메뉴 건너뛰기




Volumn 162, Issue 5, 1999, Pages 2785-2790

Role of a STAT binding site in the regulation of the human perforin promoter

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 2; INTERLEUKIN 6; LUCIFERASE; PERFORIN; STAT1 PROTEIN; STAT5 PROTEIN; STAT5B PROTEIN;

EID: 0033105650     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (65)

References (31)
  • 2
    • 0023693490 scopus 로고
    • Homology of perforin to the ninth component of complement (C9)
    • Shinkai, Y., K. Takio, and K. Okumura. 1988. Homology of perforin to the ninth component of complement (C9). Nature 334:525.
    • (1988) Nature , vol.334 , pp. 525
    • Shinkai, Y.1    Takio, K.2    Okumura, K.3
  • 3
    • 0022497854 scopus 로고
    • Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity
    • Young, J. D., H. Hengartner, E. R. Podack, and Z. A. Cohn. 1986. Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity. Cell 44:849.
    • (1986) Cell , vol.44 , pp. 849
    • Young, J.D.1    Hengartner, H.2    Podack, E.R.3    Cohn, Z.A.4
  • 4
    • 0022253052 scopus 로고
    • Isolation of a lytic, pore-forming protein (perforin) from cytolytic T-lymphocytes
    • Masson, D., and J. Tschopp. 1985. Isolation of a lytic, pore-forming protein (perforin) from cytolytic T-lymphocytes. J. Biol. Chem. 260:9069.
    • (1985) J. Biol. Chem. , vol.260 , pp. 9069
    • Masson, D.1    Tschopp, J.2
  • 7
    • 0025191074 scopus 로고
    • Genomic organization of the mouse pore-forming protein (perforin) gene and localization to chromosome 10: Similarities to and differences from C9
    • Trapani, J. A., B. S. Kwon, C. A. Kozak, C. Chintamaneni, J. D. Young, and B. Dupont. 1990. Genomic organization of the mouse pore-forming protein (perforin) gene and localization to chromosome 10: similarities to and differences from C9. J. Exp. Med. 171:545.
    • (1990) J. Exp. Med. , vol.171 , pp. 545
    • Trapani, J.A.1    Kwon, B.S.2    Kozak, C.A.3    Chintamaneni, C.4    Young, J.D.5    Dupont, B.6
  • 8
    • 0025778274 scopus 로고
    • Structure of the mouse pore-forming protein (perforin) gene: Analysis of transcription initiation site, 5′ flanking sequence, and alternative splicing of 5′ untranslated regions
    • Youn, B. S., C. C. Liu, K. K. Kim, J. D. Young, M. H. Kwon, and B. S. Kwon. 1991. Structure of the mouse pore-forming protein (perforin) gene: analysis of transcription initiation site, 5′ flanking sequence, and alternative splicing of 5′ untranslated regions. J. Exp. Med. 173:813.
    • (1991) J. Exp. Med. , vol.173 , pp. 813
    • Youn, B.S.1    Liu, C.C.2    Kim, K.K.3    Young, J.D.4    Kwon, M.H.5    Kwon, B.S.6
  • 9
    • 0024822421 scopus 로고
    • Structure of the human perforin gene: A simple gene organization with interesting potential regulatory sequences
    • Lichtenheld, M. G., and E. R. Podack. 1989. Structure of the human perforin gene: a simple gene organization with interesting potential regulatory sequences. J. Immunol. 143:4267.
    • (1989) J. Immunol. , vol.143 , pp. 4267
    • Lichtenheld, M.G.1    Podack, E.R.2
  • 10
    • 0025674005 scopus 로고
    • Novel putative promoter/enhancer sequences are shared by the mouse and human perforin (Pfp) genes
    • Trapani, J. A., and B. Dupont. 1990. Novel putative promoter/enhancer sequences are shared by the mouse and human perforin (Pfp) genes. Tissue Antigens 36:228.
    • (1990) Tissue Antigens , vol.36 , pp. 228
    • Trapani, J.A.1    Dupont, B.2
  • 11
    • 0026687790 scopus 로고
    • Structure and function of the murine perforin promoter and upstream region: Reciprocal gene activation or silencing in perforin positive and negative cells
    • Lichtenheld, M. G., and E. R. Podack. 1992. Structure and function of the murine perforin promoter and upstream region: reciprocal gene activation or silencing in perforin positive and negative cells. J. Immunol. 149:2619.
    • (1992) J. Immunol. , vol.149 , pp. 2619
    • Lichtenheld, M.G.1    Podack, E.R.2
  • 12
    • 0027495664 scopus 로고
    • Identification of a killer cell-specific regulatory element of the mouse perforin gene: An Ets-binding site-homologous motif that interacts with Ets-related proteins
    • Koizumi, H., M. F. Horta, B. S. Youn, K. C. Fu, B. S. Kwon, J. D. Young, and C. C. Liu. 1993. Identification of a killer cell-specific regulatory element of the mouse perforin gene: an Ets-binding site-homologous motif that interacts with Ets-related proteins. Mol. Cell. Biol. 13:6690.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6690
    • Koizumi, H.1    Horta, M.F.2    Youn, B.S.3    Fu, K.C.4    Kwon, B.S.5    Young, J.D.6    Liu, C.C.7
  • 13
    • 0030587880 scopus 로고    scopus 로고
    • A critical role of Sp1- and Ets-related transcription factors in maintaining CTL-specific expression of the mouse perforin gene
    • Youn, B. S., K. K. Kim, and B. S. Kwon. 1996. A critical role of Sp1- and Ets-related transcription factors in maintaining CTL-specific expression of the mouse perforin gene. J. Immunol. 157:3499.
    • (1996) J. Immunol. , vol.157 , pp. 3499
    • Youn, B.S.1    Kim, K.K.2    Kwon, B.S.3
  • 14
    • 0031568648 scopus 로고    scopus 로고
    • Non-killer cell-specific transcription factors silence the perforin promoter
    • Zhang, Y., and M. G. Lichtenheld. 1997. Non-killer cell-specific transcription factors silence the perforin promoter. J. Immunol. 158:1734.
    • (1997) J. Immunol. , vol.158 , pp. 1734
    • Zhang, Y.1    Lichtenheld, M.G.2
  • 15
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell, J. E. J. 1997. STATs and gene regulation. Science 277:1630.
    • (1997) Science , vol.277 , pp. 1630
    • Darnell, J.E.J.1
  • 16
    • 0030046753 scopus 로고    scopus 로고
    • STATs: Signal transducers and activators of transcription
    • Ihle, J. N. 1996. STATs: signal transducers and activators of transcription. Cell 84:331.
    • (1996) Cell , vol.84 , pp. 331
    • Ihle, J.N.1
  • 17
    • 0029962515 scopus 로고    scopus 로고
    • Differential regulation of interleukin-12- and interleukin-15-induced natural killer cell activation by interleukin-4
    • Salvucci, O., F. Mami-Chouaib, J. L. Moreau, J. Theze, J. Chehimi, and S. Chouaib. 1996. Differential regulation of interleukin-12- and interleukin-15-induced natural killer cell activation by interleukin-4. Eur. J. Immunol. 26:2736.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 2736
    • Salvucci, O.1    Mami-Chouaib, F.2    Moreau, J.L.3    Theze, J.4    Chehimi, J.5    Chouaib, S.6
  • 18
    • 0025142394 scopus 로고
    • IL-2 and IL-6 synergize to augment the pore-forming protein gene expression and cytotoxic potential of human peripheral blood T cells
    • Smyth, M. J., J. R. Ortaldo, W. Bere, H. Yagita, K. Okumura, and H. A. Young. 1990. IL-2 and IL-6 synergize to augment the pore-forming protein gene expression and cytotoxic potential of human peripheral blood T cells. J. Immunol. 145:1159.
    • (1990) J. Immunol. , vol.145 , pp. 1159
    • Smyth, M.J.1    Ortaldo, J.R.2    Bere, W.3    Yagita, H.4    Okumura, K.5    Young, H.A.6
  • 19
    • 0026048392 scopus 로고
    • IL-7 regulation of cytotoxic lymphocytes: Pore-forming protein gene expression, interferon-γ production, and cytotoxicity of human peripheral blood lymphocytes subsets
    • Smyth, M. J., Y. Norihisa, J. R. Gerard, H. A. Young, and J. R. Ortaldo. 1991. IL-7 regulation of cytotoxic lymphocytes: pore-forming protein gene expression, interferon-γ production, and cytotoxicity of human peripheral blood lymphocytes subsets. Cell. Immunol. 138:390.
    • (1991) Cell. Immunol. , vol.138 , pp. 390
    • Smyth, M.J.1    Norihisa, Y.2    Gerard, J.R.3    Young, H.A.4    Ortaldo, J.R.5
  • 20
    • 0029096189 scopus 로고
    • IL-12 synergizes with IL-2 to induce lymphokine-activated cytotoxicity and perforin and granzyme gene expression in fresh human NK cells
    • DeBlaker-Hohe, D. F., A. Yamauchi, C. R. Yu, J. A. Horvath-Arcidiacono, and E. T. Bloom. 1995. IL-12 synergizes with IL-2 to induce lymphokine-activated cytotoxicity and perforin and granzyme gene expression in fresh human NK cells. Cell. Immunol. 165:33.
    • (1995) Cell. Immunol. , vol.165 , pp. 33
    • DeBlaker-Hohe, D.F.1    Yamauchi, A.2    Yu, C.R.3    Horvath-Arcidiacono, J.A.4    Bloom, E.T.5
  • 22
    • 0029937270 scopus 로고    scopus 로고
    • Impaired IL-12 responses and enhanced development of Th2 cells in stat4-deficient mice
    • Kaplan, M. H., Y. L. Sun, T. Hoey, and M. J. Grusby. 1996. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. Nature 382:174.
    • (1996) Nature , vol.382 , pp. 174
    • Kaplan, M.H.1    Sun, Y.L.2    Hoey, T.3    Grusby, M.J.4
  • 23
    • 0019523223 scopus 로고
    • Characteristics of human large granular lymphocytes and relationship to natural killer and K cells
    • Timonen, T., J. R. Ortaldo, and R. B. Herberman. 1981. Characteristics of human large granular lymphocytes and relationship to natural killer and K cells. J. Exp. Med. 153:569.
    • (1981) J. Exp. Med. , vol.153 , pp. 569
    • Timonen, T.1    Ortaldo, J.R.2    Herberman, R.B.3
  • 24
    • 0020561224 scopus 로고
    • Immunoglobulin gene transcription is activated by downstream sequence elements
    • Queen, C., and D. Baltimore. 1983. Immunoglobulin gene transcription is activated by downstream sequence elements. Cell 33:741.
    • (1983) Cell , vol.33 , pp. 741
    • Queen, C.1    Baltimore, D.2
  • 25
    • 0030010569 scopus 로고    scopus 로고
    • Differential utilization of janus kinase-signal transducer activator of transcription signaling pathways in the stimulation of human natural killer cells by IL-2, IL-12, and IFN-α
    • Yu, C. R., J. X. Lin, D. W. Fink, S. Akira, E. T. Bloom, and A. Yamauchi. 1996. Differential utilization of Janus kinase-signal transducer activator of transcription signaling pathways in the stimulation of human natural killer cells by IL-2, IL-12, and IFN-α. J. Immunol. 157:126.
    • (1996) J. Immunol. , vol.157 , pp. 126
    • Yu, C.R.1    Lin, J.X.2    Fink, D.W.3    Akira, S.4    Bloom, E.T.5    Yamauchi, A.6
  • 26
    • 0027433497 scopus 로고
    • Functional effects of CD30 on a large granular lymphoma cell line, YT: Inhibition of cytotoxicity, regulation of CD28 and IL-2R, and induction of homotypic aggregation
    • Bowen, M. A., K. J. Olsen, L. Cheng, D. Avila, and E. R. Podack. 1993. Functional effects of CD30 on a large granular lymphoma cell line, YT: inhibition of cytotoxicity, regulation of CD28 and IL-2R, and induction of homotypic aggregation. J. Immunol. 151:5896.
    • (1993) J. Immunol. , vol.151 , pp. 5896
    • Bowen, M.A.1    Olsen, K.J.2    Cheng, L.3    Avila, D.4    Podack, E.R.5
  • 27
    • 0029004009 scopus 로고
    • PuF/NM23-H2/NDPK-B transactivates a human c-myc promoter-CAT gene via a functional nuclease hypersensitive element
    • Berberich, S. J., and E. H. Postel. 1995. PuF/NM23-H2/NDPK-B transactivates a human c-myc promoter-CAT gene via a functional nuclease hypersensitive element. Oncogene 10:2343.
    • (1995) Oncogene , vol.10 , pp. 2343
    • Berberich, S.J.1    Postel, E.H.2
  • 28
    • 0031467318 scopus 로고    scopus 로고
    • Interaction of STAT5 dimers on two low affinity binding sites mediates interleukin 2 (IL-2) stimulation of IL-2 receptor a gene transcription
    • Meyer, W. K., P. Reichenbach, U. Schindler, E. Soldaini, and M. Nabholz. 1997. Interaction of STAT5 dimers on two low affinity binding sites mediates interleukin 2 (IL-2) stimulation of IL-2 receptor a gene transcription. J. Biol. Chem. 272:31821.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31821
    • Meyer, W.K.1    Reichenbach, P.2    Schindler, U.3    Soldaini, E.4    Nabholz, M.5
  • 29
    • 0031277415 scopus 로고    scopus 로고
    • IL-2 and IL-7 induce heterodimerization of STAT5 isoforms in human peripheral blood T lymphoblasts
    • Rosenthal, L. A., K. D. Winestock, and D. S. Finbloom. 1997. IL-2 and IL-7 induce heterodimerization of STAT5 isoforms in human peripheral blood T lymphoblasts. Cell. Immunol. 181:172.
    • (1997) Cell. Immunol. , vol.181 , pp. 172
    • Rosenthal, L.A.1    Winestock, K.D.2    Finbloom, D.S.3
  • 30
    • 0028964916 scopus 로고
    • Identification and purification of human STAT proteins activated in response to interleukin-2
    • Hou, J., U. Schindler, W. J. Henzel, S. C. Wong, and S. L. McKnight. 1995. Identification and purification of human STAT proteins activated in response to interleukin-2. Immunity 2:321.
    • (1995) Immunity , vol.2 , pp. 321
    • Hou, J.1    Schindler, U.2    Henzel, W.J.3    Wong, S.C.4    McKnight, S.L.5
  • 31
    • 0031879572 scopus 로고    scopus 로고
    • Characterization of cytokine differential induction of STAT complexes in primary human T and NK cells
    • Yu, C. R., H. A. Young, and J. R. Ortaldo. 1998. Characterization of cytokine differential induction of STAT complexes in primary human T and NK cells. J. Leukocyte Biol. 64:245.
    • (1998) J. Leukocyte Biol. , vol.64 , pp. 245
    • Yu, C.R.1    Young, H.A.2    Ortaldo, J.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.