The protein disulfide isomerase AGR2 is essential for production of intestinal mucus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 17, 2009, Pages 6950-6955

  Park, Sung Woo ^a,b   Zhen, Guohua ^a,c   Verhaeghe, Catherine ^a   Nakagami, Yasuhiro ^a   Nguyenvu, Louis T ^a   Barczak, Andrea J ^a   Killeen, Nigel ^a   Erle, David J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Soonchunhyang University   (South Korea)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Colitis; Endoplasmic reticulum; Goblet cell; Mucin; Protein processing

Indexed keywords

CYSTEINE; DISULFIDE; GLYCOPROTEIN; MUCIN 2; PROTEIN DERIVATIVE; PROTEIN DISULFIDE ISOMERASE AGR2; THIOREDOXIN; UNCLASSIFIED DRUG; AGR2 PROTEIN, MOUSE; MUCOPROTEIN; PROTEIN DISULFIDE ISOMERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLITIS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA; INTESTINE SECRETION; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; ACUTE DISEASE; ANIMAL; CELL LINEAGE; CHEMICALLY INDUCED DISORDER; CYTOLOGY; EPITHELIUM CELL; GENETIC PREDISPOSITION; GENETICS; INTESTINE; METABOLISM; MOUSE; MOUSE MUTANT; MUCUS; PATHOLOGY; RECTUM PROLAPSE; SECRETION;

MAMMALIA; MUS;

ACUTE DISEASE; ANIMALS; CELL LINEAGE; COLITIS; DISULFIDES; ENDOPLASMIC RETICULUM; EPITHELIAL CELLS; GENETIC PREDISPOSITION TO DISEASE; INTESTINES; MICE; MICE, KNOCKOUT; MUCIN-2; MUCOPROTEINS; MUCUS; PROTEIN DISULFIDE-ISOMERASES; RECTAL PROLAPSE; THIOREDOXINS;

EID: 66349091311     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0808722106     Document Type: Article

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