Kinetics of human immunodeficiency virus type 1 (HIV) DNA integration in acutely infected cells as determined using a novel assay for detection of integrated HIV DNA

Journal of Virology

Volumn 75, Issue 22, 2001, Pages 11253-11260

  Vandegraaff, N ^a   Kumar, R ^a   Burrell, C J ^a   Li, P ^a  

^a INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRASE; PRIMER DNA; VIRUS DNA;

ARTICLE; CHROMOSOME; CONTROLLED STUDY; DNA DETERMINATION; DNA INTEGRATION; DNA SYNTHESIS; EXPERIMENTAL MODEL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS DNA CELL DNA INTERACTION; VIRUS REPLICATION;

CELL LINE; DNA, VIRAL; HIV-1; HUMANS; KINETICS; POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; VIRUS INTEGRATION; VIRUS REPLICATION;

EID: 0034760352     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.22.11253-11260.2001     Document Type: Article

References (34)

1. Kinetic analysis of HIV-1 early replicative steps in a coculture system
2. Active nuclear import of human immunodeficiency virus type 1 preintegration complexes
3. Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection
4. A quantitative assay for HIV DNA integration in vivo
5. The barrier-to-autointegration protein is a host factor for HIV type 1 integration
6. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
7. Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection
8. Latent reservoirs of HIV: Obstacles to the eradication of virus
9. In vivo fate of HIV-1-infected T cells: Quantitative analysis of the transition to stable latency
10. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
11. Monokine regulation of human immunodeficiency virus-I expression in a chronically infected human T cell clone
12. Integration is required for productive infection of monocyte-derived macrophages by human immunodeficiency virus type 1
13. HiV-1 cDNA integration: Requirement of HMG I(Y) protein for function of preintegration complexes in vitro
14. Biological and biochemical characterization of a cloned Leu-3- cell surviving infection with the acquired immune deficiency syndrome retrovirus
15. Mitogen requirements for the in vitro propagation of cutaneous T-cell lymphomas
16. Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells
17. Selective extraction of polyoma DNA from infected mouse cell cultures
18. A fundamental division in the Alu family of repeated sequences
19. Characterization of HIV replication complexes early after cell-to-cell infection
20. Stepwise analysis of reverse transcription in a cell-to-cell human immunodeficiency virus infection model: Kinetics and implications
21. Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: Evidence for differential gene expression
22. Requirement of active human immunodeficiency virus type 1 integrase enzyme for productive infection of human T-lymphoid cells
23. Human immunodeficiency virus type 1 DNA synthesis, integration, and efficient viral replication in growth-arrested T cells
24. Retroviral cDNA integration: Stimulation by HMG I family proteins
25. Synthesis of human immunodeficiency virus DNA in a cell-to-cell transmission model
26. Human immunodeficiency virus type 1 preintegration complexes: Studies of organization and composition
27. Persistent human immunodeficiencv virus type 1 infection of monoblastoid cells leads to accumulation of self-integrated viral DNA and to production of defective virions
28. Integration is essential for efficient gene expression of human immunodeficiency virus type 1
29. Human immunodeficiency virus type 1 replication is blocked prior to reverse transcription and integration in freshly isolated peripheral blood monocytes
30. HIV-1 replication is controlled at the level of T cell activation and proviral integration
31. Specific inhibition of human immunodeficiencv virus type 1 (HIV-1) integration in cell culture: Putative inhibitors of HIV-1 integrase
32. Clonal expansion of human T-cell leukemia virus type 1-infected cells in asymptomatic and symptomatic carriers without malignancy
33. Productive human immunodeficiency virus type 1 (HIV-1) infection of non-proliferating human monocytes
34. Quantitative assessment of integrated and episomal HIV DNA