메뉴 건너뛰기




Volumn 15, Issue 6, 2004, Pages 615-622

Carbohydrate diversity: Synthesis of glycoconjugates and complex carbohydrates

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL PROCESSES; GLYCOCONJUGATES; GLYCOPROTEINS; OLIGOSACCHARIDES;

EID: 9244224089     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.copbio.2004.10.001     Document Type: Review
Times cited : (93)

References (52)
  • 1
    • 0036462604 scopus 로고    scopus 로고
    • Synthesis of glycoproteins
    • B.G. Davis Synthesis of glycoproteins Chem Rev 102 2002 579 601
    • (2002) Chem Rev , vol.102 , pp. 579-601
    • Davis, B.G.1
  • 2
    • 0345255892 scopus 로고    scopus 로고
    • Recent developments in the synthesis and discovery of oligosaccharides and glycoconjugates for the treatment of disease
    • D. Macmillan, and A.M. Daines Recent developments in the synthesis and discovery of oligosaccharides and glycoconjugates for the treatment of disease Curr Med Chem 10 2003 2733 2773
    • (2003) Curr Med Chem , vol.10 , pp. 2733-2773
    • MacMillan, D.1    Daines, A.M.2
  • 5
    • 0035936861 scopus 로고    scopus 로고
    • Automated solid-phase synthesis of oligosaccharides
    • O.J. Plante, E.R. Palmacci, and P.H. Seeberger Automated solid-phase synthesis of oligosaccharides Science 291 2001 1523 1527 The authors describe the first automated solid-phase oligosaccharide synthesizer for the preparation of linear and branched structures up to dodecasaccharides. New glycosylating agents, linker, coupling cycles and the use of high-resolution magic angle spinning NMR to follow reactions on polymer support are discussed.
    • (2001) Science , vol.291 , pp. 1523-1527
    • Plante, O.J.1    Palmacci, E.R.2    Seeberger, P.H.3
  • 6
    • 0037463417 scopus 로고    scopus 로고
    • A short synthesis of the trisaccharide building block of the N-linked glycans
    • V.Y. Dudkin, and D. Crich A short synthesis of the trisaccharide building block of the N-linked glycans Tetrahedron Lett 44 2003 1787 1789
    • (2003) Tetrahedron Lett , vol.44 , pp. 1787-1789
    • Dudkin, V.Y.1    Crich, D.2
  • 7
    • 0037451438 scopus 로고    scopus 로고
    • Synthesis of a core trisaccharide as a versatile building block for N-glycans and glycoconjugates
    • C. Unverzagt Synthesis of a core trisaccharide as a versatile building block for N-glycans and glycoconjugates Chem Eur J 9 2003 1369 1376
    • (2003) Chem Eur J , vol.9 , pp. 1369-1376
    • Unverzagt, C.1
  • 8
    • 0037463507 scopus 로고    scopus 로고
    • A concise route to the core pentasaccharide of N-linked glycoproteins
    • V.Y. Dudkin, J.S. Miller, and S.J. Danishefsky A concise route to the core pentasaccharide of N-linked glycoproteins Tetrahedron Lett 44 2003 1791 1793
    • (2003) Tetrahedron Lett , vol.44 , pp. 1791-1793
    • Dudkin, V.Y.1    Miller, J.S.2    Danishefsky, S.J.3
  • 9
    • 0037011298 scopus 로고    scopus 로고
    • Efficient solid-phase synthesis of a complex, branched N-glycan hexasaccharide: Use of a novel linker and temporary-protecting-group pattern
    • X.Y. Wu, M. Grathwohl, and R.R. Schmidt Efficient solid-phase synthesis of a complex, branched N-glycan hexasaccharide: use of a novel linker and temporary-protecting-group pattern Angew Chem Int Edit 41 2002 4489 4493
    • (2002) Angew Chem Int Edit , vol.41 , pp. 4489-4493
    • Wu, X.Y.1    Grathwohl, M.2    Schmidt, R.R.3
  • 10
    • 0347411058 scopus 로고    scopus 로고
    • Automated synthesis of a protected N-linked glycoprotein core pentasaccharide
    • D.M. Ratner, E.R. Swanson, and P.H. Seeberger Automated synthesis of a protected N-linked glycoprotein core pentasaccharide Org Lett 5 2003 4717 4720
    • (2003) Org Lett , vol.5 , pp. 4717-4720
    • Ratner, D.M.1    Swanson, E.R.2    Seeberger, P.H.3
  • 11
    • 0141633603 scopus 로고    scopus 로고
    • Highly branched oligosaccharides: A general strategy for the synthesis of multiantennary N-glycans with a bisected motif
    • H. Weiss, and C. Unverzagt Highly branched oligosaccharides: a general strategy for the synthesis of multiantennary N-glycans with a bisected motif Angew Chem Int Edit 42 2003 4261 4263
    • (2003) Angew Chem Int Edit , vol.42 , pp. 4261-4263
    • Weiss, H.1    Unverzagt, C.2
  • 12
    • 0037122782 scopus 로고    scopus 로고
    • Structure-activity profiles of complex biantennary glycans with core fucosylation and with/without additional α2,3/α2,6 sialylation: Synthesis of neoglycoproteins and their properties in lectin assays, cell binding, and organ uptake
    • C. Unverzagt, S. Andre, J. Seifert, S. Kojima, C. Fink, G. Srikrishna, H. Freeze, K. Kayser, and H.J. Gabius Structure-activity profiles of complex biantennary glycans with core fucosylation and with/without additional α2,3/α2,6 sialylation: synthesis of neoglycoproteins and their properties in lectin assays, cell binding, and organ uptake J Med Chem 45 2002 478 491
    • (2002) J Med Chem , vol.45 , pp. 478-491
    • Unverzagt, C.1    Andre, S.2    Seifert, J.3    Kojima, S.4    Fink, C.5    Srikrishna, G.6    Freeze, H.7    Kayser, K.8    Gabius, H.J.9
  • 13
    • 0037112587 scopus 로고    scopus 로고
    • Enzymatic elongation of the LEC14 antigen generates a β-1,2 arm on N-glycans
    • I. Prahl, and C. Unverzagt Enzymatic elongation of the LEC14 antigen generates a β-1,2 arm on N-glycans Angew Chem Int Edit 41 2002 4259 4262
    • (2002) Angew Chem Int Edit , vol.41 , pp. 4259-4262
    • Prahl, I.1    Unverzagt, C.2
  • 14
    • 0037467411 scopus 로고    scopus 로고
    • Synthesis of monoglucosylated high-mannose-type dodecasaccharide, a putative ligand for molecular chaperone, calnexin, and calreticurin
    • I. Matsuo, M. Wada, S. Manabe, Y. Yamaguchi, K. Otake, K. Kato, and Y. Ito Synthesis of monoglucosylated high-mannose-type dodecasaccharide, a putative ligand for molecular chaperone, calnexin, and calreticurin J Am Chem Soc 125 2003 3402 3403
    • (2003) J Am Chem Soc , vol.125 , pp. 3402-3403
    • Matsuo, I.1    Wada, M.2    Manabe, S.3    Yamaguchi, Y.4    Otake, K.5    Kato, K.6    Ito, Y.7
  • 15
    • 1542504611 scopus 로고    scopus 로고
    • Synthesis of an octamannosyled glycan chain, the key oligosaccharide structure in ER-associated degradation
    • I. Matsuo, and Y. Ito Synthesis of an octamannosyled glycan chain, the key oligosaccharide structure in ER-associated degradation Carbohydr Res 338 2003 2163 2168
    • (2003) Carbohydr Res , vol.338 , pp. 2163-2168
    • Matsuo, I.1    Ito, Y.2
  • 16
    • 1842690074 scopus 로고    scopus 로고
    • Tight binding ligand approach to oligosaccharide-grafted protein
    • K. Totani, I. Matsuo, and Y. Ito Tight binding ligand approach to oligosaccharide-grafted protein Bioorg Med Chem Lett 14 2004 2285 2289
    • (2004) Bioorg Med Chem Lett , vol.14 , pp. 2285-2289
    • Totani, K.1    Matsuo, I.2    Ito, Y.3
  • 17
    • 0037474648 scopus 로고    scopus 로고
    • The first synthesis of peptide thioester carrying N-linked core pentasaccharide through modified Fmoc thioester preparation: Synthesis of an N-glycosylated Ig domain of emmprin
    • H. Hojo, E. Haginoya, Y. Matsumoto, Y. Nakahara, K. Nabeshima, B.P. Toole, and Y. Watanabe The first synthesis of peptide thioester carrying N-linked core pentasaccharide through modified Fmoc thioester preparation: synthesis of an N-glycosylated Ig domain of emmprin Tetrahedron Lett 44 2003 2961 2964
    • (2003) Tetrahedron Lett , vol.44 , pp. 2961-2964
    • Hojo, H.1    Haginoya, E.2    Matsumoto, Y.3    Nakahara, Y.4    Nabeshima, K.5    Toole, B.P.6    Watanabe, Y.7
  • 19
    • 0242576156 scopus 로고    scopus 로고
    • Chemical synthesis of CD52 glycopeptides containing the acid-labile fucosyl linkage
    • N. Shao, J. Xue, and Z.W. Guo Chemical synthesis of CD52 glycopeptides containing the acid-labile fucosyl linkage J Org Chem 68 2003 9003 9011
    • (2003) J Org Chem , vol.68 , pp. 9003-9011
    • Shao, N.1    Xue, J.2    Guo, Z.W.3
  • 20
    • 0038627500 scopus 로고    scopus 로고
    • Chemoselective ligation applied to the synthesis of a biantennary N-linked glycoform of CD52
    • M.R. Pratt, and C.R. Bertozzi Chemoselective ligation applied to the synthesis of a biantennary N-linked glycoform of CD52 J Am Chem Soc 125 2003 6149 6159
    • (2003) J Am Chem Soc , vol.125 , pp. 6149-6159
    • Pratt, M.R.1    Bertozzi, C.R.2
  • 21
    • 1642453589 scopus 로고    scopus 로고
    • Chemical synthesis of normal and transformed PSA glycopeptides
    • V.Y. Dudkin, J.S. Miller, and S.J. Danishefsky Chemical synthesis of normal and transformed PSA glycopeptides J Am Chem Soc 126 2004 736 738 A universal method for the preparation of N-linked glycans from a common precursor has been established and efficiently applied to the synthesis of normal and transformed PSA fragments.
    • (2004) J Am Chem Soc , vol.126 , pp. 736-738
    • Dudkin, V.Y.1    Miller, J.S.2    Danishefsky, S.J.3
  • 23
    • 0036195024 scopus 로고    scopus 로고
    • A linear synthesis of branched high-mannose oligosaccharides from the HIV-1 viral surface envelope glycoprotein gp120
    • D.M. Ratner, O.J. Plante, and P.H. Seeberger A linear synthesis of branched high-mannose oligosaccharides from the HIV-1 viral surface envelope glycoprotein gp120 Eur J Org Chem 2002 826 833
    • (2002) Eur J Org Chem , pp. 826-833
    • Ratner, D.M.1    Plante, O.J.2    Seeberger, P.H.3
  • 25
    • 2542591183 scopus 로고    scopus 로고
    • In pursuit of carbohydrate-based HIV vaccines, Part 1: The total synthesis of hybrid-type gp120 fragments
    • M. Mandal, V.Y. Dudkin, X.D. Geng, and S. Danishefsky In pursuit of carbohydrate-based HIV vaccines, Part 1: The total synthesis of hybrid-type gp120 fragments Angew Chem Int Edit 43 2004 2557 2561 The first chemical synthesis of mature hybrid type HIV gp120 glycopeptide fragments is reported, which may serve as anti-HIV vaccines.
    • (2004) Angew Chem Int Edit , vol.43 , pp. 2557-2561
    • Mandal, M.1    Dudkin, V.Y.2    Geng, X.D.3    Danishefsky, S.4
  • 26
    • 2542592700 scopus 로고    scopus 로고
    • In pursuit of carbohydrate-based HIV vaccines, Part 2: The total synthesis of high-mannose-type gp120 fragments-evaluation of strategies directed to maximal convergence
    • X.D. Geng, V.Y. Dudkin, M. Mandal, and S.J. Danishefsky In pursuit of carbohydrate-based HIV vaccines, Part 2: The total synthesis of high-mannose-type gp120 fragments-evaluation of strategies directed to maximal convergence Angew Chem Int Edit 43 2004 2562 2565 The first chemical synthesis of high-mannose type HIV gp120 glycopeptide fragments has been achieved using either a 'layered' or a 'block' assembly oligosaccharide approach. The glycans were then linked to gp120 peptide fragments by direct aspartylation.
    • (2004) Angew Chem Int Edit , vol.43 , pp. 2562-2565
    • Geng, X.D.1    Dudkin, V.Y.2    Mandal, M.3    Danishefsky, S.J.4
  • 27
    • 2542548800 scopus 로고    scopus 로고
    • Toward fully synthetic glycoproteins by ultimately convergent routes: A solution to a long-standing problem
    • J.D. Warren, J.S. Miller, S.J. Keding, and S.J. Danishefsky Toward fully synthetic glycoproteins by ultimately convergent routes: a solution to a long-standing problem J Am Chem Soc 126 2004 6576 6578
    • (2004) J Am Chem Soc , vol.126 , pp. 6576-6578
    • Warren, J.D.1    Miller, J.S.2    Keding, S.J.3    Danishefsky, S.J.4
  • 28
    • 0037811533 scopus 로고    scopus 로고
    • Synthetic glycopeptides for the development of antitumour vaccines
    • S. Dziadek, C.G. Espinola, and H. Kunz Synthetic glycopeptides for the development of antitumour vaccines Aust J Chem 56 2003 519 543
    • (2003) Aust J Chem , vol.56 , pp. 519-543
    • Dziadek, S.1    Espinola, C.G.2    Kunz, H.3
  • 29
    • 2142758182 scopus 로고    scopus 로고
    • Synthesis of tumor-associated glycopeptide antigens for the development of tumor-selective vaccines
    • S. Dziadek, and H. Kunz Synthesis of tumor-associated glycopeptide antigens for the development of tumor-selective vaccines Chem Rec 3 2004 308 321
    • (2004) Chem Rec , vol.3 , pp. 308-321
    • Dziadek, S.1    Kunz, H.2
  • 30
    • 0036591493 scopus 로고    scopus 로고
    • Recent advances in the chemical synthesis of mucin-like glycoproteins
    • L.A. Marcaurelle, and C.R. Bertozzi Recent advances in the chemical synthesis of mucin-like glycoproteins Glycobiology 12 2002 69R 77R
    • (2002) Glycobiology , vol.12
    • Marcaurelle, L.A.1    Bertozzi, C.R.2
  • 31
    • 0036332863 scopus 로고    scopus 로고
    • Synthesis of tumor-associated glycopeptide antigens
    • C. Brocke, and H. Kunz Synthesis of tumor-associated glycopeptide antigens Bioorg Med Chem 10 2002 3085 3112 A good review summarizing the synthesis of tumour-associated glycopeptide antigens.
    • (2002) Bioorg Med Chem , vol.10 , pp. 3085-3112
    • Brocke, C.1    Kunz, H.2
  • 32
    • 0037064492 scopus 로고    scopus 로고
    • Preparation of core 2 type tetrasaccharide carrying decapeptide by benzyl protection-based solid-phase synthesis strategy
    • Y. Takano, M. Habiro, M. Someya, H. Hojo, and Y. Nakahara Preparation of core 2 type tetrasaccharide carrying decapeptide by benzyl protection-based solid-phase synthesis strategy Tetrahedron Lett 43 2002 8395 8399
    • (2002) Tetrahedron Lett , vol.43 , pp. 8395-8399
    • Takano, Y.1    Habiro, M.2    Someya, M.3    Hojo, H.4    Nakahara, Y.5
  • 33
    • 1642369400 scopus 로고    scopus 로고
    • Synthetic tumor-associated glycopeptide antigens from the tandem repeat sequence of the epithelial mucin MUC4
    • C. Brocke, and H. Kunz Synthetic tumor-associated glycopeptide antigens from the tandem repeat sequence of the epithelial mucin MUC4 Synthesis 2004 525 542
    • (2004) Synthesis , pp. 525-542
    • Brocke, C.1    Kunz, H.2
  • 34
    • 1642456653 scopus 로고    scopus 로고
    • Efficient synthesis of core 2 class glycosyl amino acids by one-pot glycosylation approach
    • H. Tanaka, M. Adachi, and T. Takahashi Efficient synthesis of core 2 class glycosyl amino acids by one-pot glycosylation approach Tetrahedron Lett 45 2004 1433 1436
    • (2004) Tetrahedron Lett , vol.45 , pp. 1433-1436
    • Tanaka, H.1    Adachi, M.2    Takahashi, T.3
  • 35
    • 0141594749 scopus 로고    scopus 로고
    • Convergent total syntheses of oligosaccharides by one-pot sequential stereoselective glycosylations
    • T. Hashihayata, K. Ikegai, K. Takeuchi, H. Jona, and T. Mukaiyama Convergent total syntheses of oligosaccharides by one-pot sequential stereoselective glycosylations Bull Chem Soc Jpn 76 2003 1829 1848
    • (2003) Bull Chem Soc Jpn , vol.76 , pp. 1829-1848
    • Hashihayata, T.1    Ikegai, K.2    Takeuchi, K.3    Jona, H.4    Mukaiyama, T.5
  • 36
    • 0037157167 scopus 로고    scopus 로고
    • Efficient chemoenzymatic synthesis of O-linked sialyl oligosaccharides
    • O. Blixt, K. Allin, L. Pereira, A. Datta, and J.C. Paulson Efficient chemoenzymatic synthesis of O-linked sialyl oligosaccharides J Am Chem Soc 124 2002 5739 5746
    • (2002) J Am Chem Soc , vol.124 , pp. 5739-5746
    • Blixt, O.1    Allin, K.2    Pereira, L.3    Datta, A.4    Paulson, J.C.5
  • 37
    • 0035820048 scopus 로고    scopus 로고
    • Pursuit of optimal carbohydrate-based anticancer vaccines: Preparation of a multiantigenic unimolecular glycopeptide containing the Tn, MBr1, and Lewis(y) antigens
    • J.R. Allen, C.R. Harris, and S.J. Danishefsky Pursuit of optimal carbohydrate-based anticancer vaccines: preparation of a multiantigenic unimolecular glycopeptide containing the Tn, MBr1, and Lewis(y) antigens J Am Chem Soc 123 2001 1890 1897
    • (2001) J Am Chem Soc , vol.123 , pp. 1890-1897
    • Allen, J.R.1    Harris, C.R.2    Danishefsky, S.J.3
  • 38
    • 0041657398 scopus 로고    scopus 로고
    • Synthesis of non-natural glycosylamino acids containing tumor-associated carbohydrate antigens
    • S.J. Keding, A. Endo, and S.J. Danishefsky Synthesis of non-natural glycosylamino acids containing tumor-associated carbohydrate antigens Tetrahedron 59 2003 7023 7031
    • (2003) Tetrahedron , vol.59 , pp. 7023-7031
    • Keding, S.J.1    Endo, A.2    Danishefsky, S.J.3
  • 39
    • 1042276934 scopus 로고    scopus 로고
    • Automated solid-phase synthesis of protected tumor-associated antigen and blood group determinant oligosaccharides
    • x nonasaccharide, the Lewis X pentasaccharide and the Lewis Y hexasaccharide was efficiently performed on an automated synthesizer. Only five monomeric building blocks were necessary for the assembly of these target structures and the synthesis of the nonasaccharide was completed within 23 h.
    • (2004) Angew Chem Int Edit , vol.43 , pp. 602-605
    • Love, K.R.1    Seeberger, P.H.2
  • 40
    • 0023944337 scopus 로고
    • Cell-surface anchoring of proteins via glycosyl- phosphatidylinositol structures
    • Ferguson MAJ, and A.F. Williams Cell-surface anchoring of proteins via glycosyl- phosphatidylinositol structures Annu Rev Biochem 57 1988 285 320
    • (1988) Annu Rev Biochem , vol.57 , pp. 285-320
    • Maj, F.1    Williams, A.F.2
  • 41
    • 4544374078 scopus 로고    scopus 로고
    • Chemical synthesis of GPIs and GPI-anchored glycopeptides
    • Z.W. Guo, and L. Bishop Chemical synthesis of GPIs and GPI-anchored glycopeptides Eur J Org Chem 2004 3585 3596 An excellent review summarizing recent approaches for the chemical synthesis of GPI anchors.
    • (2004) Eur J Org Chem , pp. 3585-3596
    • Guo, Z.W.1    Bishop, L.2
  • 42
    • 0036436304 scopus 로고    scopus 로고
    • Synthesis of a polyphosphorylated GPI-anchor core structure
    • M. Lahmann, P.J. Garegg, P. Konradsson, and S. Oscarson Synthesis of a polyphosphorylated GPI-anchor core structure Can J Chem 80 2002 1105 1111
    • (2002) Can J Chem , vol.80 , pp. 1105-1111
    • Lahmann, M.1    Garegg, P.J.2    Konradsson, P.3    Oscarson, S.4
  • 43
    • 0037458994 scopus 로고    scopus 로고
    • A variable concept for the preparation of branched glycosyl phosphatidyl inositol anchors
    • K. Pekari, and R.R. Schmidt A variable concept for the preparation of branched glycosyl phosphatidyl inositol anchors J Org Chem 68 2003 1295 1308
    • (2003) J Org Chem , vol.68 , pp. 1295-1308
    • Pekari, K.1    Schmidt, R.R.2
  • 44
    • 17744411431 scopus 로고    scopus 로고
    • A practical solid-phase synthesis of glycosylphosphatidylinositol precursors
    • N.C. Reichardt, and M. Martin-Lomas A practical solid-phase synthesis of glycosylphosphatidylinositol precursors Angew Chem Int Edit 42 2003 4674 4677
    • (2003) Angew Chem Int Edit , vol.42 , pp. 4674-4677
    • Reichardt, N.C.1    Martin-Lomas, M.2
  • 45
    • 0346434113 scopus 로고    scopus 로고
    • Convergent synthesis of a GPI containing an acylated inositol
    • J. Xue, and Z.W. Guo Convergent synthesis of a GPI containing an acylated inositol J Am Chem Soc 125 2003 16334 16339
    • (2003) J Am Chem Soc , vol.125 , pp. 16334-16339
    • Xue, J.1    Guo, Z.W.2
  • 46
    • 0038627438 scopus 로고    scopus 로고
    • First total synthesis of a GPI-anchored peptide
    • J. Xue, N. Shao, and Z.W. Guo First total synthesis of a GPI-anchored peptide J Org Chem 68 2003 4020 4029
    • (2003) J Org Chem , vol.68 , pp. 4020-4029
    • Xue, J.1    Shao, N.2    Guo, Z.W.3
  • 47
    • 4544373548 scopus 로고    scopus 로고
    • Chemical synthesis of a skeleton structure of sperm CD52 - A GPI-anchored glycopeptide
    • N. Shao, B. Xue, and Z.W. Guo Chemical synthesis of a skeleton structure of sperm CD52 - a GPI-anchored glycopeptide Angew Chem Int Edit 43 2004 1569 1573 The first report of the chemical synthesis of a complex and all natively linked glycopeptide-GPI conjugate. The preparation of a skeleton structure of the sperm CD52 antigen was achieved by first carrying out the separate synthesis of the protected glycopeptides and the GPI. After selective deprotection both segments were coupled by an amide bond to give the entire conjugate.
    • (2004) Angew Chem Int Edit , vol.43 , pp. 1569-1573
    • Shao, N.1    Xue, B.2    Guo, Z.W.3
  • 48
    • 0037102205 scopus 로고    scopus 로고
    • Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria
    • L. Schofield, M.C. Hewitt, K. Evans, M.A. Siomos, and P.H. Seeberger Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria Nature 418 2002 785 789
    • (2002) Nature , vol.418 , pp. 785-789
    • Schofield, L.1    Hewitt, M.C.2    Evans, K.3    Siomos, M.A.4    Seeberger, P.H.5
  • 49
    • 4344585487 scopus 로고    scopus 로고
    • A convergent, versatile route to two synthetic conjugate anti-toxin malaria vaccines
    • P.H. Seeberger, R.L. Soucy, Y.-U. Kwon, D.A. Snyder, and T. Kanemitsu A convergent, versatile route to two synthetic conjugate anti-toxin malaria vaccines Chem Commun 2004 1706 1707
    • (2004) Chem Commun , pp. 1706-1707
    • Seeberger, P.H.1    Soucy, R.L.2    Kwon, Y.-U.3    Snyder, D.A.4    Kanemitsu, T.5
  • 50
    • 0037073195 scopus 로고    scopus 로고
    • Rapid synthesis of a glycosylphosphatidylinositol-based malaria vaccine using automated solid-phase oligosaccharide synthesis
    • M.C. Hewitt, D.A. Snyder, and P.H. Seeberger Rapid synthesis of a glycosylphosphatidylinositol-based malaria vaccine using automated solid-phase oligosaccharide synthesis J Am Chem Soc 124 2002 13434 13436 The automated synthesis of a hexasaccharide, which constitutes a promising malaria vaccine, has been carried out.
    • (2002) J Am Chem Soc , vol.124 , pp. 13434-13436
    • Hewitt, M.C.1    Snyder, D.A.2    Seeberger, P.H.3
  • 51
    • 0346157341 scopus 로고    scopus 로고
    • First synthesis of a malarial prototype: A fully lipidated and phosphorylated GPI membrane anchor
    • J. Lu, K.N. Jayaprakash, and B. Fraser-Reid First synthesis of a malarial prototype: a fully lipidated and phosphorylated GPI membrane anchor Tetrahedron Lett 45 2004 879 882
    • (2004) Tetrahedron Lett , vol.45 , pp. 879-882
    • Lu, J.1    Jayaprakash, K.N.2    Fraser-Reid, B.3
  • 52
    • 2942691414 scopus 로고    scopus 로고
    • Synthesis of a malaria candidate glycosylphosphatidylinositol (GPI) structure: A strategy for fully inositol acylated and phosphorylated GPIs
    • J. Lu, K.N. Jayaprakash, U. Schlueter, and B. Fraser-Reid Synthesis of a malaria candidate glycosylphosphatidylinositol (GPI) structure: a strategy for fully inositol acylated and phosphorylated GPIs J Am Chem Soc 126 2004 7540 7547 The synthesis and properties of a malarial GPI prototype and one variant are reported in this paper.
    • (2004) J Am Chem Soc , vol.126 , pp. 7540-7547
    • Lu, J.1    Jayaprakash, K.N.2    Schlueter, U.3    Fraser-Reid, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.