메뉴 건너뛰기




Volumn 62, Issue 2, 2004, Pages 143-150

Role of SNP/haplotype map in gene discovery and drug development: An overview

Author keywords

Allele; Association; Gene; Haplotype; Linkage

Indexed keywords

CONTINUING EDUCATION; DISEASE PREDISPOSITION; DRUG DEVELOPMENT; DRUG EFFICACY; DRUG RESEARCH; GENE IDENTIFICATION; GENE MAPPING; HAPLOTYPE; HUMAN; HUMAN GENOME; PREDICTION; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 9644303301     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10377     Document Type: Review
Times cited : (13)

References (111)
  • 2
    • 0348218980 scopus 로고    scopus 로고
    • Neuropeptide gene polymorphisms and human behavioral disorders
    • Aiko I. 2003. Neuropeptide gene polymorphisms and human behavioral disorders. Nat Rev Drug Discov 2:986-998.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 986-998
    • Aiko, I.1
  • 3
    • 0344033839 scopus 로고    scopus 로고
    • Pharmacogenetic and pharmacogenomic studies: Impact on drug discovery and drug development
    • Alhenc-Gelas F, Parmentier L, Bisagni A. 2003. Pharmacogenetic and pharmacogenomic studies: impact on drug discovery and drug development. Therapie 58:275-282.
    • (2003) Therapie , vol.58 , pp. 275-282
    • Alhenc-Gelas, F.1    Parmentier, L.2    Bisagni, A.3
  • 4
    • 0141495008 scopus 로고    scopus 로고
    • Advances in pharmacogenetic prediction of antipsychiatric response
    • Arranz MJ, Kerwin RW. 2003. Advances in pharmacogenetic prediction of antipsychiatric response. Toxicology 192:33-35.
    • (2003) Toxicology , vol.192 , pp. 33-35
    • Arranz, M.J.1    Kerwin, R.W.2
  • 5
    • 0035986208 scopus 로고    scopus 로고
    • Discovery and utilization of haplotypes for pharmacogenetic studies of psychotropic drug response
    • Atbanasiou MC, Malhotra AK, Xu CB, Stephens JC. 2002. Discovery and utilization of haplotypes for pharmacogenetic studies of psychotropic drug response. Psychiatr Genet 12: 89-96.
    • (2002) Psychiatr Genet , vol.12 , pp. 89-96
    • Atbanasiou, M.C.1    Malhotra, A.K.2    Xu, C.B.3    Stephens, J.C.4
  • 6
    • 0034930262 scopus 로고    scopus 로고
    • The relative power of SNPs and haplotypes as genetic markers for association tests
    • Bader JS. 2001. The relative power of SNPs and haplotypes as genetic markers for association tests. Pharmacogenomics 2: 11-24.
    • (2001) Pharmacogenomics , vol.2 , pp. 11-24
    • Bader, J.S.1
  • 7
    • 0345731422 scopus 로고    scopus 로고
    • Clinical relevance of pharmacogenetics
    • Becquemont L. 2003. Clinical relevance of pharmacogenetics. Drug Metab Rev 35:277-285.
    • (2003) Drug Metab Rev , vol.35 , pp. 277-285
    • Becquemont, L.1
  • 8
    • 0036559958 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the proximal IFN-gamma promoter alters control of gene transcription
    • Bream JH, Ping A, Zhang X, Winkler C, Young HA. 2002. A single nucleotide polymorphism in the proximal IFN-gamma promoter alters control of gene transcription. Genes Immunity 3: 165-169.
    • (2002) Genes Immunity , vol.3 , pp. 165-169
    • Bream, J.H.1    Ping, A.2    Zhang, X.3    Winkler, C.4    Young, H.A.5
  • 9
    • 0035986209 scopus 로고    scopus 로고
    • Novel and alternate SNP and genetic technologies
    • Breen G. 2002. Novel and alternate SNP and genetic technologies. Psychiat Genet 12:83-83.
    • (2002) Psychiat Genet , vol.12 , pp. 83-83
    • Breen, G.1
  • 12
    • 0344091561 scopus 로고    scopus 로고
    • Additional SNPs and linkage disequilibrium analyses are necessary for whole genome association studies in humans
    • Carlson CS, Eberle MA, Rieder MJ, Smith JD, Kruglyak L, Nickerson DA. 2003. Additional SNPs and linkage disequilibrium analyses are necessary for whole genome association studies in humans. Nat Genet 33:518-521.
    • (2003) Nat Genet , vol.33 , pp. 518-521
    • Carlson, C.S.1    Eberle, M.A.2    Rieder, M.J.3    Smith, J.D.4    Kruglyak, L.5    Nickerson, D.A.6
  • 14
    • 0034799051 scopus 로고    scopus 로고
    • Candidate genes and single nucleotide polymorphisms (SNPs) in the study of human disease
    • Chanock S. 2001. Candidate genes and single nucleotide polymorphisms (SNPs) in the study of human disease. Dis Markers 17:89-98.
    • (2001) Dis Markers , vol.17 , pp. 89-98
    • Chanock, S.1
  • 15
    • 0033592988 scopus 로고    scopus 로고
    • Genetic epidemiology of single nucleotide polymorphisms
    • Collins A, Lonjou C, Morton NE. 1999. Genetic epidemiology of single nucleotide polymorphisms. Proc Natl Acad Sci USA 96:15173-15177.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 15173-15177
    • Collins, A.1    Lonjou, C.2    Morton, N.E.3
  • 17
    • 0037328994 scopus 로고    scopus 로고
    • Pharmacogenetics of the major polymorphic metabolizing enzymes
    • Daly AK. 2003. Pharmacogenetics of the major polymorphic metabolizing enzymes. Fundam Clin Pharmacol 17:27-41.
    • (2003) Fundam Clin Pharmacol , vol.17 , pp. 27-41
    • Daly, A.K.1
  • 19
    • 0035807591 scopus 로고    scopus 로고
    • The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization
    • Dishy V, Sofowora GG, Xie X-G, Kim RB, Byrne DW, Stein CM, Wood AJJ. 2001. The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization. N Engl J Med 345:1030-1035.
    • (2001) N Engl J Med , vol.345 , pp. 1030-1035
    • Dishy, V.1    Sofowora, G.G.2    Xie, X.-G.3    Kim, R.B.4    Byrne, D.W.5    Stein, C.M.6    Wood, A.J.J.7
  • 20
    • 0034883980 scopus 로고    scopus 로고
    • Flexible use of high-density oligonucleotide arrays for single nucleotide polymorphism discovery and validation
    • Dong SL, Wang E, Hsie L, Cao YX, Chen XG, Gingeras TR. 2001. Flexible use of high-density oligonucleotide arrays for single nucleotide polymorphism discovery and validation. Genome Res 11:1418-1424.
    • (2001) Genome Res , vol.11 , pp. 1418-1424
    • Dong, S.L.1    Wang, E.2    Hsie, L.3    Cao, Y.X.4    Chen, X.G.5    Gingeras, T.R.6
  • 21
    • 0034742201 scopus 로고    scopus 로고
    • A novel 5'-flanking region polymorphism of macrophage migration inhibitory factor is associated with systemic-onset juvenile idiopathic arthritis
    • Donn RP, Shelley E, Ollier WER, Thomson W. 2001. A novel 5'-flanking region polymorphism of macrophage migration inhibitory factor is associated with systemic-onset juvenile idiopathic arthritis. Arthritis Rhenmat 44:1782-1785.
    • (2001) Arthritis Rhenmat , vol.44 , pp. 1782-1785
    • Donn, R.P.1    Shelley, E.2    Ollier, W.E.R.3    Thomson, W.4
  • 22
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans WE, Relling MV. 1999. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286: 487-491.
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 23
    • 0036020644 scopus 로고    scopus 로고
    • Integrating pharmacogenomics into drug development
    • Ferentz AE. 2002. Integrating pharmacogenomics into drug development. Pharmacogenomics 3:453-467.
    • (2002) Pharmacogenomics , vol.3 , pp. 453-467
    • Ferentz, A.E.1
  • 25
    • 0042839486 scopus 로고    scopus 로고
    • Impact of molecular medicine on pathophysiology, medical practice and medical education
    • Gamulin S. 2003. Impact of molecular medicine on pathophysiology, medical practice and medical education. Croat Med J 44: 374-385.
    • (2003) Croat Med J , vol.44 , pp. 374-385
    • Gamulin, S.1
  • 27
    • 0035010640 scopus 로고    scopus 로고
    • Automation in genotyping of single nucleotide polymorphisms
    • Gut I. 2001. Automation in genotyping of single nucleotide polymorphisms. Hum Mutat 17:475-492.
    • (2001) Hum Mutat , vol.17 , pp. 475-492
    • Gut, I.1
  • 29
    • 0036713298 scopus 로고    scopus 로고
    • Advances in the development of genetic markers for the diagnosis of disease and drug response
    • Halapi E, Hakonarson H. 2002. Advances in the development of genetic markers for the diagnosis of disease and drug response. Expert Rev Mol Diagn 2:411-421.
    • (2002) Expert Rev Mol Diagn , vol.2 , pp. 411-421
    • Halapi, E.1    Hakonarson, H.2
  • 31
    • 0347526061 scopus 로고    scopus 로고
    • Human inter-individual DNA sequence variations in candidate genes, drug targets, the importance of haplotypes and pharmacogenomics
    • Hoehe MR, Timmermann B, Lehrach H. 2003. Human inter-individual DNA sequence variations in candidate genes, drug targets, the importance of haplotypes and pharmacogenomics. Curr Pharm Biotechnol 4:351-378.
    • (2003) Curr Pharm Biotechnol , vol.4 , pp. 351-378
    • Hoehe, M.R.1    Timmermann, B.2    Lehrach, H.3
  • 32
    • 0035988198 scopus 로고    scopus 로고
    • The common -675 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene is strongly associated with obesity
    • Hoffstedt J, Andersson LL, Persson L, Isaksson B, Arner P. 2002. The common -675 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene is strongly associated with obesity. Diabetologia 45:584-587.
    • (2002) Diabetologia , vol.45 , pp. 584-587
    • Hoffstedt, J.1    Andersson, L.L.2    Persson, L.3    Isaksson, B.4    Arner, P.5
  • 33
    • 0036221335 scopus 로고    scopus 로고
    • Human sex hormone binding globulin variants associated with hyperandrogenism and ovarian dysfuction
    • Hogeveen KN, Cousin P, Pugeat M, Dewailly D, Soudan B, Hammond GL. 2002. Human sex hormone binding globulin variants associated with hyperandrogenism and ovarian dysfuction. J Clin Invest 109:973-981.
    • (2002) J Clin Invest , vol.109 , pp. 973-981
    • Hogeveen, K.N.1    Cousin, P.2    Pugeat, M.3    Dewailly, D.4    Soudan, B.5    Hammond, G.L.6
  • 35
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap project
    • International HapMap Consortium. The International HapMap project. 2003. Nature 426:789-796.
    • (2003) Nature , vol.426 , pp. 789-796
  • 36
    • 0036924183 scopus 로고    scopus 로고
    • Personalized medicine
    • Jain KK. 2002. Personalized medicine. Curr Opin Mol Ther 4: 548-558.
    • (2002) Curr Opin Mol Ther , vol.4 , pp. 548-558
    • Jain, K.K.1
  • 37
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP 2D locus as a cause of ultrarapid metabolism of debrisoquine
    • Johansson I, Lundqvist E, Bertilsson L, Dahl ML, Sjoqvist F, Ingelman-Sundberg M. 1993. Inherited amplification of an active gene in the cytochrome P450 CYP 2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl. Acad. Sci USA 90:11825-11829.
    • (1993) Proc Natl. Acad. Sci USA , vol.90 , pp. 11825-11829
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3    Dahl, M.L.4    Sjoqvist, F.5    Ingelman-Sundberg, M.6
  • 39
    • 0035553086 scopus 로고    scopus 로고
    • Drug target pharmacogenomics: An overview
    • Johnson JA. 2001. Drug target pharmacogenomics: an overview. Am J Pharmacogenom 1:271-281.
    • (2001) Am J Pharmacogenom , vol.1 , pp. 271-281
    • Johnson, J.A.1
  • 42
    • 0346639205 scopus 로고    scopus 로고
    • Individualized medicine: Implementation of pharmacogenomic diagnostic in antidepressant drug treatment of major depressive disorders
    • Kirchheiner J, Bertilsson L, Brims H, Wolff A, Roots I, Bauer M. 2003. Individualized medicine: implementation of pharmacogenomic diagnostic in antidepressant drug treatment of major depressive disorders. Pharmacopsychiatry 36(Suppl):S235-S243.
    • (2003) Pharmacopsychiatry , vol.36 , Issue.SUPPL.
    • Kirchheiner, J.1    Bertilsson, L.2    Brims, H.3    Wolff, A.4    Roots, I.5    Bauer, M.6
  • 43
    • 0035179379 scopus 로고    scopus 로고
    • Association of a single nucleotide polymorphism in CPB2 encoding the thrombin-activable fibrinolysis inhibitor (TAFI) with blood pressure
    • Koschinsky ML, Boffa MB, Nesheim ME, Zinman B, Hanley AJG, Harris SB, Cao H, Hegele RA. 2001. Association of a single nucleotide polymorphism in CPB2 encoding the thrombin-activable fibrinolysis inhibitor (TAFI) with blood pressure. Clin Genet 60:345-349.
    • (2001) Clin Genet , vol.60 , pp. 345-349
    • Koschinsky, M.L.1    Boffa, M.B.2    Nesheim, M.E.3    Zinman, B.4    Hanley, A.J.G.5    Harris, S.B.6    Cao, H.7    Hegele, R.A.8
  • 45
    • 0033039497 scopus 로고    scopus 로고
    • Prospects for whole genome linkage disequilibrium mapping of common disease genes
    • Kruglyak L. 1999. Prospects for whole genome linkage disequilibrium mapping of common disease genes. Nat Genet 22: 139-144.
    • (1999) Nat Genet , vol.22 , pp. 139-144
    • Kruglyak, L.1
  • 46
    • 0035094764 scopus 로고    scopus 로고
    • Variation is the spice of life
    • Kruglyak L, Nickerson DA. 2001. Variation is the spice of life. Nat Genet 27:234-236.
    • (2001) Nat Genet , vol.27 , pp. 234-236
    • Kruglyak, L.1    Nickerson, D.A.2
  • 48
    • 0035776497 scopus 로고    scopus 로고
    • Methods for genotyping single nucleotide polymorphisms
    • Kwok P-Y. 2001. Methods for genotyping single nucleotide polymorphisms. Ann Rev Hum Genet 2:235-258.
    • (2001) Ann Rev Hum Genet , vol.2 , pp. 235-258
    • Kwok, P.-Y.1
  • 49
    • 0034830602 scopus 로고    scopus 로고
    • Application of SNP technologies in medicine: Lessons learned and future challenges
    • Lai E. 2001. Application of SNP technologies in medicine: lessons learned and future challenges. Genome Res 11:927-929.
    • (2001) Genome Res , vol.11 , pp. 927-929
    • Lai, E.1
  • 50
    • 0036843055 scopus 로고    scopus 로고
    • Medical application of haplotype-based SNP maps: Learning to walk before we run
    • Lai E, Bowman C, Bansal A, Hughes A, Mosteller M, Roses AD. 2002. Medical application of haplotype-based SNP maps: learning to walk before we run. Nat Genet 32:353.
    • (2002) Nat Genet , vol.32 , pp. 353
    • Lai, E.1    Bowman, C.2    Bansal, A.3    Hughes, A.4    Mosteller, M.5    Roses, A.D.6
  • 51
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients
    • Lazarou J, Pomeranz BH, Corey PN. 1998. Incidence of adverse drug reactions in hospitalized patients. JAMA 279:1200-1205.
    • (1998) JAMA , vol.279 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 52
    • 0035889904 scopus 로고    scopus 로고
    • A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of SP protein binding and enhances transcriptional activity
    • LeVan TD, Bloom JW, Bailey TJ, Karp CL, Halonen M, Martinez FD, Vercelli D. 2001. A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of SP protein binding and enhances transcriptional activity. J Immunol 167:5838-5844.
    • (2001) J Immunol , vol.167 , pp. 5838-5844
    • LeVan, T.D.1    Bloom, J.W.2    Bailey, T.J.3    Karp, C.L.4    Halonen, M.5    Martinez, F.D.6    Vercelli, D.7
  • 53
    • 0034434247 scopus 로고    scopus 로고
    • Investigations into the molecular effects of single nucleotide polymorphism
    • Lohrer HD, Tangen U. 2000. Investigations into the molecular effects of single nucleotide polymorphism. Pathobiology 68: 283-290.
    • (2000) Pathobiology , vol.68 , pp. 283-290
    • Lohrer, H.D.1    Tangen, U.2
  • 54
    • 0007293059 scopus 로고    scopus 로고
    • Ultrarapid metabolizers of debrisoquine: Characterization and PCR based detection of alleles with duplication of the CYP 2D6 gene
    • Lovlie R, Daly AK, Molven A, Idle JR, Steen VM. 1996. Ultrarapid metabolizers of debrisoquine: characterization and PCR based detection of alleles with duplication of the CYP 2D6 gene. FEBS Lett 392:30-34.
    • (1996) FEBS Lett , vol.392 , pp. 30-34
    • Lovlie, R.1    Daly, A.K.2    Molven, A.3    Idle, J.R.4    Steen, V.M.5
  • 60
    • 0034022213 scopus 로고    scopus 로고
    • The use of single nucleotide polymorphism maps in pharmacogenomics
    • McCarthy JJ, Hilfiker R. 2000. The use of single nucleotide polymorphism maps in pharmacogenomics. Nat Biotechnol 18:505-508.
    • (2000) Nat Biotechnol , vol.18 , pp. 505-508
    • McCarthy, J.J.1    Hilfiker, R.2
  • 62
    • 0037083663 scopus 로고    scopus 로고
    • High-throughput single nucleotide polymorphism genotyping by fluorescent competitive allele-specific polymerase chain reaction (SniPTag)
    • McClay JL, Sugden K, Koch HG, Higuchi S, Craig IW. 2002. High-throughput single nucleotide polymorphism genotyping by fluorescent competitive allele-specific polymerase chain reaction (SniPTag). Anal Biochem 301:200-206.
    • (2002) Anal Biochem , vol.301 , pp. 200-206
    • McClay, J.L.1    Sugden, K.2    Koch, H.G.3    Higuchi, S.4    Craig, I.W.5
  • 63
    • 0036216741 scopus 로고    scopus 로고
    • Molecular haplotyping of genomic DNA for multiple single nucleotide polymorphisms located kilobases apart using long-range polymerase chain reaction and intramolecular ligation
    • McDonald OG, Krynetski EY, Evans WE. 2002. Molecular haplotyping of genomic DNA for multiple single nucleotide polymorphisms located kilobases apart using long-range polymerase chain reaction and intramolecular ligation. Pharmacogenet 12:93-99.
    • (2002) Pharmacogenet , vol.12 , pp. 93-99
    • McDonald, O.G.1    Krynetski, E.Y.2    Evans, W.E.3
  • 64
    • 0037668882 scopus 로고    scopus 로고
    • Pharmacogenomics and drug response
    • Muller M. 2003. Pharmacogenomics and drug response. Int J Clin Pharmacol Ther 41:231-240.
    • (2003) Int J Clin Pharmacol Ther , vol.41 , pp. 231-240
    • Muller, M.1
  • 65
    • 0942279743 scopus 로고    scopus 로고
    • Association of tryptophan 2,3 dioxygenase gene polymorphism with autism
    • Nabi R, Serajee FJ, Chugani DC, Zhong H, Huq AH. 2004. Association of tryptophan 2,3 dioxygenase gene polymorphism with autism. Am J Med Genet 125B:63-68.
    • (2004) Am J Med Genet , vol.125 B , pp. 63-68
    • Nabi, R.1    Serajee, F.J.2    Chugani, D.C.3    Zhong, H.4    Huq, A.H.5
  • 67
    • 0347185032 scopus 로고    scopus 로고
    • Pharmacogenomics and individualized drug therapy: High expectations and disappointing achievements
    • Nebert DW, Jorge-Nebert L, Vesell ES. 2003. Pharmacogenomics and individualized drug therapy: high expectations and disappointing achievements. Am J Pharmacogenom 3:361-370.
    • (2003) Am J Pharmacogenom , vol.3 , pp. 361-370
    • Nebert, D.W.1    Jorge-Nebert, L.2    Vesell, E.S.3
  • 68
    • 0033965571 scopus 로고    scopus 로고
    • Estimation of population parameters and recombination rates from single nucleotide polymorphisms
    • Nielsen R. 2000. Estimation of population parameters and recombination rates from single nucleotide polymorphisms. Genetics 154:931-942.
    • (2000) Genetics , vol.154 , pp. 931-942
    • Nielsen, R.1
  • 69
    • 0034124688 scopus 로고    scopus 로고
    • Likelihood analysis of ongoing gene flow and historical association
    • Nielsen R, Slatkin M. 2000. Likelihood analysis of ongoing gene flow and historical association. Evolution 54:44-50.
    • (2000) Evolution , vol.54 , pp. 44-50
    • Nielsen, R.1    Slatkin, M.2
  • 70
    • 0347052803 scopus 로고    scopus 로고
    • Catecholo-methyltransferase polymorphism alters hypothalamic-pituitary- adrenal axis responses to naloxon: Preliminary report
    • Oswald LM, McCaul M, Choi L, Yang X, Wand GS. 2004. Catecholo- methyltransferase polymorphism alters hypothalamic-pituitary-adrenal axis responses to naloxon: preliminary report. Biol Psychiatry 55:102-105.
    • (2004) Biol Psychiatry , vol.55 , pp. 102-105
    • Oswald, L.M.1    McCaul, M.2    Choi, L.3    Yang, X.4    Wand, G.S.5
  • 73
    • 0035991108 scopus 로고    scopus 로고
    • Association of G33A polymorphism in the thrombomodulin gene with myocardial infarction
    • Park HY, Nabika T, Jang Y, Kwon HN, Cho SY, Masuda J. 2002. Association of G33A polymorphism in the thrombomodulin gene with myocardial infarction. Hypertension Res 25: 384-394.
    • (2002) Hypertension Res , vol.25 , pp. 384-394
    • Park, H.Y.1    Nabika, T.2    Jang, Y.3    Kwon, H.N.4    Cho, S.Y.5    Masuda, J.6
  • 74
    • 0035861049 scopus 로고    scopus 로고
    • Potential role of pharmacogenomics in reducing adverse drug reactions: A systematic review
    • Phillips KA, Veenstra DL, Oren E, Lee JK, Sadee W. 2001. Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review. JAMA 286:2270-2279.
    • (2001) JAMA , vol.286 , pp. 2270-2279
    • Phillips, K.A.1    Veenstra, D.L.2    Oren, E.3    Lee, J.K.4    Sadee, W.5
  • 75
    • 0035369825 scopus 로고    scopus 로고
    • Gentic susceptibility to drug reactions
    • Pirmohamed M, Park BK. 2001. Gentic susceptibility to drug reactions. Trends Pharmacol Sci 22:298-305.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 298-305
    • Pirmohamed, M.1    Park, B.K.2
  • 76
  • 78
    • 16744365916 scopus 로고    scopus 로고
    • L-RCA (Ligation-rolling circle amplification): A general method for genotyping of single nucleotide polymorphisms (SNPs)
    • Qi XQ, Bakht S, Devos KM, Gale MD, Osbourn A. 2001. L-RCA (Ligation-rolling circle amplification): a general method for genotyping of single nucleotide polymorphisms (SNPs). Nucleic Acids Res 29:U68-U74.
    • (2001) Nucleic Acids Res , vol.29
    • Qi, X.Q.1    Bakht, S.2    Devos, K.M.3    Gale, M.D.4    Osbourn, A.5
  • 81
    • 0034139510 scopus 로고    scopus 로고
    • The use of single nucleotide polymorphism in the isolation of common disease gene
    • Riley J-H, Allan CJ, Lai E, Roses A. 2000. The use of single nucleotide polymorphism in the isolation of common disease gene. Pharmacogenomics 1:39-47.
    • (2000) Pharmacogenomics , vol.1 , pp. 39-47
    • Riley, J.-H.1    Allan, C.J.2    Lai, E.3    Roses, A.4
  • 82
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K. 1996. The future of genetic studies of complex human diseases. Science 273:1516-1517.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 83
    • 0036633359 scopus 로고    scopus 로고
    • Genome-based pharmacogenetics and the pharmaceutical industry
    • Roses AD. 2002. Genome-based pharmacogenetics and the pharmaceutical industry. Nat Rev Drug Discov 1:541-549.
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 541-549
    • Roses, A.D.1
  • 84
    • 1842848834 scopus 로고    scopus 로고
    • Integration of molecular diagnostics with thearapeutics: Implications of drug discovery and patient care
    • Ross JS, Ginsburg GS. 2002. Integration of molecular diagnostics with thearapeutics: implications of drug discovery and patient care. Expert Rev Mol Diagn 2:531-541.
    • (2002) Expert Rev Mol Diagn , vol.2 , pp. 531-541
    • Ross, J.S.1    Ginsburg, G.S.2
  • 85
    • 0031038038 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 variants in a Caucasian population: Allelic frequency and phenotypic consequences
    • Sachse C, Brockmoller J, Bauer S, Roots I. 1997. Cytochrome P450 2D6 variants in a Caucasian population: allelic frequency and phenotypic consequences. Am J Hum Genet 60:284-295.
    • (1997) Am J Hum Genet , vol.60 , pp. 284-295
    • Sachse, C.1    Brockmoller, J.2    Bauer, S.3    Roots, I.4
  • 87
    • 0036594372 scopus 로고    scopus 로고
    • The challenge of using SNPs in the understanding and treatment of disease
    • Schifreen RS, Storts DR, Buller AM. 2002. The challenge of using SNPs in the understanding and treatment of disease. Biotechniques 32:S14-S21.
    • (2002) Biotechniques , vol.32
    • Schifreen, R.S.1    Storts, D.R.2    Buller, A.M.3
  • 88
    • 1042280308 scopus 로고    scopus 로고
    • Defining haplotype blocks and tag single nucleotide polymorphisms in the human genome
    • Schulze TG, Zhang K, Chen Y-S, Akula N, Sun F, McMohan FJ. 2004. Defining haplotype blocks and tag single nucleotide polymorphisms in the human genome. Hum Mol Genet 13: 335-342.
    • (2004) Hum Mol Genet , vol.13 , pp. 335-342
    • Schulze, T.G.1    Zhang, K.2    Chen, Y.-S.3    Akula, N.4    Sun, F.5    McMohan, F.J.6
  • 89
    • 0036955891 scopus 로고    scopus 로고
    • SNP alleles in human disease and evolution
    • Shastry BS. 2002. SNP alleles in human disease and evolution. J Hum Genet 47:561-566.
    • (2002) J Hum Genet , vol.47 , pp. 561-566
    • Shastry, B.S.1
  • 90
    • 3442891124 scopus 로고    scopus 로고
    • SNPs and haplotypes: Genetic markers for disease and drug response
    • Shastry BS. 2003. SNPs and haplotypes: genetic markers for disease and drug response. Int J Mol Med 11:379-382.
    • (2003) Int J Mol Med , vol.11 , pp. 379-382
    • Shastry, B.S.1
  • 91
    • 0037399407 scopus 로고    scopus 로고
    • Mechanisms of antiepileptic drug resistance
    • Sisodiya SM. 2003. Mechanisms of antiepileptic drug resistance. Curr Opin Neurol 16:197-201.
    • (2003) Curr Opin Neurol , vol.16 , pp. 197-201
    • Sisodiya, S.M.1
  • 93
    • 0038781903 scopus 로고    scopus 로고
    • Neutral substitution occurs at a faster rate in exons than in non-coding DNA in primate genome
    • Subramanian S, Kumar S. 2003. Neutral substitution occurs at a faster rate in exons than in non-coding DNA in primate genome. Genome Res 13:838-844.
    • (2003) Genome Res , vol.13 , pp. 838-844
    • Subramanian, S.1    Kumar, S.2
  • 96
    • 0035052163 scopus 로고    scopus 로고
    • Association of fibrillin-1 single nucleotide polymorphism haplotypes with systemic sclerosis in Choctaw and Japanese populations
    • Tan F-K, Wang N, Kuwana M, Chakraborty R, Bona CA, Milewicz DM, Arnett FC. 2001. Association of fibrillin-1 single nucleotide polymorphism haplotypes with systemic sclerosis in Choctaw and Japanese populations. Arthritis Rheumat 44:893-901.
    • (2001) Arthritis Rheumat , vol.44 , pp. 893-901
    • Tan, F.-K.1    Wang, N.2    Kuwana, M.3    Chakraborty, R.4    Bona, C.A.5    Milewicz, D.M.6    Arnett, F.C.7
  • 97
    • 0347136012 scopus 로고    scopus 로고
    • Applications of polymorphisms and pharmacogenomics in obstetrics and gynecology
    • Tempfer CB, Schneeberger C, Huber JC. 2004. Applications of polymorphisms and pharmacogenomics in obstetrics and gynecology. Pharmacogenomics 5:57-65.
    • (2004) Pharmacogenomics , vol.5 , pp. 57-65
    • Tempfer, C.B.1    Schneeberger, C.2    Huber, J.C.3
  • 98
    • 0036399958 scopus 로고    scopus 로고
    • Pharmacogenetics, pharmacogenomics and cardiovascular therapeutics: The way forward
    • Terra SG, Johnson JA. 2002. Pharmacogenetics, pharmacogenomics and cardiovascular therapeutics: the way forward. Am J Cardiovasc Drugs 2:287-296.
    • (2002) Am J Cardiovasc Drugs , vol.2 , pp. 287-296
    • Terra, S.G.1    Johnson, J.A.2
  • 101
    • 0038639109 scopus 로고    scopus 로고
    • Association of E-cadherin gene 3'- UTR C/T polymorphism with calcium oxalate stone disease
    • Tsai FJ, Wu HC, Che HY, Lu HF, Hsu CD, Chen WC. 2003. Association of E-cadherin gene 3'- UTR C/T polymorphism with calcium oxalate stone disease. Urol Int 70:278-281.
    • (2003) Urol Int , vol.70 , pp. 278-281
    • Tsai, F.J.1    Wu, H.C.2    Che, H.Y.3    Lu, H.F.4    Hsu, C.D.5    Chen, W.C.6
  • 104
    • 1342332259 scopus 로고    scopus 로고
    • Protecting communities in pharmacogenetic and pharmacogenomic research
    • Weijer C, Miller PB. 2004. Protecting communities in pharmacogenetic and pharmacogenomic research. Pharmacogenomics J 4:9-16.
    • (2004) Pharmacogenomics J , vol.4 , pp. 9-16
    • Weijer, C.1    Miller, P.B.2
  • 108
    • 0035688823 scopus 로고    scopus 로고
    • Single nucleotide polymorphism analysis using a bacterial magnetic peptide microarray
    • Yoshino T, Takeyama H, Matsunaga T. 2001. Single nucleotide polymorphism analysis using a bacterial magnetic peptide microarray. Electrochemistry 69:1008-1012.
    • (2001) Electrochemistry , vol.69 , pp. 1008-1012
    • Yoshino, T.1    Takeyama, H.2    Matsunaga, T.3
  • 109
    • 1442327757 scopus 로고    scopus 로고
    • Common variants in glutamine fructose-6-phosphate amidotransferase 2 (GFPT 2) gene are associated with type II diabetes, diabetic nephropathy and increased GFPT 2 mRNA level
    • Zhang H, Jia Y, Cooper JJ, Hale T, Zhang Z, Elbein SC. 2004. Common variants in glutamine fructose-6-phosphate amidotransferase 2 (GFPT 2) gene are associated with type II diabetes, diabetic nephropathy and increased GFPT 2 mRNA level. J Clin Endocrinol Metab 89:748-755.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 748-755
    • Zhang, H.1    Jia, Y.2    Cooper, J.J.3    Hale, T.4    Zhang, Z.5    Elbein, S.C.6
  • 110
    • 0038406155 scopus 로고    scopus 로고
    • A method for the assessment of disease association with single nucleotide polymorphism haplotypes and environmental variables in case-control studies
    • Zhao LP, Li SYS, Khalid N. 2003. A method for the assessment of disease association with single nucleotide polymorphism haplotypes and environmental variables in case-control studies. Am J Hum Genet 72:1231-1250.
    • (2003) Am J Hum Genet , vol.72 , pp. 1231-1250
    • Zhao, L.P.1    Li, S.Y.S.2    Khalid, N.3
  • 111
    • 0035503537 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances lung cancer susceptibility
    • Zhu Y, Spitz MR, Lei L, Mills GB, Wu XF. 2001. A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances lung cancer susceptibility. Cancer Res 61: 7825-7829.
    • (2001) Cancer Res , vol.61 , pp. 7825-7829
    • Zhu, Y.1    Spitz, M.R.2    Lei, L.3    Mills, G.B.4    Wu, X.F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.