The goblet cell-derived mediator RELM-β drives spontaneous colitis in Muc2-deficient mice by promoting commensal microbial dysbiosis

Mucosal Immunology

Volumn 9, Issue 5, 2016, Pages 1218-1233

  Morampudi, V ^a   Dalwadi, U ^a   Bhinder, G ^a   Sham, H P ^a,c   Gill, S K ^b   Chan, J ^a   Bergstrom, K S B ^a,d   Huang, T ^a   Ma, C ^a   Jacobson, K ^a   Gibson, D L ^b   Vallance, B A ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LECTIN; MUCIN 2; RESISTIN; RESISTIN LIKE MOLECULE BETA; SHORT CHAIN FATTY ACID; UNCLASSIFIED DRUG; HORMONE; MUC2 PROTEIN, MOUSE; PAP PROTEIN, MOUSE; PROBIOTIC AGENT; PROTEIN; RETNLB PROTEIN, MOUSE; VOLATILE FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; COMMENSAL; CONTROLLED STUDY; DYSBIOSIS; GOBLET CELL; INTESTINE FLORA; LACTOBACILLUS; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; ULCERATIVE COLITIS; UPREGULATION; ANIMAL; BIOSYNTHESIS; COLITIS, ULCERATIVE; COLON; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INTESTINE MUCOSA; KNOCKOUT MOUSE; MICROBIOLOGY; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; SYMBIOSIS;

ANIMALS; COLITIS, ULCERATIVE; COLON; DYSBIOSIS; FATTY ACIDS, VOLATILE; GENE EXPRESSION REGULATION; GOBLET CELLS; HORMONES, ECTOPIC; INTESTINAL MUCOSA; LACTOBACILLUS; MICE; MICE, KNOCKOUT; MUCIN-2; PROBIOTICS; PROTEINS; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; SYMBIOSIS;

EID: 84982278655     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2015.140     Document Type: Article

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