Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apotosis in human malignant glioma cells

Cancer Research

Volumn 61, Issue 3, 2001, Pages 1162-1170

  Hao, Chunhai ^a   Beguinot, Francesco ^b   Condorelli, Gerolama ^b   Trencia, Alessandra ^b   Van Meir, Erwin G ^c   Yong, V Wee ^d   Parney, Ian F ^a   Roa, Wilson H ^a   Petruk, Kenneth C ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c EMORY UNIVERSITY   (United States)

^d UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; COMPLEMENTARY DNA; DNA FRAGMENT; INHIBITOR OF APOPTOSIS PROTEIN; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN KINASE C; RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; ASTROCYTE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REGULATORY MECHANISM;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ASTROCYTES; CARRIER PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 8; CASPASE 9; CASPASES; CELLS, CULTURED; ENZYME ACTIVATION; GLIOMA; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE GLYCOPROTEINS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PHOSPHOPROTEINS; PROTEIN SYNTHESIS INHIBITORS; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT PROTEINS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR DECOY RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035117038     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Death receptors: Signaling and modulation
2. Identification and characterization of a new member of the TNF family that induces apoptosis
3. The receptor for the cytotoxic ligand TRAIL
4. An antagonist decoy receptor and a death domain-containing receptor for TRAIL
5. TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL
6. Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
7. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
8. TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signaling
9. A novel receptor for Apo2L/TRAIL contains a truncated death domain
10. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
11. Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes
12. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
13. The TNF receptor 1-associated protein TRADD signals cell death and NF-κ B activation
14. FLICE, a novel FADD-homologous ICE Ced3-like protease, is recruited to the CD95 (Fas/APO1) death-inducing signaling complex
15. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO1- and TNF receptor-induced cell death
16. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor
17. An induced proximity model for caspase-8 activation
18. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathways
19. TRAIL receptor-2 signals apoptosis through FADD and caspase-8
20. Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5
21. FADD is required for DR4- and DR5-mediated apoptosis
22. Inhibition of death receptor signals by cellular FLIP
23. Cellular expression, developmental regulation, and phylogenic conservation of PEA15: The major substrate for protein kinase C in astrocytes
24. PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus
25. Knock-out of the neural death effector domain protein PEA-15 demonstrates that its expression protects astrocytes from TNFα-induced apoptosis
26. PED/PEA-15: An antiapoptotic molecule that regulates Fas/TNFRI-induced apoptosis
27. ARFPTEN tumor suppressor genes in human glioma cell lines
28. Differential proliferative response of human and mouse astrocytes to γ-interferon
29. Comparison of in vitro cell cytotoxic assays for tumor necrosis factor
30. Involvement of an ICE-like protease in Fas-mediated apoptosis
31. Tumoricidal activity of tumor necrosis factor-related apoptosis-induced ligand in vivo
32. Safety and antitumor activity of recombinant soluble Apo2 Ligand
33. Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells. Induction and modulation of sensitivity by cytokines
34. Fas ligand expression by astrocytoma in vivo: Maintaining immune privilege in the brain?
35. Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity
36. APO2 ligand: A novel lethal weapon against malignant glioma?
37. Expression of TRAIL and its receptors in human brain tumors
38. Increased death receptor 5 expression by chemotherapeutic agents in human glimas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo
39. Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma
40. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand