Scientific Opinion on Dietary Reference Values for iodine

EFSA Journal

Volumn 12, Issue 5, 2014, Pages

[No Author Info available]

Author keywords

Adequate Intake; Dietary Reference Value; goitre; iodine

Indexed keywords

EID: 85075313552     PISSN: None     EISSN: 18314732     Source Type: Journal    
DOI: 10.2903/j.efsa.2014.3660     Document Type: Article

References (288)

1. Aboul-Khair SA, Crooks J, Turnbull AC and Hytten FE, 1964. The physiological changes in thyroid function during pregnancy. Clinical Science, 27, 195–207.
2. Afssa (Agence française de sécurité sanitaire des aliments), 2001. Apports nutritionnels conseillés pour la population française. Editions Tec&Doc, Paris, France, 605 pp.
3. Ain KB, Mori Y and Refetoff S, 1987. Reduced clearance rate of thyroxine-binding globulin (TBG) with increased sialylation: a mechanism for estrogen-induced elevation of serum TBG concentration. Journal of Clinical Endocrinology and Metabolism, 65, 689–696.
4. Ainy E, Ordookhani A, Hedayati M and Azizi F, 2007. Assessment of intertrimester and seasonal variations of urinary iodine concentration during pregnancy in an iodine-replete area. Clinical Endocrinology, 67, 577–581.
5. Alexander EK, Marqusee E, Lawrence J, Jarolim P, Fischer GA and Larsen PR, 2004. Timing and magnitude of increases in levothyroxine requirements during pregnancy in women with hypothyroidism. New England Journal of Medicine, 351, 241–249.
6. Alfred Rusescu Institute for Mother and Child Care, 2005. Nutritional status of pregnant women, children under 5 years old and schoolchildren aged 6–7 years. Romania. A study conducted in cooperation and with the support of the UNICEF Representative Office in Romania. 20 pp.
7. Allain P, Berre S, Krari N, Laine-Cessac P, Le Bouil A, Barbot N, Rohmer V and Bigorgne JC, 1993. Use of plasma iodine assay for diagnosing thyroid disorders. Journal of Clinical Pathology, 46, 453–455.
8. Alvarez-Pedrerol M, Guxens M, Mendez M, Canet Y, Martorell R, Espada M, Plana E, Rebagliato M and Sunyer J, 2009. Iodine levels and thyroid hormones in healthy pregnant women and birth weight of their offspring. European Journal of Endocrinology, 160, 423–429.
9. Andersen S, Pedersen KM, Iversen F, Terpling S, Gustenhoff P, Petersen SB and Laurberg P, 2008a. Naturally occurring iodine in humic substances in drinking water in Denmark is bioavailable and determines population iodine intake. British Journal of Nutrition, 99, 319–325.
10. Andersen S, Karmisholt J, Pedersen KM and Laurberg P, 2008b. Reliability of studies of iodine intake and recommendations for number of samples in groups and in individuals. British Journal of Nutrition, 99, 813–818.
11. Andersen SL, Moller M and Laurberg P, 2014. Iodine concentrations in milk and in urine during breastfeeding are differently affected by maternal fluid intake. Thyroid, 24, 764–772.
12. Andersson M, Berg G, Eggertsen R, Filipsson H, Gramatkovski E, Hansson M, Hulthen L, Milakovic M and Nystrom E, 2009. Adequate iodine nutrition in Sweden: a cross-sectional national study of urinary iodine concentration in school-age children. European Journal of Clinical Nutrition, 63, 828–834.
13. Andersson M, Aeberli I, Wust N, Piacenza AM, Bucher T, Henschen I, Haldimann M and Zimmermann MB, 2010. The Swiss iodized salt program provides adequate iodine for school children and pregnant women, but weaning infants not receiving iodine-containing complementary foods as well as their mothers are iodine deficient. Journal of Clinical Endocrinology and Metabolism, 95, 5217–5224.
14. Andersson M, Karumbunathan V and Zimmermann MB, 2012. Global iodine status in 2011 and trends over the past decade. Journal of Nutrition, 142, 744–750.
15. Anonymous, 1869. Goitre en Savoie. Journal de la Société de Statistique de Paris, 10.
16. Antonangeli L, Maccherini D, Cavaliere R, Di Giulio C, Reinhardt B, Pinchera A and Aghini-Lombardi F, 2002. Comparison of two different doses of iodide in the prevention of gestational goiter in marginal iodine deficiency: a longitudinal study. European Journal of Endocrinology, 147, 29–34.
17. Aquaron R, Delange F, Marchal P, Lognone V and Ninane L, 2002. Bioavailability of seaweed iodine in human beings. Cellular and Molecular Biology, 48, 563–569.
18. Ares S, Quero J and De Escobar GM, 2008. Iodine balance, iatrogenic excess, and thyroid dysfunction in premature newborns. Seminars in Perinatology, 32, 407–412.
19. Ascoli W and Arroyave G, 1970. Epidemiología del bocio endémico en Centro América. Relación entre prevalencia y excreción urinaria de yodo. Archivos Latinoamericanos de Nutricion, 20, 13 pp.
20. Azizi F and Smyth P, 2009. Breastfeeding and maternal and infant iodine nutrition. Clinical Endocrinology, 70, 803–809.
21. Bader N, Moller U, Leiterer M, Franke K and Jahreis G, 2005. Pilot study: tendency of increasing iodine content in human milk and cow's milk. Experimental and Clinical Endocrinology and Diabetes, 113, 8–12.
22. Baer DJ, Fong AK, Novotny JA and Oexmann MJ, 1999. Compartmental modeling, stable isotopes and balance studies. In: Well-Controlled Diet Studies in Humans, A Practical Guide to Design and Management. Ed Dennis B. American Dietetic Association, Chicago, USA, pp. 238–254.
23. Bath SC, Steer CD, Golding J, Emmett P and Rayman MP, 2013a. Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC). Lancet, 382, 331–337.
24. Bath SC, Jolly KB and Rayman MP, 2013b. Iodine supplements during and after pregnancy. JAMA, 309, 1345.
25. Berghout A and Wiersinga W, 1998. Thyroid size and thyroid function during pregnancy: an analysis. European Journal of Endocrinology, 138, 536–542.
26. Bernard JD, McDonald RA and Nesmith JA, 1970. New normal ranges for the radioiodine uptake study. Journal of Nuclear Medicine, 11, 449–451.
27. Berson SA, Yalow RS, Sorrentino J and Roswit B, 1952. The determination of thyroidal and renal plasma I131 clearance rates as a routine diagnostic test of thyroid dysfunction. Journal of Clinical Investigation, 31, 141–158.
28. Biondi B and Cooper DS, 2008. The clinical significance of subclinical thyroid dysfunction. Endocrine Reviews, 29, 76–131.
29. Bittermann H, 1999. Iodine supply of German conscripts at age 17.5–21 years. Doctoral thesis, Charité, Berlin.
30. Bizhanova A and Kopp P, 2009. Minireview: The sodium-iodide symporter NIS and pendrin in iodide homeostasis of the thyroid. Endocrinology, 150, 1084–1090.
31. Böhles H, Aschenbrenner M, Roth M, Von Loewenich V, Ball F and Usadel KH, 1993. Development of thyroid gland volume during the first 3 months of life in breast-fed versus iodine-supplemented and iodine-free formula-fed infants. Clinical Investigator, 71, 13–20.
32. Bonofiglio D, Catalano S, Perri A, Baldini MP, Marsico S, Tagarelli A, Conforti D, Guido R and Ando S, 2009. Beneficial effects of iodized salt prophylaxis on thyroid volume in an iodine deficient area of southern Italy. Clinical Endocrinology, 71, 124–129.
33. Bottazzo GF, 1981. Thyroid growth-blocking antibodies in autoimmune (AI) atrophic thyroiditis. Annales d'Endocrinologie 42, 13A.
34. Bougma K, Aboud FE, Harding KB and Marquis GS, 2013. Iodine and mental development of children 5 years old and under: a systematic review and meta-analysis. Nutrients, 5, 1384–1416.
35. Braverman LE and Utiger RD, 1991. Werner and Ingbar's The Thyroid. A fundamental and clinical text. Lippincott Williams & Wilkins, Philadelphia, USA, 1365 pp.
36. Bregengard C, Kirkegaard C, Faber J, Poulsen S, Hasselstrom K, Siersbaek-Nielsen K and Friis T, 1987. Relationships between serum thyrotropin, serum free thyroxine (T4), and 3,5,3′-triiodothyronine (T3) and the daily T4 and T3 production rates in euthyroid patients with multinodular goiter. Journal of Clinical Endocrinology and Metabolism, 65, 258–261.
37. Buchinger W, Lorenz-Wawschinek O, Semlitsch G, Langsteger W, Binter G, Bonelli RM and Eber O, 1997. Thyrotropin and thyroglobulin as an index of optimal iodine intake: correlation with iodine excretion of 39,913 euthyroid patients. Thyroid, 7, 593–597.
38. Burns R, O'Herlihy C and Smyth PP, 2011a. The placenta as a compensatory iodine storage organ. Thyroid, 21, 541–546.
39. Burns R, Azizi F, Hedayati M, Mirmiran P, O'Herlihy C and Smyth PP, 2011b. Is placental iodine content related to dietary iodine intake? Clinical Endocrinology, 75, 261–264.
40. Busnardo B, Nacamulli D, Frigato F, Vianello-Dri A, De Vido D, Mian C, Candiani F, Tomasella G, Zambonin L, Piccolo M and Girelli ME, 2003. Normal values for thyroid ultrasonography, goiter prevalence and urinary iodine concentration in schoolchildren of the Veneto Region, Italy. Journal of Endocrinological Investigation, 26, 991–996.
41. Butte NF, Lopez-Alarcon MG and Garza C, 2002. Nutrient adequacy of exclusive breastfeeding for the term infant during the first six months of life. World Health Organization, 57 pp.
42. Cao XY, Jiang XM, Dou ZH, Rakeman MA, Zhang ML, O'Donnell K, Ma T, Amette K, DeLong N and DeLong GR, 1994. Timing of vulnerability of the brain to iodine deficiency in endemic cretinism. New England Journal of Medicine, 331, 1739–1744.
43. Capdevila Bert R, Marsal Mora JR, Pujol Salud J and Anguera Farran R, 2010. [Prevalence study of iodine deficiency in a 6-year-old school population]. An Pediatr (Barc), 72, 331–338.
44. Cardoso BA and Rosenthal D, 1987. Thyroxine (T4) and triiodothyronine (T3) metabolism in normal subjects from Rio de Janeiro, Brazil. Brazilian Journal of Medical and Biological Research, 20, 419–423.
45. Caron P, Hoff M, Bazzi S, Dufor A, Faure G, Ghandour I, Lauzu P, Lucas Y, Maraval D, Mignot F, Ressigeac P, Vertongen F and Grange V, 1997. Urinary iodine excretion during normal pregnancy in healthy women living in the southwest of France: correlation with maternal thyroid parameters. Thyroid, 7, 749–754.
46. Castetbon K, Vernay M, Malon A, Salanave B, Deschamps V, Roudier C, Oleko A, Szego E and Hercberg S, 2009. Dietary intake, physical activity and nutritional status in adults: the French nutrition and health survey (ENNS, 2006–2007). British Journal of Nutrition, 102, 733–743.
47. Chanoine JP, Toppet V, Lagasse R, Spehl M and Delange F, 1991. Determination of thyroid volume by ultrasound from the neonatal period to late adolescence. European Journal of Pediatrics, 150, 395–399.
48. Chen ZP and Hetzel BS, 2010. Cretinism revisited. Best Practice and Research. Clinical Endocrinology and Metabolism, 24, 39–50.
49. Cheng SY, Leonard JL and Davis PJ, 2010. Molecular aspects of thyroid hormone actions. Endocrine Reviews, 31, 139–170.
50. Chierici R, Saccomandi D and Vigi V, 1999. Dietary supplements for the lactating mother: influence on the trace element content of milk. Acta Paediatrica. Supplement, 88, 7–13.
51. Chopra IJ, 1976. An assessment of daily production and significance of thyroidal secretion of 3, 3′, 5′-triiodothyronine (reverse T3) in man. Journal of Clinical Investigation, 58, 32–40.
52. Chueire VB, Romaldini JH and Ward LS, 2007. Subclinical hypothyroidism increases the risk for depression in the elderly. Archives of Gerontology and Geriatrics, 44, 21–28.
53. Cole VV and Curtis GM, 1935. Human iodine balance - nine figures. Journal of Nutrition, 10, 493–506.
54. Colzani R, Fang SL, Alex S and Braverman LE, 1998. The effect of nicotine on thyroid function in rats. Metabolism: Clinical and Experimental, 47, 154–157.
55. Combet E and Lean MEJ, 2014. Validation of a short food frequency questionnaire specific for iodine in UK females of childbearing age. Journal of Human Nutrition and Dietetics, Mar 13. doi: 10.1111/jhn.12219 [Epub ahead of print].
56. Consolazio CF, Matoush LO, Nelson RA, Isaac GJ and Canham JE, 1966. Comparisons of nitrogen, calcium and iodine excretion in arm and total body sweat. American Journal of Clinical Nutrition, 18, 443–448.
57. Costa A, De Filippis V, Panizzo M, Giraudi G, Bertino E, Arisio R, Mostert M, Trapani G and Fabris C, 1986. Development of thyroid function between VI-IX month of fetal life in humans. Journal of Endocrinological Investigation, 9, 273–280.
58. Costeira MJ, Oliveira P, Ares S, De Escobar GM and Palha JA, 2009. Iodine status of pregnant women and their progeny in the Minho Region of Portugal. Thyroid, 19, 157–163.
59. Costeira MJ, Oliveira P, Santos NC, Ares S, Saenz-Rico B, De Escobar GM and Palha JA, 2011. Psychomotor development of children from an iodine-deficient region. Journal of Pediatrics, 159, 447–453.
60. D-A-CH (Deutsche Gesellschaft für Ernährung, Österreichische Gesellschaft für Ernährung, Schweizerische Gesellschaft für Ernährungsforschung, Schweizerische Vereinigung für Ernährung), 2013. Referenzwerte für die Nährstoffzufuhr. Neuer Umschau Buchverlag, Frankfurt/Main, Germany, 292 pp.
61. Dafnis E and Sabatini S, 1992. The effect of pregnancy on renal function: physiology and pathophysiology. American Journal of the Medical Sciences, 303, 184–205.
62. Davis PJ, Lin HY, Mousa SA, Luidens MK, Hercbergs AA, Wehling M and Davis FB, 2011. Overlapping nongenomic and genomic actions of thyroid hormone and steroids. Steroids, 76, 829–833.
63. DeGroot LJ, 1966. Kinetic analysis of iodine metabolism. Journal of Clinical Endocrinology and Metabolism, 26, 149–173.
64. Delange F, Bourdoux P, Vo Thi LD, Ermans AM and Senterre J, 1984. Negative iodine balance in preterm infants. Annales d' Endocrinologie, 45, 77.
65. Delange F, Fisher DA, Glinoer D and North Atlantic Treaty Organization Scientific Affairs Division, 1989. Research in congenital hypothyroidism. Plenum Press, New York, USA, pp. 367.
66. Delange F and Ermans A-M, 1991. Iodine deficiency. In: Werner and Ingbar's The Thyroid. A fundamental and clinical text. Eds Braverman LE and Utiger RD. J.B. Lippincott, Philadelphia, USA, 368–390.
67. Delange F, Dunn JT, Glinoer D and North Atlantic Treaty Organization Scientific Affairs Division, 1993. Iodine deficiency in Europe. A continuing concern. Plenum Press, New York, USA, pp. 492.
68. Delange F, 1994. The disorders induced by iodine deficiency. Thyroid, 4, 107–128.
69. Delange F, Benker G, Caron P, Eber O, Ott W, Peter F, Podoba J, Simescu M, Szybinsky Z, Vertongen F, Vitti P, Wiersinga W and Zamrazil V, 1997. Thyroid volume and urinary iodine in European schoolchildren: standardization of values for assessment of iodine deficiency. European Journal of Endocrinology, 136, 180–187.
70. Delange F, Wolff P, Gnat D, Dramaix M, Pilchen M and Vertongen F, 2001. Iodine deficiency during infancy and early childhood in Belgium: does it pose a risk to brain development? European Journal of Pediatrics, 160, 251–254.
71. Delgado E, Diaz-Cadórniga, Tarton T, Bobis ML, Valdés MM and Méndez YA, 2004. Erradicación de los trastornos por deficienca de yodo en Asturias (España): 18 años de yodoprofilaxis con sal. Endocrinología y Nutrición, 51, 492–496.
72. DH (Department of Health), 1991. Dietary reference values for food energy and nutrients for the United Kingdom. Report of the Panel on Dietary Reference Values of the Committee on Medical Aspects of Food Policy. HMSO, London, UK, 212 pp.
73. Di Cosmo C, Fanelli G, Tonacchera M, Ferrarini E, Dimida A, Agretti P, De Marco G, Vitti P, Pinchera A, Bevilacqua G, Naccarato AG and Viacava P, 2006. The sodium-iodide symporter expression in placental tissue at different gestational age: an immunohistochemical study. Clinical Endocrinology, 65, 544–548.
74. Doerge DR and Sheehan DM, 2002. Goitrogenic and estrogenic activity of soy isoflavones. Environmental Health Perspectives, 110 Suppl 3, 349–353.
75. Dohan O and Carrasco N, 2003. Advances in Na(+)/I(-) symporter (NIS) research in the thyroid and beyond. Molecular and Cellular Endocrinology, 213, 59–70.
76. Dorea JG, 2002. Iodine nutrition and breast feeding. Journal of Trace Elements in Medicine and Biology, 16, 207–220.
77. Drees (Direction des études de l'évaluation et des statistiques), 2011. L'état de santé de la population en France. Suivi des objectifs annexés à la loi de santé publique. Rapport 2011. 340 pp.
78. Dunn JT, Semigran MJ and Delange F, 1998. The prevention and management of iodine-induced hyperthyroidism and its cardiac features. Thyroid, 8, 101–106.
79. Dworkin HJ, Jacquez JA and Beierwaltes WH, 1966. Relationship of iodine ingestion to iodine excretion in pregnancy. Journal of Clinical Endocrinology and Metabolism, 26, 1329–1342.
80. EFSA (European Food Safety Authority), 2005. Scientific Opinion of the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) on the use of iodine in feedingstuffs. The EFSA Journal 2005, 168, 1–42. doi:10.2903/j.efsa.2005.168.
81. EFSA ANS Panel (EFSA Panel on Food Additives and Nutrient Sources added to Food), 2013. Statement on the safety of iodized ethyl esters of poppy seed oil as a source of iodine added for nutritional purposes to foodstuffs. EFSA Journal 2013;11(3):3120, 10 pp. doi:10.2903/j.efsa.2013.3120.
82. EFSA (European Food Safety Authority), 2008. Scientific Opinion of the Panel on Contaminants in the Food Chain on a request from the European Commission on glucosinolates as undesirable substances in animal feed. The EFSA Journal 2008, 590, 1–76. doi:10.2903/j.efsa.2008.590.
83. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2009. Scientific Opinion on the appropriate age for introduction of complementary feeding of infants. EFSA Journal 2009;7(12):1423, 38 pp. doi:10.2903/j.efsa.2009.1423.
84. EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2010. Scientific Opinion on Dietary Reference Values for water. EFSA Journal 2010;8(3):1459, 48 pp. doi:10.2903/j.efsa.2010.1459.
85. Elnagar B, Eltom A, Wide L, Gebre-Medhin M and Karlsson FA, 1998. Iodine status, thyroid function and pregnancy: study of Swedish and Sudanese women. European Journal of Clinical Nutrition, 52, 351–355.
86. Eltom A, Eltom M, Elnagar B, Elbagir M and Gebre-Medhin M, 2000. Changes in iodine metabolism during late pregnancy and lactation: a longitudinal study among Sudanese women. European Journal of Clinical Nutrition, 54, 429–433.
87. Erdogan G, Sav H and Erdogan MF, 2000. Iodine status and thyroid volumes of school age children from Northern Cyprus. Journal of Endocrinological Investigation, 23, 74–77.
88. Etling N, 1977. Concentration of thyroglobulin, iodine contents of thyroglobulin and of iodoaminoacids in human neonates thyroid glands. Acta Paediatrica Scandinavica, 66, 97–102.
89. Etling N, Padovani E, Gehin-Fouque F and Tato L, 1983. Iodine and thyroid hormone levels in serum and urine of full term newborn infants. Helvetica Paediatrica Acta, 38, 117–122.
90. Etling N and Gehin-Fouque F, 1984. Iodinated compounds and thyroxine binding to albumin in human breast milk. Pediatric Research, 18, 901–903.
91. Etling N, Padovani E, Fouque F and Tato L, 1986. First-month variations in total iodine content of human breast milks. Early Human Development, 13, 81–85.
92. Evans TC, Kretzschmar RM, Hodges RE and Song CW, 1967. Radioiodine uptake studies of the human fetal thyroid. Journal of Nuclear Medicine, 8, 157–165.
93. Faber J, Poulsen S, Iversen P and Kirkegaard C, 1988. Thyroid hormone turnover in patients with small cell carcinoma of the lung. Acta Endocrinologica, 118, 460–464.
94. FAO/WHO (Food and Agriculture Organization of the United Nations/World Health Organization), 2011. Evaluation of certain contaminants in food. 72nd report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series 959, 115 pp.
95. FAO/WHO/UNU (Food and Agriculture Organization of the United Nations/World Health Organization/United Nations University), 2004. Human energy requirements. Report of a Joint FAO/WHO/UNU Expert Consultation: Rome, 17–24 October 2001. FAO food and nutrition technical report series, 103 pp.
96. Farkas I, Sajgo K and 1997. Goiter frequency among boys of I-IV class of primary schools: reports to the Ministry of Health 94/95, 95/96, 96, 97. Public Health of Budapest; 1 15–9.
97. Fish LH, Schwartz HL, Cavanaugh J, Steffes MW, Bantle JP and Oppenheimer JH, 1987. Replacement dose, metabolism, and bioavailability of levothyroxine in the treatment of hypothyroidism. Role of triiodothyronine in pituitary feedback in humans. New England Journal of Medicine, 316, 764–770.
98. Fisher DA and Oddie TH, 1969a. Thyroid iodine content and turnover in euthyroid subjects: validity of estimation of thyroid iodine accumulation from short-term clearance studies. Journal of Clinical Endocrinology and Metabolism, 29, 721–727.
99. Fisher DA and Oddie TH, 1969b. Thyroidal radioiodine clearance and thryoid iodine accumulation: contrast between random daily variation and population data. Journal of Clinical Endocrinology and Metabolism, 29, 111–115.
100. Fister P, Gaberscek S, Zaletel K, Krhin B, Gersak K and Hojker S, 2009. Thyroid volume changes during pregnancy and after delivery in an iodine-sufficient Republic of Slovenia. European Journal of Obstetrics, Gynecology, and Reproductive Biology, 145, 45–48.
101. Fister P, Gaberscek S, Zaletel K, Krhin B, Hojker S and Gersak K, 2011. Thyroid function in the third trimester of pregnancy and after delivery in an area of adequate iodine intake. International Journal of Gynaecology and Obstetrics, 112, 52–55.
102. Flachowsky G, Franke K, Meyer U, Leiterer M and Schone F, 2014. Influencing factors on iodine content of cow milk. European Journal of Nutrition, 53, 351–365.
103. Follis RH, Jr., Vanprapa K and Damrongsakdi D, 1962. Studies on iodine nutrition in Thailand. Journal of Nutrition, 76, 159–173.
104. Forth W, Henschler D and Rummel W, 1987. Allgemeine und spezielle Pharmakologie und Toxikologie. Wissenschaftsverlag, Mannheim, 436–443.
105. Fumarola A, Calvanese A and D'Armiento M, 2009. Iodine intake in pregnancy. International Journal of Gynaecology and Obstetrics, 104, 147–148.
106. Gaitan E, 1990. Goitrogens in food and water. Annual Review of Nutrition, 10, 21–39.
107. Garcia-Fuentes E, Gallo M, Garcia L, Prieto S, Alcaide-Torres J, Santiago P, Velasco I and Soriguer F, 2008. Amniotic fluid iodine concentrations do not vary in pregnant women with varying iodine intake. British Journal of Nutrition, 99, 1178–1181.
108. Gardner DF, Centor RM and Utiger RD, 1988. Effects of low dose oral iodide supplementation on thyroid function in normal men. Clinical Endocrinology, 28, 283–288.
109. Gavin L, Castle J, McMahon F, Martin P, Hammond M and Cavalieri RR, 1977. Extrathyroidal conversion of thyroxine to 3,3′,5′-triiodothyronine (reverse-T3) and to 3,5,3′-triiodothyronine (T3) in humans. Journal of Clinical Endocrinology and Metabolism, 44, 733–742.
110. Glinoer D, Lemone M, Bourdoux P, De Nayer P, DeLange F, Kinthaert J and LeJeune B, 1992. Partial reversibility during late postpartum of thyroid abnormalities associated with pregnancy. Journal of Clinical Endocrinology and Metabolism, 74, 453–457.
111. Glinoer D, De Nayer P, Delange F, Lemone M, Toppet V, Spehl M, Grun JP, Kinthaert J and Lejeune B, 1995. A randomized trial for the treatment of mild iodine deficiency during pregnancy: maternal and neonatal effects. Journal of Clinical Endocrinology and Metabolism, 80, 258–269.
112. Glinoer D, 1997. The regulation of thyroid function in pregnancy: pathways of endocrine adaptation from physiology to pathology. Endocrine Reviews, 18, 404–433.
113. Glinoer D, 1998. Iodine supplementation during pregnancy: importance and biochemical assessment. Experimental and Clinical Endocrinology and Diabetes, 106 Suppl 3, S21.
114. Glinoer D, 2001. Pregnancy and iodine. Thyroid, 11, 471–481.
115. Glinoer D, 2007. The importance of iodine nutrition during pregnancy. Public Health Nutrition, 10, 1542–1546.
116. Goellner MH, Ziegler EE and Fomon SJ, 1981. Urination during the first three years of life. Nephron, 28, 174–178.
117. Gokmen IG and Dagli G, 1995. Determination of iodine concentration in human milk, cows' milk and infant formula and estimation of daily iodine intake of infants. Analyst, 120, 2005–2008.
118. Greenberg AH, Czernichow P, Reba RC, Tyson J and Blizzard RM, 1970. Observations on the maturation of thyroid function in early fetal life. Journal of Clinical Investigation, 49, 1790–1803.
119. Gunnarsdottir I and Dahl L, 2012. Iodine intake in human nutrition: a systematic literature review. Food Nutr Res, 56.
120. Gushurst CA, Mueller JA, Green JA and Sedor F, 1984. Breast milk iodide: Reassessment in the 1980s. Pediatrics, 73, 354–357.
121. Gutekunst R, Becker W, Hehrmann R, Olbricht T and Pfannenstiel P, 1988. [Ultrasonic diagnosis of the thyroid gland]. Deutsche Medizinische Wochenschrift, 113, 1109–1112.
122. Harden RM and Alexander WD, 1963. Quantitative aspects of iodide excretion in human thermal sweat. Clinical Science, 25, 79–87.
123. Harrison MT, Harden RM, Alexander WD and Wayne E, 1965. Iodine balance studies in patients with normal and abnormal thyroid function. Journal of Clinical Endocrinology and Metabolism, 25, 1077–1084.
124. Harrison MT, 1968. Iodine balance in man. Postgraduate Medical Journal, 44, 69–71.
125. Hays MT, 1991. Localization of human thyroxine absorption. Thyroid, 1, 241–248.
126. Health Council of the Netherlands, 2008. Towards maintaining an optimum iodine intake. publication no. 2008/14E, The Hague, Netherlands.
127. Heidemann PH, Stubbe P and Thal H, 1986. Influence of iodine prophylaxis on thyroid function and iodine excretion in newborn infants and their mothers: comparison between Sweden and Germany. Acta Endocrinologica, 3, 48–48.
128. Henrichs J, Bongers-Schokking JJ, Schenk JJ, Ghassabian A, Schmidt HG, Visser TJ, Hooijkaas H, De Muinck Keizer-Schrama SM, Hofman A, Jaddoe VV, Visser W, Steegers EA, Verhulst FC, De Rijke YB and Tiemeier H, 2010. Maternal thyroid function during early pregnancy and cognitive functioning in early childhood: the generation R study. Journal of Clinical Endocrinology and Metabolism, 95, 4227–4234.
129. Hooper PL, Turner JR, Conway MJ and Plymate SR, 1980. Thyroid uptake of 123I in a normal population. Archives of Internal Medicine, 140, 757–758.
130. Hynes KL, Otahal P, Hay I and Burgess JR, 2013. Mild iodine deficiency during pregnancy is associated with reduced educational outcomes in the offspring: 9-year follow-up of the gestational iodine cohort. Journal of Clinical Endocrinology and Metabolism, 98, 1954–1962.
131. IDD Newsletter, 2000. IDD in the Baltics. IDD Newsletter; 16.
132. Ingenbleek Y and Malvaux P, 1974. Iodine balance studies in protein-calorie malnutrition. Archives of Disease in Childhood, 49, 305–309.
133. IOM (Institute of Medicine), 2001. Dietary Reference Intakes for vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. National Academies Press, Washington DC, USA, 797 pp.
134. Jahreis G, Hausmann W, Kiessling G, Franke K and Leiterer M, 2001. Bioavailability of iodine from normal diets rich in dairy products-results of balance studies in women. Experimental and Clinical Endocrinology and Diabetes, 109, 163–167.
135. Johner SA, Shi L and Remer T, 2010. Higher urine volume results in additional renal iodine loss. Thyroid, 20, 1391–1397.
136. Jonckheer MH, 1987. Clinical usefulness of thyroid imaging by means of X-ray fluorescence. Hormone Research, 26, 42–47.
137. Kahaly G, Dienes HP, Beyer J and Hommel G, 1997. Randomized, double blind, placebo-controlled trial of low dose iodide in endemic goiter. Journal of Clinical Endocrinology and Metabolism, 82, 4049–4053.
138. Kahaly GJ, Dienes HP, Beyer J and Hommel G, 1998. Iodide induces thyroid autoimmunity in patients with endemic goitre: a randomised, double-blind, placebo-controlled trial. European Journal of Endocrinology, 139, 290–297.
139. Kahaly GJ and Dillmann WH, 2005. Thyroid hormone action in the heart. Endocrine Reviews, 26, 704–728.
140. Kaplan MM, 1992. Monitoring thyroxine treatment during pregnancy. Thyroid, 2, 147–152.
141. Karagiannis G, Ashoor G, Maiz N, Jawdat F and Nicolaides KH, 2011. Maternal thyroid function at eleven to thirteen weeks of gestation and subsequent delivery of small for gestational age neonates. Thyroid, 21, 1127–1131.
142. Kirk AB, Dyke JV, Martin CF and Dasgupta PK, 2007. Temporal patterns in perchlorate, thiocyanate, and iodide excretion in human milk. Environmental Health Perspectives, 115, 182–186.
143. Kirkegaard C, Korner A and Faber J, 1990. Increased production of thyroxine and inappropriately elevated serum thyrotropin in levels in endogenous depression. Biological Psychiatry, 27, 472–476.
144. Knudsen N, Bulow I, Laurberg P, Ovesen L, Perrild H and Jorgensen T, 2002. Association of tobacco smoking with goiter in a low-iodine-intake area. Archives of Internal Medicine, 162, 439–443.
145. Köhrle J and Gärtner R, 2009. Selenium and thyroid. Best Practice and Research. Clinical Endocrinology and Metabolism, 23, 815–827.
146. Kostalova L, 2003. Urinary iodine assessment in children in Slovakia. Bratislava: Children's University Hospital.
147. Kotnik P, Sirca Campa A, Zupancic M, Stimec M, Smole K, Mis NF, Battelino T and Krzisnik C, 2006. Goiter prevalence and urinary iodine concentration in Slovenian adolescents. Thyroid, 16, 769–773.
148. Kovatcheva R, Angelova K, Timcheva T and Vukov M, 2011. Iodine nutrition in Bulgaria. ICCIDD West-Central Europe regional meeting. Satellite to 35th annual ETA meeting. September, 2011, Krakow, Poland.
149. Krassas GE, Poppe K and Glinoer D, 2010. Thyroid function and human reproductive health. Endocrine Reviews, 31, 702–755.
150. Kung AW, Lao TT, Chau MT, Tam SC and Low LC, 2000. Goitrogenesis during pregnancy and neonatal hypothyroxinaemia in a borderline iodine sufficient area. Clinical Endocrinology, 53, 725–731.
151. Kurtoglu S, Akcakus M, Kocaoglu C, Gunes T, Budak N, Atabek ME, Karakucuk I and Delange F, 2004. Iodine status remains critical in mother and infant in Central Anatolia (Kayseri) of Turkey. European Journal of Nutrition, 43, 297–303.
152. Kusic Z, Jukic T, Rogan SA, Juresa V, Dabelic N, Stanicic J, Boric M, Lukinac L, Mihaljevic I, Punda A, Smokvina A, Topalovic Z and Katalenic M, 2012. Current status of iodine intake in Croatia-the results of 2009 survey. Collegium Antropologicum, 36, 123–128.
153. Lahesmaa P and Vilkki P, 1960. The iodine content of human milk in Finland. Acta Paediatrica, 49, 371–376.
154. Lamberg BA, 1986. Endemic goitre in Finland and changes during 30 years of iodine prophylaxis. Endocrinologia Experimentalis, 20, 35–47.
155. Laurberg P, Pedersen KM, Hreidarsson A, Sigfusson N, Iversen E and Knudsen PR, 1998. Iodine intake and the pattern of thyroid disorders: a comparative epidemiological study of thyroid abnormalities in the elderly in Iceland and in Jutland, Denmark. Journal of Clinical Endocrinology and Metabolism, 83, 765–769.
156. Laurberg P, Nohr SB, Pedersen KM and Fuglsang E, 2004. Iodine nutrition in breast-fed infants is impaired by maternal smoking. Journal of Clinical Endocrinology and Metabolism, 89, 181–187.
157. Laurberg P, Andersen S, Bjarnadottir RI, Carle A, Hreidarsson A, Knudsen N, Ovesen L, Pedersen I and Rasmussen L, 2007. Evaluating iodine deficiency in pregnant women and young infants-complex physiology with a risk of misinterpretation. Public Health Nutrition, 10, 1547–1552; discussion 1553.
158. Laurberg P, Cerqueira C, Ovesen L, Rasmussen LB, Perrild H, Andersen S, Pedersen IB and Carle A, 2010. Iodine intake as a determinant of thyroid disorders in populations. Best Practice and Research. Clinical Endocrinology and Metabolism, 24, 13–27.
159. Liberman CS, Pino SC, Fang SL, Braverman LE and Emerson CH, 1998. Circulating iodide concentrations during and after pregnancy. Journal of Clinical Endocrinology and Metabolism, 83, 3545–3549.
160. Limbert E, Prazeres S, Sao Pedro M, Madureira D, Miranda A, Ribeiro M, Carrilho F, Jacome de Castro J, Lopes MS, Cardoso J, Carvalho A, Oliveira MJ, Reguengo H, Borges F and Grupo de Estudos da Tiroide da Sociedade Portuguesa de Endocrinologia Diabetes e M, 2012. [Iodine intake in Portuguese school children]. Acta Medica Portuguesa, 25, 29–36.
161. Lind P, Kumnig G, Heinisch M, Igerc I, Mikosch P, Gallowitsch HJ, Kresnik E, Gomez I, Unterweger O and Aigner H, 2002. Iodine supplementation in Austria: methods and results. Thyroid, 12, 903–907.
162. Madueno Caro AJ, Cabezas Saura PB, Diaz Orta J, Benitez Rodriguez E, Ruiz Galdon M and Gomez A, 2001. [Prevalence of goitre and iodine deficiency in a school population from a traditionally endemic health area]. Atencion Primaria, 27, 258–262.
163. Maia AL, Goemann IM, Meyer EL and Wajner SM, 2011. Deiodinases: the balance of thyroid hormone: type 1 iodothyronine deiodinase in human physiology and disease. Journal of Endocrinology, 209, 283–297.
164. Malamos B, Koutras DA, Marketos SG, Rigopoulos GA, Yataganas XA, Binopoulos D, Sfontouris J, Pharmakiotis AD, Vought RL and London WT, 1967. Endemic goiter in Greece: an iodine balance study in the field. Journal of Clinical Endocrinology and Metabolism, 27, 1372–1380.
165. Malvaux P, Beckers C and De Visscher M, 1969. Iodine balance studies in nongoitrous children and in adolescents on low iodine intake. Journal of Clinical Endocrinology and Metabolism, 29, 79–84.
166. Mandel SJ, Larsen PR, Seely EW and Brent GA, 1990. Increased need for thyroxine during pregnancy in women with primary hypothyroidism. New England Journal of Medicine, 323, 91–96.
167. Mao IF, Ko YC and Chen ML, 1990. The stability of iodine in human sweat. Japanese Journal of Physiology, 40, 693–700.
168. Mao IF, Chen ML and Ko YC, 2001. Electrolyte loss in sweat and iodine deficiency in a hot environment. Archives of Environmental Health, 56, 271–277.
169. Marino C, Martinelli M, Monacelli G, Stracci F, Stalteri D, Mastrandrea V, Puxeddu E and Santeusanio F, 2006. Evaluation of goiter using ultrasound criteria: a survey in a middle schoolchildren population of a mountain area in Central Italy. Journal of Endocrinological Investigation, 29, 869–875.
170. Mattsson S and Lindstrom S, 1995. Diuresis and voiding pattern in healthy schoolchildren. British Journal of Urology, 76, 783–789.
171. Mazzarella C, Terracciano D, Di Carlo A, Macchia PE, Consiglio E, Macchia V and Mariano A, 2009. Iodine status assessment in Campania (Italy) as determined by urinary iodine excretion. Nutrition, 25, 926–929.
172. McConahey WH, Keating FR, Jr., and Power MH, 1951. An estimation of the renal and extrarenal clearance of radioiodide in man. Journal of Clinical Investigation, 30, 778–780.
173. Mendez W, Jr. and Eftim SE, 2012. Biomarkers of perchlorate exposure are correlated with circulating thyroid hormone levels in the 2007–2008 NHANES. Environmental Research, 118, 137–144.
174. Mertz W, 1987. Use and misuse of balance studies. Journal of Nutrition, 117, 1811–1813.
175. Michalke B, Schramel P and Witte H, 2000. Iodine speciation in human serum by reversed-phase liquid chromatography-ICP-mass spectrometry. Biological Trace Element Research, 78, 81–91.
176. Milakovic M, Berg G, Eggertsen R, Nystrom E, Olsson A, Larsson A and Hansson M, 2006. Determination of intrathyroidal iodine by X-ray fluorescence analysis in 60- to 65-year olds living in an iodine-sufficient area. Journal of Internal Medicine, 260, 69–75.
177. Ministère de la Santé and Direction de la Santé, 2002. Etude sur l'evaluation de la iodurie effectivée en milieu scolaire Luxembourg. Ministry of Health of Luxembourg.
178. Montenegro-Bethancourt G, Johner SA and Remer T, 2013. Contribution of fruit and vegetable intake to hydration status in schoolchildren. American Journal of Clinical Nutrition, 98, 1103–1112.
179. Moon S and Kim J, 1999. Iodine content of human milk and dietary iodine intake of Korean lactating mothers. International Journal of Food Sciences and Nutrition, 50, 165–171.
180. Morreale de Escobar G, Obregon MJ and Escobar del Rey F, 2004. Role of thyroid hormone during early brain development. European Journal of Endocrinology, 151 Suppl 3, U25–37.
181. Moulopoulos DS, Koutras DA, Mantzos J, Souvatzoglou A, Piperingos GD, Karaiskos KS, Makriyannis D, Sfontouris J and Moulopoulos SD, 1988. The relation of serum T4 and TSH with the urinary iodine excretion. Journal of Endocrinological Investigation, 11, 437–439.
182. Nath SK, Moinier B, Thuillier F, Rongier M and Desjeux JF, 1992. Urinary excretion of iodide and fluoride from supplemented food grade salt. International Journal for Vitamin and Nutrition Research, 62, 66–72.
183. Nicola JP, Basquin C, Portulano C, Reyna-Neyra A, Paroder M and Carrasco N, 2009. The Na+/I-symporter mediates active iodide uptake in the intestine. American Journal of Physiology. Cell Physiology, 296, C654–662.
184. Nicoloff JT, Low JC, Dussault JH and Fisher DA, 1972. Simultaneous measurement of thyroxine and triiodothyronine peripheral turnover kinetics in man. Journal of Clinical Investigation, 51, 473–483.
185. NNR (Nordic Nutrition Recommendations), 2004. Integrating nutrition and physical activity. Nordic Council of Ministers, Copenhagen, Denmark, 436 pp.
186. Nohr SB, Laurberg P, Borlum KG, Pedersen KM, Johannesen PL, Damm P, Fuglsang E and Johansen A, 1994. Iodine status in neonates in Denmark: regional variations and dependency on maternal iodine supplementation. Acta Paediatrica, 83, 578–582.
187. Nordic Council of Ministers, 2002. The influence of chemicals in the food and the environment on the thyroid gland function. TemaNord 2002:520, 87 pp.
188. Nordic Council of Ministers (Nordic Council of Ministers), 2014. Nordic Nutrition Recommendations 2012. Integrating nutrition and physical activity. 5th edition., 627 pp.
189. Patel J, Landers K, Li H, Mortimer RH and Richard K, 2011. Delivery of maternal thyroid hormones to the fetus. Trends in Endocrinology and Metabolism, 22, 164–170.
190. Paul T, Meyers B, Witorsch RJ, Pino S, Chipkin S, Ingbar SH and Braverman LE, 1988. The effect of small increases in dietary iodine on thyroid function in euthyroid subjects. Metabolism: Clinical and Experimental, 37, 121–124.
191. Pedersen KM, Laurberg P, Iversen E, Knudsen PR, Gregersen HE, Rasmussen OS, Larsen KR, Eriksen GM and Johannesen PL, 1993. Amelioration of some pregnancy-associated variations in thyroid function by iodine supplementation. Journal of Clinical Endocrinology and Metabolism, 77, 1078–1083.
192. Pettigrew-Porter A, Skeaff S, Gray A, Thomson C and Croxson M, 2011. Are pregnant women in New Zealand iodine deficient? A cross-sectional survey. Australian and New Zealand Journal of Obstetrics and Gynaecology, 51, 464–467.
193. Pharoah PO, Buttfield IH and Hetzel BS, 1971. Neurological damage to the fetus resulting from severe iodine deficiency during pregnancy. Lancet, 1, 308–310.
194. Phillips DI, Nelson M, Barker DJ, Morris JA and Wood TJ, 1988. Iodine in milk and the incidence of thyrotoxicosis in England. Clinical Endocrinology, 28, 61–66.
195. Phillips DI, 1997. Iodine, milk, and the elimination of endemic goitre in Britain: the story of an accidental public health triumph. Journal of Epidemiology and Community Health, 51, 391–393.
196. Queenan JT, Thompson W, Whitfield CR and Shah SI, 1972. Amniotic fluid volumes in normal pregnancies. American Journal of Obstetrics and Gynecology, 114, 34–38.
197. Rapa A, Marinello D, Chiorboli E, Sacco F and Bona G, 1999a. Iodine deficiency in Italy. Italian Study Group on Urinary Iodine of SIEDP. Lancet, 354, 596–597.
198. Rapa A, Chiorboli E, Sartorio A and Bona G, 1999b. Puberty and urinary iodine excretion. Journal of Pediatric Endocrinology and Metabolism, 12, 583–584.
199. Rasmussen LB, Ovesen L, Bulow I, Jorgensen T, Knudsen N, Laurberg P and Perrild H, 2001. Evaluation of a semi-quantitative food frequency questionnaire to estimate iodine intake. European Journal of Clinical Nutrition, 55, 287–292.
200. Rasmussen LB, Carle A, Jorgensen T, Knudsen N, Laurberg P, Pedersen IB, Perrild H, Vejbjerg P and Ovesen L, 2008. Iodine intake before and after mandatory iodization in Denmark: results from the Danish Investigation of Iodine Intake and Thyroid Diseases (DanThyr) study. British Journal of Nutrition, 100, 166–173.
201. Rayburn WF, Robinson A, Braverman LE, He XM, Pino S, Gargas ML and Kinzell JH, 2008. Iodide concentrations in matched maternal serum, cord serum, and amniotic fluid from preterm and term human pregnancies. Reproductive Toxicology, 25, 129–132.
202. Rebagliato M, Murcia M, Espada M, Alvarez-Pedrerol M, Bolumar F, Vioque J, Basterrechea M, Blarduni E, Ramon R, Guxens M, Foradada CM, Ballester F, Ibarluzea J and Sunyer J, 2010. Iodine intake and maternal thyroid function during pregnancy. Epidemiology, 21, 62–69.
203. Rebagliato M, Vioque J and Arrizabalaga JJ, 2013. Iodine supplements during and after pregnancy. JAMA, 309, 1345–1346.
204. Reinwein D, Durrer HA and Meinhold H, 1981. Iodine, thyroxine (T4), triiodothyronine (T3), 3,3′,5′-triiodothyronine (rT3), 3,3′-diiodothyronine (T2) in normal human thyroids. Effect of excessive iodine exposure. Hormone and Metabolic Research, 13, 456–459.
205. Ristić-Medić D, Piskackova Z, Hooper L, Ruprich J, Casgrain A, Ashton K, Pavlovic M and Glibetic M, 2009. Methods of assessment of iodine status in humans: a systematic review. American Journal of Clinical Nutrition, 89, 2052S–2069S.
206. Ristić-Medić D, Novaković R, Glibetić M and Gurinović M, 2013. EURRECA - Estimating iodine requirements for deriving dietary reference values. Critical Reviews in Food Science and Nutrition, 53, 1051–1063.
207. Rodondi N, den Elzen WP, Bauer DC, Cappola AR, Razvi S, Walsh JP, Asvold BO, Iervasi G, Imaizumi M, Collet TH, Bremner A, Maisonneuve P, Sgarbi JA, Khaw KT, Vanderpump MP, Newman AB, Cornuz J, Franklyn JA, Westendorp RG, Vittinghoff E, Gussekloo J and Thyroid Studies C, 2010. Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA, 304, 1365–1374.
208. Rokita SE, Adler JM, McTamney PM and Watson JA, Jr., 2010. Efficient use and recycling of the micronutrient iodide in mammals. Biochimie, 92, 1227–1235.
209. Romano R, Jannini EA, Pepe M, Grimaldi A, Olivieri M, Spennati P, Cappa F and D'Armiento M, 1991. The effects of iodoprophylaxis on thyroid size during pregnancy. American Journal of Obstetrics and Gynecology, 164, 482–485.
210. Roti E, Fang SL, Emerson CH and Braverman LE, 1981. Placental inner ring iodothyronine deiodination: a mechanism for decreased passage of T4 and T3 from mother to fetus. Transactions of the Association of American Physicians, 94, 183–189.
211. Roti E and Vagenakis G, 2000. Effect of excess iodide: clinical aspects. In: The thyroid. A fundamental and clinical text. Eds Braverman LE and Utiger RD. Lippincott Williams & Wilkins, Philadelphia, USA, 316–329.
212. Saggiorato E, Mussa A, Sacerdote C, Rossetto R, Arecco F, Origlia C, Germano L, Deandreis D, Orlandi F and Piemonte Goiter Study C, 2004. Thyroid volume and urinary iodine excretion in the schoolchild population of a Northwestern Italian sub-Alp metropolitan area. Journal of Endocrinological Investigation, 27, 516–522.
213. Saggiorato E, Arecco F, Mussa A, Sacerdote C, Rossetto R, Origlia C, Germano L, Deandreis D, Orlandi F and Piedmont Goiter Study C, 2006. Goiter prevalence and urinary iodine status in urban and rural/mountain areas of Piedmont region. Journal of Endocrinological Investigation, 29, 67–73.
214. Santiago-Fernandez P, Torres-Barahona R, Muela-Martinez JA, Rojo-Martinez G, Garcia-Fuentes E, Garriga MJ, Leon AG and Soriguer F, 2004. Intelligence quotient and iodine intake: a cross-sectional study in children. Journal of Clinical Endocrinology and Metabolism, 89, 3851–3857.
215. Santiago MI, Fernández S, Ríos M, Fluiters E, Hervada X and Iglesias YT, 2005. Excreción urinaria de yodo en escolares de Galicia. Endocrinología y Nutrición, 52, 498–505.
216. Savin S, Cvejic D, Nedic O and Radosavljevic R, 2003. Thyroid hormone synthesis and storage in the thyroid gland of human neonates. Journal of Pediatric Endocrinology and Metabolism, 16, 521–528.
217. SCF (Scientific Committee for Food), 1993. Nutrient and energy intakes for the European Community. Reports of the Scientific Committee for Food, 31st Series. Food - Science and Techniques. European Commission, Luxembourg, 248 pp.
218. SCF (Scientific Committee on Food), 2002. Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Iodine. 15 pp.
219. SCF (Scientific Committee on Food), 2003. Report of the Scientific Committee on Food on the Revision of Essential Requirements of Infant Formulae and Follow-on Formulae. 211 pp.
220. Selga G, Sauka M and Gerasimov G, 2000. Status of iodine deficiency in Latvia reconsidered: Results of a nationwide survey of school children in the year 2000. IDD Newsletter;16, 2 pp.
221. Semba RD and Delange F, 2001. Iodine in human milk: perspectives for infant health. Nutrition Reviews, 59, 269–278.
222. Serra-Prat M, Diaz E, Verde Y, Gost J, Serra E and Puig Domingo M, 2003. [Prevalence of iodine deficiency and related factors in 4 year-old schoolchildren]. Medicina Clinica, 120, 246–249.
223. Shirreffs SM and Maughan RJ, 2005. Water-electrolyte balance. In: Encyclopedia of Human Nutrition. Ed Caballero B AL, Prentice A. Elsevier, Oxford, UK, 100–105.
224. Simonsick EM, Newman AB, Ferrucci L, Satterfield S, Harris TB, Rodondi N, Bauer DC and Health ABCS, 2009. Subclinical hypothyroidism and functional mobility in older adults. Archives of Internal Medicine, 169, 2011–2017.
225. Skeaff SA, 2011. Iodine deficiency in pregnancy: the effect on neurodevelopment in the child. Nutrients, 3, 265–273.
226. Skeaff SA, 2012. Assessing iodine intakes in pregnancy and strategies for improvement. Journal of Trace Elements in Medicine and Biology, 26, 141–144.
227. Smyth P, 2002. IDD status in Ireland. Department of Medicine, University College of Dublin.
228. Smyth PP, Hetherton AM, Smith DF, Radcliff M and O'Herlihy C, 1997. Maternal iodine status and thyroid volume during pregnancy: correlation with neonatal iodine intake. Journal of Clinical Endocrinology and Metabolism, 82, 2840–2843.
229. Smyth PP, 1999. Variation in iodine handling during normal pregnancy. Thyroid, 9, 637–642.
230. Smyth PP and Duntas LH, 2005. Iodine uptake and loss - can frequent strenuous exercise induce iodine deficiency? Hormone and Metabolic Research, 37, 555–558.
231. Somwaru LL, Rariy CM, Arnold AM and Cappola AR, 2012. The natural history of subclinical hypothyroidism in the elderly: the cardiovascular health study. Journal of Clinical Endocrinology and Metabolism, 97, 1962–1969.
232. Soriguer F, Garcia-Fuentes E, Gutierrez-Repiso C, Rojo-Martinez G, Velasco I, Goday A, Bosch-Comas A, Bordiu E, Calle A, Carmena R, Casamitjana R, Castano L, Castell C, Catala M, Delgado E, Franch J, Gaztambide S, Girbes J, Gomis R, Gutierrez G, Lopez-Alba A, Martinez-Larrad MT, Menendez E, Mora-Peces I, Ortega E, Pascual-Manich G, Serrano-Rios M, Valdes S, Vazquez JA and Vendrell J, 2012. Iodine intake in the adult population. Di@bet.es study. Clinical Nutrition, 31, 882–888.
233. Spector H, Mitchell HH and Hamilton TS, 1945. The effect of environmental temperature and potassium iodide supplementation on the excretion of iodine by normal human subjects. Journal of Biological Chemistry, 161, 137–143.
234. Stanbury JB, 1960. Physiology of endemic goitre. In: Endemic goitre. Monograph Series n°44. Ed WHO. World Health Organization, Geneva, Switzerland, 261–262.
235. Stanbury JB, Ermans AM, Hetzel BS, Pretell EA and Querido A, 1974. Endemic goitre and cretinism: public health significance and prevention. WHO Chronicle, 28, 220–228.
236. Stilwell G, Reynolds PJ, Parameswaran V, Blizzard L, Greenaway TM and Burgess JR, 2008. The influence of gestational stage on urinary iodine excretion in pregnancy. Journal of Clinical Endocrinology and Metabolism, 93, 1737–1742.
237. Stockton LK and Thomas WC, 1978. Absence of neonatal goitre during maternal use of iodinated water. Clinical Research, 26, 536A.
238. Subudhi AW, Askew EW and Luetkemeier MJ, 2005. Dehydration. In: Encyclopedia of Human Nutrition. Ed Caballero B AL, Prentice A. Elsevier, Oxford, UK, 518–525.
239. Suzuki M and Tamura T, 1985. Iodine intake of Japanese male university students: urinary iodine excretion of sedentary and physically active students and sweat iodine excretion during exercise. Journal of Nutritional Science and Vitaminology, 31, 409–415.
240. Szybinski Z, 2011. Iodine nutrition in Poland. ICCIDD West-Central Europe regional meeting. Satellite to 35th annual ETA meeting. September, 2011, Krakow, Poland.
241. Teng W, Shan Z, Teng X, Guan H, Li Y, Teng D, Jin Y, Yu X, Fan C, Chong W, Yang F, Dai H, Yu Y, Li J, Chen Y, Zhao D, Shi X, Hu F, Mao J, Gu X, Yang R, Tong Y, Wang W, Gao T and Li C, 2006. Effect of iodine intake on thyroid diseases in China. New England Journal of Medicine, 354, 2783–2793.
242. Thamm M, Ellert U, Thierfelder W, Liesenkotter KP and Volzke H, 2007. [Iodine intake in Germany. Results of iodine monitoring in the German Health Interview and Examination Survey for Children and Adolescents (KiGGS)]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, 50, 744–749.
243. Thorpe-Beeston JG, Nicolaides KH, Felton CV, Butler J and McGregor AM, 1991. Maturation of the secretion of thyroid hormone and thyroid-stimulating hormone in the fetus. New England Journal of Medicine, 324, 532–536.
244. Tovar E, Maisterrena JA and Chavez A, 1969. Iodine nutrition levels of school children in rural Mexico. In: Endemic Goitre. PAHO Scientific Publication, No 193. Ed Stanbury JB. Pan American Health Organization (PAHO), Washington D. C., USA, 411–415.
245. Twyffels L, Massart C, Golstein PE, Raspe E, Van Sande J, Dumont JE, Beauwens R and Kruys V, 2011. Pendrin: the thyrocyte apical membrane iodide transporter? Cellular Physiology and Biochemistry, 28, 491–496.
246. Ubom GA, 1991. The goitre-soil-water-diet relationship: case study in Plateau State, Nigeria. Science of the Total Environment, 107, 1–11.
247. Usher R, Shephard M and Lind J, 1963. The blood volume of the newborn infant and placental transfusion. Acta Paediatrica, 52, 497–512.
248. Valsta M, Lamberg-Allardt C, Bourdoux P, Laurinen M, Kärkkäinen M, Outila T, Aro A and Pietinen P, 2003. Iodine status of middle-aged subjects in Finland. Helsinki: Finnish Society for Nutrition Research.
249. Van Buuren S, Schönbeck Y and Van Dommelen P, 2012. Collection, collation and analysis of data in relation to reference heights and reference weights for female and male children and adolescents (0–18 years) in the EU, as well as in relation to the age of onset of puberty and the age at which different stages of puberty are reached in adolescents in the EU. Project developed on the procurement project CT/EFSA/NDA/2010/01. 59 pp.
250. Van den Hove MF, Beckers C, Devlieger H, De Zegher F and De Nayer P, 1999. Hormone synthesis and storage in the thyroid of human preterm and term newborns: effect of thyroxine treatment. Biochimie, 81, 563–570.
251. Van Mil NH, Tiemeier H, Bongers-Schokking JJ, Ghassabian A, Hofman A, Hooijkaas H, Jaddoe VW, De Muinck Keizer-Schrama SM, Steegers EA, Visser TJ, Visser W, Ross HA, Verhulst FC, De Rijke YB and Steegers-Theunissen RP, 2012. Low urinary iodine excretion during early pregnancy is associated with alterations in executive functioning in children. Journal of Nutrition, 142, 2167–2174.
252. Vanderpump MP, Lazarus JH, Smyth PP, Laurberg P, Holder RL, Boelaert K, Franklyn JA and British Thyroid Association UKISG, 2011. Iodine status of UK schoolgirls: a cross-sectional survey. Lancet, 377, 2007–2012.
253. Vandevijvere S, Mourri AB, Amsalkhir S, Avni F, Van Oyen H and Moreno-Reyes R, 2012. Fortification of bread with iodized salt corrected iodine deficiency in school-aged children, but not in their mothers: a national cross-sectional survey in Belgium. Thyroid, 22, 1046–1053.
254. Veinpalu M, Ambos A, Velbri S, Vaher Y and Podar T, 1996. Urinary iodine excretion in Estonian children. European Journal of Endocrinology, 135, 248.
255. Verkaik-Kloosterman J, Van 't Veer P and Ocke MC, 2009. Simulation model accurately estimates total dietary iodine intake. Journal of Nutrition, 139, 1419–1425.
256. VMNIS (Vitamin and Mineral Nutrition Information System), online. Database on iodine deficiency. Iodine data by country. Available at: www.who.int/vmnis/database/iodine/countries/en/index.html. Accessed April 2014.
257. Vought RL and London WT, 1964. Iodine intake and excretion in healthy nonhospitalized subjects. American Journal of Clinical Nutrition, 15, 124–132.
258. Vought RL and London WT, 1965. Effect of dietary iodine on serum inorganic and salivary iodine. Metabolism: Clinical and Experimental, 14, 699–707.
259. Vought RL and London WT, 1967. Iodine intake, excretion and thyroidal accumulation in healthy subjects. Journal of Clinical Endocrinology and Metabolism, 27, 913–919.
260. Vulsma T, Gons MH and De Vijlder JJ, 1989. Maternal-fetal transfer of thyroxine in congenital hypothyroidism due to a total organification defect or thyroid agenesis. New England Journal of Medicine, 321, 13–16.
261. Wayne EJ, Koutras DA and Alexander WD, 1964. Clinical aspects of iodine metabolism. Blackwell, Oxford, UK, pp. 303.
262. WCRF/AICR (World Cancer Research Fund/American Institute for Cancer Research), 2007. Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective. 537 pp.
263. WHO (World Health Organization), 2004. Iodine status worldwide. WHO Global Database on Iodine Deficiency.
264. WHO Multicentre Growth Reference Study Group (World Health Organization), 2006. WHO Child Growth Standards: Length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: Methods and development. 312 pp.
265. WHO Secretariat, Andersson M, de Benoist B, Delange F and Zupan J, 2007. Prevention and control of iodine deficiency in pregnant and lactating women and in children less than 2-years-old: conclusions and recommendations of the Technical Consultation. Public Health Nutrition, 10, 1606–1611.
266. WHO/FAO (World Health Organization/Food and Agriculture Organization of the United Nations), 2004. Vitamin and mineral requirements in human nutrition. Joint FAO/WHO Expert Consultation on Human Vitamin and Mineral Requirements, Bangkok, Thailand 21–30 September 1998. 341 pp.
267. WHO/UNICEF (World Health Organization/United Nations Children's Fund), 2007a. Iodine deficiency in Europe. A continuing public health problem. 86 pp.
268. WHO/UNICEF (World Health Organization/ United Nations Children's Fund), 2007b. Reaching optimal iodine nutrition in pregnant and lactating women and young children. Joint statement. 2 pp.
269. WHO/UNICEF/ICCIDD (World Health Organization/United Nations Children's Fund/International Council for the Control of Iodine Deficiency Disorders), 1996. Recommended iodine levels in salt and guidelines for monitoring their adequacy and effectiveness. 13, 12 pp.
270. WHO/UNICEF/ICCIDD (World Health Organization/United Nations Children's Fund/International Council for Control of Iodine Deficiency Disorders), 2001. Assessment of the iodine deficiency disorders and monitoring their elimination. A guide for programme managers. WHO/NHD/01.1, 124 pp.
271. WHO/UNICEF/ICCIDD (World Health Organization/United Nations Children's Fund/International Council for Control of Iodine Deficiency Disorders), 2007. Assessment of iodine deficiency disorders and monitoring their elimination. A guide for programme managers. 108 pp.
272. Widdowson EM and Spray CM, 1951. Chemical development in utero. Archives of Disease in Childhood, 26, 205–214.
273. Wiersinga WM, Podoba J, Srbecky M, Van Vessem M, Van Beeren HC and Platvoet-Ter Schiphorst MC, 2001. A survey of iodine intake and thyroid volume in Dutch schoolchildren: reference values in an iodine-sufficient area and the effect of puberty. European Journal of Endocrinology, 144, 595–603.
274. Williams GR, 2008. Neurodevelopmental and neurophysiological actions of thyroid hormone. Journal of Neuroendocrinology, 20, 784–794.
275. Wu SY, Green WL, Huang WS, Hays MT and Chopra IJ, 2005. Alternate pathways of thyroid hormone metabolism. Thyroid, 15, 943–958.
276. Yassa L, Marqusee E, Fawcett R and Alexander EK, 2010. Thyroid hormone early adjustment in pregnancy (the THERAPY) trial. Journal of Clinical Endocrinology and Metabolism, 95, 3234–3241.
277. Yoshimura M and Hershman JM, 1995. Thyrotropic action of human chorionic gonadotropin. Thyroid, 5, 425–434.
278. Young VR, 1986. Nutritional balance studies: indicators of human requirements or of adaptive mechanisms? Journal of Nutrition, 116, 700–703.
279. Zamrazil V, 2011. Iodine nutrition in Czech Republic. ICCIDD West-Central Europe regional meeting. Satellite to 35th annual ETA meeting. September, 2011, Krakow, Poland.
280. Zhao J, Wang P, Shang L, Sullivan KM, Van der Haar F and Maberly G, 2000. Endemic goiter associated with high iodine intake. American Journal of Public Health, 90, 1633–1635.
281. Zhou SJ, Anderson AJ, Gibson RA and Makrides M, 2013. Effect of iodine supplementation in pregnancy on child development and other clinical outcomes: a systematic review of randomized controlled trials. American Journal of Clinical Nutrition.
282. Zimmermann MB and Delange F, 2004. Iodine supplementation of pregnant women in Europe: a review and recommendations. European Journal of Clinical Nutrition, 58, 979–984.
283. Zimmermann MB, 2007. The impact of iodised salt or iodine supplements on iodine status during pregnancy, lactation and infancy. Public Health Nutrition, 10, 1584–1595.
284. Zimmermann MB, 2009. Iodine deficiency in pregnancy and the effects of maternal iodine supplementation on the offspring: a review. American Journal of Clinical Nutrition, 89, 668S–672S.
285. Zimmermann MB and Andersson M, 2011. Prevalence of iodine deficiency in Europe in 2010. Annales d'endocrinologie, 72, 164–166.
286. Zimmermann MB, 2012. The effects of iodine deficiency in pregnancy and infancy. Paediatric and Perinatal Epidemiology, 26 Suppl 1, 108–117.
287. Zois C, Stavrou I, Kalogera C, Svarna E, Dimoliatis I, Seferiadis K and Tsatsoulis A, 2003. High prevalence of autoimmune thyroiditis in schoolchildren after elimination of iodine deficiency in northwestern Greece. Thyroid, 13, 485–489.
288. Zubiaur Cantalapiedra A, Zapico Alvarez-Cascos MD, Ruiz Perez L, Sanguino Lopez L, Sanchez Serrano FJ, Alfayate Guerra R, Sanchez-Paya J, Guirao Carratala MD, Pico Alfonso A and Flores Serrano J, 2007. [Iodine nutritional status in the school-aged population in Alicante (Spain)]. Anales de Pediatria, 66, 260–266.