-
1
-
-
85008071016
-
Studies on absorption of eutectic mixture. I. A comparison of the behavior of eutectic mixture of sulfathiazole and that of ordinary sulfathiazole in man
-
Sekiguchi, K. and N. Obi. 1961. Studies on absorption of eutectic mixture. I. A comparison of the behavior of eutectic mixture of sulfathiazole and that of ordinary sulfathiazole in man. Chem Pharm Bull 9:866-872.
-
(1961)
Chem Pharm Bull
, vol.9
, pp. 866-872
-
-
Sekiguchi, K.1
Obi, N.2
-
2
-
-
0001368366
-
Studies on absorption of eutectic mixture. II. Absorption of fused conglomerates of chloramphenicol and urea in rabbits
-
Sekiguchi, K., N. Obi, and Y. Ueda. 1964. Studies on absorption of eutectic mixture. II. Absorption of fused conglomerates of chloramphenicol and urea in rabbits. Chem Pharm Bull 12:134-144.
-
(1964)
Chem Pharm Bull
, vol.12
, pp. 134-144
-
-
Sekiguchi, K.1
Obi, N.2
Ueda, Y.3
-
3
-
-
84984082270
-
Increasing dissolution rates and gastrointestinal absorption of drugs via solid solutions and eutectic mixtures. II. Experimental evaluation of eutectic mixture: Urea-acetaminophen system
-
Goldberg, A. H., M. Gibaldi, and J. L. Kanig. 1966. Increasing dissolution rates and gastrointestinal absorption of drugs via solid solutions and eutectic mixtures. II. Experimental evaluation of eutectic mixture: Urea-acetaminophen system. J Pharm Sci 55:482-487.
-
(1966)
J Pharm Sci
, vol.55
, pp. 482-487
-
-
Goldberg, A.H.1
Gibaldi, M.2
Kanig, J.L.3
-
4
-
-
84984085031
-
Increasing dissolution rates and gastrointestinal absorption of drugs via solid solutions and eutectic mixtures. III. Experimental evaluation of griseofulvin-succinic acid solution
-
Goldberg, A. H., M. Gibaldi, and J. L. Kanig. 1966. Increasing dissolution rates and gastrointestinal absorption of drugs via solid solutions and eutectic mixtures. III. Experimental evaluation of griseofulvin-succinic acid solution. J Pharm Sci 55:487-492.
-
(1966)
J Pharm Sci
, vol.55
, pp. 487-492
-
-
Goldberg, A.H.1
Gibaldi, M.2
Kanig, J.L.3
-
5
-
-
0013966747
-
New method of solid dispersion for increasing dissolution rates
-
Mayersohn, M. and M. Gibaldi. 1966. New method of solid dispersion for increasing dissolution rates. J Pharm Sci 55:1323-1324.
-
(1966)
J Pharm Sci
, vol.55
, pp. 1323-1324
-
-
Mayersohn, M.1
Gibaldi, M.2
-
6
-
-
0014628768
-
Preparation and dissolution characteristics of several fast-release solid dispersions of griseofulvin
-
Chiou, W. L. and S. Riegelman. 1969. Preparation and dissolution characteristics of several fast-release solid dispersions of griseofulvin. J Pharm Sci 58:1505-1509.
-
(1969)
J Pharm Sci
, vol.58
, pp. 1505-1509
-
-
Chiou, W.L.1
Riegelman, S.2
-
7
-
-
0015124656
-
Pharmaceutical application of solid dispersion systems
-
Chiou, W. L. and S. Riegelman. 1971. Pharmaceutical application of solid dispersion systems. J Pharm Sci 60:1281-1302.
-
(1971)
J Pharm Sci
, vol.60
, pp. 1281-1302
-
-
Chiou, W.L.1
Riegelman, S.2
-
8
-
-
0032885450
-
Solid dispersion of poorly water-soluble drugs: Early promises, subsequent problems, and recent breakthroughs
-
Serajuddin, A. T. M. 1999. Solid dispersion of poorly water-soluble drugs: Early promises, subsequent problems, and recent breakthroughs. J Pharm Sci 88:1058-1066.
-
(1999)
J Pharm Sci
, vol.88
, pp. 1058-1066
-
-
Serajuddin, A.T.M.1
-
9
-
-
0034601240
-
Improving drug solubility for oral delivery using solid dispersions
-
Leuner, C. and J. Dressman. 2000. Improving drug solubility for oral delivery using solid dispersions. Eur J Pharm Biopharm 50:47-60.
-
(2000)
Eur J Pharm Biopharm
, vol.50
, pp. 47-60
-
-
Leuner, C.1
Dressman, J.2
-
10
-
-
85031271393
-
Integrated Drug Product Development-From Lead Candidate Selection to Life-Cycle Management
-
eds. C. G. Smith, and J. T. O'Donnell, 2nd ed. New York: Informa Healthcare
-
Pudipeddi, M., A. T. M. Serajuddin, and D. Mufson. 2006. Integrated Drug Product Development-From Lead Candidate Selection to Life-Cycle Management. In The Process of New Drug Discovery and Development, eds. C. G. Smith, and J. T. O'Donnell, 2nd ed. 15-51. New York: Informa Healthcare.
-
(2006)
The Process of New Drug Discovery and Development
, pp. 15-51
-
-
Pudipeddi, M.1
Serajuddin, A.T.M.2
Mufson, D.3
-
11
-
-
0025944198
-
Relative lipophilicities, solubilities and structure-pharmacological considerations of HMG-CoA reductase inhibitors pravastatin, mevastatin, lovastatin and simvastatin
-
Serajuddin, A. T. M., S. Ranadive, and E. M. Mahoney. 1991. Relative lipophilicities, solubilities and structure-pharmacological considerations of HMG-CoA reductase inhibitors pravastatin, mevastatin, lovastatin and simvastatin. J Pharm Sci 80:830-834.
-
(1991)
J Pharm Sci
, vol.80
, pp. 830-834
-
-
Serajuddin, A.T.M.1
Ranadive, S.2
Mahoney, E.M.3
-
12
-
-
0022453966
-
Preformulation study of a poorly water-soluble drug, a-pentyl-3-(2-quinolinylmethoxy) benzenemethanol: Selection of base for dosage form design
-
Serajuddin, A. T. M., P. C. Sheen, and M. A. Augustine. 1986. Preformulation study of a poorly water-soluble drug, a-pentyl-3-(2-quinolinylmethoxy) benzenemethanol: Selection of base for dosage form design. J Pharm Sci 75:492-196.
-
(1986)
J Pharm Sci
, vol.75
, pp. 492-196
-
-
Serajuddin, A.T.M.1
Sheen, P.C.2
Augustine, M.A.3
-
13
-
-
1142303337
-
What is the true solubility advantage for amorphous pharmaceuticals?
-
Hancock, B. C. and M. Parks. 2000. What is the true solubility advantage for amorphous pharmaceuticals? Pharm Res 17:397-404.
-
(2000)
Pharm Res
, vol.17
, pp. 397-404
-
-
Hancock, B.C.1
Parks, M.2
-
14
-
-
0022634650
-
Physicochemical characterization of oxyphenbutazone and solid-state stability of its amorphous form under various temperature and humidity conditions
-
Matsuda, Y. and S. Kawaguchi. 1986. Physicochemical characterization of oxyphenbutazone and solid-state stability of its amorphous form under various temperature and humidity conditions. Chem Pharm Bull 34:1289-1298.
-
(1986)
Chem Pharm Bull
, vol.34
, pp. 1289-1298
-
-
Matsuda, Y.1
Kawaguchi, S.2
-
15
-
-
23844499379
-
IV-IVC considerations in the development of immediate-release oral dosage form
-
Li, S., H. He, L. J. Parthiban, H. Yin, and A. T. M. Serajuddin. 2005. IV-IVC considerations in the development of immediate-release oral dosage form. J Pharm Sci 94:1396-1417.
-
(2005)
J Pharm Sci
, vol.94
, pp. 1396-1417
-
-
Li, S.1
He, H.2
Parthiban, L.J.3
Yin, H.4
Serajuddin, A.T.M.5
-
16
-
-
0038768850
-
Influence of physicochemical properties on dissolution of drugs in the gastrointestinal tract
-
Horter, D. and J. B. Dressman. 1997. Influence of physicochemical properties on dissolution of drugs in the gastrointestinal tract. Adv Drug Delivery Rev 25:3-14.
-
(1997)
Adv Drug Delivery Rev
, vol.25
, pp. 3-14
-
-
Horter, D.1
Dressman, J.B.2
-
17
-
-
1942434691
-
Development of clinical dosage forms for a poorly water soluble drug I: Application of polyethylene glycol-polysorbate 80 solid dispersion carrier system
-
Dannenfelser, R. M., H. He, Y. Joshi, S. Bateman, and A. T. M. Serajuddin. 2004. Development of clinical dosage forms for a poorly water soluble drug I: Application of polyethylene glycol-polysorbate 80 solid dispersion carrier system. J Pharm Sci 93:1165-1175.
-
(2004)
J Pharm Sci
, vol.93
, pp. 1165-1175
-
-
Dannenfelser, R.M.1
He, H.2
Joshi, Y.3
Bateman, S.4
Serajuddin, A.T.M.5
-
21
-
-
0031664813
-
Phase behavior of binary and ternary amorphous mixtures containing indomethacin, citric acid, and PVP
-
Liu, Q. and G. Zografi. 1998. Phase behavior of binary and ternary amorphous mixtures containing indomethacin, citric acid, and PVP. Pharm Res 15:1202-1206.
-
(1998)
Pharm Res
, vol.15
, pp. 1202-1206
-
-
Liu, Q.1
Zografi, G.2
-
22
-
-
24944503554
-
Solid state characteristics of ternary solid dispersions composed of PVP VA64, Myrj 52 and itraconazole
-
Wang, X., A. Michoel, and G. Van den Mooter. 2005. Solid state characteristics of ternary solid dispersions composed of PVP VA64, Myrj 52 and itraconazole. Int J Pharm 303:54-61.
-
(2005)
Int J Pharm
, vol.303
, pp. 54-61
-
-
Wang, X.1
Michoel, A.2
Van den Mooter, G.3
-
23
-
-
33645371510
-
Pharmaceutical co-crystals
-
Vishweshwar, R., J. A. Mc. Mahon, J. A. Bis, and M. J. Zaworotko. 2006. Pharmaceutical co-crystals. J Pharm Sci 95:499-514.
-
(2006)
J Pharm Sci
, vol.95
, pp. 499-514
-
-
Vishweshwar, R.1
McMahon, J.A.2
Bis, J.A.3
Zaworotko, M.J.4
-
24
-
-
33646850912
-
Effect of hydrogen bonding interactions on the release mechanism of felodipine from nanodispersions with polyvinylpyrrolidone
-
Karavas, E., G. Ktistis, A. Xenakis, and E. Georgarakis. 2006. Effect of hydrogen bonding interactions on the release mechanism of felodipine from nanodispersions with polyvinylpyrrolidone. Eur J Pharm Biopharm 63:103-114.
-
(2006)
Eur J Pharm Biopharm
, vol.63
, pp. 103-114
-
-
Karavas, E.1
Ktistis, G.2
Xenakis, A.3
Georgarakis, E.4
-
25
-
-
0029056118
-
Inhibition of indomethacin crystallization in poly(vinylpyrrolidone) coprecipitates
-
Yoshioka, M., B. C. Hancock, and G. Zografi. 1995. Inhibition of indomethacin crystallization in poly(vinylpyrrolidone) coprecipitates. J Pharm Sci 84:983-986.
-
(1995)
J Pharm Sci
, vol.84
, pp. 983-986
-
-
Yoshioka, M.1
Hancock, B.C.2
Zografi, G.3
-
26
-
-
0030864431
-
Ampiphilic vehicles improve the oral bioavailability of a poorly soluble HIV protease inhibitor at high doses
-
Aungst, B. J., N. H. Nguyen, N. J. Rogers, S. M. Rowe, M. A. Hussain, S. J. White, and L. Shum, 1977. Ampiphilic vehicles improve the oral bioavailability of a poorly soluble HIV protease inhibitor at high doses. Int J Pharm 156:79-88.
-
(1977)
Int J Pharm
, vol.156
, pp. 79-88
-
-
Aungst, B.J.1
Nguyen, N.H.2
Rogers, N.J.3
Rowe, S.M.4
Hussain, M.A.5
White, S.J.6
Shum, L.7
-
27
-
-
33644881395
-
Stabilization of solid dispersions of nimodipine and polyethylene glycol 2000
-
Urbanetz, N. 2006. Stabilization of solid dispersions of nimodipine and polyethylene glycol 2000. Eur J Pharm Sci 28:67-76.
-
(2006)
Eur J Pharm Sci
, vol.28
, pp. 67-76
-
-
Urbanetz, N.1
-
28
-
-
0030580116
-
An investigation into the critical surfactant concentration for solid solubility of hydrophobic drug in different polyethylene glycols
-
Wulff, M., M. Alden, and D. Q. M. Craig. 1996. An investigation into the critical surfactant concentration for solid solubility of hydrophobic drug in different polyethylene glycols. Int J Pharm 142:189-198.
-
(1996)
Int J Pharm
, vol.142
, pp. 189-198
-
-
Wulff, M.1
Alden, M.2
Craig, D.Q.M.3
-
29
-
-
0036254606
-
Multi-unit controlled release systems of nifedipine and nifedipine: Pluronic® F-68 solid dispersion
-
Mehta, K. A., M. S. Kislalioglu, W. Phuapradit, W. A. Malik, and N. H. Shah. 2002. Multi-unit controlled release systems of nifedipine and nifedipine: Pluronic® F-68 solid dispersion. Drug Dev Ind Pharm 28:275-285.
-
(2002)
Drug Dev Ind Pharm
, vol.28
, pp. 275-285
-
-
Mehta, K.A.1
Kislalioglu, M.S.2
Phuapradit, W.3
Malik, W.A.4
Shah, N.H.5
-
30
-
-
33750430305
-
Industrially feasible alternative approaches in the manufacture of solid dispersions: A technical report
-
Karanth, H., V. S. Shenoy, and R. P. Murthy. 2006. Industrially feasible alternative approaches in the manufacture of solid dispersions: A technical report. AAPS Pharm Sci Tech 7:87-96.
-
(2006)
AAPS Pharm Sci Tech
, vol.7
, pp. 87-96
-
-
Karanth, H.1
Shenoy, V.S.2
Murthy, R.P.3
-
31
-
-
1842865536
-
Melt extrusion: From process to drug delivery technology
-
Breitenbach, J. 2002. Melt extrusion: From process to drug delivery technology. Eur J Pharm Biopharm 54:107-117.
-
(2002)
Eur J Pharm Biopharm
, vol.54
, pp. 107-117
-
-
Breitenbach, J.1
-
32
-
-
13444260206
-
Hot-melt extrusion technique: Areview
-
Choksi, R. and H. Zia. 2004. Hot-melt extrusion technique: Areview. Iran J Pharm Res 3:107-117.
-
(2004)
Iran J Pharm Res
, vol.3
, pp. 107-117
-
-
Choksi, R.1
Zia, H.2
-
33
-
-
0032771887
-
Confocal Raman spectroscopy: Analytical approach to solid dispersion and mapping of drugs
-
Breitenbach, J., W. Schrof, and J. Neumann. 1999. Confocal Raman spectroscopy: Analytical approach to solid dispersion and mapping of drugs. Pharm Res 16:1109-1113.
-
(1999)
Pharm Res
, vol.16
, pp. 1109-1113
-
-
Breitenbach, J.1
Schrof, W.2
Neumann, J.3
-
34
-
-
12244283119
-
Characterization of solid dispersions of itraconazole and hydroxypropylmethylcellulose prepared by melt extrusion-part I
-
Verreck, G., K. Six, G. Van den Mooter, L. Baert, J. Peeters, and M. E. Brewster. 2003. Characterization of solid dispersions of itraconazole and hydroxypropylmethylcellulose prepared by melt extrusion-part I. Int J Pharm 251:165-174.
-
(2003)
Int J Pharm
, vol.251
, pp. 165-174
-
-
Verreck, G.1
Six, K.2
Van den Mooter, G.3
Baert, L.4
Peeters, J.5
Brewster, M.E.6
-
35
-
-
0035821384
-
Evaluation of a floating dosage form of nicardipine hydrochloride and hydroxypropylmethylcellulose acetate succinate prepared using a twin-screw extruder
-
Nakamichi, K., H. Yasuura, H. Fukui, M. Oka, and S. Izumi. 2001. Evaluation of a floating dosage form of nicardipine hydrochloride and hydroxypropylmethylcellulose acetate succinate prepared using a twin-screw extruder. Int J Pharm 218:103-112.
-
(2001)
Int J Pharm
, vol.218
, pp. 103-112
-
-
Nakamichi, K.1
Yasuura, H.2
Fukui, H.3
Oka, M.4
Izumi, S.5
-
36
-
-
33748514818
-
Characterization of poly(ethyleneoxide) as a drug carrier in hot-melt extrusion
-
Li, L., O. Abu Baker, and Z. J. Shao. 2006. Characterization of poly(ethyleneoxide) as a drug carrier in hot-melt extrusion. Drug Dev Ind Pharm 32:991-1002.
-
(2006)
Drug Dev Ind Pharm
, vol.32
, pp. 991-1002
-
-
Li, L.1
Abu Baker, O.2
Shao, Z.J.3
-
37
-
-
0035095847
-
Characterization of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers
-
Forster, A., J. Hempenstall, and T. Rades. 2001. Characterization of glass solutions of poorly water-soluble drugs produced by melt extrusion with hydrophilic amorphous polymers. J Pharm Pharmacol 53:303-315.
-
(2001)
J Pharm Pharmacol
, vol.53
, pp. 303-315
-
-
Forster, A.1
Hempenstall, J.2
Rades, T.3
-
38
-
-
0342804284
-
Melt extrusion-an alternative method for enhancing the dissolution rate of 17-estradiol hemihydrate
-
Hulsmann, S., T. Backensfeld, S. Keitel, and R. Bodmeier. 2000. Melt extrusion-an alternative method for enhancing the dissolution rate of 17-estradiol hemihydrate. Eur J Pharm Biopharm 49:237-242.
-
(2000)
Eur J Pharm Biopharm
, vol.49
, pp. 237-242
-
-
Hulsmann, S.1
Backensfeld, T.2
Keitel, S.3
Bodmeier, R.4
-
39
-
-
30544436192
-
Characterization of physico-mechanical properties of indomethacin and polymers to assess their suitability for hot-melt extrusion process as a means to manufacture solid dispersion/solution
-
Chokshi, R. J., H. K. Sandhu, R. M. Iyer, N. H. Shah, A. W. Malick, and H. Zia. 2005. Characterization of physico-mechanical properties of indomethacin and polymers to assess their suitability for hot-melt extrusion process as a means to manufacture solid dispersion/solution. J Pharm Sci 94:2463-2474.
-
(2005)
J Pharm Sci
, vol.94
, pp. 2463-2474
-
-
Chokshi, R.J.1
Sandhu, H.K.2
Iyer, R.M.3
Shah, N.H.4
Malick, A.W.5
Zia, H.6
-
40
-
-
0038493711
-
Itraconazole formulation studies of the melt extrusion process with mixture design
-
Rambali, B., G. Verreck, L. Baert, and D. L. Massart. 2003. Itraconazole formulation studies of the melt extrusion process with mixture design. Drug Dev Ind Pharm 29:641-652.
-
(2003)
Drug Dev Ind Pharm
, vol.29
, pp. 641-652
-
-
Rambali, B.1
Verreck, G.2
Baert, L.3
Massart, D.L.4
-
41
-
-
19944432124
-
Clinical study of solid dispersions of itraconazole prepared by hot-stage extrusion
-
Six, K., T. Daems, J. D. Hoon, A. V. Hecken, M. Depre, M. P. Bouche, P. Prinsen, G. Verreck, J. Peeters, M. E. Brewster, and G. Van den Mooter. 2005. Clinical study of solid dispersions of itraconazole prepared by hot-stage extrusion. Eur J Pharm Sci 24:179-186.
-
(2005)
Eur J Pharm Sci
, vol.24
, pp. 179-186
-
-
Six, K.1
Daems, T.2
Hoon, J.D.3
Hecken, A.V.4
Depre, M.5
Bouche, M.P.6
Prinsen, P.7
Verreck, G.8
Peeters, J.9
Brewster, M.E.10
Van den Mooter, G.11
-
42
-
-
33750891308
-
Filling of liquids and semi-solids into hard two-piece capsules
-
eds. F. Podczeck, and B. E. Jones, 2nd ed. Bath: The Batch Press
-
Rowley, G. 2004. Filling of liquids and semi-solids into hard two-piece capsules. In Pharmaceutical Capsules, eds. F. Podczeck, and B. E. Jones, 2nd ed. 169-194. Bath: The Batch Press.
-
(2004)
Pharmaceutical Capsules
, pp. 169-194
-
-
Rowley, G.1
-
43
-
-
84940280122
-
Physical characterization and scale-up manufacture of Gelucire 50/13 based capsule formulations
-
Robinson, L. 2001. Physical characterization and scale-up manufacture of Gelucire 50/13 based capsule formulations. Bulletin Technique Gattefosse 97:97-111.
-
(2001)
Bulletin Technique Gattefosse
, vol.97
, pp. 97-111
-
-
Robinson, L.1
-
44
-
-
21244445440
-
Spray-dried amorphous solid dispersions of simvastatin, a low Tg drug: In vitro and in vivo evaluations
-
Ambike, A. A., K. R. Mahadik, and A. Paradkar. 2005. Spray-dried amorphous solid dispersions of simvastatin, a low Tg drug: In vitro and in vivo evaluations. Pharm Res 22:990-998.
-
(2005)
Pharm Res
, vol.22
, pp. 990-998
-
-
Ambike, A.A.1
Mahadik, K.R.2
Paradkar, A.3
-
45
-
-
0141997759
-
Solid dispersions: Revival with greater possibilities and applications in oral drug delivery
-
Sethia, S. and E. Squillante. 2003. Solid dispersions: Revival with greater possibilities and applications in oral drug delivery. Crit Rev Ther Drug Carrier Syst 20:215-247.
-
(2003)
Crit Rev Ther Drug Carrier Syst
, vol.20
, pp. 215-247
-
-
Sethia, S.1
Squillante, E.2
-
46
-
-
0037381525
-
Droplet and particle size relationship and shell thickness of inhalable lactose particles during spray drying
-
Elversson, J., A. Millqvist-Fureby, G. Alderborn, and U. Elofsson. 2003. Droplet and particle size relationship and shell thickness of inhalable lactose particles during spray drying. J Pharm Sci 92:900-910.
-
(2003)
J Pharm Sci
, vol.92
, pp. 900-910
-
-
Elversson, J.1
Millqvist-Fureby, A.2
Alderborn, G.3
Elofsson, U.4
-
47
-
-
0034964315
-
Particle design using supercritical fluids: Literature and patent survey
-
Jung, J. and M. Perrut. 2001. Particle design using supercritical fluids: Literature and patent survey. J Supercrit Fluids 20:179-219.
-
(2001)
J Supercrit Fluids
, vol.20
, pp. 179-219
-
-
Jung, J.1
Perrut, M.2
-
48
-
-
0030791709
-
Pharmaceutical processing with supercritical carbon dioxide
-
Subramanian, B., R. A. Rajewski, and K. Snavely. 1997. Pharmaceutical processing with supercritical carbon dioxide. J Pharm Sci 86:885-890.
-
(1997)
J Pharm Sci
, vol.86
, pp. 885-890
-
-
Subramanian, B.1
Rajewski, R.A.2
Snavely, K.3
-
49
-
-
0032771526
-
Phase behavioral effects on particle formation process using supercritical fluids
-
Palakodaty, S. and P. York. 1999. Phase behavioral effects on particle formation process using supercritical fluids. Pharm Res 16:976-985.
-
(1999)
Pharm Res
, vol.16
, pp. 976-985
-
-
Palakodaty, S.1
York, P.2
-
50
-
-
33144459437
-
Formation and characterization of porous indomethacin-PVP coprecipitates prepared using solvent-free supercritical fluid processing
-
Gong, K., R. Viboonkiat, I. U. Rehman, G. Buckton, and J. A. Darr. 2005. Formation and characterization of porous indomethacin-PVP coprecipitates prepared using solvent-free supercritical fluid processing. J Pharm Sci 2583-2590.
-
(2005)
J Pharm Sci
, pp. 2583-2590
-
-
Gong, K.1
Viboonkiat, R.2
Rehman, I.U.3
Buckton, G.4
Darr, J.A.5
-
51
-
-
0036771080
-
Physicochemical characterization of solid dispersions of carbamazepine formulated by supercritical carbon dioxide and conventional solvent evaporation method
-
Sethia, S. and E. Squillante. 2002. Physicochemical characterization of solid dispersions of carbamazepine formulated by supercritical carbon dioxide and conventional solvent evaporation method. J Pharm Sci 91:1948-1957.
-
(2002)
J Pharm Sci
, vol.91
, pp. 1948-1957
-
-
Sethia, S.1
Squillante, E.2
-
52
-
-
0036858167
-
Micronization of pharmaceutical substances by rapid expansion of supercritical solutions (RESS): Experiments and modeling
-
Türk, M., B. Helfgen, P. Hils, R. Lietzow, and K. Schaber. 2002. Micronization of pharmaceutical substances by rapid expansion of supercritical solutions (RESS): Experiments and modeling. Particle & Particle Systems Characterization 19:327-335.
-
(2002)
Particle & Particle Systems Characterization
, vol.19
, pp. 327-335
-
-
Türk, M.1
Helfgen, B.2
Hils, P.3
Lietzow, R.4
Schaber, K.5
-
53
-
-
23144436640
-
Crystal doping aided by rapid expansion of supercritical solutions
-
Vemavarapu, C., M. J. Mollan, and T. E. Needham. 2002. Crystal doping aided by rapid expansion of supercritical solutions. AAPS Pharm Sci Tech 3:1-15.
-
(2002)
AAPS Pharm Sci Tech
, vol.3
, pp. 1-15
-
-
Vemavarapu, C.1
Mollan, M.J.2
Needham, T.E.3
-
54
-
-
0027623460
-
Solubility of naproxen in supercritical carbon dioxide with and without cosolvents
-
Ting, S. S. T., S. J. Macnaughtn, D. L. Tomasko, and N. R. Foster. 1993. Solubility of naproxen in supercritical carbon dioxide with and without cosolvents. Ind Eng Chem Res 32:1471-1481.
-
(1993)
Ind Eng Chem Res
, vol.32
, pp. 1471-1481
-
-
Ting, S.S.T.1
Macnaughtn, S.J.2
Tomasko, D.L.3
Foster, N.R.4
-
56
-
-
0344305532
-
Processing pharmaceutical compounds using dense gas technology
-
Foster, N., R. Mammucari, F. Dehghani, A. Barrett, K. Bezanehtak, E. Coen, G. Combes, L. Meure, A. Ng, H. L. Regtop, and A. Tandya. 2003. Processing pharmaceutical compounds using dense gas technology. Ind Eng Chem Pres 42:6476-6493.
-
(2003)
Ind Eng Chem Pres
, vol.42
, pp. 6476-6493
-
-
Foster, N.1
Mammucari, R.2
Dehghani, F.3
Barrett, A.4
Bezanehtak, K.5
Coen, E.6
Combes, G.7
Meure, L.8
Ng, A.9
Regtop, H.L.10
Tandya, A.11
-
57
-
-
23944480400
-
Improved physicochemical characteristics of felodipine solid dispersion particles by supercritical anti-solvent precipitation process
-
Won, D. H., M. S. Kim, S. Lee, J. S. Park, and S. J. Hwang. 2005. Improved physicochemical characteristics of felodipine solid dispersion particles by supercritical anti-solvent precipitation process. Int J Pharm 301:199-208.
-
(2005)
Int J Pharm
, vol.301
, pp. 199-208
-
-
Won, D.H.1
Kim, M.S.2
Lee, S.3
Park, J.S.4
Hwang, S.J.5
-
58
-
-
14344257829
-
Dense gas antisolvent precipitation: A comparative investigation of the GAS and PCA techniques
-
Fusaro, F., M., M. Hanchen, M. Mazzotti, G. Muhrer, and B. Subramaniam. 2005. Dense gas antisolvent precipitation: A comparative investigation of the GAS and PCA techniques. Ind Eng Chem Res 44:1502-1509.
-
(2005)
Ind Eng Chem Res
, vol.44
, pp. 1502-1509
-
-
Fusaro, F.M.1
Hanchen, M.2
Mazzotti, M.3
Muhrer, G.4
Subramaniam, B.5
-
59
-
-
30744456780
-
Use of compressed gas precipitation to enhance the dissolution behavior of a poorly water-soluble drug: Generation of drug microparticles and drug-polymer solid dispersions
-
Muhrer, G., U. Meier, F. Fusaro, S. Albano, and M. Mazzotti. 2006. Use of compressed gas precipitation to enhance the dissolution behavior of a poorly water-soluble drug: Generation of drug microparticles and drug-polymer solid dispersions. Int J Pham 308:69-83.
-
(2006)
Int J Pham
, vol.308
, pp. 69-83
-
-
Muhrer, G.1
Meier, U.2
Fusaro, F.3
Albano, S.4
Mazzotti, M.5
-
60
-
-
33144463572
-
Supercritical fluid crystallization of griseofulvin: Crystal habit modification with a selective growth inhibitor
-
Jarmer, D. J., C. S. Lengsfeld, K. S. Anseth, and T. W. Randolph. 2005. Supercritical fluid crystallization of griseofulvin: Crystal habit modification with a selective growth inhibitor. J Pharm Sci 94:2688-2702.
-
(2005)
J Pharm Sci
, vol.94
, pp. 2688-2702
-
-
Jarmer, D.J.1
Lengsfeld, C.S.2
Anseth, K.S.3
Randolph, T.W.4
-
61
-
-
0034882323
-
Crystallization of pure anhydrous polymorphs of carbamezapine by solution enhanced dispersion with supercritical fluids (SEDS)
-
Edwards, A. D., B. Y. Shekunov, A. Kordikowski, R. T. Forbes, and P. York. 2001. Crystallization of pure anhydrous polymorphs of carbamezapine by solution enhanced dispersion with supercritical fluids (SEDS). J Pharm Sci 90:1115-1124.
-
(2001)
J Pharm Sci
, vol.90
, pp. 1115-1124
-
-
Edwards, A.D.1
Shekunov, B.Y.2
Kordikowski, A.3
Forbes, R.T.4
York, P.5
-
63
-
-
0024218073
-
Effect of vehicle amphiphilicity on the dissolution and bioavailability of a poorly water-soluble drugs from solid dispersions
-
Serajuddin, A. T. M., P. C. Sheen, D. Mufson. D. F. Bernstein, and M. A. Augustine. 1988. Effect of vehicle amphiphilicity on the dissolution and bioavailability of a poorly water-soluble drugs from solid dispersions. J Pharm Sci 77:414-417.
-
(1988)
J Pharm Sci
, vol.77
, pp. 414-417
-
-
Serajuddin, A.T.M.1
Sheen, P.C.2
Mufson, D.3
Bernstein, D.F.4
Augustine, M.A.5
-
64
-
-
85123271521
-
-
Paper presented at the AAPS Annual Meeting, Boston, November 2-6, 1997
-
Al-Razzak, L. A., L. Dias, D. Kaul, and S. Ghosh. 1997. Lipid based systems for oral delivery: Physiological mechanistic and product development perspectives. Paper presented at the AAPS Annual Meeting, Boston, November 2-6, 1997.
-
(1997)
Lipid based systems for oral delivery: Physiological mechanistic and product development perspectives
-
-
Al-Razzak, L.A.1
Dias, L.2
Kaul, D.3
Ghosh, S.4
-
65
-
-
0042156881
-
An investigation into the structure and bioavailability of A-tocopherol dispersions in Gelucire 44/14
-
Barker, S. A., S. P. Yap, K. H. Yuen, C. P. McCoy, J. R. Murphy, and D. Q. M. Craig. 2003. An investigation into the structure and bioavailability of A-tocopherol dispersions in Gelucire 44/14. J Controlled Release 91:477-488.
-
(2003)
J Controlled Release
, vol.91
, pp. 477-488
-
-
Barker, S.A.1
Yap, S.P.2
Yuen, K.H.3
McCoy, C.P.4
Murphy, J.R.5
Craig, D.Q.M.6
-
66
-
-
0037006882
-
Solid-state characterization of nifedipine solid dispersions
-
Vippagunta, S. R., K. A. Maul, S. Tallavajhala, and D. J. W. Grant. 2002. Solid-state characterization of nifedipine solid dispersions. Int J Pharm 236:111-123.
-
(2002)
Int J Pharm
, vol.236
, pp. 111-123
-
-
Vippagunta, S.R.1
Maul, K.A.2
Tallavajhala, S.3
Grant, D.J.W.4
-
67
-
-
23144432892
-
Oral formulation of a novel antiviral agent, PG301029, in a mixture of Gelucire 44/14 and DMA (2:1, wt/wt)
-
He, Y., J. L. H. Johnson, and S. H. Yalkowsky. 2005. Oral formulation of a novel antiviral agent, PG301029, in a mixture of Gelucire 44/14 and DMA (2:1, wt/wt). AAPS PharmSci Tech 6:1-5.
-
(2005)
AAPS PharmSci Tech
, vol.6
, pp. 1-5
-
-
He, Y.1
Johnson, J.L.H.2
Yalkowsky, S.H.3
-
68
-
-
17644421075
-
Preparation and in vitro characterization of a semi solid dispersion of flurbiprofen with Gelucire 44/14 and Labrasol
-
Soliman, M. S. and M. A. Khan. 2005. Preparation and in vitro characterization of a semi solid dispersion of flurbiprofen with Gelucire 44/14 and Labrasol. Pharmazie 60:288-293.
-
(2005)
Pharmazie
, vol.60
, pp. 288-293
-
-
Soliman, M.S.1
Khan, M.A.2
-
69
-
-
85123268699
-
Enhanced bioavailability of piroxicam using Gelucire 44/14 and Labrasol: In vitro and in vivo evaluation
-
Nilufer, Y., K. Aysegul, O. Yalcin, S. Ayhan, A. O. Sibel, and B. Tamer. 2003. Enhanced bioavailability of piroxicam using Gelucire 44/14 and Labrasol: In vitro and in vivo evaluation. Eur J Pharm Biopharm 235:247-265.
-
(2003)
Eur J Pharm Biopharm
, vol.235
, pp. 247-265
-
-
Nilufer, Y.1
Aysegul, K.2
Yalcin, O.3
Ayhan, S.4
Sibel, A.O.5
Tamer, B.6
-
70
-
-
0025269652
-
Improved dissolution of a poorly water-soluble drug from solid dispersions in poly(ethylene glycol)-polysorbate 80 mixtures
-
Serajuddin, A. T. M., P. C. Sheen PC, and M. A. Augustine. 1990. Improved dissolution of a poorly water-soluble drug from solid dispersions in poly(ethylene glycol)-polysorbate 80 mixtures. J Pharm Sci 79:463-464.
-
(1990)
J Pharm Sci
, vol.79
, pp. 463-464
-
-
Serajuddin, A.T.M.1
Sheen, P.C.2
Augustine, M.A.3
-
71
-
-
0027054357
-
Structural properties of poly(ethylene glycol)-polysorbate 80 mixture, a solid dispersion vehicle
-
Morris, K. R., G. T. Knipp, and A. T. M. Serajuddin. 1992. Structural properties of poly(ethylene glycol)-polysorbate 80 mixture, a solid dispersion vehicle. J Pharm Sci 81:1185-1188.
-
(1992)
J Pharm Sci
, vol.81
, pp. 1185-1188
-
-
Morris, K.R.1
Knipp, G.T.2
Serajuddin, A.T.M.3
-
72
-
-
0346157322
-
Bioavailability enhancement of a poorly water-soluble drug by solid dispersion in polyethylene glycol-polysorbate 80 mixture
-
Joshi, H. N., R. W. Tejwani, M. Davidovich, V. P. Sahasrabudhe, M. Jemal, M. S. Bathala, S. A. Varia, and A. T. M. Serajuddin. 2004. Bioavailability enhancement of a poorly water-soluble drug by solid dispersion in polyethylene glycol-polysorbate 80 mixture. Int J Pharm 269:251-258.
-
(2004)
Int J Pharm
, vol.269
, pp. 251-258
-
-
Joshi, H.N.1
Tejwani, R.W.2
Davidovich, M.3
Sahasrabudhe, V.P.4
Jemal, M.5
Bathala, M.S.6
Varia, S.A.7
Serajuddin, A.T.M.8
-
73
-
-
0027311037
-
Dissolution behavior of drugs from binary and ternary systems
-
Veiga, M. D., C. Escobar, and M. J. Bernard. 1993. Dissolution behavior of drugs from binary and ternary systems. Int J Pharm 93:215-220.
-
(1993)
Int J Pharm
, vol.93
, pp. 215-220
-
-
Veiga, M.D.1
Escobar, C.2
Bernard, M.J.3
-
74
-
-
0028956464
-
Formulation studies of a poorly water-soluble drug in solid dispersions to improve bioavailability
-
Sheen, P. C., V. K. Khetarpal, C. M. Cariola, and C. E. Rowlings. Formulation studies of a poorly water-soluble drug in solid dispersions to improve bioavailability. Int J Pharm 18:221-227.
-
Int J Pharm
, vol.18
, pp. 221-227
-
-
Sheen, P.C.1
Khetarpal, V.K.2
Cariola, C.M.3
Rowlings, C.E.4
-
75
-
-
0033427847
-
Vitamin-E TPGS increases absorption flux of an HIV protease inhibitor by enhancing its solubility and permeability
-
Yu, L., A. Bridgers, J. Polli, A. Vickers, S. Long, A. Roy, R. Winnike, and M. Coffin. 1999. Vitamin-E TPGS increases absorption flux of an HIV protease inhibitor by enhancing its solubility and permeability. Pharm Res 16:1812-1817.
-
(1999)
Pharm Res
, vol.16
, pp. 1812-1817
-
-
Yu, L.1
Bridgers, A.2
Polli, J.3
Vickers, A.4
Long, S.5
Roy, A.6
Winnike, R.7
Coffin, M.8
-
76
-
-
0034665061
-
The formulation of halofantrine as either non-solubilising PEG6000 or solubilising lipid based solid dispersion: Physical stability and absolute bioavailability assessment
-
Khoo, S. M., C. J. H. Porter, and W. N. Charman. 2000. The formulation of halofantrine as either non-solubilising PEG6000 or solubilising lipid based solid dispersion: Physical stability and absolute bioavailability assessment. Int J Pharm 205:65-78.
-
(2000)
Int J Pharm
, vol.205
, pp. 65-78
-
-
Khoo, S.M.1
Porter, C.J.H.2
Charman, W.N.3
-
77
-
-
20744447950
-
Enhanced oral paclitaxel absorption with Vitamin E-TPGS: Effect on solubility and permeability in vitro, in situ and in vivo
-
Varma, M. V. and R. Panchagnula. 2005. Enhanced oral paclitaxel absorption with Vitamin E-TPGS: Effect on solubility and permeability in vitro, in situ and in vivo. Eur J Pharm Sci 25:445-453.
-
(2005)
Eur J Pharm Sci
, vol.25
, pp. 445-453
-
-
Varma, M.V.1
Panchagnula, R.2
-
78
-
-
85123269504
-
Vitamin E TPGS as a vehicle for drug delivery system. Paper presented at AAPS short course
-
Parsippany, NJ, June 3, 1998
-
Wu, S. H., 1998. Vitamin E TPGS as a vehicle for drug delivery system. Paper presented at AAPS short course Formulation with Lipids, Parsippany, NJ, June 3, 1998.
-
(1998)
Formulation with Lipids
-
-
Wu, S.H.1
-
79
-
-
0027322329
-
Use of water-soluble liquid Vitamin E to enhance cyclosporine absorption in children after liver transplant
-
Boudreaux, J. P., D. H. Hayes, S. Mizrahi, P. Maggiore, J. Blazek, and D. Dick. 1993. Use of water-soluble liquid Vitamin E to enhance cyclosporine absorption in children after liver transplant. Transplant Proc 25:1875-1881.
-
(1993)
Transplant Proc
, vol.25
, pp. 1875-1881
-
-
Boudreaux, J.P.1
Hayes, D.H.2
Mizrahi, S.3
Maggiore, P.4
Blazek, J.5
Dick, D.6
-
80
-
-
0027164837
-
Multicenter trial of D-a-Tocopheryl Polyethylene Glycol 1000 succinate for treatment of Vitamin E deficiency in children with chronic choleostasis
-
Sokol, R. J., N. Butler-Simon, C. Connor, J. E. Heui, F. R. Sinatra, F. J. Suchy, M. B. Heyman, J. Perrault, R. J. Rothbaum, and J. Levy. 1993. Multicenter trial of D-a-Tocopheryl Polyethylene Glycol 1000 succinate for treatment of Vitamin E deficiency in children with chronic choleostasis, Gastroenterology 104:1727-1735.
-
(1993)
Gastroenterology
, vol.104
, pp. 1727-1735
-
-
Sokol, R.J.1
Butler-Simon, N.2
Connor, C.3
Heui, J.E.4
Sinatra, F.R.5
Suchy, F.J.6
Heyman, M.B.7
Perrault, J.8
Rothbaum, R.J.9
Levy, J.10
-
81
-
-
0029925318
-
The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers
-
Chang, T., L. Z. Benet, and M. F. Hebert. 1996. The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers. Clin Pharmacol Ther 59:297-303.
-
(1996)
Clin Pharmacol Ther
, vol.59
, pp. 297-303
-
-
Chang, T.1
Benet, L.Z.2
Hebert, M.F.3
-
82
-
-
0031395859
-
Physicochemical characterization of piroxicam-poloxamer solid dispersion
-
Shin, S. C. and C. W. Cho. 1997. Physicochemical characterization of piroxicam-poloxamer solid dispersion. Pharm Dev Technol 2:403-407.
-
(1997)
Pharm Dev Technol
, vol.2
, pp. 403-407
-
-
Shin, S.C.1
Cho, C.W.2
-
83
-
-
0034601670
-
Influence of pluronic F-68 on dissolution and biavailability characteristics of multiple-layer pellets of nifedipine for controlled release delivery
-
Ho, H.O., C. N. Chen, and M.T. Sheu. 2000. Influence of pluronic F-68 on dissolution and biavailability characteristics of multiple-layer pellets of nifedipine for controlled release delivery. J Control Release 68:433-440.
-
(2000)
J Control Release
, vol.68
, pp. 433-440
-
-
Ho, H.O.1
Chen, C.N.2
Sheu, M.T.3
-
84
-
-
0036166898
-
Preparation and characterization of ibuprofen-poloxamer 188 granules obtained by melt granulation
-
Passerini, N., B. Albertini, and M. L. Gonzalez-Rodriguez. 2002. Preparation and characterization of ibuprofen-poloxamer 188 granules obtained by melt granulation. Eur J Pharm Sci 15:71-78.
-
(2002)
Eur J Pharm Sci
, vol.15
, pp. 71-78
-
-
Passerini, N.1
Albertini, B.2
Gonzalez-Rodriguez, M.L.3
-
85
-
-
6944243071
-
Enhancing the bioavailability of ABT-963 using solid dispersion containing Pluronic F-68
-
Chen, Y., G. G. Z. Zhang, J. Neilly, K. Marsh, D. Mawhinney, and Y. D. Sanzgiri. 2004. Enhancing the bioavailability of ABT-963 using solid dispersion containing Pluronic F-68. Int J Pharm 286:69-80.
-
(2004)
Int J Pharm
, vol.286
, pp. 69-80
-
-
Chen, Y.1
Zhang, G.G.Z.2
Neilly, J.3
Marsh, K.4
Mawhinney, D.5
Sanzgiri, Y.D.6
-
86
-
-
23844515061
-
Bioavailability enhancement of a COX-2 inhibitor, BMS-347070, from nanocrystalline dispersion prepared by spray-drying
-
Yin, S. X., M. Franchini, J. L. Chen, A. Hsieh, S. Jen, T. Lee, M. Hussain, and R. Smith. 2005. Bioavailability enhancement of a COX-2 inhibitor, BMS-347070, from nanocrystalline dispersion prepared by spray-drying. J Pharm Sci 94:1598-1607.
-
(2005)
J Pharm Sci
, vol.94
, pp. 1598-1607
-
-
Yin, S.X.1
Franchini, M.2
Chen, J.L.3
Hsieh, A.4
Jen, S.5
Lee, T.6
Hussain, M.7
Smith, R.8
-
87
-
-
23144432623
-
Effect of formulation variables on preparation and evaluation of gelled self-emulsifying drug delivery systems (SEDDS) of ketoprofen
-
Patil, P., J. Joshi, and P. Paradkar. 2004. Effect of formulation variables on preparation and evaluation of gelled self-emulsifying drug delivery systems (SEDDS) of ketoprofen. AAPS Pharm Sci Tech 5:1-8.
-
(2004)
AAPS Pharm Sci Tech
, vol.5
, pp. 1-8
-
-
Patil, P.1
Joshi, J.2
Paradkar, P.3
-
88
-
-
0022409189
-
Influence of wetting factors on the dissolution behavior of flufenamic acid
-
Itai, S., M. Nemoto, S. Kouchiwa, H. Murayama, and T. Nagai. 1985. Influence of wetting factors on the dissolution behavior of flufenamic acid. Chem Pharm Bull 33:5464-5473.
-
(1985)
Chem Pharm Bull
, vol.33
, pp. 5464-5473
-
-
Itai, S.1
Nemoto, M.2
Kouchiwa, S.3
Murayama, H.4
Nagai, T.5
-
89
-
-
0014592643
-
Dissolution characteristics of reserpine-polyvinylpyrrolidone co-precipitates
-
Bates, T. R. 1969. Dissolution characteristics of reserpine-polyvinylpyrrolidone co-precipitates. J Pharm Pharmacol 21:710-712.
-
(1969)
J Pharm Pharmacol
, vol.21
, pp. 710-712
-
-
Bates, T.R.1
-
90
-
-
0014515660
-
Dissolution rates of high energy polyvinylpyrrolidone (PVP)-sulfathiazole coprecipitates
-
Simonelli, A. P., S. C. Mehta, and W. I. Higuchi. 1969. Dissolution rates of high energy polyvinylpyrrolidone (PVP)-sulfathiazole coprecipitates. J Pharm Sci 58:538-549.
-
(1969)
J Pharm Sci
, vol.58
, pp. 538-549
-
-
Simonelli, A.P.1
Mehta, S.C.2
Higuchi, W.I.3
-
91
-
-
0032940583
-
Properties of solid dispersions of piroxicam in polyvinylpyrrolidone
-
Tantishaiyakul, V., N. Kaewnopparat, and S. Ingkatawornwong. 1999. Properties of solid dispersions of piroxicam in polyvinylpyrrolidone. Int. J. Pharm 181:143-151.
-
(1999)
Int. J. Pharm
, vol.181
, pp. 143-151
-
-
Tantishaiyakul, V.1
Kaewnopparat, N.2
Ingkatawornwong, S.3
-
92
-
-
0014793002
-
Inhibition of sulfathiazole crystal growth by polyvinylpyrrolidone
-
Simonelli, A. P., S. C. Mehta, and W. I. Higuchi. 1970. Inhibition of sulfathiazole crystal growth by polyvinylpyrrolidone. J Pharm Sci 59:633-638.
-
(1970)
J Pharm Sci
, vol.59
, pp. 633-638
-
-
Simonelli, A.P.1
Mehta, S.C.2
Higuchi, W.I.3
-
93
-
-
0024370870
-
Accelerated stability of an x-ray amorphous furesemide polyvinyl pyrrolidone solid dispersions
-
Doherty, C. and P. York. 1989. Accelerated stability of an x-ray amorphous furesemide polyvinyl pyrrolidone solid dispersions. Drug Dev Ind Pharm 15:1969-1987.
-
(1989)
Drug Dev Ind Pharm
, vol.15
, pp. 1969-1987
-
-
Doherty, C.1
York, P.2
-
94
-
-
0031725929
-
Investigation of formulation approaches to improve the dissolution of SB-210661, a poorly water soluble 5-lipoxygenase inhibitor
-
Perng, C. Y., A. S. Kearney, K. Patel, N. R. Palepu, and G. Zuber. 1998. Investigation of formulation approaches to improve the dissolution of SB-210661, a poorly water soluble 5-lipoxygenase inhibitor. Int J Pharm 176:31-38.
-
(1998)
Int J Pharm
, vol.176
, pp. 31-38
-
-
Perng, C.Y.1
Kearney, A.S.2
Patel, K.3
Palepu, N.R.4
Zuber, G.5
-
95
-
-
0032997934
-
Improving the oral bioavailability of albendazole in rabbits by the solid dispersion technique
-
Kohri, N., Y. Yamayoshi, H. Xin, K. Iseki, N. Sato, S. Todo, and K. Miyazaki. 1999. Improving the oral bioavailability of albendazole in rabbits by the solid dispersion technique. J Pharm Pharmacol 51:159-164.
-
(1999)
J Pharm Pharmacol
, vol.51
, pp. 159-164
-
-
Kohri, N.1
Yamayoshi, Y.2
Xin, H.3
Iseki, K.4
Sato, N.5
Todo, S.6
Miyazaki, K.7
-
96
-
-
0020362293
-
Stability and bioavailability of nifedipine in fine granules
-
Sugimoto, I., K. Sasaki, A. Kuchiki, T. Ishihara, and H. Nakagawa. 1982. Stability and bioavailability of nifedipine in fine granules. Chem Pharm Bull 30:4479-4488.
-
(1982)
Chem Pharm Bull
, vol.30
, pp. 4479-4488
-
-
Sugimoto, I.1
Sasaki, K.2
Kuchiki, A.3
Ishihara, T.4
Nakagawa, H.5
-
97
-
-
0030805738
-
Inhibitory effects of water-soluble polymers on precipitation of RS-8359
-
Usui, F., K. Maeda, A. Kusai, K. Nishimura, and K. Yamamoto. 1991. Inhibitory effects of water-soluble polymers on precipitation of RS-8359. Int J Pharm 154:59-66.
-
(1991)
Int J Pharm
, vol.154
, pp. 59-66
-
-
Usui, F.1
Maeda, K.2
Kusai, A.3
Nishimura, K.4
Yamamoto, K.5
-
98
-
-
85123269948
-
-
2nd Annual Simonelli Conference in Pharmaceutical Sciences, June 9, Long Island University
-
Shanker, R. M. 2005. Current concepts in the science of solid dispersion, 2nd Annual Simonelli Conference in Pharmaceutical Sciences, June 9, Long Island University.
-
(2005)
Current concepts in the science of solid dispersion
-
-
Shanker, R.M.1
-
99
-
-
1242298506
-
Evaluation of hypromellose acetate succinate (HPMC AS) as a carrier in solid dispersions
-
Tanno, F., Y. Nishiyama, H. Kokubo, and S. Obara. 2004. Evaluation of hypromellose acetate succinate (HPMC AS) as a carrier in solid dispersions. Drug Dev Ind Pharm 30:9-17.
-
(2004)
Drug Dev Ind Pharm
, vol.30
, pp. 9-17
-
-
Tanno, F.1
Nishiyama, Y.2
Kokubo, H.3
Obara, S.4
-
100
-
-
0027463973
-
Thermal behavior of drugs from binary and ternary systems
-
Veiga, M. D., M. J. Bernard, and C. Escobar. 1993. Thermal behavior of drugs from binary and ternary systems. Int J Pharm 89:119-124.
-
(1993)
Int J Pharm
, vol.89
, pp. 119-124
-
-
Veiga, M.D.1
Bernard, M.J.2
Escobar, C.3
-
101
-
-
28044442973
-
Physicochemical studies on solid dispersions of poorly water-soluble drugs. Evaluation of capabilities and limitations of thermal analysis techniques
-
Bikiaris, D., G. Z. Papageorgiou, A. Stergiou, E. Pavlidou, E. Karavas, F. Kanaze, and M. Georgarakis. 2005. Physicochemical studies on solid dispersions of poorly water-soluble drugs. Evaluation of capabilities and limitations of thermal analysis techniques. Thermochnica Acta 439:58-67.
-
(2005)
Thermochnica Acta
, vol.439
, pp. 58-67
-
-
Bikiaris, D.1
Papageorgiou, G.Z.2
Stergiou, A.3
Pavlidou, E.4
Karavas, E.5
Kanaze, F.6
Georgarakis, M.7
-
102
-
-
16844377344
-
Study of pharmaceutical solid dispersions by microthermal analysis
-
Galop, M. 2005. Study of pharmaceutical solid dispersions by microthermal analysis. Pharm Res 22:293-302.
-
(2005)
Pharm Res
, vol.22
, pp. 293-302
-
-
Galop, M.1
-
103
-
-
21644476482
-
A mechanistic investigation of an amorphous pharmaceutical and its solid dispersion, Part I: A comparative analysis by thermally stimulated depolarization current and differential scanning calorimetry
-
Shmeis, R. A., Z. Wang, and S. L. Krill. 2004. A mechanistic investigation of an amorphous pharmaceutical and its solid dispersion, Part I: A comparative analysis by thermally stimulated depolarization current and differential scanning calorimetry. Pharm Res 21:2025-2030.
-
(2004)
Pharm Res
, vol.21
, pp. 2025-2030
-
-
Shmeis, R.A.1
Wang, Z.2
Krill, S.L.3
-
104
-
-
85123269981
-
-
Paper presented at AAPS Annual Meeting, Toronto, October 8, 2002
-
Vasanthavada, M., Z. Wang, Y. Joshi, and M. S. Kislalioglu. 2002. Comparison of the utility of thermally stimulated current and modulated differential scanning calorimeter to study sub-glass transition molecular motions of poly(vinylpyrrolidone). Paper presented at AAPS Annual Meeting, Toronto, October 8, 2002.
-
(2002)
Comparison of the utility of thermally stimulated current and modulated differential scanning calorimeter to study sub-glass transition molecular motions of poly(vinylpyrrolidone)
-
-
Vasanthavada, M.1
Wang, Z.2
Joshi, Y.3
Kislalioglu, M.S.4
-
105
-
-
0031423468
-
Spectroscopic characterization of interactions between PVP and Indomethacin in amorphous molecular dispersions
-
Taylor, L. S. and G. Zografi. 1997. Spectroscopic characterization of interactions between PVP and Indomethacin in amorphous molecular dispersions. Pharm Res 14:1691-1698.
-
(1997)
Pharm Res
, vol.14
, pp. 1691-1698
-
-
Taylor, L.S.1
Zografi, G.2
-
106
-
-
24044499657
-
Molecular properties of ibuprofen and its solid dispersions with Eudragit RL 100 studies by solid-state nuclear magnetic resonance
-
Geppi, M., S. Guccione, G. Mollica, R. Pignatello, and C. A. Veracini. 2005. Molecular properties of ibuprofen and its solid dispersions with Eudragit RL 100 studies by solid-state nuclear magnetic resonance. Pharm Res 22:1544-1555.
-
(2005)
Pharm Res
, vol.22
, pp. 1544-1555
-
-
Geppi, M.1
Guccione, S.2
Mollica, G.3
Pignatello, R.4
Veracini, C.A.5
-
107
-
-
3543091054
-
Solid-state NMR perspective of drug-polymer solid solutions: A model system based on poly(ethyleneoxide)
-
Schachter, D. M., J. Xiong, and G. C. Tirol. 2004. Solid-state NMR perspective of drug-polymer solid solutions: A model system based on poly(ethyleneoxide). Int J Pharm 281:89-101.
-
(2004)
Int J Pharm
, vol.281
, pp. 89-101
-
-
Schachter, D.M.1
Xiong, J.2
Tirol, G.C.3
-
108
-
-
0037074108
-
The mechanism of drug release from solid dispersions in water-soluble polymers
-
Craig, D. Q. M. 2002. The mechanism of drug release from solid dispersions in water-soluble polymers. Int J Pharm 231:131-144.
-
(2002)
Int J Pharm
, vol.231
, pp. 131-144
-
-
Craig, D.Q.M.1
-
109
-
-
0032809138
-
Selection of dosage form composition through drug-excipient compatibility testing
-
Serajuddin, A. T. M., A. B. Thakur, R. N. Ghoshal, M. G. Fakes, S. A. Ranadive, K. R. Morris, and S.A. Varia. 1999. Selection of dosage form composition through drug-excipient compatibility testing. J Pharm Sci 88:696-704.
-
(1999)
J Pharm Sci
, vol.88
, pp. 696-704
-
-
Serajuddin, A.T.M.1
Thakur, A.B.2
Ghoshal, R.N.3
Fakes, M.G.4
Ranadive, S.A.5
Morris, K.R.6
Varia, S.A.7
-
110
-
-
0031775624
-
Factors affecting zero-order release kinetics of porous gelatin capsules
-
Chen, G. L. and W. H. Hao. 1998. Factors affecting zero-order release kinetics of porous gelatin capsules. Drug Dev Ind Pharm 24:557-562.
-
(1998)
Drug Dev Ind Pharm
, vol.24
, pp. 557-562
-
-
Chen, G.L.1
Hao, W.H.2
-
111
-
-
0021216906
-
Degradation of feprostalene in polyethylene glycol 400 solution
-
Johnson, D. M. and W. F. Taylor. 1984. Degradation of feprostalene in polyethylene glycol 400 solution. J Pharm Sci 73:1414-1417.
-
(1984)
J Pharm Sci
, vol.73
, pp. 1414-1417
-
-
Johnson, D.M.1
Taylor, W.F.2
-
112
-
-
0028183005
-
Degradation of O-6-Benzylguanine in aqueous polyethylene glycol 400 (PEG 400) solutions: Concerns with formaldehyde in PEG 400
-
Bindra, D. S., T. D. Williams, and V. J. Stella. 1994. Degradation of O-6-Benzylguanine in aqueous polyethylene glycol 400 (PEG 400) solutions: Concerns with formaldehyde in PEG 400. Pharm Res 11:1060-1064.
-
(1994)
Pharm Res
, vol.11
, pp. 1060-1064
-
-
Bindra, D.S.1
Williams, T.D.2
Stella, V.J.3
-
113
-
-
0031823605
-
Formation of formaldehyde and peroxides by air oxidation of high purity polyoxyethylene surfactants
-
Bergh, M., K. Magnusson, J. Lars, G. Nilson, and A. T. Karlberg. 1998. Formation of formaldehyde and peroxides by air oxidation of high purity polyoxyethylene surfactants. Contact Dermatitis 39:14-20.
-
(1998)
Contact Dermatitis
, vol.39
, pp. 14-20
-
-
Bergh, M.1
Magnusson, K.2
Lars, J.3
Nilson, G.4
Karlberg, A.T.5
-
114
-
-
0028924016
-
Formationofformaldehydeinpolyethyleneglycolandinpoloxamer under stress conditions
-
Frontini, R. and J. B. Mielck. 1995. Formationofformaldehydeinpolyethyleneglycolandinpoloxamer under stress conditions. Int J Pharm 114:121-123.
-
(1995)
Int J Pharm
, vol.114
, pp. 121-123
-
-
Frontini, R.1
Mielck, J.B.2
-
115
-
-
15144358594
-
Contact allergens from surfactants. Atmospheric oxidation of polyoxyethylene alcohols, formation of ethoxylated aldehydes, and their allergenic activity
-
Bergh, M., L. P. Shao, G. Hagelthorn, E. Gafvert, J. L. G. Nilsson, and A. T. Karlberg. 1998. Contact allergens from surfactants. Atmospheric oxidation of polyoxyethylene alcohols, formation of ethoxylated aldehydes, and their allergenic activity. J Pharm Sci 87:276-282.
-
(1998)
J Pharm Sci
, vol.87
, pp. 276-282
-
-
Bergh, M.1
Shao, L.P.2
Hagelthorn, G.3
Gafvert, E.4
Nilsson, J.L.G.5
Karlberg, A.T.6
-
116
-
-
0022650603
-
The current status of solid dispersions
-
Ford, J. L. 1986. The current status of solid dispersions. Pharm Acta Helv 61:69-88.
-
(1986)
Pharm Acta Helv
, vol.61
, pp. 69-88
-
-
Ford, J.L.1
-
117
-
-
0017639968
-
Pharmaceutical applications of solid dispersions: X-ray diffraction and aqueous solubility studies on griseofulvin-poly(ethylene glycol) 6000 systems
-
Chiou, W. L. 1977. Pharmaceutical applications of solid dispersions: X-ray diffraction and aqueous solubility studies on griseofulvin-poly(ethylene glycol) 6000 systems. J Pharm Sci 66:989-991.
-
(1977)
J Pharm Sci
, vol.66
, pp. 989-991
-
-
Chiou, W.L.1
-
118
-
-
0031879728
-
Some factors influencing the dissolution of solid dispersions with nicotinamide and hydroxypropylmethylcellulose as combined carriers
-
Suzuki, H. and H. Sunada. 1998. Some factors influencing the dissolution of solid dispersions with nicotinamide and hydroxypropylmethylcellulose as combined carriers. Chem Pharm Bull 46:1015-1020.
-
(1998)
Chem Pharm Bull
, vol.46
, pp. 1015-1020
-
-
Suzuki, H.1
Sunada, H.2
-
119
-
-
0026552636
-
Elaboration and physical study of an oxodipine solid dispersion in order to formulate tablets
-
Guillaume, F. and A. M. Guyot-Hermann. 1992. Elaboration and physical study of an oxodipine solid dispersion in order to formulate tablets. Drug Dev Ind Pharm 18:811-829.
-
(1992)
Drug Dev Ind Pharm
, vol.18
, pp. 811-829
-
-
Guillaume, F.1
Guyot-Hermann, A.M.2
-
120
-
-
32344439711
-
Enhancing the bioavailability of cyclosporine A using solid dispersion containing polyoxyethylene (40) stearate
-
Liu, C., J. Wu, B. Shi, Y. Zhang, T. Gao, and Y. Pei. 2006. Enhancing the bioavailability of cyclosporine A using solid dispersion containing polyoxyethylene (40) stearate. Drug Dev Ind Pharm 32:115-123.
-
(2006)
Drug Dev Ind Pharm
, vol.32
, pp. 115-123
-
-
Liu, C.1
Wu, J.2
Shi, B.3
Zhang, Y.4
Gao, T.5
Pei, Y.6
-
121
-
-
0035861398
-
Molecular mobility of amorphous pharmaceuticals determined using differential scanning calorimetry
-
Hancock, B. C. and S. L. Shamblin. 2001. Molecular mobility of amorphous pharmaceuticals determined using differential scanning calorimetry. Thermochim Acta 380:95-107.
-
(2001)
Thermochim Acta
, vol.380
, pp. 95-107
-
-
Hancock, B.C.1
Shamblin, S.L.2
-
122
-
-
0031807819
-
Mixing behavior of colyophilized binary systems
-
Shamblin, S. L., L. S. Taylor, and G. Zografi. 1998. Mixing behavior of colyophilized binary systems. J Pharm Sci 87:694-701.
-
(1998)
J Pharm Sci
, vol.87
, pp. 694-701
-
-
Shamblin, S.L.1
Taylor, L.S.2
Zografi, G.3
-
123
-
-
0033025189
-
The relevance of the amorphous state to pharmaceutical dosage forms: Glassy drugs and freeze dried systems
-
Craig, D. Q. M., P. G. Royall, V. L. Kett, and M. L. Hopton. 1999. The relevance of the amorphous state to pharmaceutical dosage forms: Glassy drugs and freeze dried systems. Int J Pharm 179:179-207.
-
(1999)
Int J Pharm
, vol.179
, pp. 179-207
-
-
Craig, D.Q.M.1
Royall, P.G.2
Kett, V.L.3
Hopton, M.L.4
-
124
-
-
0033624390
-
Crystallization inhibition in solid dispersions of MK-0591 and poly(vinylpyrrolidone) polymer
-
Khougaz, K. and S. D. Clas. 2000. Crystallization inhibition in solid dispersions of MK-0591 and poly(vinylpyrrolidone) polymer. J Pharm Sci 89:1325-1334.
-
(2000)
J Pharm Sci
, vol.89
, pp. 1325-1334
-
-
Khougaz, K.1
Clas, S.D.2
-
125
-
-
0028495142
-
Translational and rotational molecular motion in supercooled liquids studies by NMR and forced Rayleigh scattering
-
Chang, I., F. Fujara, B. Geil, G. Heuberger, T. Mangel, and H. J. Sillescu. 1994. Translational and rotational molecular motion in supercooled liquids studies by NMR and forced Rayleigh scattering. J Non Crys Solids 172:248-255.
-
(1994)
J Non Crys Solids
, vol.172
, pp. 248-255
-
-
Chang, I.1
Fujara, F.2
Geil, B.3
Heuberger, G.4
Mangel, T.5
Sillescu, H.J.6
-
126
-
-
33749447574
-
A comparison of the physical stability of amorphous felodipine and nifedipine systems
-
Marsac, P. J., H. Konno, and L. S. Taylor. 2006. A comparison of the physical stability of amorphous felodipine and nifedipine systems. Pharm Res 23:2306-2316.
-
(2006)
Pharm Res
, vol.23
, pp. 2306-2316
-
-
Marsac, P.J.1
Konno, H.2
Taylor, L.S.3
-
127
-
-
0035991640
-
Physical stability of amorphous pharmaceuticals: Importance of configurational thermodynamic quantities and molecular mobility
-
Zhou, D. G., G. Z. Zhang, D. Law, D. J. W. Grant, and E. A. Schmitt. 2002. Physical stability of amorphous pharmaceuticals: Importance of configurational thermodynamic quantities and molecular mobility. J Pharm Sci 91:1863-1872.
-
(2002)
J Pharm Sci
, vol.91
, pp. 1863-1872
-
-
Zhou, D.G.1
Zhang, G.Z.2
Law, D.3
Grant, D.J.W.4
Schmitt, E.A.5
-
128
-
-
27944497469
-
Dielectric studies of molecular motions in amorphous solid and ultraviscous acetaminophen
-
Johari, G. P., S. Kim, and R. M. Shanker. 2005. Dielectric studies of molecular motions in amorphous solid and ultraviscous acetaminophen. J Pharm Sci 94:2207-2223.
-
(2005)
J Pharm Sci
, vol.94
, pp. 2207-2223
-
-
Johari, G.P.1
Kim, S.2
Shanker, R.M.3
-
129
-
-
33646689478
-
Sructural relaxation of acetaminophen glass
-
Gunawan, L., G. P. Johari, and R. M. Shanker. 2006. Sructural relaxation of acetaminophen glass. Pharm Res 23:967-979.
-
(2006)
Pharm Res
, vol.23
, pp. 967-979
-
-
Gunawan, L.1
Johari, G.P.2
Shanker, R.M.3
-
130
-
-
33749439050
-
Predictions of onset of crystallization from experimental relaxation times I-correlation of molecular mobility from temperatures above the glass transition to temperatures below the glass transition
-
Bhugra, C., R. Shmeis, S. L. Krill, and M. J. Pikal. 2006. Predictions of onset of crystallization from experimental relaxation times I-correlation of molecular mobility from temperatures above the glass transition to temperatures below the glass transition. Pharm Res 23:2277-2290.
-
(2006)
Pharm Res
, vol.23
, pp. 2277-2290
-
-
Bhugra, C.1
Shmeis, R.2
Krill, S.L.3
Pikal, M.J.4
-
131
-
-
33846143481
-
A calorimetric investigation of thermodynamic and molecular mobility contributions to the physical stability of two pharmaceutical glasses
-
Zhou, D., D. J. W. Grant, G. G. Z. Zhang, D. Law, and E. A. Schmitt. 2007. A calorimetric investigation of thermodynamic and molecular mobility contributions to the physical stability of two pharmaceutical glasses. J Pharm Sci 96:71-83.
-
(2007)
J Pharm Sci
, vol.96
, pp. 71-83
-
-
Zhou, D.1
Grant, D.J.W.2
Zhang, G.G.Z.3
Law, D.4
Schmitt, E.A.5
-
132
-
-
17644414570
-
Phase behavior of amorphous molecular dispersions I: Determination of the degree and mechanism of solid solubility
-
Vasanthavada, M., W. Tong, Y. Joshi, and M. S. Kislalioglu. 2004. Phase behavior of amorphous molecular dispersions I: Determination of the degree and mechanism of solid solubility. Pharm Res 21:1598-1606.
-
(2004)
Pharm Res
, vol.21
, pp. 1598-1606
-
-
Vasanthavada, M.1
Tong, W.2
Joshi, Y.3
Kislalioglu, M.S.4
-
133
-
-
17644395269
-
Phase behavior of amorphous molecular dispersions II: Role of hydrogen bonding in solid solubility and phase separation kinetics
-
Vasanthavada, M., W. Tong, Y. Joshi, and M. S. Kislalioglu. 2005. Phase behavior of amorphous molecular dispersions II: Role of hydrogen bonding in solid solubility and phase separation kinetics. Pharm Res 22:440-448.
-
(2005)
Pharm Res
, vol.22
, pp. 440-448
-
-
Vasanthavada, M.1
Tong, W.2
Joshi, Y.3
Kislalioglu, M.S.4
-
134
-
-
19444378390
-
Physical stability of the amorphous state of loperamide and two fragment molecules in solid dispersions with the polymers PVP-K30 and PVP-VA64
-
Weuts, I., D. Kempen, A. Decorte, G. Verreck, J. Peeters, M. Brewster, and G. Van den Mooter. 2005. Physical stability of the amorphous state of loperamide and two fragment molecules in solid dispersions with the polymers PVP-K30 and PVP-VA64. Eur J Pharm Sci 25:313-320.
-
(2005)
Eur J Pharm Sci
, vol.25
, pp. 313-320
-
-
Weuts, I.1
Kempen, D.2
Decorte, A.3
Verreck, G.4
Peeters, J.5
Brewster, M.6
Van den Mooter, G.7
|