Neoplastic cells and proliferating endothelial cells express connective tissue growth factor (CTGF) in glioblastoma

Neurological Research

Volumn 24, Issue 7, 2002, Pages 677-683

  Pan, Li Hua ^a   Beppu, Takaaki ^a   Kurose, Akira ^a   Yamauchi, Kohei ^a   Sugawara, Atsushi ^a   Suzuki, Michiyasu ^a   Ogawa, Akira ^a   Sawai, Takashi ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Angiogenesis; Connective tissue growth factor; Endothelial cell; Glioblastoma; Immunohistochemistry; Reverse transcription polymerase chain reaction

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; MESSENGER RNA;

ADOLESCENT; ADULT; AGED; ANGIOGENESIS; ARTICLE; BRAIN TISSUE; CELL PROLIFERATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL; TUMOR GROWTH; VASCULAR TUMOR;

ADOLESCENT; ADULT; AGED; BRAIN NEOPLASMS; CELL DIVISION; CHILD; CHILD, PRESCHOOL; ENDOTHELIUM, VASCULAR; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOBLASTOMA; HUMANS; IMMEDIATE-EARLY PROTEINS; IMMUNOHISTOCHEMISTRY; INFANT; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; RNA, MESSENGER; UP-REGULATION;

EID: 0036787545     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/016164102101200573     Document Type: Article

References (33)

1. Bradham DM, Igarashi A, Potter RI, Grotendorst GR. Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J Cell Biol 1991; 114: 1285-1294
2. Brigstock DR. The connective tissue growth factor/cysteine-rich 61/nephroblast, an overexpressed (CCN) family. Endocrine Rev 1999; 20: 189-206
3. Grotendorst GR. Connective tissue growth factor: A mediator of TGF-Β action on fibroblasts. Cytokine Growth Fact Rev 1997; 8: 171-179
4. Frazier K, Williams S, Kothapalli D, Klapper H, Grotendorst GR. Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor. J Invest Dermatol 1996; 107: 404-411
5. Igarashi A, Nashiro K, Kikuchi K, Sato S, Ihn H, Fujimoto M, Grotendorst GR, Takehara K. Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders. J Invest Dermatol 1996; 106: 729-733
6. Ito Y, Aten J, Bende RJ, Oemar BS, Rabelink TJ, Weening JJ, Goldschmeding R. Expression of connective tissue growth factor in human renal fibrosis. Kidney Int 1998; 53: 853-861
7. Allen JT, Knight RA, Bloor CA, Spiteri MA. Enhanced insulin-like growth factor binding protein-related protein 2 (connective tissue growth factor) expression in patients with idiopathic pulmonary fibrosis and pulmonary sarcoidosis. Am J Resp Cell Mol Biol 1999; 21: 693-700
8. Lasky JA, Ortiz LA, Tonthat B, Hoyle GW, Corti M, Athas G, Lungarella G, Brody A, Friedman M. Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis. Am J Physiol 1998; 275: (Lung Cell Mol Physiol 19): L365-L371
9. Pan L-H, Yamauchi K, Uzuki M, Nakanishi T, Takigawa M, Inoue H, Sawai T. Type II alveolar epithelial cells and interstitial fibroblasts express connective tissue growth factor in idiopathic pulmonary fibrosis. Eur Resp J 2001; 17: 1200-1227
10. Paradis V, Dargere D, Vidaud M, Gouville A-C, Huet S, Martinez V, Gauthier J-M, Ba N, Sobesky R, Ratzui V, Bedossa P. Expression of connective tissue growth factor in experimental rat and human liver fibrosis. Hepatology 1999; 30: 968-976
11. Oemar BS, Werner A, Gamier J-M, Do D, Godoy N, Nauck M, Marz W, Rupp J, Pech M, Luscher TF. Human connective tissue growth factor is expressed in advanced atherosclerotic lesion. Circulation 1997; 95: 831-839
12. Lau LF, Lam SC-T. The CNN family of angiogenic regulator: The integrin connection. Exper Cell Res 1999; 248: 44-57
13. 3, promotes endothelial cell survival, and induces angiogenesis in vivo. Mol Cell Biol 1999; 19: 2958-2966
14. Shimo T, Nakanishi T, Nishida T, Asano M, Kanyama M, Kuboki T, Tamatani T, Tezuka K, Takemura M, Matsumura T, Takigawa M. Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo. J Biochem 1999; 126: 137-145
15. Boehm T, Folkman J, Browder T, O'Reilly MS. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 1997; 390: 404-407
16. Folkman J. Antiangiogenic gene therapy. Proc Natl Acad Sci USA 1998; 95: 9064-9066
17. Folkman J, Shing Y. Angiogenesis. J Biol Chem 1992; 267: 10931-10934
18. Folkman J, Haudenschild C. Angiogenesis in vitro. Nature 1980; 288: 551-556
19. Heldin C-H. Structural and functional studies on platelet-derived growth factor. EMBO J 1992; 11: 4251-4259
20. Sato Y, Tsubori R, Lyons R, Moses H, Rifkin DB. Characterization of the activation of latent TGF-b by co-cultures of endothelial cells and pericytes or smooth muscle cells: A self-regulating system. J Cell Biol 1990; 111: 757-763
21. Schweigerer L, Neufeld G, Friedman J, Abraham JA, Fiddes JC, Gospodarowicz D. Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth. Nature 1987; 325: 257-259
22. Leung DW, Cachianes G, Kuang W-J, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989; 246: 1306-1309
23. Nomura M, Yamagishi S, Harada S, Yamashima T, Yamashita J, Yamamoto H. Placenta growth factor (PIGF) mRNA expression in brain tumors. J Neuro-Oncol 1998; 40: 123-130
24. Holash J, Maisonpierre PC, Compton D, Boland P, Alexander CR, Zagzag D, Yancopoulos GD, Wiegand SJ. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 1999; 284: 1994-1998
25. Burger PC, Scheithauer BW. Atlas of Tumor Pathology: Tumors of the Central Nervous System, Washington, DC: Armed Forces Institute of Pathology, 1994: pp. 49-67
26. Xin LW, Martinerie C, Zumkeller W, Westphal M, Perbal B. Differential expression of novH and CTGF in human glioma cell lines. J Clin Pathol: Mol Pathol 1996; 49: M91-M97
27. Martinerie C, Viegas-Pequignot E, Nguyan VC, Perbal B. Chromosomal mapping and expression of the human cyr61 gene in tumor cells from the nervous system. J Clin Pathol: Med Pathol 1997; 50: 310-316
28. Hertel M, Tretter Y, AIzheimer C, Werner S. Connective tissue growth factor: A novel player in tissue reorganization after brain injury. Eur J Neurosci 2000; 12: 376-380
29. Kondo Y, Nakanishi T, Takigawa M, Ogawa N. Immunohistochemical localization of connective tissue growth factor in the rat central nervous system. Brain Res 1999; 834: 146-151
30. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-159
31. Pan L-H, Yamauchi K, Uzuki M, Nakanishi T, Takigawa M, Inoue H, Sawai T. Type II epithelial cells and interstitial fibroblasts express connective tissue growth factor in IPF. Eur Resp J 2001; 17: 1220-1227
32. Babic AM, Kireeva ML, Kolesnikova TV, Lau LF. CRY61, product of a growth factor-inducible immediate-early gene, promotes angiogenesis and tumor growth. Proc Natl Acad Sci USA 1998; 95: 6355-6360
33. Croix BS, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW. Genes expressed in human tumor endothelium. Science 2000; 289: 1197-1202