Histone H2AX is phosphorylated at sites of retroviral DNA integration but is dispensable for postintegration repair

Journal of Biological Chemistry

Volumn 279, Issue 44, 2004, Pages 45810-45814

  Daniel, René ^a,c   Ramcharan, Joseph ^a   Rogakou, Emmy ^b,d   Taganov, Konstantin D ^a,e   Greger, James G ^a   Bonner, William ^b   Nussenzweig, André ^b   Katz, Richard A ^a   Skalka, Anna Marie ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING   (Greece)

^e CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; FUNCTIONS; GENETIC ENGINEERING; INTEGRATION; REACTION KINETICS;

GENOTOXIC AGENTS; IMMUNOPRECIPITATION METHODS; PHOSPHORYLATION; STABLE TRANSDUCTION;

DNA;

DOUBLE STRANDED DNA; GAMMA HISTONE H2AX; HISTONE H2A; HISTONE H2AX; UNCLASSIFIED DRUG; VIRUS DNA;

ANIMAL CELL; ARTICLE; CHROMATIN; DNA DAMAGE; DNA INTEGRATION; DNA RECOMBINATION; DNA REPAIR; DNA STRAND BREAKAGE; GENOTOXICITY; IMMUNOPRECIPITATION; IONIZING RADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RETROVIRUS; SIGNAL TRANSDUCTION; VIRUS DNA CELL DNA INTERACTION;

HELA CELLS; HISTONES; HUMANS; PHOSPHORYLATION; RECOMBINATION, GENETIC; RETROVIRIDAE; VIRUS INTEGRATION;

ANIMALIA; RNA VIRUSES; UNIDENTIFIED RETROVIRUS;

EID: 8544226285     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M407886200     Document Type: Article

References (35)

1. Rogakou, E. P., Pilch, D. R., Orr, A. H., Ivanova, V. S., and Bonner, W. M. (1998) J. Biol. Chem. 273, 5858-5868
2. Burma, S., Chen, B. P., Murphy, M. B., Kurimasa, A., and Chen, D. J. (2001) J. Biol. Chem. 276, 42462-42467
3. Ward, I. M., and Chen, J. (2001) J. Biol. Chem. 276, 47759-47762
4. Stiff, T., O'Driscoll, M., Rief, N., Iwabuchi, K., Lobrich, M., and Jeggo, P. A. (2004) Cancer Res. 64, 2390-2396
5. Rogakou, E. P., Boon, C., Redon, C., and Bonner, W. M. (1999) J. Cell Biol. 146, 905-916
6. Redon, C., Pilch, D., Rogakou, E., Sedelnikova, O., Newrock, K., and Bonner, W. (2002) Curr. Opin. Genet. Dev. 12, 162-169
7. Celeste, A., Petersen, S., Romanienko, P. J., Fernandez-Capetillo, O., Chen, H. T., Sedelnikova, A. O., Reina-San-Martin, B., Coppola, V., Meffre, E., Difilippantonio, M. J., Redon, C., Pilch, D. R., Olaru, A., Eckhaus, M., Camerini-Otero, D. C., Tessarollo, L., Livak, F., Manova, K., Bonner, W. M., Nussenzweig, M. C., and Nussenzweig, A. (2002) Science 296, 922-927
8. Bassing, C. H., Chua, K. F., Sekiguchi, J., Suh, H., Whitlow, S. R., Fleming, J. C., Monroe, B. C., Ciccone, D. N., Yan, C., Vlasakova, K., Livingston, D. M., Ferguson, D. O., Scully, R., and Alt, F. W. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 8173-8178
9. Chen, H. T., Bhandoola, A., Difilippantonia, M. J., Zhu, J., Brown, M. J., Tai, X., Rogakou, E. P., Brotz, T. M., Bonner, W. M., Ried, T., and Nussenzweig, A. (2000) Science 290, 1962-1965
10. Petersen, S., Casellas, R., Reina-San-Martin, B., Chen, H. T., Difilippantonio, M. J., Wilson, P. C., Hanitsch, L., Celeste, A., Muramatsu, M., Pilch, D. R., Redon, C., Ried, T., Bonner, W. M., Honjo, T., Nussenzweig, M. C., and Nussenzweig, A. (2001) Nature 414, 660-665
11. Mahadevaiah, S. K., Turner, J. M., Baudat, F., Rogakou, E. P., de Boer, P., Blanco-Rodriguez, J., Jasin, M., Keeney, S., Bonner, W. M., and Burgoyne, P. S. (2001) Nat. Genet. 27, 271-276
12. Fernandez-Capetillo, O., Mahadevaiah, S. K., Celeste, A., Romanienko, P. J., Camerini-Otero, R. D., Bonner, W. M., Manova, K., Burgoyne, P., and Nussenzweig, A. (2003) Dev. Cell 4, 497-508
13. Vandegraaff, N., Kumar, R., and Burrell, C. J. (2001) J. Virol. 75, 11253-11260
14. Katz, R. A., and Skalka, A. M. (1994) Annu. Rev. Biochem. 63, 133-173
15. Craig, N. L. (1996) Science 271, 1512
16. van Gent, D. C., Mizuuchi, K., and Geliert, M. (1996) Science 271, 1592-1594
17. Daniel, R., Katz, R. A., and Skalka, A. M. (1999) Science 284, 644-647
18. Daniel, R., Katz, R. A., Merkel, G., Kittle, J. C., Yen, T. J., and Skalka, A. M. (2001) Mol. Cell. Biol. 21, 1164-1172
19. Daniel, R., Kao, G., Taganov, K., Greger, J., Favorova, O., Merkel, G., Yen, T. J., Katz, R. A., and Skalka, A. M. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 4778-4783
20. Daniel, R., Greger, J., Katz, R. A., Taganov, K., Wu, X., Kappes, J. C., and Skalka, A. M. (2004) J. Virol. 78, 8573-8581
21. Boyd, K. E., and Farnham, P. J. (1999) Mol. Cell. Biol. 19, 8393-8399
22. Katz, R. A., Greger, J. G., Boimel, P., and Skalka, A. M. (2003) J. Virol. 77, 13412-13417
23. Katz, R. A., Greger, J. G., Darby, K., Boimel, P., Rall, G. F., and Skalka, A. M. (2002) J. Virol. 76, 5422-5434
24. Celeste, A., Fernandez-Capetillo, O., Kruhlak, M. J., Pilch, D. R., Staudt, D. W., Lee, A., Bonner, R. F., Bonner, W. M., and Nussenzweig, A. (2003) Nat. Cell Biol. 5, 675-679
25. Celeste, A., Difilippantonio, S., Difilippantonio, M. J., Fernandez-Capetillo, O., Pilch, D. R., Sedelnikova, O. A., Eckhaus, M., Ried, T., Bonner, W. M., and Nussenzweig, A. (2003) Cell 114, 371-383
26. Paull, T. T., Rogakou, E. P., Yamazaki, V., Kirchgessner, C. U., Gellert, M., and Bonner, W. M. (2000) Curr. Biol. 10, 886-895
27. Stewart, G. S., Wang, B., Bignell, C. R., Taylor, A. M., and Elledge, S. J. (2003) Nature 421, 961-966
28. Ward, I. M., Minn, K., Jorda, K. G., and Chen, J. (2003) J. Biol. Chem. 278, 19579-19582
29. Kobayashi, J., Tauci, H., Sakamoto, S., Nakamura, A., Morishima, K., Matsuura, S., Kobayashi, T., Tamai, K., Tanimoto, K., and Komatsu, K. (2002) Curr. Biol. 12, 1846-1851
30. Fernandez-Capetillo, O., Chen, H. T., Celeste, A., Ward, I. M., Romanienko, P. J., Morales, J. C., Naka, K., Xia, Z., Camerini-Otero, R. D., Motoyama, N., Carpenter, P. B., Bonner, W. M., Chen, J., and Nussenweig, A. (2002) Nat. Cell Biol. 4, 993-997
31. Reina-San-Martin, B., Difilippantonio, S., Hanitsch, L., Masilamani, R. F., Nussenzweig, A., and Nussenzweig, M. C. (2003) J. Exp. Med. 197, 1767-1778
32. Bassing, C. H., Suh, H., Ferguson, D. O., Chua, K. F., Manis, J., Eckersdorff, M., Gleason, M., Bronson, R., Lee, C., and Alt, F. W. (2003) Cell 114, 359-370
33. Bassing, C. H., and Alt, F. W. (2004) Cell Cycle 3, 149-153
34. Fernandez-Capetillo, O., Lee, A., Nussenzweig, M. C., and Nussenzweig, A. (2004) DNA Repair (Amst.) 3, 959-967
35. Jones, J. M., and Gellert, M. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 15446-15451