GABAA receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1

Nature Neuroscience

Volumn 4, Issue 9, 2001, Pages 908-916

  Bedford, Fiona K ^a   Kittler, Josef T ^a   Muller, Emilie ^b   Thomas, Philip ^c   Uren, Julia M ^a   Merlo, Daniela ^d   Wisden, William ^d   Triller, Antoine ^b   Smart, Trevor G ^c   Moss, Stephen J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ECOLE NORMALE SUPÉRIEURE   (France)

^c UNIVERSITY OF LONDON   (United Kingdom)

^d MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; PROTEIN PLIC 1; RECEPTOR SUBUNIT; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL COUNT; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; DENDRITE; NERVE CELL; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; RAT; RECEPTOR INTRINSIC ACTIVITY; SYNAPTIC INHIBITION; SYNAPTIC MEMBRANE;

ANIMALS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CELL MEMBRANE; DRUG STABILITY; PROTEIN ISOFORMS; RATS; RECEPTORS, GABA-A; SUBCELLULAR FRACTIONS; TISSUE DISTRIBUTION; UBIQUITINS;

EID: 17944363387     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn0901-908     Document Type: Article

References (43)

1. A receptor channels
2. A receptor research
3. A receptor subunit
4. Theta, a novel γ-aminobutyric acid type A receptor subunit
5. Neurotransmitter action: Opening of ligand-gated ion channels
6. A receptor subtypes requires the γ2 subunit and gephyrin
7. A receptor clustering in gephyrin-deficient mice
8. Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity
9. A receptors
10. A receptors and the cytoskeleton
11. A receptors to postsynaptic domains by insulin
12. A receptors underlies potentiation at hippocampal inhibitory
13. A receptor number underlie variation in GABA mini amplitude
14. Constructing inhibitory synapses
15. Subcellular localization and endocytosis of homomeric γ2 subunit splice variants of γ-aminobutyric acid type A receptors
16. Cell surface stability of γ-aminobutyric acid type A receptors. Dependence on protein kinase C activity and subunit composition
17. A receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons
18. A receptor assembly in mammalian cell lines and hippocampal neurons using γ2 subunit green fluorescent protein chimeras
19. The structural era of endocytosis
20. Ubiquitin-related proteins regulate interaction of vimentin intermediate filaments with the plasma membrane
21. The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome
22. A novel genetic system to detect protein-protein interactions
23. GRIP: A synaptic PDZ domain-containing protein that interacts with AMPA receptors
24. Identification of XDRP1; a Xenopus protein related to yeast Dsk2p binds to the N-terminus of cyclin A and inhibits its degradation
25. Ubiquitin and its kin: How close are the family ties?
26. The UBA domain: A sequence motif present in multiple enzyme classes of the ubiquitination pathway
27. C receptors to the cytoskeleton at retinal synapses
28. Single step purification of polypeptides expressed in E. Coli as fusions with glutathione S-transferase
29. Distribution, prevalence, and drug binding profile of gamma-aminobutyric acid type A receptor subtypes differing in the beta-subunit variant
30. A receptors
31. A receptors
32. Co-localization of GABA, glycine, and their receptors at synapses in the rat spinal cord
33. Dendritic and postsynaptic protein synthetic machinery
34. Surface expression of AMPA receptors in hippocampal neurons is regulated by a NSF-dependent mechanism
35. Selective inhibition of growth factor-stimulated mitogenesis by a cell-permeable Grb2-binding peptide
36. A receptor β subunits that mediate both homomeric and heteromeric receptor expression
37. A receptor alpha subunits that mediate specific assembly with receptor beta subunits
38. PDZ domains in synapse assembly and signaling
39. Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation
40. A receptors composed of α1 and β2 subunits in both cultured neurones and fibroblasts
41. Localization of components of glycinergic synapses during rat spinal cord development
42. Distribution of glycine receptors at central synapses: An immunoelectron microscopy study