Evidence for a single nucleotide polymorphism in the KCNQ1 potassium channel that underlies susceptibility to life-threatening arrhythmias

Journal of Cardiovascular Electrophysiology

Volumn 12, Issue 11, 2001, Pages 1223-1229

  Kubota, Tomoyuki ^a   Horie, Minoru ^a,b   Takano, Makoto ^b,c   Yoshida, Hidetada ^a   Takenaka, Kotoe ^a   Watanabe, Eiichi ^c,d   Tsuchiya, Takeshi ^e   Otani, Hideo ^a   Sasayama, Shigetake ^a  

^a Departments of Metabolic Medicine   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c Fujita Health University School of Medicine ^*

^d FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e SAISEIKAI KUMAMOTO HOSPITAL   (Japan)

Author keywords

KCNE1; KCNQ1; Long QT syndrome; Molecular diagnosis; Single nucleotide polymorphism

Indexed keywords

GENE PRODUCT; POTASSIUM CHANNEL; PROTEIN KCNE1; PROTEIN KCNQ1; UNCLASSIFIED DRUG;

ADULT; AGED; AMINO ACID SUBSTITUTION; ARRHYTHMOGENESIS; ARTICLE; BRADYCARDIA; CLINICAL ARTICLE; FEMALE; GENE MUTATION; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; HEART ARRHYTHMIA; HETEROZYGOTE; HUMAN; HYPOKALEMIA; JAPAN; KCNQ1 GENE; LONG QT SYNDROME; MUTATOR GENE; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; SINGLE STRAND CONFORMATION POLYMORPHISM; VOLTAGE CLAMP;

EID: 0035193284     PISSN: 10453873     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1540-8167.2001.01223.x     Document Type: Article

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