Investigation of formulation approaches to improve the dissolution of SB-210661, a poorly water soluble 5-lipoxygenase inhibitor

International Journal of Pharmaceutics

Volumn 176, Issue 1, 1998, Pages 31-38

  Perng, Cherng Yih ^a   Kearney, Albert S ^a   Patel, Kamlesh ^a   Palepu, Nagesh R ^a   Zuber, Gary ^b  

^a SmithKline Beecham P   (United States)

^b NONE   (United States)

Author keywords

5 Lipoxygenase inhibitor; Contact angle; Dissolution; Hydrogen bonding; SB 210661; Solid dispersion; Surfactants

Indexed keywords

DODECYL SULFATE SODIUM; LIPOXYGENASE INHIBITOR; MICROCRYSTALLINE CELLULOSE; POLYSORBATE 40; SB 210661; SURFACTANT; UNCLASSIFIED DRUG;

ARTICLE; CONTACT ANGLE; DISPERSION; DISSOLUTION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STORAGE; INFRARED SPECTROSCOPY; PRIORITY JOURNAL; SURFACE TENSION; X RAY DIFFRACTION;

EID: 0031725929     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(98)00296-8     Document Type: Article

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