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Volumn , Issue APRIL, 2012, Pages

GSK-3β and memory formation

Author keywords

Aging; Alzheimer's disease; Memory formation; Memory impairment; Tau

Indexed keywords

AMYLOID BETA PROTEIN; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TAU PROTEIN;

EID: 85197334850     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2012.00047     Document Type: Review
Times cited : (20)

References (61)
  • 2
    • 5144233312 scopus 로고    scopus 로고
    • Context memories and reactivation: Constraints on the reconsolidation hypothesis
    • Biedenkapp, J. C., and Rudy, J. W. (2004). Context memories and reactivation: constraints on the reconsolidation hypothesis. Behav. Neurosci. 118, 956-964.
    • (2004) Behav. Neurosci. , vol.118 , pp. 956-964
    • Biedenkapp, J.C.1    Rudy, J.W.2
  • 3
    • 0025106123 scopus 로고
    • Neurofibrillary changes confined to the entorhinal region and an abundance of cortical amyloid in cases of prese-nile and senile dementia
    • Braak, H., and Braak, E. (1990). Neurofibrillary changes confined to the entorhinal region and an abundance of cortical amyloid in cases of prese-nile and senile dementia. Acta Neu-ropathol. 80, 479-486.
    • (1990) Acta Neu-ropathol. , vol.80 , pp. 479-486
    • Braak, H.1    Braak, E.2
  • 4
    • 0029686696 scopus 로고    scopus 로고
    • Evolution of the neuropathology of Alzheimer's disease
    • Braak, H., and Braak, E. (1996). Evolution of the neuropathology of Alzheimer's disease. Acta Neurol. Scand. Suppl. 165, 3-12.
    • (1996) Acta Neurol. Scand. Suppl. , vol.165 , pp. 3-12
    • Braak, H.1    Braak, E.2
  • 7
    • 30344449775 scopus 로고    scopus 로고
    • Competitive interactions between endogenous LTD and LTP in the hippocampus underlie the storage of emotional memories and stress-induced amnesia
    • Diamond, D. M., Park, C. R., Campbell, A. M., and Woodson, J. C. (2005). Competitive interactions between endogenous LTD and LTP in the hippocampus underlie the storage of emotional memories and stress-induced amnesia. Hippocam-pus15, 1006-1025.
    • (2005) Hippocam-pus , vol.15 , pp. 1006-1025
    • Diamond, D.M.1    Park, C.R.2    Campbell, A.M.3    Woodson, J.C.4
  • 8
    • 5344226327 scopus 로고    scopus 로고
    • Rites of passage of the engram: Reconsolidation and the lingering consolidation hypothesis
    • Dudai, Y., and Eisenberg, M. (2004). Rites of passage of the engram: reconsolidation and the lingering consolidation hypothesis. Neuron 44, 93-100.
    • (2004) Neuron , vol.44 , pp. 93-100
    • Dudai, Y.1    Eisenberg, M.2
  • 9
    • 16844363453 scopus 로고    scopus 로고
    • Does lithium therapy protect against the onset of dementia?
    • Dunn, N., Holmes, C., and Mullee, M. (2005). Does lithium therapy protect against the onset of dementia? Alzheimer Dis. Assoc. Disord. 19, 20-22.
    • (2005) Alzheimer Dis. Assoc. Disord. , vol.19 , pp. 20-22
    • Dunn, N.1    Holmes, C.2    Mullee, M.3
  • 10
    • 0042932365 scopus 로고    scopus 로고
    • Stability of retrieved memory: Inverse correlation with trace dominance
    • Eisenberg, M., Kobilo, T., Berman, D. E., and Dudai, Y. (2003). Stability of retrieved memory: inverse correlation with trace dominance. Science 301, 1102-1104.
    • (2003) Science , vol.301 , pp. 1102-1104
    • Eisenberg, M.1    Kobilo, T.2    Berman, D.E.3    Dudai, Y.4
  • 11
    • 84857429142 scopus 로고    scopus 로고
    • GSK-3 inhibitors: Preclini-cal and clinical focus on CNS
    • doi: 10.3389/ fnmol.2011.00032
    • Eldar-Finkelman, H., and Martinez, A. (2011). GSK-3 inhibitors: preclini-cal and clinical focus on CNS. Front. Mol. Neurosci. 4:32. doi: 10.3389/ fnmol.2011.00032
    • (2011) Front. Mol. Neurosci. , vol.4 , pp. 32
    • Eldar-Finkelman, H.1    Martinez, A.2
  • 12
    • 33845530335 scopus 로고    scopus 로고
    • Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert
    • Engel, T., Goni-Oliver, P., Lucas, J. J., Avila, J., and Hernandez, F. (2006). Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert. J. Neurochem. 99, 1445-1455.
    • (2006) J. Neurochem. , vol.99 , pp. 1445-1455
    • Engel, T.1    Goni-Oliver, P.2    Lucas, J.J.3    Avila, J.4    Hernandez, F.5
  • 13
    • 79955546563 scopus 로고    scopus 로고
    • Disease-modifying properties of long-term lithium treatment for amnestic mild cognitive impairment: Randomised controlled trial
    • Forlenza, O. V., Diniz, B. S., Radanovic, M., Santos, F. S., Talib, L. L., and Gat-taz, W. F. (2011). Disease-modifying properties of long-term lithium treatment for amnestic mild cognitive impairment: randomised controlled trial. Br. J. Psychiatry 198, 351-356.
    • (2011) Br. J. Psychiatry , vol.198 , pp. 351-356
    • Forlenza, O.V.1    Diniz, B.S.2    Radanovic, M.3    Santos, F.S.4    Talib, L.L.5    Gat-taz, W.F.6
  • 14
    • 84856702223 scopus 로고    scopus 로고
    • Inhibition of GSK3 by lithium, from single molecules to signaling networks
    • doi: 10.3389/fnmol.2012.00014
    • Freland, L., and Beaulieu, J. M. (2012). Inhibition of GSK3 by lithium, from single molecules to signaling networks. Front. Mol. Neurosci. 5:14. doi: 10.3389/fnmol.2012.00014
    • (2012) Front. Mol. Neurosci. , vol.5 , pp. 14
    • Freland, L.1    Beaulieu, J.M.2
  • 15
    • 84655162701 scopus 로고    scopus 로고
    • Twenty years of Alzheimer's disease-causing mutations
    • Goate, A., and Hardy, J. (2011). Twenty years of Alzheimer's disease-causing mutations. J. Neurochem. Suppl. 1, 3-8.
    • (2011) J. Neurochem. Suppl. , vol.1 , pp. 3-8
    • Goate, A.1    Hardy, J.2
  • 17
    • 45749151056 scopus 로고    scopus 로고
    • Animal models of Alzheimer's disease and frontotemporal dementia
    • Gotz, J., and Ittner, L. M. (2008). Animal models of Alzheimer's disease and frontotemporal dementia. Nat. Rev. Neurosci. 9, 532-544.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 532-544
    • Gotz, J.1    Ittner, L.M.2
  • 18
    • 33745466932 scopus 로고    scopus 로고
    • Targeting glycogen synthase kinase-3 in the CNS: Implications for the development of new treatments for mood disorders
    • Gould, T. D., Picchini, A. M., Einat, H., and Manji, H. K. (2006). Targeting glycogen synthase kinase-3 in the CNS: implications for the development of new treatments for mood disorders. Curr. Drug Targets 7, 1399-1409.
    • (2006) Curr. Drug Targets , vol.7 , pp. 1399-1409
    • Gould, T.D.1    Picchini, A.M.2    Einat, H.3    Manji, H.K.4
  • 20
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy, J., and Selkoe, D. J. (2002). The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297, 353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 21
    • 1642363745 scopus 로고    scopus 로고
    • Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments
    • Hernandez, F., Borrell, J., Guaza, C., Avila, J., and Lucas, J. J. (2002). Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments. J. Neurochem. 83, 1529-1533.
    • (2002) J. Neurochem. , vol.83 , pp. 1529-1533
    • Hernandez, F.1    Borrell, J.2    Guaza, C.3    Avila, J.4    Lucas, J.J.5
  • 22
    • 0034612636 scopus 로고    scopus 로고
    • Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
    • Hoeflich, K. P., Luo, J., Rubie, E. A., Tsao, M. S., Jin, O., and Woodgett, J. R. (2000). Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 406, 86-90.
    • (2000) Nature , vol.406 , pp. 86-90
    • Hoeflich, K.P.1    Luo, J.2    Rubie, E.A.3    Tsao, M.S.4    Jin, O.5    Woodgett, J.R.6
  • 25
    • 0028787686 scopus 로고
    • Different localization of tau protein kinase I/glycogen synthase kinase-3 beta from glycogen synthase kinase-3 alpha in cerebellum mitochondria
    • Hoshi, M., Sato, M., Kondo, S., Takashima, A., Noguchi, K., Taka-hashi, M., Ishiguro, K., and Imahori, K. (1995). Different localization of tau protein kinase I/glycogen synthase kinase-3 beta from glycogen synthase kinase-3 alpha in cerebellum mitochondria. J. Biochem. 118, 683-685.
    • (1995) J. Biochem. , vol.118 , pp. 683-685
    • Hoshi, M.1    Sato, M.2    Kondo, S.3    Takashima, A.4    Noguchi, K.5    Taka-hashi, M.6    Ishiguro, K.7    Imahori, K.8
  • 26
    • 0023675999 scopus 로고
    • A novel tubulin-dependent protein kinase forming a paired helical filament epitope on tau
    • Ishiguro, K., Ihara, Y., Uchida, T., and Imahori, K. (1988). A novel tubulin-dependent protein kinase forming a paired helical filament epitope on tau. J. Biochem. 104, 319-321.
    • (1988) J. Biochem. , vol.104 , pp. 319-321
    • Ishiguro, K.1    Ihara, Y.2    Uchida, T.3    Imahori, K.4
  • 27
    • 0027255817 scopus 로고
    • Glycogen synthase kinase 3 beta is identical to tau protein kinase I generating several epitopes of paired helical filaments
    • Ishiguro, K., Shiratsuchi, A., Sato, S., Omori, A., Arioka, M., Kobayashi, S., Uchida, T., and Imahori, K. (1993). Glycogen synthase kinase 3 beta is identical to tau protein kinase I generating several epitopes of paired helical filaments. FEBS Lett. 325, 167-172.
    • (1993) FEBS Lett. , vol.325 , pp. 167-172
    • Ishiguro, K.1    Shiratsuchi, A.2    Sato, S.3    Omori, A.4    Arioka, M.5    Kobayashi, S.6    Uchida, T.7    Imahori, K.8
  • 28
    • 0035929240 scopus 로고    scopus 로고
    • An important role of neural activity-dependent CaMKIV signaling in the consolidation of long-term memory
    • Kang, H., Sun, L. D., Atkins, C. M., Soderling, T. R., Wilson, M. A., and Tonegawa, S. (2001). An important role of neural activity-dependent CaMKIV signaling in the consolidation of long-term memory. Cell 106, 771-783.
    • (2001) Cell , vol.106 , pp. 771-783
    • Kang, H.1    Sun, L.D.2    Atkins, C.M.3    Soderling, T.R.4    Wilson, M.A.5    Tonegawa, S.6
  • 30
    • 37149046340 scopus 로고    scopus 로고
    • Hyperphos-phorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau
    • Kimura, T., Yamashita, S., Fukuda, T., Park, J. M., Murayama, M., Mizoroki, T., Yoshiike, Y., Sahara, N., and Takashima, A. (2007). Hyperphos-phorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau. EMBO J. 26, 5143-5152.
    • (2007) EMBO J. , vol.26 , pp. 5143-5152
    • Kimura, T.1    Yamashita, S.2    Fukuda, T.3    Park, J.M.4    Murayama, M.5    Mizoroki, T.6    Yoshiike, Y.7    Sahara, N.8    Takashima, A.9
  • 32
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect oflithium on development
    • Klein, P. S., and Melton, D. A. (1996). A molecular mechanism for the effect oflithium on development. Proc. Natl. Acad. Sci. U.S.A. 93, 8455-8459.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 33
    • 33749183270 scopus 로고    scopus 로고
    • Reconsolidation and extinction of conditioned fear: Inhibition and potentiation
    • Lee, J. L. C., Milton, A. L., and Everitt, B. J. (2006). Reconsolidation and extinction of conditioned fear: inhibition and potentiation. J. Neurosci. 26, 10051-10056.
    • (2006) J. Neurosci. , vol.26 , pp. 10051-10056
    • Lee, J.L.C.1    Milton, A.L.2    Everitt, B.J.3
  • 34
    • 77049116286 scopus 로고    scopus 로고
    • Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology
    • Leroy, K., Ando, K., Heraud, C., Yil-maz, Z., Authelet, M., Boeynaems, J. M., Buee, L., De Decker, R., and Brion, J. P. (2010). Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology. J. Alzheimers Dis. 19, 705-719.
    • (2010) J. Alzheimers Dis. , vol.19 , pp. 705-719
    • Leroy, K.1    Ando, K.2    Heraud, C.3    Yil-maz, Z.4    Authelet, M.5    Boeynaems, J.M.6    Buee, L.7    De Decker, R.8    Brion, J.P.9
  • 35
    • 0035863188 scopus 로고    scopus 로고
    • Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
    • Lucas, J. J., Hernandez, F., Gomez-Ramos, P., Moran, M. A., Hen, R., and Avila, J. (2001). Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBOJ. 20, 27-39.
    • (2001) EMBOJ. , vol.20 , pp. 27-39
    • Lucas, J.J.1    Hernandez, F.2    Gomez-Ramos, P.3    Moran, M.A.4    Hen, R.5    Avila, J.6
  • 40
    • 33646164170 scopus 로고    scopus 로고
    • Memory reconsolidation: Sensitivity of spatial memoryto inhibition of protein synthesis in dorsal hippocampus during encoding and retrieval
    • Morris, R. G. M., Inglis, J., Ainge, J. A., Olverman, H. J., Tulloch, J., Dudai, Y., and Kelly, P. A. T. (2006). Memory reconsolidation: sensitivity of spatial memoryto inhibition of protein synthesis in dorsal hippocampus during encoding and retrieval. Neuron 50, 479-489.
    • (2006) Neuron , vol.50 , pp. 479-489
    • Morris, R.G.M.1    Inglis, J.2    Ainge, J.A.3    Olverman, H.J.4    Tulloch, J.5    Dudai, Y.6    Kelly, P.A.T.7
  • 41
    • 0034571503 scopus 로고    scopus 로고
    • The labile nature of consolidation theory
    • Nader, K., Schafe, G. E., and Ledoux, J. E. (2000). The labile nature of consolidation theory. Nat. Rev. Neurosci. 1, 216-219.
    • (2000) Nat. Rev. Neurosci. , vol.1 , pp. 216-219
    • Nader, K.1    Schafe, G.E.2    Ledoux, J.E.3
  • 43
    • 84862845965 scopus 로고    scopus 로고
    • Evaluation of visual recognition memory for the early diagnosis of Alzheimer's disease in patients over 75 years
    • doi: 10.1016/j.neurol.2011.11.004 [Epub ahead of print]
    • Poissonnet, A., Henry-Feugeas, M. C., Drunat, O., Wolmark, Y., Delpierre, S., and Koskas, P. (2012). Evaluation of visual recognition memory for the early diagnosis of Alzheimer's disease in patients over 75 years. Rev. Neurol. doi: 10.1016/j.neurol.2011.11.004 [Epub ahead of print].
    • (2012) Rev. Neurol.
    • Poissonnet, A.1    Henry-Feugeas, M.C.2    Drunat, O.3    Wolmark, Y.4    Delpierre, S.5    Koskas, P.6
  • 44
    • 84856858645 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is an intermediate modulator of serotonin neurotransmission
    • doi: 10.3389/fnmol. 2011.00031
    • Polter, A. M., and Li, X. (2011). Glycogen synthase kinase-3 is an intermediate modulator of serotonin neurotransmission. Front. Mol. Neurosci. 4:31. doi: 10.3389/fnmol. 2011.00031
    • (2011) Front. Mol. Neurosci. , vol.4 , pp. 31
    • Polter, A.M.1    Li, X.2
  • 47
    • 34248181511 scopus 로고    scopus 로고
    • Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model
    • Roberson, E. D., Scearce-Levie, K., Palop, J. J., Yan, F., Cheng, I. H., Wu, T., Gerstein, H., Yu, G. Q., and Mucke, L. (2007). Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science 316, 750-754.
    • (2007) Science , vol.316 , pp. 750-754
    • Roberson, E.D.1    Scearce-Levie, K.2    Palop, J.J.3    Yan, F.4    Cheng, I.H.5    Wu, T.6    Gerstein, H.7    Yu, G.Q.8    Mucke, L.9
  • 50
    • 0022869529 scopus 로고
    • Altered structural proteins in plaques and tangles: What do they tell us about the biology of Alzheimer's disease?
    • Selkoe, D. J. (1986). Altered structural proteins in plaques and tangles: what do they tell us about the biology of Alzheimer's disease? Neurobiol. Aging 7, 425-432.
    • (1986) Neurobiol. Aging , vol.7 , pp. 425-432
    • Selkoe, D.J.1
  • 52
    • 33646519920 scopus 로고    scopus 로고
    • Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy
    • Spires, T. L., Orne, J. D., Santacruz, K., Pitstick, R., Carlson, G. A., Ashe, K. H., and Hyman, B. T. (2006). Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy. Am. J. Pathol. 168, 1598-1607.
    • (2006) Am. J. Pathol. , vol.168 , pp. 1598-1607
    • Spires, T.L.1    Orne, J.D.2    Santacruz, K.3    Pitstick, R.4    Carlson, G.A.5    Ashe, K.H.6    Hyman, B.T.7
  • 53
    • 49149120285 scopus 로고    scopus 로고
    • Hyperphospho-rylated tau is a cause of neuronal dysfunction in tauopathy
    • Takashima, A. (2008). Hyperphospho-rylated tau is a cause of neuronal dysfunction in tauopathy. J. Alzheimers Dis. 14, 371-375.
    • (2008) J. Alzheimers Dis. , vol.14 , pp. 371-375
    • Takashima, A.1
  • 54
    • 0030044463 scopus 로고    scopus 로고
    • Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivationofphosphatidylinositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta
    • Takashima, A., Noguchi, K., Michel, G., Mercken, M., Hoshi, M., Ishiguro, K., and Imahori, K. (1996). Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivationofphosphatidylinositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta. Neurosci. Lett. 203, 33-36.
    • (1996) Neurosci. Lett. , vol.203 , pp. 33-36
    • Takashima, A.1    Noguchi, K.2    Michel, G.3    Mercken, M.4    Hoshi, M.5    Ishiguro, K.6    Imahori, K.7
  • 56
    • 0033864011 scopus 로고    scopus 로고
    • Molecular genetics of Alzheimer's disease: The role of beta-amyloid and the presenilins
    • Tandon, A., Rogaeva, E., Mullan, M., and St George-Hyslop, P. H. (2000). Molecular genetics of Alzheimer's disease: the role of beta-amyloid and the presenilins. Curr. Opin. Neurol. 13, 377-384.
    • (2000) Curr. Opin. Neurol. , vol.13 , pp. 377-384
    • Tandon, A.1    Rogaeva, E.2    Mullan, M.3    St George-Hyslop, P.H.4
  • 57
    • 0030446363 scopus 로고    scopus 로고
    • The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory
    • Tsien, J. Z., Huerta, P. T., and Tone-gawa, S. (1996). The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory. Cell 87, 1327-1338.
    • (1996) Cell , vol.87 , pp. 1327-1338
    • Tsien, J.Z.1    Huerta, P.T.2    Tone-gawa, S.3
  • 58
    • 0037041426 scopus 로고    scopus 로고
    • Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
    • Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., andSelkoe, D. J. (2002). Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416, 535-539.
    • (2002) Nature , vol.416 , pp. 535-539
    • Walsh, D.M.1    Klyubin, I.2    Fadeeva, J.V.3    Cullen, W.K.4    Anwyl, R.5    Wolfe, M.S.6    Rowan, M.J.7    Selkoe, D.J.8
  • 60
    • 0025286104 scopus 로고
    • Molecular cloning and expression of glycogen synthase kinase-3/factor A
    • Woodgett, J. R. (1990). Molecular cloning and expression of glycogen synthase kinase-3/factor A. EMBO J. 8, 2431-2438.
    • (1990) EMBO J. , vol.8 , pp. 2431-2438
    • Woodgett, J.R.1
  • 61
    • 79959276349 scopus 로고    scopus 로고
    • Long-term treatment with lithium alleviates memory deficits and reduces amyloid-beta production in an aged Alzheimer's disease transgenic mouse model
    • Zhang, X., Heng, X., Li, T., Li, L., Yang, D., Du, Y., Doody, R. S., and Le, W. (2011). Long-term treatment with lithium alleviates memory deficits and reduces amyloid-beta production in an aged Alzheimer's disease transgenic mouse model. J. Alzheimers Dis. 24, 739-749.
    • (2011) J. Alzheimers Dis. , vol.24 , pp. 739-749
    • Zhang, X.1    Heng, X.2    Li, T.3    Li, L.4    Yang, D.5    Du, Y.6    Doody, R.S.7    Le, W.8


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