate receptor function and plasticity
51. + channel, Kv1.4
52. Inhibition of brain G(z) GAP and other RGS proteins by palmitoylation of G protein alpha subunits
53. Proteins of the synaptic junction
54. Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids
55. Activation and depalmitoylation of Gs alpha
56. Differential palmitoylation of two mouse glutamate receptor interaction protein isoforms with different N-terminal sequences
57. Contribution of cytoskeleton to the internalization of AMPA receptors