Definition of a natural killer NKR-P1A+/CD56-/CD16- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12

Journal of Experimental Medicine

Volumn 184, Issue 5, 1996, Pages 1845-1856

  Bennett, Ian M ^a   Zatsepina, Olga ^a   Zamai, Loris ^a   Azzoni, Livio ^a   Mikheeva, Tatiana ^a   Perussia, Bice ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM IONOPHORE; CD16 ANTIGEN; CD2 ANTIGEN; CD3 ANTIGEN; CD56 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; MESSENGER RNA; PERFORIN; PHORBOL ESTER; SERINE PROTEINASE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CELL DIFFERENTIATION; CYTOTOXICITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE; NATURAL KILLER CELL; NEWBORN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0029847113     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.184.5.1845     Document Type: Article

References (50)

1. Trinchieri, G. 1989. Biology of natural killer cells. Adv. Immunol. 47:187-376.
2. Perussia, B., S. Starr, S. Abraham, V. Fanning, and G. Trinchieri. 1983. Human natural killer cells analyzed by B73.1, a monoclonal antibody blocking Fc receptor functions. I. Characterization of the lymphocyte subset reactive with B73.1. J. Immunol. 83:2133-2141.
3. + T cell subsets and induces early resistance to Leishmania major in mice. J. Exp. Med. 93:567-577.
4. Scharton-Kersten, T., and P. Scott. 1995. The role of the innate immune response in Th1 cell development following Leishmania major infection. J. Leukocyte Biol. 95:515-522.
5. Perussia, B., V. Fanning, and G. Trinchieri. 1983. A human NK and K cell subset shares with cytotoxic T cells expression of the antigen recognized by antibody OKT8. J. Immunol. 83: 223-231.
6. - bone marrow progenitors. J. Immunol. 93:5263-5269.
7. + NK progenitor. Blood. 94:2594-2601.
8. +/DR-primitive progenitors in long-term bone marrow culture. Blood. 92: 2182-2187.
9. + hematopoietic progenitor cells. Blood. 95:3538-3546.
10. Silva, M.R., R. Hoffman, E.F. Srour, and J.L. Ascensao. 1994. Generation of human natural killer cells from immature progenitors does not require marrow stromal cells. Blood. 94:841-846.
11. + hematopoietic progenitor cells. Blood. 87:2632-2640.
12. Cicuttini, F.M., M. Martin, H.T. Petrie, and A.W. Boyd. 1993. A novel population of natural killer progenitor cells isolated from human umbilical cord blood. J. Immunol. 93: 29-37.
13. Hackett, J., Jr., M. Bennett, and V. Kumar. 1985. Origin and differentiation of natural killer cells. I. Characteristics of a transplantable NK cell precursory. Immunol. 134:3731-3738.
14. Moore, T., M. Bennett, and V. Kumar. 1995. Transplantable NK cell progenitors in murine bone marrow. J. Immunol. 95: 1653-1663.
15. + cells. J. Immunol. 86:3124-3131.
16. Perussia, B., C. Ramoni, I. Anegon, M. C. Cuturi, J. Faust, and G. Trinchieri. 1987. Preferential proliferation of natural killer cells among peripheral blood mononuclear cells cocultured with B lymphoblastoid cell lines. Nat. Immun. Cell. Growth. Regul. 87:171-188.
17. Hoffman, R.A., P.C. Kung, W.P. Hansen, and G. Goldstein. 1980. Simple and rapid measurement of human T lymphocytes and their subclasses in peripheral blood. Proc. Natl. Acad. Sci. USA. 80:4914-4917.
18. Fingeroth, J.D., J.J. Weis, T.F. Tedder, J.L. Strominger, P.A. Biro, and D.T. Fearon. 1984. Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2. Proc. Natl. Acad. Sci. USA. 84:4510-4514.
19. Civin, C.I., L.C. Strauss, C. Brovall, M.J. Fackler, J.F. Schwartz, and J.H. Shaper. 1984. Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells. J. Immunol. 84:157-165.
20. + T lymphocytes. I. Inhibition of the IL-2-dependent proliferation by anti-Kp43 monoclonal antibody. J. Immunol. 90:3238-3247.
21. Lamer, L.L., C. Chang, and J.H. Phillips. 1994. Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J. Immunol. 94:2417-2428.
22. Perussia, B., G. Trinchieri, and J.C. Cerrottini. 1976. Functional studies of Fc receptor-bearing human lymphocytes: effect of treatment with proteolytic enzymes. J. Immunol. 123: 681-687.
23. Wysocki, W.L., and V.L. Sato. 1978. Panning for lymphocytes: a method for cell selection. Proc. Natl. Acad. Sci. USA. 75:2844-2848.
24. Toksoz, D., K. Zsebo, K. Smith, S. Hu, D. Brankow, S.V. Suggs, F. Martin, and D.A. Williams. 1992. Support of human hematopoiesis in long-term bone marrow cultures by murine stromal cells selectively expressing the membrane-bound and secreted forms of the human homolog of the steel gene factor, stem cell factor. Proc. Natl. Acad. Sci. USA. 89: 7350-7354.
25. Ravetch, J.V., and B. Perussia. 1989. Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions. J. Exp. Med. 89: 481-497.
26. Uphoff, C.C., Z.B. Hu, S.M. Gignac, W. Ma, F.A. Rainey, M. Kreutz, W.D. Ludwig, and H.G. Drexler. 1994. Characterization of the monocyte-specific esterase (MSE) gene. Leukemia. 94:1510-1526.
27. Tabor, S. 1996. Phosphatases and Kinases. In Current Protocols in Molecular Biology. F.M. Ausubel, R. Brent, R.E. Kingston, D.D. Moore, J.G. Seidman, J.A. Smith, and K. Struhl, editors. John Wiley and Sons, Inc., New York. 3.10.1-3.10.5.
28. Cuturi, M.C., M. Murphy, M.P. Costa-Giomi, R. Weinmann, B. Perussia, and G. Trinchieri. 1987. Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes. J. Exp. Med. 87:1581-1594.
29. Murphy, M., R. Loudon, M. Kobayashi, and G. Trinchieri. 1986. Gamma interferon and lymphotoxin, released by activated T cells, synergize to inhibit granulocyte/monocyte colony formation. J. Exp. Med. 86:263-279.
30. + T lymphocytes. J. Immunol. 90:574-582.
31. Cassatella, M.A., L. Meda, S. Gasperini, A. D'Andrea, X. Ma, and G. Trinchieri. 1995. Interleukin-12 production by human polymorphonuclear leukocytes. Eur. J. Immunol. 25:1-5.
32. Koizumi, H., C.C. Liu, L.M. Zheng, S.V. Joag, N.K. Bayne, J. Holoshitz, and J.D. Young. 1991. Expression of perforin and serine esterases by human gamma/delta T cells. J. Exp. Med. 91:499-502.
33. Wagner, L., W. Base, M. Weisholzer, V. Sexl, H. Bognar, and C. Worman. 1991. Detection of BLT-substrate-specific proteases in individual human peripheral blood leukocytes and bone marrow cells. J. Immunol. Methods. 142:147-155.
34. Nagler, A., L.L. Lanier, S. Cwirla, and J.H. Phillips. 1989. Comparative studies of human FcRIII-positive and negative natural killer cells. J. Immunol. 89:3183-3191.
35. Trinchieri, G., M. Matsumoto-Kobayashi, S.C. Clark, J. Sheera, L. London, and B. Perussia. 1984. Response of resting human peripheral blood natural killer cells to interleukin 2. J. Exp. Med. 160:1147-1169.
36. Matos, M.E., G.S. Schnier, M.S. Beecher, L.K. Ashman, D.E. William, and M.A. Caligiuri. 1993. Expression of a functional c-kit receptor on a subset of natural killer cells. J. Exp. Med. 93:1079-1084.
37. Fleit, H.B., S.D. Wright, C.J. Dune, J.E. Valinsky, and J.C. Unkeless. 1984. Ontogeny of Fc receptors and complement receptor (CR3) during human myeloid differentiation. J. Clin. Invest. 84:516-525.
38. Phillips, J.H., C.W. Chang, and L.L. Lanier. 1991. Platelet-induced expression of Fc gamma RIII (CD16) on human monocytes. Eur. J. Immunol. 91:895-899.
39. Miller, J.S., S. Delkers, C. Verfaillie, and P. McGlave. 1992. Role of monocytes in the expansion of human activated natural killer cells. Blood. 80:2221-2229.
40. Giorda, R., W.U. Rudert, C. Vavassori, W.H. Chambers, J.C. Hiserodt, and M. Trucco. 1990. NKR-P1, a signal transduction molecule on natural killer cells. Science (Wash. DC). 4974:1298-1300.
41. Bezouska, K., C.T. Yuen, J. O'Brien, R.A. Childs, W. Chai, A.M. Lawson, K. Drbal, A. Fiserova, M. Pospisil, and T. Feizi. 1994. Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity. Nature (Lond.). 94:150-157.
42. Bezouska, K., G. Vlahas, O. Horvath, G. Jinochova, A. Fiserova, R. Giorda, W.H. Chambers, T. Feizi, and M. Pospisil. 1994. Rat natural killer cell antigen, NKR-P1, related to C-type animal lectins is a carbohydrate-binding protein. J. Biol. Chem. 94:16945-16952.
43. Robertson, M.J., M.A. Caligiuri, T.J. Manley, H. Levine, and J. Ritz. 1990. Human natural killer cell adhesion molecules: differential expression after activation and participation in cytolysis. J. Immunol. 145:3194-3201.
44. Schmits, R., T.M. Kundig, D.M. Baker, G. Shumaker, J.J.L. Simard, G. Duncan, A. Wakeham, A. Shahinian, A. van der Heiden, M.F. Bachmann, P.S. Ohashi et al. 1996. LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor. J. Exp. Med. 183:1415-1426.
45. Ryan, J.C., J. Turck, E.C. Niemi, W.M. Yokoyama, and W.E. Seaman. 1992. Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules. J. Immunol. 92:1631-1635.
46. Magram, J., S.E. Connaughton, R.R. Warner, D.M. Carvajal, C. Wu, J. Ferrante, C. Stewart, U. Sarmiento, D.A. Faherty, and M.K. Gately. 1996. IL-12-deficient mice are defective in IFN-gamma production and type 1 cytokine responses. Immunity. 4:471-481.
47. Hirayama, F., N. Katayama, S. Neben, D. Donaldson, E.B. Nickbarg, S.C. Clark, and M. Ogawa. 1994. Synergistic interaction between interleukin-12 and steel factor in support of proliferation of murine lymphohematopoietic progenitors in culture. Blood. 94:92-98.
48. Jacobsen, S.E., O.P. Veiby, and E.B. Smeland. 1993. Cytotoxic lymphocyte maturation factor (interleukin 12) is a synergistic growth factor for hematopoietic stem cells. J. Exp. Med. 93:413-418.
49. Bennett, I.M., and B. Perussia. 1996. Effects of IL-12 on human natural killer cell differentiation. Proc. NY Acad. Sci. In press.
50. Perussia, B. 1991. Lymphokine-activated killer cells, natural killer cells and cytokines. Curr. Opin. Immunol. 91:49-55.