In pursuit of carbohydrate-based HIV vaccines, part 1: The total synthesis of hybrid-type gp120 fragments

Angewandte Chemie - International Edition

Volumn 43, Issue 19, 2004, Pages 2557-2561

  Mandai, Mihirbaran ^a   Dudkin, Vadim Y ^a   Geng, Xudong ^a   Danishefsky, Samuel J ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Antigens; Carbohydrates; Glycoconjugates; Glycopeptides; Synthetic methods

Indexed keywords

SYNTHESIS (CHEMICAL); VACCINES; VIRUSES;

MANNOSYLATIONS; TRISACCHARIDES;

CARBOHYDRATES;

GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; HYBRID PROTEIN; MANNOSE; TRISACCHARIDE; GLYCOCONJUGATE; GLYCOPEPTIDE; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; OLIGOSACCHARIDE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL MODIFICATION; CHEMICAL REACTION KINETICS; DRUG DESIGN; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; VACCINE PRODUCTION; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; IMMUNOLOGY; SYNTHESIS;

AIDS VACCINES; GLYCOCONJUGATES; GLYCOPEPTIDES; HIV ANTIGENS; HIV ENVELOPE PROTEIN GP120; HUMANS; MOLECULAR STRUCTURE; OLIGOSACCHARIDES; OLIGOSACCHARIDES, BRANCHED-CHAIN;

EID: 2542591183     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200353625     Document Type: Article

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54. In the following paper in this issue, we describe our efforts for the synthesis of high-mannose-type HIV gp120 glycopeptides fragments: X. Geng, V. Y. Dudkin, M. Mandal, S. J. Danishefsky, Angew. Chem. 2004, 116, 2616-2619; Angew. Chem. Int. Ed. 2004, 43, 2562-2565.
55. In the following paper in this issue, we describe our efforts for the synthesis of high-mannose-type HIV gp120 glycopeptides fragments: X. Geng, V. Y. Dudkin, M. Mandal, S. J. Danishefsky, Angew. Chem. 2004, 116, 2616-2619; Angew. Chem. Int. Ed. 2004, 43, 2562-2565.