-
1
-
-
0009859038
-
Viral vaccine production in cell culture
-
Spier RE, ed., New York: Wiley & Sons
-
Aunins JG. Viral vaccine production in cell culture. In: Spier RE, ed. Encyclopedia of Cell Technology. Vol. 2. New York: Wiley & Sons, 2000:1182-1217.
-
(2000)
Encyclopedia of Cell Technology
, vol.2
, pp. 1182-1217
-
-
Aunins, J.G.1
-
2
-
-
0032425872
-
Historical reflections on cell culture engineering
-
Lubiniecki AS. Historical reflections on cell culture engineering. Cytotechnology 1998; 28:139-145.
-
(1998)
Cytotechnology
, vol.28
, pp. 139-145
-
-
Lubiniecki, A.S.1
-
3
-
-
0002619214
-
Animal cell products, overview
-
Spier RE, ed., New York: Wiley & Sons
-
Griffiths B. Animal cell products, overview. In: Spier RE, ed. Encyclopedia of Cell Technology. Vol. 1. New York: Wiley & Sons, 2000:70-76.
-
(2000)
Encyclopedia of Cell Technology
, vol.1
, pp. 70-76
-
-
Griffiths, B.1
-
4
-
-
0035313635
-
Industrial choices for protein production by large-scale cell culture
-
Chu L, Robinson DK. Industrial choices for protein production by large-scale cell culture. Curr Opin Biotechnol 2001; 12:180-187.
-
(2001)
Curr Opin Biotechnol
, vol.12
, pp. 180-187
-
-
Chu, L.1
Robinson, D.K.2
-
5
-
-
0018823572
-
Methods for growth of cultured cells in serum-free medium
-
Barnes D, Sato G. Methods for growth of cultured cells in serum-free medium. Anal Biochem 1980; 102:255-270.
-
(1980)
Anal Biochem
, vol.102
, pp. 255-270
-
-
Barnes, D.1
Sato, G.2
-
6
-
-
0020630974
-
Development of a serum-free medium which supports the long-term growth of human and nonhuman primate lymphoid cells
-
Brown RL, Griffith RL, Neubauer RH, Rabin H. Development of a serum-free medium which supports the long-term growth of human and nonhuman primate lymphoid cells. J Cell Physiol 1983; 115:191-198.
-
(1983)
J Cell Physiol
, vol.115
, pp. 191-198
-
-
Brown, R.L.1
Griffith, R.L.2
Neubauer, R.H.3
Rabin, H.4
-
7
-
-
0017751848
-
Clonal growth of Chinese hamster cells in protein-free media
-
Hamilton WG, Ham RG. Clonal growth of Chinese hamster cells in protein-free media. In Vitro 1977; 13:537-547.
-
(1977)
Vitro
, vol.13
, pp. 537-547
-
-
Hamilton, W.G.1
Ham, R.G.2
-
8
-
-
0026039271
-
Nutrient optimization for high density biological production applications
-
Jayme DW. Nutrient optimization for high density biological production applications. Cytotechnology 1991; 5:15-30.
-
(1991)
Cytotechnology
, vol.5
, pp. 15-30
-
-
Jayme, D.W.1
-
9
-
-
85134952927
-
Roles of phosphoethanoamine, ethanolamine, and prolactin in mammary cell growth
-
Surbasku DA, Pardee AB, Salo G, eds, Cold Spring Harbor Conferences on Cell Proliferation
-
Kano-Sueoka T, Errick JE. Roles of phosphoethanoamine, ethanolamine, and prolactin in mammary cell growth. In: Surbasku DA, Pardee AB, Salo G, eds. Growth of Cells in Hormonally Defined Media. Cold Spring Harbor Conferences on Cell Proliferation, 1982:221-230.
-
(1982)
Growth of Cells in Hormonally Defined Media
, pp. 221-230
-
-
Kano-Sueoka, T.1
Errick, J.E.2
-
10
-
-
0020626248
-
Development of a serum-free medium for growth of NS-1 mouse myeloma cells and its application to the isolation of NS-1 hybridomas
-
Kawamoto T, Sato JD, Le A, McClure DB, Sato GH. Development of a serum-free medium for growth of NS-1 mouse myeloma cells and its application to the isolation of NS-1 hybridomas. Anal Biochem 1983; 130:445-453.
-
(1983)
Anal Biochem
, vol.130
, pp. 445-453
-
-
Kawamoto, T.1
Sato, J.D.2
Le, A.3
McClure, D.B.4
Sato, G.H.5
-
11
-
-
0004155427
-
-
3rd ed. New York: W.H. Freeman and Company
-
Stryer L. Biochemistry. 3rd ed. New York: W.H. Freeman and Company, 1988.
-
(1988)
Biochemistry
-
-
Stryer, L.1
-
12
-
-
0019332614
-
The pentose cycle: Control and essential function in HeLa cell nucleic acid synthesis
-
Reitzer LJ, Wice BM, Kennell D. The pentose cycle: control and essential function in HeLa cell nucleic acid synthesis. J Biol Chem 1980; 255:5616-5626.
-
(1980)
J Biol Chem
, vol.255
, pp. 5616-5626
-
-
Reitzer, L.J.1
Wice, B.M.2
Kennell, D.3
-
13
-
-
0025876396
-
Mechanistic stoichiometry of mitochondrial oxidative phosphorylation
-
Hinkle PC, Kumar MA, Resetar A, Harris DL. Mechanistic stoichiometry of mitochondrial oxidative phosphorylation. Biochemistry 1991; 30:3576-3582.
-
(1991)
Biochemistry
, vol.30
, pp. 3576-3582
-
-
Hinkle, P.C.1
Kumar, M.A.2
Resetar, A.3
Harris, D.L.4
-
14
-
-
0023645209
-
Determination of the P=2e_stoichiometries at the individual coupling sites in mitochondrial oxidative phosphorylation
-
Stoner CD. Determination of the P=2e_stoichiometries at the individual coupling sites in mitochondrial oxidative phosphorylation. J Biol Chem 1987; 262:10445-10453.
-
(1987)
J Biol Chem
, vol.262
, pp. 10445-10453
-
-
Stoner, C.D.1
-
15
-
-
0026416508
-
The influence of temperature on amouse-mouse hybridoma growth and monoclonal antibody production
-
SureshkumarGK, Mutharasan R. The influence of temperature on amouse-mouse hybridoma growth and monoclonal antibody production. Biotechnol Bioeng 1991; 37:292-295.
-
(1991)
Biotechnol Bioeng
, vol.37
, pp. 292-295
-
-
Sureshkumar, G.K.1
Mutharasan, R.2
-
16
-
-
0342378192
-
Fermentor temperature as a tool for control of highdensity perfusion cultures of mammalian cells
-
Chuppa S, Tsai Y-S, Yoon S, Shackleford S, Rozales C, Bhat R, Tsay G, Matanguihan C, Konstantinov K, Naveh D. Fermentor temperature as a tool for control of highdensity perfusion cultures of mammalian cells. Biotechnol Bioeng 1997; 55:328-338.
-
(1997)
Biotechnol Bioeng
, vol.55
, pp. 328-338
-
-
Chuppa, S.1
Tsai, Y.-S.2
Yoon, S.3
Shackleford, S.4
Rozales, C.5
Bhat, R.6
Tsay, G.7
Matanguihan, C.8
Konstantinov, K.9
Naveh, D.10
-
17
-
-
0028708951
-
Low temperature cultivation-a step towards process optimization
-
Weidemann R, Ludwig A, Kretzmer G. Low temperature cultivation-a step towards process optimization. Cytotechnology 1994; 15:111-116.
-
(1994)
Cytotechnology
, vol.15
, pp. 111-116
-
-
Weidemann, R.1
Ludwig, A.2
Kretzmer, G.3
-
18
-
-
2142698199
-
Carbohydrate and energy metabolism
-
Willmer EN, ed, New York: Academic Press
-
Paul J. Carbohydrate and energy metabolism. In: Willmer EN, ed. Cells and Tissues in Culture. New York: Academic Press, 1965:239-276.
-
(1965)
Cells and Tissues in Culture
, pp. 239-276
-
-
Paul, J.1
-
19
-
-
84988106827
-
A kinetics analysis of hybridoma growth and metabolism in batch and continuous suspension culture: Effect of nutrient concentration, dilution rate, and pH
-
Miller W, Blanch H, Wilke C. A kinetics analysis of hybridoma growth and metabolism in batch and continuous suspension culture: effect of nutrient concentration, dilution rate, and pH. Biotechnol Bioeng 1988; 32:947-965.
-
(1988)
Biotechnol Bioeng
, vol.32
, pp. 947-965
-
-
Miller, W.1
Blanch, H.2
Wilke, C.3
-
20
-
-
0026254349
-
Growth, metabolic, and antibody production kinetics of hybridoma cell culture: 2. Effects of serum concentration, dissolved oxygen concentration, and medium pH in a batch reactor
-
Ozturk SS, Palsson BO. Growth, metabolic, and antibody production kinetics of hybridoma cell culture: 2. Effects of serum concentration, dissolved oxygen concentration, and medium pH in a batch reactor. Biotechnol Prog 1991; 7:481-494.
-
(1991)
Biotechnol Prog
, vol.7
, pp. 481-494
-
-
Ozturk, S.S.1
Palsson, B.O.2
-
21
-
-
0025001352
-
Hybridoma growth, metabolism, and product formation in Hepes-buffered medium: II. Effect of pH
-
Schmid G, Blanch HW, Wilke CR. Hybridoma growth, metabolism, and product formation in Hepes-buffered medium: II. Effect of pH. Biotechnol Lett 1990; 12:633-638.
-
(1990)
Biotechnol Lett
, vol.12
, pp. 633-638
-
-
Schmid, G.1
Blanch, H.W.2
Wilke, C.R.3
-
22
-
-
0015086239
-
Effect of pH on the growth cycle of HeLa cells in batch suspension culture without oxygen control
-
Barton ME. Effect of pH on the growth cycle of HeLa cells in batch suspension culture without oxygen control. Biotechnol Bioeng 1971; 13:471-492.
-
(1971)
Biotechnol Bioeng
, vol.13
, pp. 471-492
-
-
Barton, M.E.1
-
23
-
-
0001400895
-
The utilization of carbohydrates by human cell cultures
-
Eagle H, Barran S, Levy M, Schulze HO. The utilization of carbohydrates by human cell cultures. J Biol Chem 1958; 233:551-558.
-
(1958)
J Biol Chem
, vol.233
, pp. 551-558
-
-
Eagle, H.1
Barran, S.2
Levy, M.3
Schulze, H.O.4
-
24
-
-
0017190769
-
Growth of human diploid fibroblasts in the absence of glucose utilization
-
Zielke HR, Ozand PT, Tyson J, Sevdalian DA, Cornblath M. Growth of human diploid fibroblasts in the absence of glucose utilization. Proc Natl Acad Sci USA 1976; 73:4110-4114.
-
(1976)
Proc Natl Acad Sci USA
, vol.73
, pp. 4110-4114
-
-
Zielke, H.R.1
Ozand, P.T.2
Tyson, J.3
Sevdalian, D.A.4
Cornblath, M.5
-
25
-
-
0021366190
-
Glutamine: A major energy source for cultured mammalian cells
-
Zielke HR, Zielke CL, Ozand PT. Glutamine: a major energy source for cultured mammalian cells. Feder Proc 1984; 43:121-125.
-
(1984)
Feder Proc
, vol.43
, pp. 121-125
-
-
Zielke, H.R.1
Zielke, C.L.2
Ozand, P.T.3
-
26
-
-
0015523719
-
Permeation of glucose by simple and facilitated diffusion by Novikoff rat hepatoma cells in suspension culture and its relationship to glucose metabolism
-
Renner ED, Plagemann PGW, Bernlohr RW. Permeation of glucose by simple and facilitated diffusion by Novikoff rat hepatoma cells in suspension culture and its relationship to glucose metabolism. J Biol Chem 1972; 247:5765-5776.
-
(1972)
J Biol Chem
, vol.247
, pp. 5765-5776
-
-
Renner, E.D.1
Plagemann, P.G.W.2
Bernlohr, R.W.3
-
27
-
-
0018137321
-
Determinants of glycolytic rate in normal and transformed chick embryo fibroblasts
-
Fagan JB, Racker E. Determinants of glycolytic rate in normal and transformed chick embryo fibroblasts. Cancer Res 1978; 38:749-758.
-
(1978)
Cancer Res
, vol.38
, pp. 749-758
-
-
Fagan, J.B.1
Racker, E.2
-
28
-
-
0034607161
-
A high-yielding, generic fedbatch cell culture process for production of recombinant antibodies
-
Sauer PW, Burky JE, Wesson MC, Sternard HD, Qu L. A high-yielding, generic fedbatch cell culture process for production of recombinant antibodies. Biotechnol Bioeng 2000; 67:585-597.
-
(2000)
Biotechnol Bioeng
, vol.67
, pp. 585-597
-
-
Sauer, P.W.1
Burky, J.E.2
Wesson, M.C.3
Sternard, H.D.4
Qu, L.5
-
29
-
-
0032077416
-
Variation of stoichiometric ratios and their correlation for monitoring and control of animal cell cultures
-
Zeng A-P, Hu WS, Deckwer W. Variation of stoichiometric ratios and their correlation for monitoring and control of animal cell cultures. Biotechnol Prog 1998; 14:434-441.
-
(1998)
Biotechnol Prog
, vol.14
, pp. 434-441
-
-
Zeng, A.-P.1
Hu, W.S.2
Deckwer, W.3
-
30
-
-
0019301038
-
Lactate: A major product of glutamine metabolism by human diploid fibroblasts
-
Zielke HR, Sumbilla CM, Sevdalian DA, Hawkins RL, Ozand PT. Lactate: a major product of glutamine metabolism by human diploid fibroblasts. J Cell Physiol 1980; 104:433-441.
-
(1980)
J Cell Physiol
, vol.104
, pp. 433-441
-
-
Zielke, H.R.1
Sumbilla, C.M.2
Sevdalian, D.A.3
Hawkins, R.L.4
Ozand, P.T.5
-
31
-
-
0019457724
-
Amino acids and glucose utilization by different metabolic pathways
-
Lazo PA. Amino acids and glucose utilization by different metabolic pathways. Eur J Biochem 1981; 117:19-25.
-
(1981)
Eur J Biochem
, vol.117
, pp. 19-25
-
-
Lazo, P.A.1
-
33
-
-
0028500473
-
Catabolic control of hybridoma cells by glucose and glutamine limited fed batch cultures
-
Ljunggren J, Haggstrom L. Catabolic control of hybridoma cells by glucose and glutamine limited fed batch cultures. Biotechnol Bioeng 1994; 44:808-818.
-
(1994)
Biotechnol Bioeng
, vol.44
, pp. 808-818
-
-
Ljunggren, J.1
Haggstrom, L.2
-
34
-
-
84996113208
-
Transient responses of hybridoma cells to nutrient additions in continuous culture: 1. Glucose pulse and step changes
-
Miller WM, Wilke CR, Blanch HW. Transient responses of hybridoma cells to nutrient additions in continuous culture: 1. Glucose pulse and step changes. Biotechnol Bioeng 1989; 33:477-486.
-
(1989)
Biotechnol Bioeng
, vol.33
, pp. 477-486
-
-
Miller, W.M.1
Wilke, C.R.2
Blanch, H.W.3
-
35
-
-
9444286985
-
High cell density and high monoclonal antibody production through medium design and rational control in bioreactor
-
Xie L, Wang DIC. High cell density and high monoclonal antibody production through medium design and rational control in bioreactor. Biotechnol Bioeng 1996; 51:725-729.
-
(1996)
Biotechnol Bioeng
, vol.51
, pp. 725-729
-
-
Xie, L.1
Wang, D.I.C.2
-
36
-
-
0032586148
-
Metabolic shifts by nutrient manipulation in continuous cultures of BHK cells
-
Cruz HJ, Moreira JL, Carrondo MJT. Metabolic shifts by nutrient manipulation in continuous cultures of BHK cells. Biotechnol Bioeng 1999; 66:104-113.
-
(1999)
Biotechnol Bioeng
, vol.66
, pp. 104-113
-
-
Cruz, H.J.1
Moreira, J.L.2
Carrondo, M.J.T.3
-
37
-
-
2442479303
-
The significance of glycolysis
-
Graff S, Moser H, Kastner O, Graff AM, Tannenbaum M. The significance of glycolysis. J Natl Cancer Inst 1965; 34:511-519.
-
(1965)
J Natl Cancer Inst
, vol.34
, pp. 511-519
-
-
Graff, S.1
Moser, H.2
Kastner, O.3
Graff, A.M.4
Tannenbaum, M.5
-
38
-
-
0014098391
-
On the significance of glycolysis for cancer growth with special reference to Morris rat heptoma
-
Burk DM, Woods M, Hunter J. On the significance of glycolysis for cancer growth with special reference to Morris rat heptoma. J Natl Cancer Inst 1967; 38:839-863.
-
(1967)
J Natl Cancer Inst
, vol.38
, pp. 839-863
-
-
Burk, D.M.1
Woods, M.2
Hunter, J.3
-
39
-
-
0027112176
-
Effects of lactate concentration on hybridoma culture in lactate-controlled fed-batch operation
-
OmasaT, Higashiyama K, Shioya S, Suga K. Effects of lactate concentration on hybridoma culture in lactate-controlled fed-batch operation. Biotechnol Bioeng 1992; 39:556-564.
-
(1992)
Biotechnol Bioeng
, vol.39
, pp. 556-564
-
-
Omasa, T.1
Higashiyama, K.2
Shioya, S.3
Suga, K.4
-
40
-
-
0034281582
-
The lactate issue revisited: Novel feeding protocols to examine inhibition of cell proliferation and glucose metabolism in hemotopoietic cell cultures
-
Patel SD, Papoutsakis ET, Winter JN, Miller WM. The lactate issue revisited: novel feeding protocols to examine inhibition of cell proliferation and glucose metabolism in hemotopoietic cell cultures. Biotechnol Prog 2000; 16:885-892.
-
(2000)
Biotechnol Prog
, vol.16
, pp. 885-892
-
-
Patel, S.D.1
Papoutsakis, E.T.2
Winter, J.N.3
Miller, W.M.4
-
41
-
-
0024278869
-
Mathematical descriptions of hybridoma culture kinetics: I. initial metabolic rates
-
Glacken MW, Adema E, Sinskey AJ. Mathematical descriptions of hybridoma culture kinetics: I. initial metabolic rates. Biotechnol Bioeng 1988; 32:491-506.
-
(1988)
Biotechnol Bioeng
, vol.32
, pp. 491-506
-
-
Glacken, M.W.1
Adema, E.2
Sinskey, A.J.3
-
43
-
-
0026196692
-
Growth inhibition in animal cell culture the effect of lactate and ammonia
-
Hassell T, Gleave S, Butler M. Growth inhibition in animal cell culture the effect of lactate and ammonia. Appl Biochem Biotechnol 1991; 30:29-41.
-
(1991)
Appl Biochem Biotechnol
, vol.30
, pp. 29-41
-
-
Hassell, T.1
Gleave, S.2
Butler, M.3
-
44
-
-
0026456864
-
The enhancement of specific antibody production rate in glucose- and glutamine-controlled fed-batch culture
-
Omasa T, Ishimoto M, Higashiyama K, Shioya S, Suga K. The enhancement of specific antibody production rate in glucose- and glutamine-controlled fed-batch culture. Cytotechnology 1992; 5:75-84.
-
(1992)
Cytotechnology
, vol.5
, pp. 75-84
-
-
Omasa, T.1
Ishimoto, M.2
Higashiyama, K.3
Shioya, S.4
Suga, K.5
-
45
-
-
0025465312
-
Growth behavior of Chinese hamster ovary cells in a compact loop bioreactor: 2. Effects of medium components and waste products
-
Kurano N, Leist C, Messi F, Kurano S, Fiechter A. Growth behavior of Chinese hamster ovary cells in a compact loop bioreactor: 2. Effects of medium components and waste products. J Biotechnol 1990; 15:113-128.
-
(1990)
J Biotechnol
, vol.15
, pp. 113-128
-
-
Kurano, N.1
Leist, C.2
Messi, F.3
Kurano, S.4
Fiechter, A.5
-
46
-
-
0027910076
-
The effect of the dilution rate on CHO cell physiology and recombinant interferon-D production in glucose-limited chemostat culture
-
Hayter PM, Curling EMA, Gould ML, Baines AJ, Jenkins N, Simon I, Strange PG, Bull AT. The effect of the dilution rate on CHO cell physiology and recombinant interferon-D production in glucose-limited chemostat culture. Biotechnol Bioeng 1993; 42:1077-1085.
-
(1993)
Biotechnol Bioeng
, vol.42
, pp. 1077-1085
-
-
Hayter, P.M.1
Curling, E.M.A.2
Gould, M.L.3
Baines, A.J.4
Jenkins, N.5
Simon, I.6
Strange, P.G.7
Bull, A.T.8
-
47
-
-
0022787791
-
Reduction of waste product excretion via nutrient control: Possible strategies for maximizing product and cell yields on serum in cultures of mammalian cells
-
Glacken MW, Fleischaker RJ, Sinskey AJ. Reduction of waste product excretion via nutrient control: possible strategies for maximizing product and cell yields on serum in cultures of mammalian cells. Biotechnol Bioeng 1986; 28:1376-1389.
-
(1986)
Biotechnol Bioeng
, vol.28
, pp. 1376-1389
-
-
Glacken, M.W.1
Fleischaker, R.J.2
Sinskey, A.J.3
-
48
-
-
0043071950
-
Mammalian cell culture technology: A review from an engineering perspective
-
Thilly WG, ed, London: Butterworths
-
Hu WS, Wang DIC. Mammalian cell culture technology: a review from an engineering perspective. In: Thilly WG, ed. Mammalian Cell Technology. London: Butterworths, 1986:167-198.
-
(1986)
Mammalian Cell Technology
, pp. 167-198
-
-
Hu, W.S.1
Wang, D.I.C.2
-
49
-
-
0028765274
-
Growth characteristics in fed-batch culture of hybridoma cells with control of glucose and glutamine concentrations
-
Kurokawa H, Park YS, Lijima S, Kobayashi T. Growth characteristics in fed-batch culture of hybridoma cells with control of glucose and glutamine concentrations. Biotechnol Bioeng 1994; 44:95-103.
-
(1994)
Biotechnol Bioeng
, vol.44
, pp. 95-103
-
-
Kurokawa, H.1
Park, Y.S.2
Lijima, S.3
Kobayashi, T.4
-
50
-
-
0344563583
-
Adaptive control at low glucose concentration of HEK-293 cell serum-free cultures
-
Siegwart P, Côté J, Male K, Luong JHT, Perrier M, Kamen A. Adaptive control at low glucose concentration of HEK-293 cell serum-free cultures. Biotechnol Prog 1999; 15:608-616.
-
(1999)
Biotechnol Prog
, vol.15
, pp. 608-616
-
-
Siegwart, P.1
Côté, J.2
Male, K.3
Luong, J.H.T.4
Perrier, M.5
Kamen, A.6
-
51
-
-
0028436847
-
Fed-batch cultivation of animal cells using different medium design concepts and feeding strategies
-
Xie L, Wang DIC. Fed-batch cultivation of animal cells using different medium design concepts and feeding strategies. Biotechnol Bioeng 1994; 43:1175-1189.
-
(1994)
Biotechnol Bioeng
, vol.43
, pp. 1175-1189
-
-
Xie, L.1
Wang, D.I.C.2
-
52
-
-
0028436953
-
Stoichiometric analysis of animal cell growth and its application of medium design
-
Xie L, Wang DIC. Stoichiometric analysis of animal cell growth and its application of medium design. Biotechnol Bioeng 1994; 43:1164-1174.
-
(1994)
Biotechnol Bioeng
, vol.43
, pp. 1164-1174
-
-
Xie, L.1
Wang, D.I.C.2
-
53
-
-
0029059493
-
High viable cell concentration fed-batch cultures of hybridoma cells through on-line nutrient feeding
-
Zhou W, Rehm J, Hu W.-S. High viable cell concentration fed-batch cultures of hybridoma cells through on-line nutrient feeding. Biotechnol Bioeng 1995; 46:579-587.
-
(1995)
Biotechnol Bioeng
, vol.46
, pp. 579-587
-
-
Zhou, W.1
Rehm, J.2
Hu, W.-S.3
-
54
-
-
0030571616
-
Energy metabolism and ATP balance in animal cell cultivation using a stoichiometrically based reaction network
-
Xie L, Wang DIC. Energy metabolism and ATP balance in animal cell cultivation using a stoichiometrically based reaction network. Biotechnol Bioeng 1996; 52:591-601.
-
(1996)
Biotechnol Bioeng
, vol.52
, pp. 591-601
-
-
Xie, L.1
Wang, D.I.C.2
-
55
-
-
0042255072
-
Effect of anions on the non-enzymatic desamidation of glutamine
-
Gilbert JB, Price VE, Greenstein JP. Effect of anions on the non-enzymatic desamidation of glutamine. J Biol Chem 1949; 180:209-218.
-
(1949)
J Biol Chem
, vol.180
, pp. 209-218
-
-
Gilbert, J.B.1
Price, V.E.2
Greenstein, J.P.3
-
56
-
-
0000409606
-
Spontaneous decomposition of glutamine in cell culture media
-
Tritsch GL, Moore GE. Spontaneous decomposition of glutamine in cell culture media. Exp Cell Res 1962; 28:360-364.
-
(1962)
Exp Cell Res
, vol.28
, pp. 360-364
-
-
Tritsch, G.L.1
Moore, G.E.2
-
57
-
-
0023698966
-
Glutamine decomposition in DMEM: Effect of pH and serum concentration
-
Lin A, Agrawal P. Glutamine decomposition in DMEM: effect of pH and serum concentration. Biotechnol Lett 1988; 10:695-698.
-
(1988)
Biotechnol Lett
, vol.10
, pp. 695-698
-
-
Lin, A.1
Agrawal, P.2
-
58
-
-
0025397850
-
Chemical decomposition of glutamine in cell culture media:Effect of media type, pH, serum concentration
-
Ozturk SS, Palsson BO. Chemical decomposition of glutamine in cell culture media:effect of media type, pH, serum concentration. Biotechnol Prog 1990; 6:121-128.
-
(1990)
Biotechnol Prog
, vol.6
, pp. 121-128
-
-
Ozturk, S.S.1
Palsson, B.O.2
-
60
-
-
0003702465
-
Regulatory mechanisms of glutamine catabolism
-
Prusiner S, et al., eds, New York: Academic Press
-
Katunuma N, Katsunuma T, Towatari T, Tomino I. Regulatory mechanisms of glutamine catabolism. In: Prusiner S, et al., eds. The Enzymes of Glutamine Metabolism. New York: Academic Press, 1973:227-258.
-
(1973)
The Enzymes of Glutamine Metabolism
, pp. 227-258
-
-
Katunuma, N.1
Katsunuma, T.2
Towatari, T.3
Tomino, I.4
-
61
-
-
0015175596
-
The pathway of glutamine and glutamate oxidation in isolated mitochondria from mammalian cells
-
Kovacevic Z. The pathway of glutamine and glutamate oxidation in isolated mitochondria from mammalian cells. Biochem J 1971; 125:757-763.
-
(1971)
Biochem J
, vol.125
, pp. 757-763
-
-
Kovacevic, Z.1
-
62
-
-
0024645305
-
Mathematical descriptions of hybridoma culture kinetics. III. Simulation of fed-batch bioreactors
-
Glacken MW, Huang C, Sinskey AJ. Mathematical descriptions of hybridoma culture kinetics. III. Simulation of fed-batch bioreactors. J Biotechnol 1989; 10:39-66.
-
(1989)
J Biotechnol
, vol.10
, pp. 39-66
-
-
Glacken, M.W.1
Huang, C.2
Sinskey, A.J.3
-
63
-
-
0019898583
-
Glycolysis, glutaminolysis and cell proliferation
-
McKeehan WL. Glycolysis, glutaminolysis and cell proliferation. Cell Biol Int Rep 1982; 6:635-650.
-
(1982)
Cell Biol Int Rep
, vol.6
, pp. 635-650
-
-
McKeehan, W.L.1
-
64
-
-
0023553597
-
Characterization of amino acid metabolism by cultured rat kidney cells: Study with 15N
-
Nissim I, States B, Yudkoff M, Segal S. Characterization of amino acid metabolism by cultured rat kidney cells: study with 15N. Am J Physiol 1987; 22:F1243-F1252.
-
(1987)
Am J Physiol
, vol.22
, pp. 1243-1252
-
-
Nissim, I.1
States, B.2
Yudkoff, M.3
Segal, S.4
-
66
-
-
0025049177
-
Glutamine limited fed-batch culture reduces ammonium ion production in animal cells
-
Ljunggren J, Haggstrom L. Glutamine limited fed-batch culture reduces ammonium ion production in animal cells. Biotechnol Lett 1990; 12:705-710.
-
(1990)
Biotechnol Lett
, vol.12
, pp. 705-710
-
-
Ljunggren, J.1
Haggstrom, L.2
-
67
-
-
0026484670
-
Glutamine limited fed-batch culture reduces the overflow metabolism of amino acids in myeloma cells
-
Ljunggren J, Haggstrom L. Glutamine limited fed-batch culture reduces the overflow metabolism of amino acids in myeloma cells. Cytotechnology 1992; 8:45-56.
-
(1992)
Cytotechnology
, vol.8
, pp. 45-56
-
-
Ljunggren, J.1
Haggstrom, L.2
-
68
-
-
33646596236
-
Ammonia toxicity, animal cells
-
Flickinger MC, Drew SW, eds, New York: John Wiley & Sons, Inc
-
Ozturk SS. Ammonia toxicity, animal cells. In: Flickinger MC, Drew SW, eds. The Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis, and Bioseparation. New York: John Wiley & Sons, Inc., 1999:121-136.
-
(1999)
The Encyclopedia of Bioprocess Technology: Fermentation, Biocatalysis, and Bioseparation
, pp. 121-136
-
-
Ozturk, S.S.1
-
71
-
-
0025701084
-
Balanced nutrient fortification enables high-density hybridoma cell culture in batch culture
-
Jo EC, Park HJ, Park JM, Kim KH. Balanced nutrient fortification enables high-density hybridoma cell culture in batch culture. Biotechnol Bioeng 1990; 36:717-722.
-
(1990)
Biotechnol Bioeng
, vol.36
, pp. 717-722
-
-
Jo, E.C.1
Park, H.J.2
Park, J.M.3
Kim, K.H.4
-
72
-
-
0025465346
-
The effect of pH on the toxicity of ammonia to a murine hybridoma
-
Doyle A, Butler M. The effect of pH on the toxicity of ammonia to a murine hybridoma. J Biotechnol 1990; 15:91-100.
-
(1990)
J Biotechnol
, vol.15
, pp. 91-100
-
-
Doyle, A.1
Butler, M.2
-
73
-
-
0028393399
-
Ammonia affects the glycosylation patterns of recombinant mouse placental lactogen-I by Chinese hamster ovary cells in a pHdependent manner
-
Borys MC, Linzer DIH, Papoutsakis ET. Ammonia affects the glycosylation patterns of recombinant mouse placental lactogen-I by Chinese hamster ovary cells in a pHdependent manner. Biotechnol Bioeng 1994; 43:505-514.
-
(1994)
Biotechnol Bioeng
, vol.43
, pp. 505-514
-
-
Borys, M.C.1
Linzer, D.I.H.2
Papoutsakis, E.T.3
-
74
-
-
0029636676
-
The effect of ammonia on the O-linked glycosylation of granulocyte colony-stimulated factor produced by Chinese hamster ovary cells
-
Andersen DC, Goochee CF. The effect of ammonia on the O-linked glycosylation of granulocyte colony-stimulated factor produced by Chinese hamster ovary cells. Biotechnol Bioeng 1995; 47:96-105.
-
(1995)
Biotechnol Bioeng
, vol.47
, pp. 96-105
-
-
Andersen, D.C.1
Goochee, C.F.2
-
75
-
-
0028764887
-
Ammonia inhibition of hybridomas propagated in batch, fed-batch, and continuous culture
-
Newland M, Kamal MN, Greenfield PF, Nielsen LK. Ammonia inhibition of hybridomas propagated in batch, fed-batch, and continuous culture. Biotechnol Bioeng 1994; 43:434-438.
-
(1994)
Biotechnol Bioeng
, vol.43
, pp. 434-438
-
-
Newland, M.1
Kamal, M.N.2
Greenfield, P.F.3
Nielsen, L.K.4
-
76
-
-
0027690259
-
Growth, nutrient consumption, and end-product accumulation in SF-9 and BTI-EAA insect cell cultures: Insights into growth limitation and metabolism
-
Bedard A, Tom R, Kamen A. Growth, nutrient consumption, and end-product accumulation in SF-9 and BTI-EAA insect cell cultures: insights into growth limitation and metabolism. Biotechnol Prog 1993; 9:615-624.
-
(1993)
Biotechnol Prog
, vol.9
, pp. 615-624
-
-
Bedard, A.1
Tom, R.2
Kamen, A.3
-
77
-
-
0027952407
-
Influence of ammonium on growth, metabolism, and productivity of a continuous suspension Chinese ovary cell culture
-
Hansen HA, Emborg C. Influence of ammonium on growth, metabolism, and productivity of a continuous suspension Chinese ovary cell culture. Biotechnol Prog 1994; 10:121-124.
-
(1994)
Biotechnol Prog
, vol.10
, pp. 121-124
-
-
Hansen, H.A.1
Emborg, C.2
-
78
-
-
0027942360
-
Glutamine-based dipeptides are utilized in mammalian cell culture by extracellular hydrolysis catalyzed by a specific peptidase
-
Christie A, Butler M. Glutamine-based dipeptides are utilized in mammalian cell culture by extracellular hydrolysis catalyzed by a specific peptidase. J Biotechnol 1994; 37:277-290.
-
(1994)
J Biotechnol
, vol.37
, pp. 277-290
-
-
Christie, A.1
Butler, M.2
-
79
-
-
0033952514
-
Improvement of CHO cell culture medium formulation: Simultaneous substitution of glucose and glutamine
-
Altamirano A, Paredes C, Cairo JJ, Godia F. Improvement of CHO cell culture medium formulation: simultaneous substitution of glucose and glutamine. Biotechnol Prog 2000; 16:69-75.
-
(2000)
Biotechnol Prog
, vol.16
, pp. 69-75
-
-
Altamirano, A.1
Paredes, C.2
Cairo, J.J.3
Godia, F.4
-
80
-
-
14744283551
-
High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker
-
Bebbington CR, Renner G, Thomson S, King D, Abrams D, Yarranton GT. High-level expression of a recombinant antibody from myeloma cells using a glutamine synthetase gene as an amplifiable selectable marker. Bio=Technology, 1992; 10:169-175.
-
(1992)
Bio=Technology
, vol.10
, pp. 169-175
-
-
Bebbington, C.R.1
Renner, G.2
Thomson, S.3
King, D.4
Abrams, D.5
Yarranton, G.T.6
-
81
-
-
0031554884
-
Fed-batch culture of recombinant NS0 myeloma cells with high monoclonal antibody production
-
Zhou W, Chen C, Buckland B, Aunins J. Fed-batch culture of recombinant NS0 myeloma cells with high monoclonal antibody production. Biotechnol Bioeng 1997; 55:783-792.
-
(1997)
Biotechnol Bioeng
, vol.55
, pp. 783-792
-
-
Zhou, W.1
Chen, C.2
Buckland, B.3
Aunins, J.4
-
82
-
-
0033527072
-
The adaptation of BHK cells to a non-ammoniagenic glutamatebased culture medium
-
Christie A, Butler M. The adaptation of BHK cells to a non-ammoniagenic glutamatebased culture medium. Biotechnol Bioeng 1998; 64:298-309.
-
(1998)
Biotechnol Bioeng
, vol.64
, pp. 298-309
-
-
Christie, A.1
Butler, M.2
-
83
-
-
0028989413
-
Nutrient enrichment and in-situ removal of ammonium and lactate through electrical means for suspension hybridoma cultures
-
Chang YHD, Grodzinsky AJ, Wang DIC. Nutrient enrichment and in-situ removal of ammonium and lactate through electrical means for suspension hybridoma cultures. Biotechnol Bioeng 1995; 47:319-326.
-
(1995)
Biotechnol Bioeng
, vol.47
, pp. 319-326
-
-
Chang, Y.H.D.1
Grodzinsky, A.J.2
Wang, D.I.C.3
-
84
-
-
0028888674
-
In-situ removal of ammonium and lactate from suspension hybridoma cultures through electrical means
-
Chang YHD, Grodzinsky AJ, Wang DIC. In-situ removal of ammonium and lactate from suspension hybridoma cultures through electrical means. Biotechnol Bioeng 1995; 47:308-318.
-
(1995)
Biotechnol Bioeng
, vol.47
, pp. 308-318
-
-
Chang, Y.H.D.1
Grodzinsky, A.J.2
Wang, D.I.C.3
-
85
-
-
0001572284
-
Nutrition needs of mammalian cells in tissue culture
-
Eagle H. Nutrition needs of mammalian cells in tissue culture. Science 1955; 122:501-504.
-
(1955)
Science
, vol.122
, pp. 501-504
-
-
Eagle, H.1
-
87
-
-
0001398727
-
Amino acid metabolism in mammalian cell cultures
-
Eagle H. Amino acid metabolism in mammalian cell cultures. Science 1959; 130:432-437.
-
(1959)
Science
, vol.130
, pp. 432-437
-
-
Eagle, H.1
-
88
-
-
0014783871
-
The quantitative utilization of amino acids and glucose and contact inhibition of growth in cultures of the human diploid cell, WI-38
-
Griffiths JB. The quantitative utilization of amino acids and glucose and contact inhibition of growth in cultures of the human diploid cell, WI-38. J Cell Sci 1970; 6:739-749.
-
(1970)
J Cell Sci
, vol.6
, pp. 739-749
-
-
Griffiths, J.B.1
-
89
-
-
0014074674
-
Amino acid utilizations and protein synthesis at various proliferation rates, population densities, and protein contents of perfused animal cell and tissue cultures
-
Kruse PF, Miedema E, Carter HC. Amino acid utilizations and protein synthesis at various proliferation rates, population densities, and protein contents of perfused animal cell and tissue cultures. Biochemistry 1967; 6:949-955.
-
(1967)
Biochemistry
, vol.6
, pp. 949-955
-
-
Kruse, P.F.1
Miedema, E.2
Carter, H.C.3
-
90
-
-
49749211914
-
The amino acid metabolism of differentiating skeletal myoblasts in vitro
-
Lucy JA, Rinaldini LM. The amino acid metabolism of differentiating skeletal myoblasts in vitro. Exp Cell Res 1959; 17:385-398.
-
(1959)
Exp Cell Res
, vol.17
, pp. 385-398
-
-
Lucy, J.A.1
Rinaldini, L.M.2
-
91
-
-
50549172290
-
Selective utilization of amino acids by mammalian cell cultures
-
McCarty K. Selective utilization of amino acids by mammalian cell cultures. Exp Cell Res 1962; 27:230-240.
-
(1962)
Exp Cell Res
, vol.27
, pp. 230-240
-
-
McCarty, K.1
-
92
-
-
84873779293
-
The metabolism of animal tissues cultivated in vitro II. Amino acid metabolism of chick embryonic kidney, chick embryonic liver, and monkey kidney cortex cultures
-
Pasieka AE, Morton HJ, Morgan JF. The metabolism of animal tissues cultivated in vitro II. Amino acid metabolism of chick embryonic kidney, chick embryonic liver, and monkey kidney cortex cultures. Can J Biochem Physiol 1958; 55:171-184.
-
(1958)
Can J Biochem Physiol
, vol.55
, pp. 171-184
-
-
Pasieka, A.E.1
Morton, H.J.2
Morgan, J.F.3
-
93
-
-
84873781206
-
The metabolism of animal tissues cultivated in vitro III. Amino acid metabolism of strain L cells in completely synthetic media
-
Pasieka AE, Morton HJ, Morgan JF. The metabolism of animal tissues cultivated in vitro III. Amino acid metabolism of strain L cells in completely synthetic media. Can J Biochem Physiol 1958; 36:771-782.
-
(1958)
Can J Biochem Physiol
, vol.36
, pp. 771-782
-
-
Pasieka, A.E.1
Morton, H.J.2
Morgan, J.F.3
-
94
-
-
1842273482
-
Uptake and utilization of amino acids by cell cultures
-
Rotbblat GH, Gristofalo VJ, eds, New York: Academic Press
-
Patterson MKJ. Uptake and utilization of amino acids by cell cultures. In: Rotbblat GH, Gristofalo VJ, eds. Growth, Nutrient, and Metabolism of Cells in Culture. New York: Academic Press, 1972:171-209.
-
(1972)
Growth, Nutrient, and Metabolism of Cells in Culture
, pp. 171-209
-
-
Patterson, M.K.J.1
-
95
-
-
49749196265
-
Amino acid and glucose uptake in relation to protein synthesis in cells growing in tissue culture
-
Sinclair R, Leslie I. Amino acid and glucose uptake in relation to protein synthesis in cells growing in tissue culture. Biochim Biophys Acta 1959; 32:58-68.
-
(1959)
Biochim Biophys Acta
, vol.32
, pp. 58-68
-
-
Sinclair, R.1
Leslie, I.2
-
96
-
-
0028474159
-
Transient responses of hybridoma cells in continuous culture to step changes in amino acid vitamin concentrations
-
Hiller GW, Clark DS, Blanch HW. Transient responses of hybridoma cells in continuous culture to step changes in amino acid vitamin concentrations. Biotechnol Bioeng 1994; 44:303-321.
-
(1994)
Biotechnol Bioeng
, vol.44
, pp. 303-321
-
-
Hiller, G.W.1
Clark, D.S.2
Blanch, H.W.3
-
98
-
-
0026219281
-
Factors controlling cell proliferation and antibody production in mouse hybridoma cells: 1. Influence of the amino acid supply
-
Duval A, Demangel C, Munier-Jolain K, Miossec S, Geahel I. Factors controlling cell proliferation and antibody production in mouse hybridoma cells: 1. Influence of the amino acid supply. Biotechnol Bioeng 1991; 38:561-570.
-
(1991)
Biotechnol Bioeng
, vol.38
, pp. 561-570
-
-
Duval, A.1
Demangel, C.2
Munier-Jolain, K.3
Miossec, S.4
Geahel, I.5
-
99
-
-
84996094699
-
The transient responses of hybridoma cells to nutrient additions in continuous culture: II. Glutamine pulse and step changes
-
Miller WM, Wilke CR, Blanch HW. The transient responses of hybridoma cells to nutrient additions in continuous culture: II. Glutamine pulse and step changes. Biotechnol Bioeng 1989; 33:487-499.
-
(1989)
Biotechnol Bioeng
, vol.33
, pp. 487-499
-
-
Miller, W.M.1
Wilke, C.R.2
Blanch, H.W.3
-
100
-
-
0015314673
-
Amino acid utilization by L-M strain mouse cells in a chemically defined medium
-
Stoner GD, Merchant DJ. Amino acid utilization by L-M strain mouse cells in a chemically defined medium. In Vitro 1972; 7:330-343.
-
(1972)
Vitro
, vol.7
, pp. 330-343
-
-
Stoner, G.D.1
Merchant, D.J.2
-
101
-
-
0030571589
-
Material balance studies on animal cell metabolism using a stoichiometrically based reaction network
-
Xie L, Wang DIC. Material balance studies on animal cell metabolism using a stoichiometrically based reaction network. Biotechnol Bioeng 1996; 52:579-590.
-
(1996)
Biotechnol Bioeng
, vol.52
, pp. 579-590
-
-
Xie, L.1
Wang, D.I.C.2
-
102
-
-
0016659515
-
The quantitative requirements of human diploid cells (strain MRC-5) for amino acids, vitamins, and serum
-
Lambert K, Pirt SJ. The quantitative requirements of human diploid cells (strain MRC-5) for amino acids, vitamins, and serum. J Cell Sci 1975; 17:397-411.
-
(1975)
J Cell Sci
, vol.17
, pp. 397-411
-
-
Lambert, K.1
Pirt, S.J.2
-
103
-
-
0003692166
-
-
Redwood City, CA: Benjamin=Cummings Publishing Company, Inc
-
Mathews CK, van Holde KE. Biochemistry. Redwood City, CA: Benjamin=Cummings Publishing Company, Inc., 1990.
-
(1990)
Biochemistry
-
-
Mathews, C.K.1
van Holde, K.E.2
-
105
-
-
0028765767
-
Enhancement of monoclonal antibody yield by hybridoma fed-batch culture, resulting in extended maintenance of viable cell population
-
Bushell ME, Bell SL, Scott MF, Spier RE, Wardell JN, Sanders PG. Enhancement of monoclonal antibody yield by hybridoma fed-batch culture, resulting in extended maintenance of viable cell population. Biotechnol Bioeng 1994; 44:1099-1106.
-
(1994)
Biotechnol Bioeng
, vol.44
, pp. 1099-1106
-
-
Bushell, M.E.1
Bell, S.L.2
Scott, M.F.3
Spier, R.E.4
Wardell, J.N.5
Sanders, P.G.6
-
106
-
-
0002065362
-
Feeding strategies for enhanced hybridoma productivity: Automated concentrate supplementation
-
Fike R, Kubiak J, Price P, Jayme D. Feeding strategies for enhanced hybridoma productivity: automated concentrate supplementation. BioPharm 1993; 6:49-54.
-
(1993)
BioPharm
, vol.6
, pp. 49-54
-
-
Fike, R.1
Kubiak, J.2
Price, P.3
Jayme, D.4
-
107
-
-
0034606665
-
Multiple steady states with distinct cellular metabolism in continuous culture of mammalian cells
-
Europa AF, Gambhir A, Fu PC, Hu WS. Multiple steady states with distinct cellular metabolism in continuous culture of mammalian cells. Biotechnol Bioeng 2000; 67:25-34.
-
(2000)
Biotechnol Bioeng
, vol.67
, pp. 25-34
-
-
Europa, A.F.1
Gambhir, A.2
Fu, P.C.3
Hu, W.S.4
-
108
-
-
0028693147
-
Applications of improved stoichiometric model in medium design and fed-batch cultivation of animal cells in bioreactor
-
Xie L, Wang DIC. Applications of improved stoichiometric model in medium design and fed-batch cultivation of animal cells in bioreactor. Cytotechnology 1994; 15:17-29.
-
(1994)
Cytotechnology
, vol.15
, pp. 17-29
-
-
Xie, L.1
Wang, D.I.C.2
-
109
-
-
0034281747
-
293SF metabolic flux analysis during cell growth and infection with an adenoviral vector
-
Nadeau I, Jacob D, Perrier M, Kamen A. 293SF metabolic flux analysis during cell growth and infection with an adenoviral vector. Biotechnol Prog 2000; 16:872-884.
-
(2000)
Biotechnol Prog
, vol.16
, pp. 872-884
-
-
Nadeau, I.1
Jacob, D.2
Perrier, M.3
Kamen, A.4
-
110
-
-
0034511786
-
Human 293 cell metabolism in low glutamine-supplied culture: Interpretation of metabolic changes through metabolic flux analysis
-
Nadeau I, Sabatie J, Koehl M, Perrier M, Kamen A. Human 293 cell metabolism in low glutamine-supplied culture: interpretation of metabolic changes through metabolic flux analysis. Metab Eng 2000; 2:277-292.
-
(2000)
Metab Eng
, vol.2
, pp. 277-292
-
-
Nadeau, I.1
Sabatie, J.2
Koehl, M.3
Perrier, M.4
Kamen, A.5
-
111
-
-
0004020626
-
-
2nd ed. Palo Alto, CA: W.A. Benjamin
-
Lehninger AL. Bioenergetics. 2nd ed. Palo Alto, CA: W.A. Benjamin, 1965.
-
(1965)
Bioenergetics
-
-
Lehninger, A.L.1
-
112
-
-
0031555512
-
Gamma-interferon production and quality in stoichiometric fed-batch cultures of Chinese hamster ovary (CHO) cells under serum-free conditions
-
Xie L, Nyberg G, Gu X, Li H, Mollborn F, Wang DIC. Gamma-interferon production and quality in stoichiometric fed-batch cultures of Chinese hamster ovary (CHO) cells under serum-free conditions. Biotechnol Bioeng 1997; 56:577-582.
-
(1997)
Biotechnol Bioeng
, vol.56
, pp. 577-582
-
-
Xie, L.1
Nyberg, G.2
Gu, X.3
Li, H.4
Mollborn, F.5
Wang, D.I.C.6
-
113
-
-
0017760332
-
The independent distribution of amino acid near neighbor pairs into polypeptides
-
Klapper MH. The independent distribution of amino acid near neighbor pairs into polypeptides. Biochem Biophys Res Commun 1977; 78:1018-1024.
-
(1977)
Biochem Biophys Res Commun
, vol.78
, pp. 1018-1024
-
-
Klapper, M.H.1
-
115
-
-
0014736579
-
An improved chemically defined culture medium for strain L mouse cells based on growth responses to graded levels of nutrients including iron and zinc ions
-
Higuchi K. An improved chemically defined culture medium for strain L mouse cells based on growth responses to graded levels of nutrients including iron and zinc ions. J Cell Physiol 1970; 75:65-72.
-
(1970)
J Cell Physiol
, vol.75
, pp. 65-72
-
-
Higuchi, K.1
-
116
-
-
0034609598
-
Phosphate feeding improves highcell- concentration NS0 myeloma culture performance for monoclonal antibody production
-
deZengotita VM, Miller WM, Aunins JG, Zhou W. Phosphate feeding improves highcell- concentration NS0 myeloma culture performance for monoclonal antibody production. Biotechnol Bioeng 2000; 69:566-576.
-
(2000)
Biotechnol Bioeng
, vol.69
, pp. 566-576
-
-
deZengotita, V.M.1
Miller, W.M.2
Aunins, J.G.3
Zhou, W.4
-
118
-
-
0002043589
-
-
Rogers KR, Mulchandani A, Zhou W, eds. Biosensor and Chemical Sensor Technology:Process Monitoring and Control. ACS Symposium Series 613. Washington, DC:American Chemical Society
-
Zhou W, Mulchandani A. Recent advances in bioprocess monitoring and control. In: Rogers KR, Mulchandani A, Zhou W, eds. Biosensor and Chemical Sensor Technology:Process Monitoring and Control. ACS Symposium Series 613. Washington, DC:American Chemical Society, 1995:88-98.
-
(1995)
Recent advances in bioprocess monitoring and control
, pp. 88-98
-
-
Zhou, W.1
Mulchandani, A.2
-
119
-
-
85134984318
-
-
Ho CS, Wang, DIC, eds. Animal Cell Bioreactors. Stoneham: Butterworth-Heinemann
-
Glacken MW. Bioreactor control and optimization. In: Ho CS, Wang, DIC, eds. Animal Cell Bioreactors. Stoneham: Butterworth-Heinemann, 1991.
-
(1991)
Bioreactor control and optimization
-
-
Glacken, M.W.1
-
120
-
-
0026656091
-
On-line measurements in biotechnology: Techniques
-
Loch G, Sonnleitner B, Fiechter A. On-line measurements in biotechnology: Techniques. J Biotechnol 1992; 25:23-53.
-
(1992)
J Biotechnol
, vol.25
, pp. 23-53
-
-
Loch, G.1
Sonnleitner, B.2
Fiechter, A.3
-
121
-
-
84978647173
-
Common instruments for process analysis and control
-
Schügerl, K, eds., New York: VCH
-
Schügerl K. Common instruments for process analysis and control. In: Schügerl, K, eds. Biotechnology. Vol. 4. New York: VCH, 1991:5-25.
-
(1991)
Biotechnology
, vol.4
, pp. 5-25
-
-
Schügerl, K.1
-
122
-
-
84952879158
-
On-line analysis of broth
-
Schügerl K, ed., New York: VCH
-
Schügerl K. On-line analysis of broth. In: Schügerl K, ed. Biotechnology. Vol. 4. New York: VCH, 1991:149-180.
-
(1991)
Biotechnology
, vol.4
, pp. 149-180
-
-
Schügerl, K.1
-
123
-
-
0025984702
-
Instrumentation of animal cell culture reactors
-
Ho CS, Wang DIC, eds, Stoneham: Butterworth-Heinemann
-
Scheirer W, Merten OW. Instrumentation of animal cell culture reactors. In: Ho CS, Wang DIC, eds. Animal Cell Bioreactors. Stoneham: Butterworth-Heinemann, 1991:405-443.
-
(1991)
Animal Cell Bioreactors
, pp. 405-443
-
-
Scheirer, W.1
Merten, O.W.2
-
124
-
-
85134971935
-
On-line analysis in animal cell culture
-
Spier RE, ed., New York: Wiley & Sons
-
Kretzmer G. On-line analysis in animal cell culture. In: Spier RE, ed. Encyclopedia of Cell Technology. Vol. 2. New York: Wiley & Sons, 2000:968-978.
-
(2000)
Encyclopedia of Cell Technology
, vol.2
, pp. 968-978
-
-
Kretzmer, G.1
-
125
-
-
0035809780
-
On-line determination of animal cell concentration
-
Ducommun P, Bolzonella I, Rhiel M, Pugeaud P, von Stockar U, Marison IW. On-line determination of animal cell concentration. Biotechnol Bioeng 2001; 72:515-522.
-
(2001)
Biotechnol Bioeng
, vol.72
, pp. 515-522
-
-
Ducommun, P.1
Bolzonella, I.2
Rhiel, M.3
Pugeaud, P.4
von Stockar, U.5
Marison, I.W.6
-
126
-
-
0027112178
-
Fed-batch culture automated by use of continuously measured cell concentration and cell volume
-
Yamane T, Hibino W, Ishihara K, Kadotani Y, Kominami M. Fed-batch culture automated by use of continuously measured cell concentration and cell volume. Biotechnol Bioeng 1992; 39:550-555.
-
(1992)
Biotechnol Bioeng
, vol.39
, pp. 550-555
-
-
Yamane, T.1
Hibino, W.2
Ishihara, K.3
Kadotani, Y.4
Kominami, M.5
-
127
-
-
0027338535
-
Application of an on-line turbidimeter for the automation of fed-batch cultures
-
Yamane T. Application of an on-line turbidimeter for the automation of fed-batch cultures. Biotechnol Prog 1993; 9:81-85.
-
(1993)
Biotechnol Prog
, vol.9
, pp. 81-85
-
-
Yamane, T.1
-
128
-
-
0027003334
-
On-line monitoring of hybridoma cell growth using a laser turbidity sensor
-
Konstantinov KB, Pambayun R, Matanguihan R, Yoshida T, Perusich CM, Hu WS. On-line monitoring of hybridoma cell growth using a laser turbidity sensor. Biotechnol Bioeng 1992; 40:1337-1342.
-
(1992)
Biotechnol Bioeng
, vol.40
, pp. 1337-1342
-
-
Konstantinov, K.B.1
Pambayun, R.2
Matanguihan, R.3
Yoshida, T.4
Perusich, C.M.5
Hu, W.S.6
-
129
-
-
0028454939
-
On-line characterization of a hybridoma cell culture process
-
Zhou W, Hu WS. On-line characterization of a hybridoma cell culture process. Biotechnol Bioeng 1994; 44:170-177.
-
(1994)
Biotechnol Bioeng
, vol.44
, pp. 170-177
-
-
Zhou, W.1
Hu, W.S.2
-
130
-
-
0029256472
-
Evaluation and applications of optical cell density probes in mammalian cell bioreactors
-
Wu P, Ozturk SS, Blackie JD, Thrift JC, Figueroa C, Daveh D. Evaluation and applications of optical cell density probes in mammalian cell bioreactors. Biotechnol Bioeng 1995; 45:495-502.
-
(1995)
Biotechnol Bioeng
, vol.45
, pp. 495-502
-
-
Wu, P.1
Ozturk, S.S.2
Blackie, J.D.3
Thrift, J.C.4
Figueroa, C.5
Daveh, D.6
-
131
-
-
85134940584
-
-
Oral presentation at Biochemical Engineering XII, Rohnert Park, CA
-
Scheper T, Staerk E, Hitzmann B, Boehl D, Lindemann C. 2-D Spectrofluorometry for bioprocess monitoring and control. Oral presentation at Biochemical Engineering XII, Rohnert Park, CA, 2001.
-
(2001)
2-D Spectrofluorometry for bioprocess monitoring and control
-
-
Scheper, T.1
Staerk, E.2
Hitzmann, B.3
Boehl, D.4
Lindemann, C.5
-
132
-
-
0032487328
-
In situ microscopy for on-line determination of biomass
-
Bittner C, Wehnert G, Scheper T. In situ microscopy for on-line determination of biomass. Biotechnol Bioeng 1998; 60:24-35.
-
(1998)
Biotechnol Bioeng
, vol.60
, pp. 24-35
-
-
Bittner, C.1
Wehnert, G.2
Scheper, T.3
-
133
-
-
0028694522
-
Automated monitoring of cell concentration and viability using an image analysis system
-
Maruhashi F, Murakami S, Baba K. Automated monitoring of cell concentration and viability using an image analysis system. Cytotechnology 1994; 15:281-289.
-
(1994)
Cytotechnology
, vol.15
, pp. 281-289
-
-
Maruhashi, F.1
Murakami, S.2
Baba, K.3
-
134
-
-
84913471522
-
Aseptic sampling
-
Christiansen C, Munck L, Villadsen J, eds., Copenhagen: Munksgaard
-
Schügerl K. Aseptic sampling. In: Christiansen C, Munck L, Villadsen J, eds. Proceedings of the 5th European Congress on Biotechnology. Vol. 2. Copenhagen: Munksgaard, 1990:1188-1193.
-
(1990)
Proceedings of the 5th European Congress on Biotechnology
, vol.2
, pp. 1188-1193
-
-
Schügerl, K.1
-
135
-
-
0026162116
-
On-line monitoring of monoclonal antibody formation in high density perfusion culture using FIA
-
Fenge C, Fraune E, Freitag R, Scheper T, Schügerl K. On-line monitoring of monoclonal antibody formation in high density perfusion culture using FIA. Cytotechnol 1991; 6:55-63.
-
(1991)
Cytotechnol
, vol.6
, pp. 55-63
-
-
Fenge, C.1
Fraune, E.2
Freitag, R.3
Scheper, T.4
Schügerl, K.5
-
136
-
-
0024962307
-
A flow injection analysis system for fermentation monitoring and control
-
Garn M, Gisin M, Thommen C. A flow injection analysis system for fermentation monitoring and control. Biotechnol Bioeng 1989; 34:423-428.
-
(1989)
Biotechnol Bioeng
, vol.34
, pp. 423-428
-
-
Garn, M.1
Gisin, M.2
Thommen, C.3
-
137
-
-
0025950715
-
Enzyme sensor-FIA-system for on-line monitoring of glucose, lactate and glutamine in animal cell cultures
-
Renneberg R, Trott-Kriegeskorte G, Lietz M, Jaeger V, Pawlowa M, Kaiser G, Wollenberger U, Schubert F, Wagner R, et al. Enzyme sensor-FIA-system for on-line monitoring of glucose, lactate and glutamine in animal cell cultures. J Biotechnol 1991; 21:173-85.
-
(1991)
J Biotechnol
, vol.21
, pp. 173-185
-
-
Renneberg, R.1
Trott-Kriegeskorte, G.2
Lietz, M.3
Jaeger, V.4
Pawlowa, M.5
Kaiser, G.6
Wollenberger, U.7
Schubert, F.8
Wagner, R.9
-
138
-
-
0026481940
-
Chemiluminescence fiber-optic biosensor system for the determination of glutamine in mammalian cell cultures
-
Cattaneo MV, Male KB, Luong JHT. Chemiluminescence fiber-optic biosensor system for the determination of glutamine in mammalian cell cultures. Biosensors Bioelectron 1992; 7:569-574.
-
(1992)
Biosensors Bioelectron
, vol.7
, pp. 569-574
-
-
Cattaneo, M.V.1
Male, K.B.2
Luong, J.H.T.3
-
139
-
-
0026525809
-
On-line determination of glucose and lactate concentrations in animal cell culture based on fiber optic detection of oxygen in flow-injection analysis
-
Dremel BAA, Li SY, Schmid RD. On-line determination of glucose and lactate concentrations in animal cell culture based on fiber optic detection of oxygen in flow-injection analysis. Biosensors Bioelectron 1992; 7:133-139.
-
(1992)
Biosensors Bioelectron
, vol.7
, pp. 133-139
-
-
Dremel, B.A.A.1
Li, S.Y.2
Schmid, R.D.3
-
140
-
-
0027024625
-
Determination of urinary glucose by a flow injection analysis amperometric biosensor and ion-exchange chromatography
-
Male KB, Luong JHT et al. Determination of urinary glucose by a flow injection analysis amperometric biosensor and ion-exchange chromatography. Appl Biochem Biotechnol 1992; 37:243-254.
-
(1992)
Appl Biochem Biotechnol
, vol.37
, pp. 243-254
-
-
Male, K.B.1
Luong, J.H.T.2
-
141
-
-
0027334699
-
Chemiluminescent flow injection analysis of glucose in drinks with a bienzyme fiberoptic biosensor
-
Blum LJ. Chemiluminescent flow injection analysis of glucose in drinks with a bienzyme fiberoptic biosensor. Enzyme Microb Technol 1993; 15:407-411.
-
(1993)
Enzyme Microb Technol
, vol.15
, pp. 407-411
-
-
Blum, L.J.1
-
142
-
-
0027595077
-
On-line chemiluminescent assay using FIA and fiber optics for urinary and blood glucose
-
Cattaneo MV, Luong JHT. On-line chemiluminescent assay using FIA and fiber optics for urinary and blood glucose. Enzyme Microb Technol 1993; 15:424-428.
-
(1993)
Enzyme Microb Technol
, vol.15
, pp. 424-428
-
-
Cattaneo, M.V.1
Luong, J.H.T.2
-
143
-
-
0027571742
-
Monitoring glutamine in animal cell cultures using a chemiluminescent fiber optic biosensor
-
Cattaneo MV, Luong JHT. Monitoring glutamine in animal cell cultures using a chemiluminescent fiber optic biosensor. Biotechnol Bioeng 1993; 41:659-665.
-
(1993)
Biotechnol Bioeng
, vol.41
, pp. 659-665
-
-
Cattaneo, M.V.1
Luong, J.H.T.2
-
144
-
-
0027454847
-
Novel FIA amperometric biosensor system for the determination of glutamine in cell culture system
-
Male KB, Luong JHT, Tom R, Mercille S. Novel FIA amperometric biosensor system for the determination of glutamine in cell culture system. Enzyme Microb Technol 1993; 15:26-32.
-
(1993)
Enzyme Microb Technol
, vol.15
, pp. 26-32
-
-
Male, K.B.1
Luong, J.H.T.2
Tom, R.3
Mercille, S.4
-
145
-
-
0027588171
-
Simultaneous enzymatic= electrochemical determination of glucose and l-glutamine in hybridoma media by flow-injection analysis
-
Meyerhoff EM, Trojanowicz KM, Palsson OB. Simultaneous enzymatic= electrochemical determination of glucose and l-glutamine in hybridoma media by flow-injection analysis. Biotechnol Bioeng 1993; 41:964-969.
-
(1993)
Biotechnol Bioeng
, vol.41
, pp. 964-969
-
-
Meyerhoff, E.M.1
Trojanowicz, K.M.2
Palsson, O.B.3
-
146
-
-
0028693802
-
Automated immunoanalysis systems for monitoring mammalian cell cultivation processes
-
Schulze B, Middendorf C, Reinecke M, Scheper T. Automated immunoanalysis systems for monitoring mammalian cell cultivation processes. Cytotechnology 1994; 15:259-269.
-
(1994)
Cytotechnology
, vol.15
, pp. 259-269
-
-
Schulze, B.1
Middendorf, C.2
Reinecke, M.3
Scheper, T.4
-
147
-
-
85134964581
-
The automation of two immune-FIAsystems using the flexible software system CAFCA
-
Rogers KR, Mulchandani A, Zhou W, eds, ACS Symposium Series 613. Washington, DC: American Chemical Society
-
Hitzmann B, Schulze B, Reinecke M, Scheper T. The automation of two immune-FIAsystems using the flexible software system CAFCA. In: Rogers KR, Mulchandani A, Zhou W, eds. Biosensor and Chemical Sensor Technology: Process Monitoring and Contro. ACS Symposium Series 613. Washington, DC: American Chemical Society, 1995:165-175.
-
(1995)
Biosensor and Chemical Sensor Technology: Process Monitoring and Contro
, pp. 165-175
-
-
Hitzmann, B.1
Schulze, B.2
Reinecke, M.3
Scheper, T.4
-
148
-
-
0035811187
-
Integrated flow-injection processing for on-line quantification of plasmid DNA during cultivation of E. coli
-
Nandakumar MP, Karlsson EN, Mattiasson B. Integrated flow-injection processing for on-line quantification of plasmid DNA during cultivation of E. coli. Biotechnol Bioeng 2001; 73:406-411.
-
(2001)
Biotechnol Bioeng
, vol.73
, pp. 406-411
-
-
Nandakumar, M.P.1
Karlsson, E.N.2
Mattiasson, B.3
-
149
-
-
0028816849
-
On-line calibration of a computerized biosensor system for continuous measurements of glucose and lactate
-
Kyröläinen M, Hakanson H, Mattiasson B. On-line calibration of a computerized biosensor system for continuous measurements of glucose and lactate. Biotechnol Bioeng 1995; 45:122-128.
-
(1995)
Biotechnol Bioeng
, vol.45
, pp. 122-128
-
-
Kyröläinen, M.1
Hakanson, H.2
Mattiasson, B.3
-
150
-
-
0006088586
-
An expert system for the supervision of a multi channel flow injection analysis system
-
Rogers KR, Mulchandani A, Zhou W, eds, ACS SymposiumSeries 613. Washington, DC:American Chemical Society
-
Hitzmann B, Gomersall R, Brandt J, van Putten A. An expert system for the supervision of a multi channel flow injection analysis system. In: Rogers KR, Mulchandani A, Zhou W, eds. Biosensor and Chemical Sensor Technology: Process Monitoring and Contro. ACS SymposiumSeries 613. Washington, DC:American Chemical Society, 1995:133-143.
-
(1995)
Biosensor and Chemical Sensor Technology: Process Monitoring and Contro
, pp. 133-143
-
-
Hitzmann, B.1
Gomersall, R.2
Brandt, J.3
van Putten, A.4
-
151
-
-
0001726669
-
Off-line analysis in animal cell culture, methods
-
Spier RE, ed., New York: Wiley & Sons
-
Buentemeyer H. Off-line analysis in animal cell culture, methods. In: Spier RE, ed. Encyclopedia of Cell Technology. Vol. 2. New York: Wiley & Sons, 2000:945-959.
-
(2000)
Encyclopedia of Cell Technology
, vol.2
, pp. 945-959
-
-
Buentemeyer, H.1
-
152
-
-
0025057156
-
On-line high-performance liquid chromatography for determination of cephalosporin C and by-products in complex fermentation broth
-
Holzhauer-Rieger K, Zhou W, Schügerl K. On-line high-performance liquid chromatography for determination of cephalosporin C and by-products in complex fermentation broth. J Chromatogr 1990; 499:609-615.
-
(1990)
J Chromatogr
, vol.499
, pp. 609-615
-
-
Holzhauer-Rieger, K.1
Zhou, W.2
Schügerl, K.3
-
153
-
-
0026656092
-
Present and potential applications of mass spectrometry for bioprocess research and control
-
Heinzle E. Present and potential applications of mass spectrometry for bioprocess research and control. J Biotechnol 1992; 25:81-114.
-
(1992)
J Biotechnol
, vol.25
, pp. 81-114
-
-
Heinzle, E.1
-
154
-
-
0028066753
-
Use of on-line gas analysis to monitor recombinant mammalian cell cultures
-
Lovrecz G, Gray P. Use of on-line gas analysis to monitor recombinant mammalian cell cultures. Cytotechnology 1994; 14:167-175.
-
(1994)
Cytotechnology
, vol.14
, pp. 167-175
-
-
Lovrecz, G.1
Gray, P.2
-
155
-
-
0029256482
-
Determination of the respiration quotient in mammalian cell culture in bicarbonate buffered media
-
Bonarius HPJ, de Gooijer CD, Tramper J, Schmid G. Determination of the respiration quotient in mammalian cell culture in bicarbonate buffered media. Biotechnol Bioeng 1995; 45:524-535.
-
(1995)
Biotechnol Bioeng
, vol.45
, pp. 524-535
-
-
Bonarius, H.P.J.1
de Gooijer, C.D.2
Tramper, J.3
Schmid, G.4
-
156
-
-
0023720546
-
Large-scale production of monoclonal antibodies in suspension culture
-
Backer MP, Metzger LS, Slaber PL, Nevitt KL, Boder GB. Large-scale production of monoclonal antibodies in suspension culture. Biotechnol Bioeng 1988; 32:993-1000.
-
(1988)
Biotechnol Bioeng
, vol.32
, pp. 993-1000
-
-
Backer, M.P.1
Metzger, L.S.2
Slaber, P.L.3
Nevitt, K.L.4
Boder, G.B.5
-
157
-
-
0028008437
-
Mass spectrometry: A tool for on-line monitoring of animal cell cultures
-
Behrendt U, Koch S, Gooch DD, Steegmans U, Comer MJ. Mass spectrometry: a tool for on-line monitoring of animal cell cultures. Cytotechnology 1994; 14:157-165.
-
(1994)
Cytotechnology
, vol.14
, pp. 157-165
-
-
Behrendt, U.1
Koch, S.2
Gooch, D.D.3
Steegmans, U.4
Comer, M.J.5
-
158
-
-
0028979470
-
On-line gas analysis in animal cell cultivation: I. Control of dissolved oxygen and pH
-
Oeggerli A, Eyer K, Heinzle E. On-line gas analysis in animal cell cultivation: I. Control of dissolved oxygen and pH. Biotechnol Bioeng 1995; 45:42-53.
-
(1995)
Biotechnol Bioeng
, vol.45
, pp. 42-53
-
-
Oeggerli, A.1
Eyer, K.2
Heinzle, E.3
-
159
-
-
0029635979
-
On-line gas analysis in animal cell cultivation: II. Methods for oxygen uptake rate estimation and its application to controlled feeding of glutamine
-
Eyer K, Oeggerli A, Heinzle E. On-line gas analysis in animal cell cultivation: II. Methods for oxygen uptake rate estimation and its application to controlled feeding of glutamine. Biotechnol Bioeng 1995; 45:54-62.
-
(1995)
Biotechnol Bioeng
, vol.45
, pp. 54-62
-
-
Eyer, K.1
Oeggerli, A.2
Heinzle, E.3
-
161
-
-
0025499794
-
Cell cycle- and growth phase-dependent variations in size distribution, antibody productivity, and oxygen demand in hybridoma cultures
-
Ramirez OT, Mutharasen R. Cell cycle- and growth phase-dependent variations in size distribution, antibody productivity, and oxygen demand in hybridoma cultures. Biotechnol Bioeng 1990; 36:839-848.
-
(1990)
Biotechnol Bioeng
, vol.36
, pp. 839-848
-
-
Ramirez, O.T.1
Mutharasen, R.2
-
163
-
-
0028137616
-
Expert systems in the control of animal cell culture processes: Potentials, functions, and perspectives
-
Konstantinov KB, Zhou W, Golini F, Hu WS. Expert systems in the control of animal cell culture processes: potentials, functions, and perspectives. Cytotechnology 1994; 14:233-246.
-
(1994)
Cytotechnology
, vol.14
, pp. 233-246
-
-
Konstantinov, K.B.1
Zhou, W.2
Golini, F.3
Hu, W.S.4
-
164
-
-
85134959971
-
-
Galindo E, Ramirez OT, eds. Advances in Bioprocess Engineering. Proceedings of the International Symposium on Bioprocess Engineering. Cuernavaca, Mexico, June 20-24. Dordrecht: Kluwer
-
Zhou W, Hu WS. Optimization of fed-batch mammalian cell culture processe. In: Galindo E, Ramirez OT, eds. Advances in Bioprocess Engineering. Proceedings of the International Symposium on Bioprocess Engineering. Cuernavaca, Mexico, June 20-24. Dordrecht: Kluwer, 1994.
-
(1994)
Optimization of fed-batch mammalian cell culture processe
-
-
Zhou, W.1
Hu, W.S.2
-
165
-
-
0030916886
-
Alteration of mammalian cell metabolism by dynamic nutrient feeding
-
Zhou W, Rehm J, Europa A, Hu WS. Alteration of mammalian cell metabolism by dynamic nutrient feeding. Cytotechnology 1997; 24:99-108.
-
(1997)
Cytotechnology
, vol.24
, pp. 99-108
-
-
Zhou, W.1
Rehm, J.2
Europa, A.3
Hu, W.S.4
-
166
-
-
0030440863
-
Large scale production of recombinant mouse and rat growth hormone by fed-batch GS-NS0 cell cultures
-
Zhou W, Bibila TB, Glazomitsky K, Montalvo J, Chan CP, DiStefano DJ, Munshi S, Robinson DK, Buckland BC, Aunins JG. Large scale production of recombinant mouse and rat growth hormone by fed-batch GS-NS0 cell cultures. Cytotechnology 1996; 22:239-250.
-
(1996)
Cytotechnology
, vol.22
, pp. 239-250
-
-
Zhou, W.1
Bibila, T.B.2
Glazomitsky, K.3
Montalvo, J.4
Chan, C.P.5
DiStefano, D.J.6
Munshi, S.7
Robinson, D.K.8
Buckland, B.C.9
Aunins, J.G.10
-
168
-
-
0034609271
-
A systematic approach to the validation of process control parameters for monoclonal antibody production in fed-batch culture of a murine myeloma
-
Moran EB, McGowan ST, McGuire JM, Frankland JE, Oyebade IA, Waller W, Archer LC, Morris LO, Pandya J, Nathan SR, Smith L, Cadette ML, Michalowski JT. A systematic approach to the validation of process control parameters for monoclonal antibody production in fed-batch culture of a murine myeloma. Biotechnol Bioeng 2000; 69:242-255.
-
(2000)
Biotechnol Bioeng
, vol.69
, pp. 242-255
-
-
Moran, E.B.1
McGowan, S.T.2
McGuire, J.M.3
Frankland, J.E.4
Oyebade, I.A.5
Waller, W.6
Archer, L.C.7
Morris, L.O.8
Pandya, J.9
Nathan, S.R.10
Smith, L.11
Cadette, M.L.12
Michalowski, J.T.13
-
169
-
-
0027952406
-
Monoclonal antibody process development using medium concentrates
-
Bibila TA, Ranucci CS, Glazomitsky K, Buckland BC, Aunins JG. Monoclonal antibody process development using medium concentrates. Biotechnol Prog 1994; 10:87-96.
-
(1994)
Biotechnol Prog
, vol.10
, pp. 87-96
-
-
Bibila, T.A.1
Ranucci, C.S.2
Glazomitsky, K.3
Buckland, B.C.4
Aunins, J.G.5
-
170
-
-
0029104088
-
In pursuit of the optimal fed-batch process for monoclonal antibody production
-
Bibila TA, Robinson DK. In pursuit of the optimal fed-batch process for monoclonal antibody production. Biotechnol Prog 1995; 11:1-13.
-
(1995)
Biotechnol Prog
, vol.11
, pp. 1-13
-
-
Bibila, T.A.1
Robinson, D.K.2
-
171
-
-
0008416002
-
Production of engineered antibodies in myeloma and hybridoma cells-enhancements in gene expression and process design
-
Wang H, Imanaka T, eds, American Chemical Society Symposium Series, 604. Washington, DC: American Chemical Society
-
Robinson DK, DiStefano DJ, Gould SL, Cuca G, Seamans TC, Benincasa D, Munshi S, Chan CP, Lee DK, Stafford-Hollis J, Hollis G, Jain D, Ramasubramanyan K, Mark GE, Silberklang M. Production of engineered antibodies in myeloma and hybridoma cells-enhancements in gene expression and process design. In: Wang H, Imanaka T, eds. Antibody Engineerin. American Chemical Society Symposium Series, 604. Washington, DC: American Chemical Society, 1995:1-14.
-
(1995)
Antibody Engineerin
, pp. 1-14
-
-
Robinson, D.K.1
DiStefano, D.J.2
Gould, S.L.3
Cuca, G.4
Seamans, T.C.5
Benincasa, D.6
Munshi, S.7
Chan, C.P.8
Lee, D.K.9
Stafford-Hollis, J.10
Hollis, G.11
Jain, D.12
Ramasubramanyan, K.13
Mark, G.E.14
Silberklang, M.15
-
172
-
-
0008468486
-
Major metabolic changes accompany transfection and selection for high level expression of recombinant genes
-
Gould SL, DiStefano DJ, Cuca G, Robinson DK, Silberklang M. Major metabolic changes accompany transfection and selection for high level expression of recombinant genes. In Vitro Cell Dev Biol 1992; 28:162A.
-
(1992)
Vitro Cell Dev Biol
, vol.28
, pp. 162
-
-
Gould, S.L.1
DiStefano, D.J.2
Cuca, G.3
Robinson, D.K.4
Silberklang, M.5
-
173
-
-
0028765762
-
Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cells
-
Mercille S, Massie B. Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cells. Biotechnol Bioeng 1994; 44:1140-1154.
-
(1994)
Biotechnol Bioeng
, vol.44
, pp. 1140-1154
-
-
Mercille, S.1
Massie, B.2
-
174
-
-
0024237365
-
Effects of proximate cholesterol precursors and steroid hormones on mouse myeloma growth in serum-free medium
-
Sato DJ, Cao HT, Kayada Y, Cabot MC, Sato HH, Okamoto T, Welsh CJ. Effects of proximate cholesterol precursors and steroid hormones on mouse myeloma growth in serum-free medium. In Vitro Cell Dev Biol 1988; 24:1223-1228.
-
(1988)
Vitro Cell Dev Biol
, vol.24
, pp. 1223-1228
-
-
Sato, D.J.1
Cao, H.T.2
Kayada, Y.3
Cabot, M.C.4
Sato, H.H.5
Okamoto, T.6
Welsh, C.J.7
-
175
-
-
0028710426
-
Selecting and designing cell lines for improved physiological characteristics
-
Birch JR, Boraston RC, Metcalfe H, Brown ME, Bebbington CR, Field PR. Selecting and designing cell lines for improved physiological characteristics. Cytotechnology 1994; 15:11-16.
-
(1994)
Cytotechnology
, vol.15
, pp. 11-16
-
-
Birch, J.R.1
Boraston, R.C.2
Metcalfe, H.3
Brown, M.E.4
Bebbington, C.R.5
Field, P.R.6
-
176
-
-
0029173973
-
Adaptation of cholesterol-requiring NS0 mouse myeloma cells to high density growth in a fully defined protein-free and cholesterol-free medium
-
Keen MJ, Steward TW. Adaptation of cholesterol-requiring NS0 mouse myeloma cells to high density growth in a fully defined protein-free and cholesterol-free medium. Cytotechnology 1995; 17:203-211.
-
(1995)
Cytotechnology
, vol.17
, pp. 203-211
-
-
Keen, M.J.1
Steward, T.W.2
-
177
-
-
85134999812
-
-
Presented at the Congress on Cell and Tissue Culture, San Diego, CA
-
Gould SL, DiStefano DJ, Silberklang M, Robinson DK. Serum-free animal cell culture medium development using an automated multi-well growth monitoring device. Presented at the Congress on Cell and Tissue Culture, San Diego, CA, 1993.
-
(1993)
Serum-free animal cell culture medium development using an automated multi-well growth monitoring device
-
-
Gould, S.L.1
DiStefano, D.J.2
Silberklang, M.3
Robinson, D.K.4
-
178
-
-
0029760549
-
Feeding of nutrients delays apoptotic death in fed-batch cultures of NS0 myeloma cells
-
DiStefano DJ, Mark GE, Robinson DK. Feeding of nutrients delays apoptotic death in fed-batch cultures of NS0 myeloma cells. Biotechnol Lett 1996; 18:1067-1072.
-
(1996)
Biotechnol Lett
, vol.18
, pp. 1067-1072
-
-
DiStefano, D.J.1
Mark, G.E.2
Robinson, D.K.3
-
179
-
-
0028979478
-
Starvation-induced programmed cell death of hybridoma cells: Prevention by amino acid mixtures
-
Franek K. Starvation-induced programmed cell death of hybridoma cells: Prevention by amino acid mixtures. Biotechnol Bioeng 1995; 45:86-90.
-
(1995)
Biotechnol Bioeng
, vol.45
, pp. 86-90
-
-
Franek, K.1
-
180
-
-
0000975391
-
Apoptosis and nutrition: Involvement of amino acid transport system in repression of hybridoma cell death
-
Franek F, Chladkova-Sramkova K. Apoptosis and nutrition: involvement of amino acid transport system in repression of hybridoma cell death. Cytotechnology 1995; 18:113-117.
-
(1995)
Cytotechnology
, vol.18
, pp. 113-117
-
-
Franek, F.1
Chladkova-Sramkova, K.2
-
181
-
-
0029048389
-
Overexpression of bcl-2, apoptosis suppressing gene: Prolonged viable culture period of hybridoma and enhanced antibody production
-
Itoh Y, Ueda H, Suzuki E. Overexpression of bcl-2, apoptosis suppressing gene: prolonged viable culture period of hybridoma and enhanced antibody production. Biotechnol Bioeng 1995; 48:118-122.
-
(1995)
Biotechnol Bioeng
, vol.48
, pp. 118-122
-
-
Itoh, Y.1
Ueda, H.2
Suzuki, E.3
-
182
-
-
0030570840
-
NS0 Myeloma cell death:Influence of bcl-2 overexpression
-
Murray K, Ang CE, Gull K, Hickman JA, Dickinson AJ. NS0 Myeloma cell death:influence of bcl-2 overexpression. Biotechnol Bioeng 1996; 51:298-304.
-
(1996)
Biotechnol Bioeng
, vol.51
, pp. 298-304
-
-
Murray, K.1
Ang, C.E.2
Gull, K.3
Hickman, J.A.4
Dickinson, A.J.5
-
183
-
-
0034610095
-
Multiple cell culture factors can affect the glycosylation of Asn-184 in CHO-produced tissue-type plasminogen activator
-
Andersen DC, Bridges T, Gawlitzek M, Hoy C. Multiple cell culture factors can affect the glycosylation of Asn-184 in CHO-produced tissue-type plasminogen activator. Biotechnol Bioeng 2000; 70:25-31.
-
(2000)
Biotechnol Bioeng
, vol.70
, pp. 25-31
-
-
Andersen, D.C.1
Bridges, T.2
Gawlitzek, M.3
Hoy, C.4
-
184
-
-
0034238099
-
Performance of small-scale CHO perfusion cultures using an acoustic cell filtration device for cell retention:Characterization of separation efficiency and impact of perfusion on product quality
-
Ryll T, Dutina G, Reyes A, Gunson J, Krummen L, Etcheverry T. Performance of small-scale CHO perfusion cultures using an acoustic cell filtration device for cell retention:characterization of separation efficiency and impact of perfusion on product quality. Biotechnol Bioeng 2000; 69:440-449.
-
(2000)
Biotechnol Bioeng
, vol.69
, pp. 440-449
-
-
Ryll, T.1
Dutina, G.2
Reyes, A.3
Gunson, J.4
Krummen, L.5
Etcheverry, T.6
-
185
-
-
0034691229
-
Ammonium alters N-glycan structures of recombinant TNFR-IgG: Degradative versus biosynthetic mechanisms
-
Gawlitzek M, Ryll T, Lofgren J, Sliwkowski MB. Ammonium alters N-glycan structures of recombinant TNFR-IgG: degradative versus biosynthetic mechanisms. Biotechnol Bioeng 2000; 68:637-646.
-
(2000)
Biotechnol Bioeng
, vol.68
, pp. 637-646
-
-
Gawlitzek, M.1
Ryll, T.2
Lofgren, J.3
Sliwkowski, M.B.4
-
186
-
-
85134927779
-
-
Oral presentation at Cell Culture Engineering VII, Santa Fe, NM
-
Chang DYH, Seewoester T, Turner BG, Moesta P. Development of a technology platform for production of human monoclonal antibodies in recombinant CHO cell culture. Oral presentation at Cell Culture Engineering VII, Santa Fe, NM, 2000.
-
(2000)
Development of a technology platform for production of human monoclonal antibodies in recombinant CHO cell culture
-
-
Chang, D.Y.H.1
Seewoester, T.2
Turner, B.G.3
Moesta, P.4
-
187
-
-
85134961942
-
-
Oral presentation at 219th American Chemical Society National Meeting, San Francisco, CA
-
Seewoester T, Chang DYH, Turner BG, Moesta P. Development of a generic high-yield fed-batch process for large-scale GMP manufacturing of human monoclonal antibodies. Oral presentation at 219th American Chemical Society National Meeting, San Francisco, CA, 2001
-
(2001)
Development of a generic high-yield fed-batch process for large-scale GMP manufacturing of human monoclonal antibodies
-
-
Seewoester, T.1
Chang, D.Y.H.2
Turner, B.G.3
Moesta, P.4
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