PICK1 targets activated protein kinase Cα to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2

Journal of Neuroscience

Volumn 21, Issue 15, 2001, Pages 5417-5428

  Perez, Jose L ^a,b   Khatri, Latika ^a   Chang, Craig ^a   Srivastava, Sapna ^a,c   Osten, Pavel ^a,d   Ziff, Edward B ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SUGEN INC   (United States)

^c JP Morgan Chase & Co   (United States)

^d MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

Endocytosis; GluR2; PDZ domain; PICK1; PKC ; Spine

Indexed keywords

AMPA RECEPTOR;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; HIPPOCAMPUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; PROTEIN TRANSPORT; RAT; SYNAPTIC TRANSMISSION;

EID: 0035425710     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-15-05417.2001     Document Type: Article

References (47)

1. Presynaptic clustering of mGluR7a requires the PICK1 PDZ domain binding site
2. Differential cellular and subcellular localization of the AMPA receptor-binding protein and glutamate receptor-interacting protein
3. Homology modeling by the ICM method
4. Dynamin-dependent endocytosis of ionotropic glutamate receptors
5. Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex
6. Phosphorylation of the AMPA receptor subunit GluR2 differentially regulates its interaction with PDZ domain-containing proteins
7. The coatomer protein β′-COP, a selective binding protein (RACK) for protein kinase Cε
8. PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses
9. The protein kinase Cα binding protein PICK1 interacts with short but not long form alternative splice variants of AMPA receptor subunits
10. PICK1 interacts with and regulates PKC phosphorylation of mGLUR7
11. GRIP: A synaptic PDZ domain-containing protein that interacts with AMPA receptors
12. Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ
13. Interaction of the C-terminal tail region of the metabotropic glutamate receptor 7 with the protein kinase C substrate PICK1
14. Calcium/calmodulin-dependent protein kinase II is associated with NR2A/B subunits of NMDA receptor in postsynaptic densities
15. Driving AMPA receptors into synapses by LTP and CaMKII: Requirement for GluR1 and PDZ domain interaction
16. Cloned glutamate receptors
17. Phosphorylation of the InaD gene product, a photoreceptor membrane protein required for recovery of visual excitation
18. 2+ channel essential for phosphoinositide-mediated photoreception, forms a signaling complex with NorpA, InaC, and InaD
19. 2+, phospholipid-dependent protein kinase associated with plasma membrane
20. SAP97 is associated with the α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit
21. Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-D-aspartate receptor
22. Synaptic plasticity and dynamic modulation of the postsynaptic membrane
23. LTP mechanisms: From silence to four-lane traffic
24. Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization
25. Phosphorylation of serine-880 in GluR2 by protein kinase C prevents its C terminus from binding with glutamate receptor-interacting protein
26. Disruption of AMPA receptor GluR2 clusters following long-term depression induction in cerebellar Purkinje neurons
27. Regulation of protein kinase C
28. Reversible exposure of the pseudosubstrate domain of protein kinase C by phosphatidylserine and diacylglycerol
29. The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and α- and β-SNAPs
30. Mutagenesis reveals a role for ABP/GRIP binding to GluR2 in synaptic surface accumulation of the AMPA receptor
31. The trends in neuroscience/TiPS lecture. The molecular biology of mammalian glutamate receptor channels
32. Dynamic control of CaMKII translocation and localization in hippocampal neurons by NMDA receptor stimulation
33. Immunocytochemical evidence for phorbol ester-induced protein kinase C translocation in HL60 cells
34. Recognition of unique carboxyl-terminal motifs by distinct PDZ domains
35. Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP
36. PICK1: A perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system
37. Specific interaction of the PDZ domain protein PICK1 with the COOH terminus of protein kinase C-α
38. Autophosphorylation-dependent targeting of calcium/calmodulin-dependent protein kinase II by the NR2B subunit of the N-methyl-D-aspartate receptor
39. Translocation of autophosphorylated calcium/calmodulin-dependent protein kinase II to the postsynaptic density
40. Mechanism and regulation of calcium/calmodulin-dependent protein kinase II targeting to the NR2B subunit of the N-methyl-D-aspartate receptor
41. Interaction of the PDZ domain of human PICK1 with class I ADP-ribosylation factors
42. PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands
43. Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis
44. Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1
45. Cerebellar long-term depression requires PKC-regulated interactions between GIuR2/3 and PDZ domain-containing proteins
46. Glutamate receptor targeting to synaptic populations on Purkinje cells is developmentally regulated
47. Enlightening the postsynaptic density