Metabolic engineering of bacteria for food ingredients

Food Biotechnology, Second Edition

Volumn , Issue , 2005, Pages 111-130

  Gonzalez, Ramon ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85134000119     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (74)

1. Bailey, J.E. Toward a science of metabolic engineering. Science 252:1668-1675, 1991.
2. Stephanopoulos, G., A.A. Aristidou, J. Nielsen. Metabolic Engineering: Principles and Methodologies, 1st ed. San Diego, CA: Academic Press, 1998.
3. Mollet, B., I. Rowland. Functional foods: at the frontier between food and pharma. Curr. Opin. Biotech. 13:483-485, 2002.
4. Mueller, U., S. Huebner. Economic aspects of amino acids production. Adv. Biochem. Engin./Biotechnol. 79:137-170, 2003.
5. Leuchtenberger, W. Amino acids: technical production and use. In: Biotechnology, Rehm, H.J., G. Reed, eds., Weinheim, Germany: VCH, 1996, pp 465-502.
6. Ikeda, M. Amino acid production processes. Adv. Biochem. Engin./Biotechnol. 79:1-35, 2003.
7. Vallino, J.J., G. Stephanopoulos. Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction. Biotechnol. Bioeng. 41:633-646, 1993.
8. Marx, A., A.A. de Graaf, W. Wiechert, L. Eggeling, H. Sahm. Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing. Biotechnol. Bioeng. 49:111-129, 1996.
9. Ikeda, M., R. Katsumata. Hyperproduction of tryptophan by Corynebacterium glutamicum with the modified pentose phosphate pathway. Appl. Environ. Microbiol. 65:2497-2502, 1999.
10. Ikeda, M., K. Okamoto, T. Nakano, N. Kamada. Production of metabolite biosynthesized through phosphoribosylpyrophosphoric acid. Japan Patent 12,014,396 A, 2000.
11. Ozaki, A., R. Katsumata, T. Oka, A. Furuya. Cloning of the genes concerned in phenylalanine biosynthesis in Corynebacterium glutamicum and its application to breeding of a phenylalanine producing strain. Agric. Biol. Chem. 49:2925-2930, 1985.
12. Ikeda, M., A. Ozaki, R. Katsumata. Phenylalanine production by metabolically engineered Corynebacterium glutamicum with the pheA gene of Escherichia coli. App. Microb. Biotechnol. 39:18-323, 1993.
13. Guillouet, S., A.A. Rodal, G. An, P.A. Lessard, A.J. Sinskey. Expression of the Escherichia coli catabolic threonine dehydratase in Corynebacterium glutamicum and its effect on isoleucine production. Appl. Environ. Microbiol. 65:3100-3107, 1999.
14. Ikeda, M., R. Katsumata. Metabolic engineering to produce tyrosine or phenylalanine in a tryptophan producing Corynebacterium glutamicum strain. App. Environ. Microbiol. 58:781-785, 1992.
15. Katsumata, R., T. Mizukami, Y. Kikuchi, K. Kino. Threonine production by the lysine producing strain of Corynebacterium glutamicum with amplified threonine biosynthetic operon. In: Genetics of Industrial Microorganisms. Proceedings of the Fifth International Symposium on the Genetics of Industrial Microorganisms. Alacevic, M., D. Hranueli, Z. Toman, eds., Karlovac, Yugoslavia: Ognjen Prica Printing Works, 1987, pp 217-250.
16. Ikeda, M., K. Nakanishi, K. Kino, R Katsumata. Fermentative production of tryptophan by a stable recombinant strain of Corynebacterium glutamicum with a modified serinebiosynthethic pathway. Biosci. Biotechnol. Biochem. 58:674-678, 1994.
17. Ikeda, M., R. Katsumata. Tryptophan production by transport mutants of Corynebacterium glutamicum. Biosci. Biotechnol. Biochem. 59:1600-1602, 1995.
18. Kimura, E. Metabolic Engineering of glutamate production. Adv. Biochem. Engin./Biotechnol. 79:37-57, 2003.
19. Pfefferle, W., B. Möckel, B. Bathe, A. Marx. Biotechnological manufacture of lysine. Adv. Biochem. Engin./Biotechnol. 79:59-112, 2003.
20. Marx, A., B.J. Eikmanns, H. Sahm, A.A. de Graaf, L. Eggeling. Response of the central metabolism in Corynebacterium glutamicum to the use of an NADH-dependent glutamate dehydrogenase. Metabolic Eng. 1:35-48, 1999.
21. Hols, P., M. Kleerebezem, A.N. Schanck, T. Ferain, J. Hugenholtz, J. Delcour, W.M. de Vos. Conversion of Lactococcus lactis from homolactic to homoalanine fermentation through metabolic engineering. Nat. Biotechnol. 17:588-592, 1999.
22. Clark, D.P., The fermentation pathways of Escherichia coli. FEMS Microbiol. Rev. 63:223-234, 1989.
23. Millard, C.S., Y.P. Chao, J.C. Liao, M.I. Donnelly. Enhanced production of succinic acid by overexpression of phosphoenolpyruvate carboxylase in Escherichia coli. Appl. Environ. Microbiol. 62:1808-1810, 1996.
24. Gokarn, R.R., E. Altman, M.A. Eiteman. Metabolic analysis of Escherichia coli glucose fermentation in presence of pyruvate carboxylase. Biotechnol. Lett. 20:795-798, 1998.
25. Stols, L., M.I. Donnelly. Production of succinic acid through overexpression of NAD+-dependent malic enzyme in an Escherichia coli mutant. Appl. Environ. Microbiol. 63:2695-2701, 1997.
26. Stols, L., G. Kulkarni, B.G. Harris, M.I. Donnelly. Expression of Ascaris suum malic enzyme in a mutant Escherichia coli allows production of succinic acid from glucose. Appl. Biochem. Biotechnol. 63-65:153-158, 1997.
27. Boernke, W.E., C.S. Millard, P.W. Stevens, S.N. Kakar, F.J. Stevens, M.I. Donnelly. Stringency of substrate specificity of Escherichia coli malate dehydrogenase. Arch. Biochem. 322:43-52, 1995.
28. Donnelly, M.I., C.S. Millard, D.P. Clark, M.J. Chen, J.W. Rathke. A novel fermentation pathway in an Escherichia coli mutant producing succinic acid, acetic acid, and ethanol. Appl. Biochem. Biotechnol. 70-72:187-198, 1998.
29. Nghiem, N.P., M. Donnelly, C.S. Millard, L. Stols. Method for the production of dicarboxylic acids. U.S. patent 5,869,301, 1999.
30. Chatterjee, R.C., S. Millard, K. Champion, D.P. Clark, M.I. Donnelly. Mutation of the ptsG gene results in increased production of succinate in fermentation of glucose by Escherichia coli. Appl. Environ. Microbiol. 67:148-154, 2001.
31. Gokarn, R.R., J.D. Evans, J.R. Walker, S.A. Martin, M.A. Eiteman, E. Altman. The physiological effects and metabolic alterations caused by the expression of Rhizobium etli pyruvate carboxylase in Escherichia coli. Appl. Microbiol. Biotechnol. 56:188-195, 2001.
32. Gokarn, R.R., M.A. Eiteman, E. Altman. Metabolic analysis of Escherichia coli in the presence and absence of the carboxylating enzymes phosphoenolpyruvate carboxylase and pyruvate carboxylase. Appl. Environ. Microbiol. 66:1844-1850, 2000.
33. Li,Y., J. Chen, S.-Y. Lun. Biotechnological production of pyruvic acid. Appl. Microbiol. Biotechnol. 57:451-459, 2001.
34. Yokota, A., H. Shimizu, Y. Terasawa, N. Takaoka. Pyruvic acid production by a lipoic acid auxotroph of Escherichia coli W1485. Appl. Microbiol. Biotechnol. 41:638-643, 1994.
35. Yokota, A., Y. Terasawa, N. Takaoka, H. Shimizu, F. Tomita. Pyruvate production by an F1-ATPase-defective mutant of Escherichia coli. Biosci. Biotechnol. Biochem. 58:2164-2167, 1994.
36. Yokota, A., M. Henmi, N. Takaoka, C. Hayashi, Y. Takezawa, Y. Fukumori, F. Tomita. Enhancement of glucose metabolism in a pyruvic acid-hyperproducing Escherichia coli mutant defective in F1-ATPase activity. J. Ferment. Bioeng. 83:132-138, 1997.
37. Koebmann, B.J., H.V. Westerhoff, J.L. Snoep, D. Nilsson, P.R. Jensen. The glycolytic flux in Escherichia coli is controlled by the demand for ATP. J. Bacteriol. 184:3909-3916, 2002.
38. Benthin, S., J. Villadsen. Production of optically pure D-lactate by Lactobacillus bulgaricus and purification by crystallization and liquid/liquid extraction. Appl Microbiol Biotechnol 42:826-829, 1995.
39. Vickroy, T.B., Lactic acid. In: Comprehensive Biotechnology: The Principles, Applications, and Regulations of Biotechnology in Industry, Agriculture and Medicine, Vol. 2. Moo-Young, M., ed., New York: Pergamon Press, 1985, pp 761-776.
40. Stanier, R.Y., J.L. Ingraham, M.L. Wheelis, P.R. Painter. The Microbial World, 5th ed., Englewood Cliffs, NJ: Prentice-Hall, 1986, pp 495-504.
41. Chang, D.E., H.C. Jung, J.S. Rhee, J.G. Pan. Homofermentative production of D- or L-lactate in metabolically engineered Escherichia coli RR1. Appl. Environ. Microbiol. 65:1384-1389, 1999.
42. Zhou, S., T.B. Causey, A. Hasona, K.T. Shanmugam, L.O. Ingram. Production of optically pure D-lactic acid in mineral salts medium by metabolically engineered Escherichia coli W3110. Appl. Environ. Microbiol. 69:399-407, 2002.
43. Skory, C.D. Isolation and expression of lactate dehydrogenase genes from Rhizopus oryzae. Appl. Environ. Microbiol. 66:2343-2348, 2000.
44. Ohara, H., H. Okuyama, S. Sawa, Y. Fujii, K. Hiyama. Development of industrial production of high molecular weight poly-L-lactate from renewable resources. Nippon Kagaku Kaishi 6:323-331, 2001.
45. Causey, T.B., S. Zhou, K.T. Shanmugam, L.O. Ingram. Inaugural article: engineering the metabolism of Escherichia coli W3110 for the conversion of sugar to redox-neutral and oxidized products: homoacetate production. Proc. Natl. Acad. Sci. USA 100:825-832, 2003.
46. Mironov, V.N., A.S. Kraev, M.L. Chikindas, B.K. Chernov, A.I. Stepanov, K.G. Skriabin. Functional organization of the riboflavin biosynthesis operon from Bacillus subtilis SHgw. Mol. Gen. Genet. 242:201-208, 1994.
47. Perkins, J.B., A. Sloma, T. Hermann, K. Theriault, E. Zachgo, T. Erdenberger, N. Hannett, N.P. Chatterjee, V. Williams, G.A. Rufo, R. Hatch, J. Pero. Genetic engineering of Bacillus subtilis for the commercial production of riboflavin. J. Ind. Microbiol. Biotechnol. 22:8-18, 1999.
48. Humbelin, M., V. Griesser, T. Keller, W. Schurter, M. Haiker, H.-P. Hohmann, H. Ritz, G. Richter, A. Bacher, A.P.G.M. van Loon. GTP cyclohydrolase II and 3,4-dihydroxy-2-butanone 4-phosphate synthase are the rate-limiting enzymes in riboflavin synthesis of an industrial Bacillus subtilis strain used for riboflavin production. J. Ind. Microbiol. Biotechnol. 22:1-7, 1999.
49. Sauer, U., V. Hatzimankatis, H.P. Hohmann, M. Manneberg, A.P.G.M. van Loon, J.E. Bailey. Physiology and metabolic fluxes of the wild-type and riboflavin-producing Bacillus subtilis. Appl. Environ. Microbiol. 62:3687-3696, 1996.
50. Hugenholtz, J., W. Sybesma, M.N. Groot, W. Wisselink, V. Ladero, K. Burgess, D. van Sinderen, J. Piard, G. Eggink, E.J. Smid, G. Savoy, F. Sesma, T. Jansen, P. Hols, M. Kleerebezem. Metabolic engineering of lactic acid bacteria for the production of nutraceuticals. Antonie van Leeuwenhoek 82:217-235, 2002.
51. Saito, Y., Y. Ishii, H. Hayashi, Y. Imao, T. Akashi, K. Yoshikawa, Y. Noguchi, S. Soeda, M. Yoshida, M. Niwa, J. Hosoda, K. Shimomura. Cloning of genes coding for L-sorbose and L-sorbosone dehydrogenases from Gluconobacter oxydans and microbial production of 2-keto-L-gulonate, a precursor of L-ascorbic acid, in a recombinant G. oxydans strain. Appl. Environ. Microbiol. 63:454-460, 1997.
52. Anderson, S., C.B. Marks, R. Lazarus, J. Miller, S. Stafford, J. Seymour, D. Light, W. Rastetter, D. Estell. Production of 2-keto-L-gulonate, an intermediate in L-Ascorbate synthesis by a genetically modified Erwinia herbicola. Science 230:144-149, 1985.
53. Chotani, G., T. Dodge, A. Hsu, M. Kumar, R. LaDuca, D. Trimbur, W. Weyler, K. Sanford. The commercial production of chemicals using pathway engineering. Biochim. Biophys. Acta 154:3434-455, 2000.
54. Jolly, J., J.F.V. Sebastien, P. Duboc, J.-R. Neeser. Exploiting exopolysaccharides from lactic acid bacteria. Antonie van Leeuwenhoek 82:367-374, 2002.
55. Germond, J.E., M. Delley, N. D'Amico, S.J. Vincent. Heterologous expression and characterization of the exopolysaccharide from Streptococcus thermophilus Sfi39. Eur. J. Biochem. 268:5149-56, 2001.
56. Stingele, F., J.R. Neeser, B. Mollet. Identification and characterization of the eps (exopolysaccharide) gene cluster from Streptococcus thermophilus Sfi6. J. Bacteriol. 178:1680-90, 1996.
57. van Kranenburg, R., I.C. Boels, M. Kleerebezem, W.M. de Vos. Genetics and engineering of microbial exopolysaccharides for food: approaches for the production of existing and novel polysaccharides. Curr. Opin. Biotechnol. 10:498-504, 1999.
58. Looijesteijn, P.J., I.C. Boels, M. Kleerebezem, J. Hugenholtz. Regulation of exopolysaccharide production by Lactococcus lactis subsp. cremoris by the sugar source. Appl. Environ. Microbiol. 65:5003-5008, 1999.
59. Boels, I.C., R. van Kranenburg, J. Hugenholtz, M. Kleerebezem, W.M. de Vos. Sugar catabolism and its impact on the biosynthesis and engineering of exopolysaccharide production in lactic acid bacteria. Int. Dairy J. 11:723-732, 2001.
60. O'Sullivan, L., R.P. Ross, C. Hill. Potential of bacteriocin-producing lactic acid bacteria for improvements in food safety and quality. Biochimie 84:593-604, 2002.
61. Rodriguez, J.M., M.I. Martinez, N. Horn, H.M. Dodd. Heterologous production of bacteriocins by lactic acid bacteria. Int. J. Food Microbiol. 80:101-116, 2002.
62. Martinez, J.M., J. Kok, J.W. Sanders, P.E. Hernandez. Heterologous coproduction of Enterocin A and Pediocin PA-1 by Lactococcus lactis: detection by specific peptide-directed antibodies. Appl. Environ. Microbiol. 66:3543-3549, 2000.
63. Horn, N., M.I. Martinez, J.M. Martinez, P.E. Hernandez, M.J. Gasson, J.M. Rodriguez, H. Dodd. Enhanced production of pediocin PA-1 and coproduction of nisin and pediocin PA-1 by Lactococcus lactis. Appl. Environ. Microbiol. 65:4443-1450, 1999.
64. Horn, N., M.I. Martinez, J.M. Martinez, P.E. Hernandez, M.J. Gasson, J.M. Rodriguez, H. Dodd. Production of pediocin PA-1 by Lactococcus lactis using the lactococcin A secretory apparatus. Appl. Environ. Microbiol. 64:818-823, 1998.
65. Gonzalez, R., B.A. Andrews, J. Molitor, J.A. Asenjo. Metabolic analysis of the synthesis of high levels of intracellular human SOD in S. cerevisiae rhSOD 2060 411 SGA122. Biotechnol. Bioeng. 82:152-169, 2003.
66. Hugenholtz, J., E.J. Smid. Nutraceutical production with food-grade microorganisms. Curr. Opin. Biotechnol. 13:497-507, 2002.
67. Hugenholtz, J., M. Kleerebezem, M. Starrenburg, J. Delcour, W. de Vos, P. Hols. Lactococcus lactis as a cell factory for high-level diacetyl production. Appl. Environ. Microbiol. 66:4112-U14, 2000.
68. Rijnen, L., P. Courtin, J.C. Gripon, M. Yvon. Expression of a heterologous glutamate dehydrogenase gene in Lactococcus lactis highly improves the conversion of amino acids to aroma compounds. Appl. Environ. Microbiol. 66:1354-1359, 2000.
69. Silvestroni, A., C. Connes, F. Sesma, G.S. De Giori, J.C. Piard. Characterization of the melA locus for alpha-galactosidase in Lactobacillus plantarum. Appl. Environ. Microbiol. 68:5464-5471, 2002.
70. Rhodius, V., T.K. Van Dyk, C. Gross, R.A. LaRossa. Impact of genomic technologies on studies of bacterial gene expression. Ann. Rev. Microbiol. 56: 599-624, 2002.
71. Tao, H., R. Gonzalez, A. Martinez, M. Rodriguez, L.O. Ingram, J.F. Preston, K.T. Shanmugam. Engineering a homo-ethanol pathway in Escherichia coli: increased glycolytic flux and levels of expression of glycolytic genes during xylose fermentation. J. Bacteriol. 183:2979-2988, 2001.
72. Gonzalez, R., H. Tao, S.W. York, K.T. Shanmugam, L.O. Ingram. Global gene expression differences associated with changes in glycolytic flux and growth rate in Escherichia coli during the fermentation of glucose and xylose. Biotechnol. Prog. 18:6-20, 2002.
73. Gonzalez, R., H. Tao, J.E. Purvis, S.W. York, K.T. Shanmugam, L.O. Ingram. Gene array-based identification of changes that contribute to ethanol tolerance in ethanologenic Escherichia coli: comparison of KO11 (parent) to LY01 (resistant mutant). Biotechnol. Prog. 19:612-623, 2003.
74. Dharmadi, Y., R. Gonzalez DNA Microarrays: experimental issues, data analysis, and application to bacterial systems. Biotechnol. Prog. 20:1309-1324, 2004.