Structural basis and therapeutic implication of the interaction of CCN proteins with glycoconjugates

Current Pharmaceutical Design

Volumn 10, Issue 31, 2004, Pages 3913-3928

  Desnoyers, Luc ^a  

^a GENENTECH INC   (United States)

Author keywords

Cancer; CCN proteins; Glycosaminoglycan; Heparin binding; Proteoglycan; TSR

Indexed keywords

ANTINEOPLASTIC AGENT; AURINTRICARBOXYLIC ACID; CONNECTIVE TISSUE GROWTH FACTOR; CYSTEINE; CYSTEINE RICH PROTEIN 61; GLYCOCONJUGATE; GLYCOSAMINOGLYCAN POLYSULFATE; GROWTH FACTOR; HEMOGLOBIN GAMMA CHAIN; HEPARAN SULFATE; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; MIDKINE; OLIGOSACCHARIDE; POLYSACCHARIDE; PYRAN COPOLYMER; SOMATOMEDIN BINDING PROTEIN; THROMBOSPONDIN; THROMBOSPONDIN 1; THROMBOSPONDIN 2; VON WILLEBRAND FACTOR; WNT1 PROTEIN;

ANGIOGENESIS; ANGIOLIPOMA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; BILE DUCT CARCINOMA; BREAST ADENOCARCINOMA; CANCER INHIBITION; CARBOHYDRATE ANALYSIS; CARCINOGENESIS; CELL ADHESION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CHONDROBLASTOMA; CHONDROSARCOMA; COLON ADENOCARCINOMA; CYTOTOXICITY; DERMATOFIBROMA; DRUG STRUCTURE; DRUG TARGETING; EWING SARCOMA; GENE OVEREXPRESSION; GIANT CELL TUMOR; GLIOBLASTOMA; HEMANGIOENDOTHELIOSARCOMA; HEMANGIOFIBROMA; HUMAN; HYPOTHESIS; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CARCINOMA; MALIGNANT FIBROUS HISTIOCYTOMA; MYOFIBROSIS; NEPHROBLASTOMA; OSTEOSARCOMA; PANCREAS CANCER; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN QUATERNARY STRUCTURE; PROTEIN STRUCTURE; PYOGENIC GRANULOMA; REGULATORY MECHANISM; REVIEW; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; STOMACH ADENOCARCINOMA; TUMOR PROMOTION;

ANIMALS; DRUG DELIVERY SYSTEMS; GLYCOCONJUGATES; GLYCOSAMINOGLYCANS; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR STRUCTURE;

EID: 9944251355     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612043382567     Document Type: Review

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