Bifidobacterium dentium fortifies the intestinal mucus layer via autophagy and calcium signaling pathways

mBio

Volumn 10, Issue 3, 2019, Pages

  Engevik, Melinda A ^a,b   Luk, Berkley ^a,b   Chang Graham, Alexandra L ^a   Hall, Anne ^a,b   Herrmann, Beatrice ^a,b   Ruan, Wenly ^a,b   Endres, Bradley T ^c   Shi, Zhongcheng ^a,b   Garey, Kevin W ^c   Hyser, Joseph M ^a   Versalovic, James ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b TEXAS CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF HOUSTON   (United States)

Author keywords

Acetate; Bifidobacteria; Epithelium; GABA; Glycans; Goblet cells; Gut microbes; Intestine; Muc2; Mucins; Probiotics

Indexed keywords

4 AMINOBUTYRIC ACID; ACETIC ACID; CALCIUM; GLYCOSIDASE; GLYCOSYLTRANSFERASE; KRUPPEL LIKE FACTOR 4; MUCIN 2; TREFOIL FACTOR 3; MUC2 PROTEIN, MOUSE; MUCIN; POLYSACCHARIDE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BACTERIAL COLONIZATION; BACTERIUM ADHERENCE; BIFIDOBACTERIUM; BIFIDOBACTERIUM DENTIUM; CALCIUM SIGNALING; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; GLYCOSYLATION; GOBLET CELL; IN VITRO STUDY; IN VIVO STUDY; INTESTINAL MUCUS LAYER; KLF4 GENE; MALE; MOUSE; MUC2 GENE; MUCUS; MUCUS SECRETION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RELM BETA GENE; T84 CELL LINE; TFF3 GENE; UPREGULATION; ANIMAL; ENZYMOLOGY; GENETICS; GERMFREE ANIMAL; INTESTINE FLORA; INTESTINE MUCOSA; METABOLISM; MICROBIOLOGY; PHYSIOLOGY;

ANIMALS; AUTOPHAGY; BIFIDOBACTERIUM; CALCIUM SIGNALING; FEMALE; GASTROINTESTINAL MICROBIOME; GERM-FREE LIFE; GOBLET CELLS; HOST MICROBIAL INTERACTIONS; INTESTINAL MUCOSA; MALE; MICE; MUCIN-2; MUCINS; POLYSACCHARIDES;

EID: 85068452511     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01087-19     Document Type: Article

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