-
1
-
-
0030590875
-
Molecular basis for the substrate specificity of protein kinase B; Comparison with MAPKAP kinase-1 and p70 S6 kinase
-
Alessi, D. R., F. B. Caudwell, M. Andjelkovic, B. A. Hemmings, and P. Cohen. 1996. Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett. 399:333-338.
-
(1996)
FEBS Lett.
, vol.399
, pp. 333-338
-
-
Alessi, D.R.1
Caudwell, F.B.2
Andjelkovic, M.3
Hemmings, B.A.4
Cohen, P.5
-
2
-
-
0027460528
-
Characterization of PEA-15, a major substrate for protein kinase C in astrocytes
-
Araujo, H., N. Danzinger, J. Cordier, J. Glowinskl, and H. Chneiweiss. 1993. Characterization of PEA-15, a major substrate for protein kinase C in astrocytes. J. Biol. Chem. 268:5911-5920.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 5911-5920
-
-
Araujo, H.1
Danzinger, N.2
Cordier, J.3
Glowinskl, J.4
Chneiweiss, H.5
-
3
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet, A., A. Bonni, M. J. Zigmond, M. Z. Lin, P. Juo, L. S. Hu, M. J. Anderson, K. C. Arden, J. Blenls, and M. E. Greenberg. 1999. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96:857-868.
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenls, J.9
Greenberg, M.E.10
-
4
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone, M. H., N. Roy, H. R. Stennicke, G. S. Salvesen, T. F. Franke, E. Stanbridge, S. Fricsh, and J. C. Reed. 1998. Regulation of cell death protease caspase-9 by phosphorylation. Science 282:1318-1321.
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
Salvesen, G.S.4
Franke, T.F.5
Stanbridge, E.6
Fricsh, S.7
Reed, J.C.8
-
5
-
-
0037192775
-
Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA-15 anti-apoptotic function
-
Condorelli, G., A. Trencia, G. Vigliotta, A. Perfetti, U. Goglia, E. Autori, A. Cassese, A. Musti, C. Miele, S. Santopietro, P. Formisano, and F. Beguinot. 2002. Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA-15 anti-apoptotic function. J. Biol. Chem. 277:11013-11018.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11013-11018
-
-
Condorelli, G.1
Trencia, A.2
Vigliotta, G.3
Perfetti, A.4
Goglia, U.5
Autori, E.6
Cassese, A.7
Musti, A.8
Miele, C.9
Santopietro, S.10
Formisano, P.11
Beguinot, F.12
-
6
-
-
0032527747
-
PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus
-
Condorelli, G., G. Vigliotta, C. Iavarone, M. Caruso, C. G. Tocchetti, F. Andreozzi, M. F. Tecce, A. Cafieri, P. Formisano, L. Beguinot, and F. Beguinot. 1998. PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus. EMBO J. 17:3858-3865.
-
(1998)
EMBO J.
, vol.17
, pp. 3858-3865
-
-
Condorelli, G.1
Vigliotta, G.2
Iavarone, C.3
Caruso, M.4
Tocchetti, C.G.5
Andreozzi, F.6
Tecce, M.F.7
Cafieri, A.8
Formisano, P.9
Beguinot, L.10
Beguinot, F.11
-
7
-
-
0033527064
-
PED/PEA-15: An anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis
-
Condorelli, G., G. Vigliotta, C. Iavarone, A. Trencia, P. Andalo, F. Oriente, C. Miele, M. Caruso, P. Formisano, and F. Beguinot. 1999. PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis. Oncogene 18:4409-4415.
-
(1999)
Oncogene
, vol.18
, pp. 4409-4415
-
-
Condorelli, G.1
Vigliotta, G.2
Iavarone, C.3
Trencia, A.4
Andalo, P.5
Oriente, F.6
Miele, C.7
Caruso, M.8
Formisano, P.9
Beguinot, F.10
-
8
-
-
0028815390
-
Cellular expression, developmental regulation, and phylogenic conservation of PEA-15, the astrocytic major phosphoprotein and protein kinase C substrate
-
Danzinger, N., M. Yokohama, T. Jay, J. Cordier, J. Glowinski, and H. Chneiweiss. 1995. Cellular expression, developmental regulation, and phylogenic conservation of PEA-15, the astrocytic major phosphoprotein and protein kinase C substrate. J. Neurochem. 64:1016-1025.
-
(1995)
J. Neurochem.
, vol.64
, pp. 1016-1025
-
-
Danzinger, N.1
Yokohama, M.2
Jay, T.3
Cordier, J.4
Glowinski, J.5
Chneiweiss, H.6
-
9
-
-
0036176126
-
Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: Requirement for Akt activation
-
Del Bufalo, D., V. Di Castro, A. Biroccio, M. Varmi, D. Salani, L. Rosano, D. Trisciuoglio, F. Spinella, and A. Bagnato. 2002. Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation. Mol. Pharmacol. 61:524-532.
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 524-532
-
-
Del Bufalo, D.1
Di Castro, V.2
Biroccio, A.3
Varmi, M.4
Salani, D.5
Rosano, L.6
Trisciuoglio, D.7
Spinella, F.8
Bagnato, A.9
-
10
-
-
0032484019
-
CREB is a regulatory target for the protein kinase Akt/PKB
-
Du, K., and M. Montminy. 1998. CREB is a regulatory target for the protein kinase Akt/PKB. J. Biol. Chem. 273:32377-32379.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32377-32379
-
-
Du, K.1
Montminy, M.2
-
11
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase Akt
-
Dudek, H., S. R. Datta, T. F. Franke, M. Brinbaum, R. Yao, G. M. Cooper, R. A. Segal, D. R. Kaplan, and M. E. Greenberg. 1997. Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275:661-665.
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Brinbaum, M.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
12
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Dudek, H., S. R. Datta, X. Tao, S. Masters, H. Fu, Y. Gotoh, and M. E. Greenherg. 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91:231-241.
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Dudek, H.1
Datta, S.R.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenherg, M.E.7
-
13
-
-
0031923788
-
Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line
-
Eves, E. M., W. Xiong, A. Bellacosa, S. G. Kennedy, P. N. Tsichlis, M. R. Rosner, and N. Hay. 1998. Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line. Mol. Cell. Biol. 18:2143-2152.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2143-2152
-
-
Eves, E.M.1
Xiong, W.2
Bellacosa, A.3
Kennedy, S.G.4
Tsichlis, P.N.5
Rosner, M.R.6
Hay, N.7
-
14
-
-
18044405015
-
PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase
-
Formstecher, E., J. W. Ramos, M. Fauquet, D. A. Calderwood, J. C. Hsieh, B. Canton, X. T. Nguyen, J. V. Barnier, J. Camonis, M. H. Ginsberg, and H. Chneiweiss. 2001. PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase. Dev. Cell 1:239-250.
-
(2001)
Dev. Cell
, vol.1
, pp. 239-250
-
-
Formstecher, E.1
Ramos, J.W.2
Fauquet, M.3
Calderwood, D.A.4
Hsieh, J.C.5
Canton, B.6
Nguyen, X.T.7
Barnier, J.V.8
Camonis, J.9
Ginsberg, M.H.10
Chneiweiss, H.11
-
15
-
-
0031039024
-
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
-
Franke, T. F., D. R. Kaplan, L. C. Cantly, and A. Toker. 1997. Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate. Science 275:665-668.
-
(1997)
Science
, vol.275
, pp. 665-668
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantly, L.C.3
Toker, A.4
-
16
-
-
0035117038
-
Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apoptosis in human malignant glioma cells
-
Hao, C., F. Beguinot, G. Condorelli, A. Trencia, H. T. Chen, E. G. Van Meir, V. W. Yong, I. F. Parney, W. H. Roa, and K. C. Petruk. 2001. Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apoptosis in human malignant glioma cells. Cancer Res. 61:1-9.
-
(2001)
Cancer Res.
, vol.61
, pp. 1-9
-
-
Hao, C.1
Beguinot, F.2
Condorelli, G.3
Trencia, A.4
Chen, H.T.5
Van Meir, E.G.6
Yong, V.W.7
Parney, I.F.8
Roa, W.H.9
Petruk, K.C.10
-
17
-
-
0037011120
-
Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain
-
Hill, J. M., H. Vaidyanathan, J. W. Ramos, M. H. Ginsberg, and M. H. Werner. 2002. Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain. EMBO J. 21:6494-6504.
-
(2002)
EMBO J.
, vol.21
, pp. 6494-6504
-
-
Hill, J.M.1
Vaidyanathan, H.2
Ramos, J.W.3
Ginsberg, M.H.4
Werner, M.H.5
-
18
-
-
0024210533
-
Cyclic AMP-responsive DNA-binding protein: Structure based on a cloned placental cDNA
-
Hoeffler, J. P., T. E. Meyer, Y. Yun, J. L. Jameson, and J. F. Habener. 1988. Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA. Science 242:1430-1433.
-
(1988)
Science
, vol.242
, pp. 1430-1433
-
-
Hoeffler, J.P.1
Meyer, T.E.2
Yun, Y.3
Jameson, J.L.4
Habener, J.F.5
-
19
-
-
0031566156
-
14-3-3 zeta protein binds to the carboxyl half of mouse weel kinase
-
Honda, R., Y. Ohba, and H. Yasuda. 1997. 14-3-3 zeta protein binds to the carboxyl half of mouse weel kinase. Biochem. Biophys. Res. Commun. 230:262-265.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.230
, pp. 262-265
-
-
Honda, R.1
Ohba, Y.2
Yasuda, H.3
-
20
-
-
0031570707
-
Assignment of HMAT1, the human homolog of the murine mammary transforming gene (MAT1) associated with tumorigenesis, to Iq21.1, a region frequently gained in human breast cancers
-
Hwang, S., W. Kuo, J. F. Cochron, R. C. Gurman, T. Tsukamoto, G. Bandyopadbyay, K. Mambo, and C. C. Collins. 1997. Assignment of HMAT1, the human homolog of the murine mammary transforming gene (MAT1) associated with tumorigenesis, to Iq21.1, a region frequently gained in human breast cancers. Genomics 42:540-542.
-
(1997)
Genomics
, vol.42
, pp. 540-542
-
-
Hwang, S.1
Kuo, W.2
Cochron, J.F.3
Gurman, R.C.4
Tsukamoto, T.5
Bandyopadbyay, G.6
Mambo, K.7
Collins, C.C.8
-
21
-
-
0030913673
-
Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway
-
Khwaja A., S. Rodriguez-Viciana Wennstrom, P. H. Warne, and J. Downward. 1997. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. EMBO J. 16:2783-2793.
-
(1997)
EMBO J.
, vol.16
, pp. 2783-2793
-
-
Khwaja, A.1
Rodriguez-Viciana Wennstrom, S.2
Warne, P.H.3
Downward, J.4
-
22
-
-
0033216124
-
Knock-out of the neural death effector domain protein PEA-15 demonstrates that its expression protects astrocytes from TNFalpha-induced apoptosis
-
Kitsberg, D., E. Formstecher, M. Fauquet, M. Kubes, J. Cordier, B. Canton, G. Pan, M. Rolli, J. Glowinski, and H. Chneiweiss. 1999. Knock-out of the neural death effector domain protein PEA-15 demonstrates that its expression protects astrocytes from TNFalpha-induced apoptosis. J. Neurosci. 19:8244-8251.
-
(1999)
J. Neurosci.
, vol.19
, pp. 8244-8251
-
-
Kitsberg, D.1
Formstecher, E.2
Fauquet, M.3
Kubes, M.4
Cordier, J.5
Canton, B.6
Pan, G.7
Rolli, M.8
Glowinski, J.9
Chneiweiss, H.10
-
23
-
-
0031819445
-
Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: Identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II in vitro
-
Kubes, M., J. Cordier, J. Glowinski, J. A. Girault, and H. Chneiweiss. 1998. Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II in vitro. J. Neurochem. 71:1303-1314.
-
(1998)
J. Neurochem.
, vol.71
, pp. 1303-1314
-
-
Kubes, M.1
Cordier, J.2
Glowinski, J.3
Girault, J.A.4
Chneiweiss, H.5
-
24
-
-
0037192852
-
AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival
-
Li, Y., D. Dowhenko, and L. A. Lasky. 2002. AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival. J. Biol. Chem. 277:11352-11361.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11352-11361
-
-
Li, Y.1
Dowhenko, D.2
Lasky, L.A.3
-
25
-
-
0030884103
-
PKB/Akt: Connecting phosphoinositide 3-kinase to cell survival and beyond
-
Marte, B. M., and J. Downward. 1997. PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond. Trends Biochem. Sci. 22:355-358.
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 355-358
-
-
Marte, B.M.1
Downward, J.2
-
26
-
-
0036185848
-
The protein kinase B/Akt signalling pathway in human malignancy
-
Nicholson, K. M., and N. G. Anderson. 2002. The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal. 14:381-395.
-
(2002)
Cell Signal.
, vol.14
, pp. 381-395
-
-
Nicholson, K.M.1
Anderson, N.G.2
-
27
-
-
0037077198
-
Identification of 14-3-3zeta as a protein kinase B/Akt substrate
-
Powell, D. W., M. J. Rane, Q. Chen, S. Singh, and K. R. McLeish. 2002. Identification of 14-3-3zeta as a protein kinase B/Akt substrate. J. Biol. Chem. 277:21639-21642.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21639-21642
-
-
Powell, D.W.1
Rane, M.J.2
Chen, Q.3
Singh, S.4
McLeish, K.R.5
-
28
-
-
0035949699
-
AKT plays a central role in tumorigenesis
-
Testa, J. R., and A. Bellacosa. 2001. AKT plays a central role in tumorigenesis. Proc. Natl. Acad. Sci. USA 98:10983-10985.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10983-10985
-
-
Testa, J.R.1
Bellacosa, A.2
-
29
-
-
0036632368
-
The phosphatidylinositol 3-kinase AKT pathway in human cancer
-
Vivano, I., and C. L. Sawyers. 2002. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat. Rev. Cancer 2:489-502.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-502
-
-
Vivano, I.1
Sawyers, C.L.2
-
30
-
-
0345498292
-
Bcl-2 targets the protein kinase Raf-1 to mitochondria
-
Wang, H. G., U. R. Rapp, and J. C. Reed. 1996. Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell 87:629-638.
-
(1996)
Cell
, vol.87
, pp. 629-638
-
-
Wang, H.G.1
Rapp, U.R.2
Reed, J.C.3
-
31
-
-
0037067678
-
Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells
-
Xiao, C., B. F. Yang, N. Asadi, F. Beguinot, and C. Hao. 2002. Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells. J. Biol. Chem. 277:25020-25025.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25020-25025
-
-
Xiao, C.1
Yang, B.F.2
Asadi, N.3
Beguinot, F.4
Hao, C.5
|