Association of a novel single nucleotide polymorphism of the prostacyclin synthase gene with myocardial infarction

American Heart Journal

Volumn 143, Issue 5, 2002, Pages 797-801

  Nakayama, Tomohiro ^a   Soma, Masayoshi ^b   Saito, Satoshi ^b   Honye, Junko ^b   Yajima, Junji ^b   Rahmutula, Dolkun ^b   Kaneko, Yukie ^b   Sato, Mikano ^b   Uwabo, Jiro ^b   Aoi, Noriko ^b   Kosuge, Kotoko ^b   Kunimoto, Masako ^b   Kanmatsuse, Katsuo ^b   Kokubun, Shinichiro ^c  

^a Advanced Medical Research Center   (Japan)

^b NIHON UNIVERSITY   (Japan)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

PROSTACYCLIN SYNTHASE;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; GENETIC SUSCEPTIBILITY; HEART INFARCTION; HUMAN; JAPAN; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 0036267504     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1067/mhj.2002.122171     Document Type: Article

References (22)

1. Genetic susceptibility to death from coronary heart disease in a study of twins
2. Genetic-epidemiologlc study of early-onset ischemic heart disease
3. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction
4. Apolipoprotein 4 homozygosity young men with coronary heart disease
5. A polymorphism of a platelet glycoprotein receptor as an inherited risk factor for coronary thrombosis
6. Platelet activation mechanisms and markers in arterial thrombosis
7. Prevention of myocardial infarction and stroke by aspirin: Different mechanisms? Different dosage?
8. Platelet hyperreactivity and prognosis in survivors of myocardial infarction
9. On the formation and effects of thromboxane A2 in human platelets
10. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
11. Cytokines and endothelial cell biology
12. The prostacyclin-thromboxane A2 balance: Pathophysiological and therapeutic implications
13. Clinical implications of prostaglandin and thromboxane A2 formation
14. Human gene encoding prostacyclin synthase (PTGIS): Genomic organization, chromosomal localization, and promoter activity
15. Organization of the human prostacyclin synthase gene
16. Association of 5′ upstream promoter region of prostacyclin synthase gene variant with cerebral infarction
17. Familial dyslipidemic hypertension: Evidence from 58 Utah families for syndrome present in approximately 12% of patients with essential hypertension
18. Isolation of the 5′flanking region of genes by thermal asymmetric, interlaced polymerase chain reaction
19. Platelet function and antiaggregant therapy in ischemic stroke
20. Prostacyclin in the cardiovascular system in health and disease
21. Nonsense mutation of prostacyclin synthase gene in a family
22. Polymorphism of the promoter region of prostacyclin synthase gene is not associated with essential hypertension