Gamma-interferon production and quality in stoichiometric fed-batch cultures of Chinese hamster ovary (CHO) cells under serum-free conditions

Biotechnology and Bioengineering

Volumn 56, Issue 5, 1997, Pages 577-582

  Xie, Liangzhi ^a,b   Nyberg, Gregg ^a   Gu, Xuejun ^a   Li, Hanyuan ^a   Möllborn, Fredrik ^a   Wang, Daniel I C ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

CHO cells; Fed batch; Gamma interferon; Glucose starvation; Glycosylation; Nutritional control; Protein quality

Indexed keywords

ANIMAL CELL CULTURE; CELLS; GLUCOSE; INSULIN; INTERFERONS; PROTEINS;

GAMMA-INTERFERON; GLYCOSYLATION;

BATCH CELL CULTURE;

GAMMA INTERFERON;

ANIMAL CELL; ARTICLE; CELL COMPOSITION; CELL CULTURE; CELL GROWTH; CHO CELL; CULTURE MEDIUM; NONHUMAN; STOICHIOMETRY;

EID: 0031555512     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19971205)56:5<577::AID-BIT11>3.0.CO;2-9     Document Type: Article

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