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Volumn 21, Issue 12, 2015, Pages 2737-2746

IL-33 Signaling Protects from Murine Oxazolone Colitis by Supporting Intestinal Epithelial Function

Author keywords

epithelial cells; inflammatory bowel disease; interleukin 33; oxazolone; ulcerative colitis

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; INTERLEUKIN 33; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; CYTOKINE; IL1RL1 PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR LIKE 1 PROTEIN; INTERLEUKIN RECEPTOR; OXAZOLONE;

EID: 84948124280     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0000000000000532     Document Type: Article
Times cited : (50)

References (49)
  • 1
    • 28844473957 scopus 로고    scopus 로고
    • Infliximab for induction and maintenance therapy for ulcerative colitis
    • Rutgeerts P, Sandborn WJ, Feagan BG, et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med. 2005; 353:2462-2476.
    • (2005) N Engl J Med. , vol.353 , pp. 2462-2476
    • Rutgeerts, P.1    Sandborn, W.J.2    Feagan, B.G.3
  • 2
    • 50649087272 scopus 로고    scopus 로고
    • Natural history of severe ulcerative colitis in a community-based health plan
    • Allison J, Herrinton LJ, Liu L, et al. Natural history of severe ulcerative colitis in a community-based health plan. Clin Gastroenterol Hepatol. 2008;6:999-1003.
    • (2008) Clin Gastroenterol Hepatol. , vol.6 , pp. 999-1003
    • Allison, J.1    Herrinton, L.J.2    Liu, L.3
  • 3
    • 27744446058 scopus 로고    scopus 로고
    • IL-33, an interleukin-1-like cyto-kine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
    • Schmitz J, Owyang A, Oldham E, et al. IL-33, an interleukin-1-like cyto-kine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity. 2005;23:479-490.
    • (2005) Immunity. , vol.23 , pp. 479-490
    • Schmitz, J.1    Owyang, A.2    Oldham, E.3
  • 4
    • 53249113212 scopus 로고    scopus 로고
    • The IL-33/ST2 pathway: Therapeutic target and novel biomarker
    • Kakkar R, Lee RT. The IL-33/ST2 pathway: therapeutic target and novel biomarker. Nat Rev Drug Discov. 2008;7:827-840.
    • (2008) Nat Rev Drug Discov. , vol.7 , pp. 827-840
    • Kakkar, R.1    Lee, R.T.2
  • 5
    • 84889653647 scopus 로고    scopus 로고
    • Emerging role of interleukin-33 in autoimmune diseases
    • Pei C, Barbour M, Fairlie-Clarke KJ, et al. Emerging role of interleukin-33 in autoimmune diseases. Immunology. 2014;141:9-17.
    • (2014) Immunology. , vol.141 , pp. 9-17
    • Pei, C.1    Barbour, M.2    Fairlie-Clarke, K.J.3
  • 6
    • 84859378165 scopus 로고    scopus 로고
    • Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: In situ analysis using a novel Il-33-LacZ gene trap reporter strain
    • Pichery M, Mirey E, Mercier P, et al. Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: in situ analysis using a novel Il-33-LacZ gene trap reporter strain. J Immunol. 2012;188:3488-3495.
    • (2012) J Immunol. , vol.188 , pp. 3488-3495
    • Pichery, M.1    Mirey, E.2    Mercier, P.3
  • 7
    • 84873747719 scopus 로고    scopus 로고
    • IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation
    • Hardman CS, Panova V, McKenzie ANJ. IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation. Eur J Immunol. 2012;43:488-498.
    • (2012) Eur J Immunol. , vol.43 , pp. 488-498
    • Hardman, C.S.1    Panova, V.2    McKenzie, A.N.J.3
  • 8
    • 77951817855 scopus 로고    scopus 로고
    • Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
    • Neill DR, Wong SH, Bellosi A, et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature. 2010;464: 1367-1370.
    • (2010) Nature. , vol.464 , pp. 1367-1370
    • Neill, D.R.1    Wong, S.H.2    Bellosi, A.3
  • 9
    • 75549085516 scopus 로고    scopus 로고
    • IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation
    • Kurowska-Stolarska M, Stolarski B, Kewin P, et al. IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation. J Immunol. 2009;183:6469-6477.
    • (2009) J Immunol. , vol.183 , pp. 6469-6477
    • Kurowska-Stolarska, M.1    Stolarski, B.2    Kewin, P.3
  • 10
    • 79955509396 scopus 로고    scopus 로고
    • Endogenous IL-33 enhances Th2 cyto-kine production and T-cell responses during allergic airway inflammation
    • Louten J, Rankin AL, Li Y, et al. Endogenous IL-33 enhances Th2 cyto-kine production and T-cell responses during allergic airway inflammation. Int Immunol. 2011;23:307-315.
    • (2011) Int Immunol. , vol.23 , pp. 307-315
    • Louten, J.1    Rankin, A.L.2    Li, Y.3
  • 11
    • 84455202426 scopus 로고    scopus 로고
    • Innate IL-13-producing nuo-cytes arise during allergic lung inflammation and contribute to airways hyperreactivity
    • Barlow JL, Bellosi A, Hardman CS, et al. Innate IL-13-producing nuo-cytes arise during allergic lung inflammation and contribute to airways hyperreactivity. J Allergy Clin Immunol. 2012;129:191-198.e191-194.
    • (2012) J Allergy Clin Immunol. , vol.129 , pp. 191e191-191e194
    • Barlow, J.L.1    Bellosi, A.2    Hardman, C.S.3
  • 12
    • 42149179961 scopus 로고    scopus 로고
    • IL-33, a potent inducer of adaptive immunity to intestinal nematodes
    • Humphreys NE, Xu D, Hepworth MR, et al. IL-33, a potent inducer of adaptive immunity to intestinal nematodes. J Immunol. 2008;180: 2443-2449.
    • (2008) J Immunol. , vol.180 , pp. 2443-2449
    • Humphreys, N.E.1    Xu, D.2    Hepworth, M.R.3
  • 13
    • 84872003060 scopus 로고    scopus 로고
    • IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms
    • Hung LY, Lewkowich IP, Dawson LA, et al. IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms. Proc Natl Acad Sci USA. 2013;110:282-287.
    • (2013) Proc Natl Acad Sci USA. , vol.110 , pp. 282-287
    • Hung, L.Y.1    Lewkowich, I.P.2    Dawson, L.A.3
  • 14
    • 84857640602 scopus 로고    scopus 로고
    • The alarmin interleukin-33 drives protective antiviral CD8(+) T cell responses
    • Bonilla WV, Frohlich A, Senn K, et al. The alarmin interleukin-33 drives protective antiviral CD8(+) T cell responses. Science. 2012;335:984-989.
    • (2012) Science. , vol.335 , pp. 984-989
    • Bonilla, W.V.1    Frohlich, A.2    Senn, K.3
  • 15
    • 80555126115 scopus 로고    scopus 로고
    • IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival
    • Turnquist HR, Zhao Z, Rosborough BR, et al. IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival. J Immunol. 2011;187:4598-4610.
    • (2011) J Immunol. , vol.187 , pp. 4598-4610
    • Turnquist, H.R.1    Zhao, Z.2    Rosborough, B.R.3
  • 16
    • 49449111630 scopus 로고    scopus 로고
    • IL-33 exacerbates antigen-induced arthritis by activating mast cells
    • Xu D, Jiang HR, Kewin P, et al. IL-33 exacerbates antigen-induced arthritis by activating mast cells. Proc Natl Acad Sci USA. 2008;105: 10913-10918.
    • (2008) Proc Natl Acad Sci USA. , vol.105 , pp. 10913-10918
    • Xu, D.1    Jiang, H.R.2    Kewin, P.3
  • 17
    • 77953721901 scopus 로고    scopus 로고
    • Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease
    • Beltran CJ, Nunez LE, Diaz-Jimenez D, et al. Characterization of the novel ST2/IL-33 system in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2010;16:1097-1107.
    • (2010) Inflamm Bowel Dis. , vol.16 , pp. 1097-1107
    • Beltran, C.J.1    Nunez, L.E.2    Diaz-Jimenez, D.3
  • 18
    • 78249249625 scopus 로고    scopus 로고
    • Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis
    • Kobori A, Yagi Y, Imaeda H, et al. Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis. J Gastroenterol. 2010;45:999-1007.
    • (2010) J Gastroenterol. , vol.45 , pp. 999-1007
    • Kobori, A.1    Yagi, Y.2    Imaeda, H.3
  • 19
    • 77952324145 scopus 로고    scopus 로고
    • Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis
    • Pastorelli L, Garg RR, Hoang SB, et al. Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis. Proc Natl Acad Sci USA. 2010;107:8017-8022.
    • (2010) Proc Natl Acad Sci USA. , vol.107 , pp. 8017-8022
    • Pastorelli, L.1    Garg, R.R.2    Hoang, S.B.3
  • 20
    • 74649085973 scopus 로고    scopus 로고
    • IL-33 is upregulated in colo-nocytes of ulcerative colitis
    • Seidelin JB, Bjerrum JT, Coskun M, et al. IL-33 is upregulated in colo-nocytes of ulcerative colitis. Immunol Lett. 2010;128:80-85.
    • (2010) Immunol Lett. , vol.128 , pp. 80-85
    • Seidelin, J.B.1    Bjerrum, J.T.2    Coskun, M.3
  • 21
    • 84876740406 scopus 로고    scopus 로고
    • Associations between genetic polymorphisms in IL-33 IL1R1 and risk for inflammatory bowel disease
    • Latiano A, Palmieri O, Pastorelli L, et al. Associations between genetic polymorphisms in IL-33, IL1R1 and risk for inflammatory bowel disease. PLoS One. 2013;8:e62144.
    • (2013) PLoS One. , vol.8 , pp. e62144
    • Latiano, A.1    Palmieri, O.2    Pastorelli, L.3
  • 22
    • 79960752111 scopus 로고    scopus 로고
    • Interleukin-33 suppresses Notch ligand expression and prevents goblet cell depletion in dextran sulfate sodium-induced colitis
    • Imaeda H, Andoh A, Aomatsu T, et al. Interleukin-33 suppresses Notch ligand expression and prevents goblet cell depletion in dextran sulfate sodium-induced colitis. Int J Mol Med. 2011;28:573-578.
    • (2011) Int J Mol Med. , vol.28 , pp. 573-578
    • Imaeda, H.1    Andoh, A.2    Aomatsu, T.3
  • 23
    • 84866386408 scopus 로고    scopus 로고
    • IL-33 attenuates development and perpetuation of chronic intestinal inflammation
    • Grobeta P, Doser K, Falk W, et al. IL-33 attenuates development and perpetuation of chronic intestinal inflammation. Inflamm Bowel Dis. 2012;18:1900-1909.
    • (2012) Inflamm Bowel Dis. , vol.18 , pp. 1900-1909
    • Grobeta, P.1    Doser, K.2    Falk, W.3
  • 24
    • 84870527455 scopus 로고    scopus 로고
    • Interleukin-33 ameliorates experimental colitis through promoting Th2/Foxp3(+) regulatory T-cell responses in mice
    • Duan L, Chen J, Zhang H, et al. Interleukin-33 ameliorates experimental colitis through promoting Th2/Foxp3(+) regulatory T-cell responses in mice. Mol Med. 2012;18:753-761.
    • (2012) Mol Med. , vol.18 , pp. 753-761
    • Duan, L.1    Chen, J.2    Zhang, H.3
  • 25
    • 84887459057 scopus 로고    scopus 로고
    • Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice
    • Sedhom MA, Pichery M, Murdoch JR, et al. Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice. Gut. 2013;62:1714-1723.
    • (2013) Gut. , vol.62 , pp. 1714-1723
    • Sedhom, M.A.1    Pichery, M.2    Murdoch, J.R.3
  • 26
    • 0032538915 scopus 로고    scopus 로고
    • Oxazolone colitis: A murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4
    • Boirivant M, Fuss IJ, Chu A, et al. Oxazolone colitis: a murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4. J Exp Med. 1998;188:1929-1939.
    • (1998) J Exp Med. , vol.188 , pp. 1929-1939
    • Boirivant, M.1    Fuss, I.J.2    Chu, A.3
  • 27
    • 84873537478 scopus 로고    scopus 로고
    • STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines
    • Rosen MJ, Chaturvedi R, Washington MK, et al. STAT6 deficiency ameliorates severity of oxazolone colitis by decreasing expression of claudin-2 and Th2-inducing cytokines. J Immunol. 2013;190:1849-1858.
    • (2013) J Immunol. , vol.190 , pp. 1849-1858
    • Rosen, M.J.1    Chaturvedi, R.2    Washington, M.K.3
  • 28
    • 0034689033 scopus 로고    scopus 로고
    • T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses
    • Townsend MJ, Fallon PG, Matthews DJ, et al. T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses. J Exp Med. 2000;191:1069-1076.
    • (2000) J Exp Med. , vol.191 , pp. 1069-1076
    • Townsend, M.J.1    Fallon, P.G.2    Matthews, D.J.3
  • 29
    • 78649821588 scopus 로고    scopus 로고
    • IL-33 is a crucial amplifier of innate rather than acquired immunity
    • Oboki K, Ohno T, Kajiwara N, et al. IL-33 is a crucial amplifier of innate rather than acquired immunity. Proc Natl Acad Sci USA. 2010;107:18581-18586.
    • (2010) Proc Natl Acad Sci USA. , vol.107 , pp. 18581-18586
    • Oboki, K.1    Ohno, T.2    Kajiwara, N.3
  • 30
    • 0033772055 scopus 로고    scopus 로고
    • Interleukin 10-deficient colitis: New similarities to human inflammatory bowel disease
    • Kennedy RJ, Hoper M, Deodhar K, et al. Interleukin 10-deficient colitis: new similarities to human inflammatory bowel disease. Br J Surg. 2000; 87:1346-1351.
    • (2000) Br J Surg. , vol.87 , pp. 1346-1351
    • Kennedy, R.J.1    Hoper, M.2    Deodhar, K.3
  • 31
    • 42249098670 scopus 로고    scopus 로고
    • IL-9-and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity
    • Forbes EE, Groschwitz K, Abonia JP, et al. IL-9-and mast cell-mediated intestinal permeability predisposes to oral antigen hypersensitivity. J Exp Med. 2008;205:897-913.
    • (2008) J Exp Med. , vol.205 , pp. 897-913
    • Forbes, E.E.1    Groschwitz, K.2    Abonia, J.P.3
  • 32
    • 0032958705 scopus 로고    scopus 로고
    • Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis
    • Schmitz H, Barmeyer C, Fromm M, et al. Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis. Gastroenterology. 1999;116:301-309.
    • (1999) Gastroenterology. , vol.116 , pp. 301-309
    • Schmitz, H.1    Barmeyer, C.2    Fromm, M.3
  • 33
    • 84906571227 scopus 로고    scopus 로고
    • The alarmin IL-33 promotes regulatory T-cell function in the intestine
    • Schiering C, Krausgruber T, Chomka A, et al. The alarmin IL-33 promotes regulatory T-cell function in the intestine. Nature. 2014;513:564-568.
    • (2014) Nature. , vol.513 , pp. 564-568
    • Schiering, C.1    Krausgruber, T.2    Chomka, A.3
  • 34
    • 0036850908 scopus 로고    scopus 로고
    • Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells
    • Heller F, Fuss IJ, Nieuwenhuis EE, et al. Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells. Immunity. 2002;17:629-638.
    • (2002) Immunity. , vol.17 , pp. 629-638
    • Heller, F.1    Fuss, I.J.2    Nieuwenhuis, E.E.3
  • 35
    • 10744222880 scopus 로고    scopus 로고
    • Specific regulation of T helper cell 1-mediated murine colitis by CEACAM1
    • Iijima H, Neurath MF, Nagaishi T, et al. Specific regulation of T helper cell 1-mediated murine colitis by CEACAM1. J Exp Med. 2004;199:471-482.
    • (2004) J Exp Med. , vol.199 , pp. 471-482
    • Iijima, H.1    Neurath, M.F.2    Nagaishi, T.3
  • 36
    • 84903783722 scopus 로고    scopus 로고
    • Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation
    • Li J, Razumilava N, Gores GJ, et al. Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation. J Clin Invest. 2014;124:3241-3251.
    • (2014) J Clin Invest. , vol.124 , pp. 3241-3251
    • Li, J.1    Razumilava, N.2    Gores, G.J.3
  • 37
    • 84935926011 scopus 로고    scopus 로고
    • IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis
    • Seidelin JB, Coskun M, Kvist PH, et al. IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis. J Gastroenterol. 2015;50:180-190.
    • (2015) J Gastroenterol. , vol.50 , pp. 180-190
    • Seidelin, J.B.1    Coskun, M.2    Kvist, P.H.3
  • 38
    • 44849117539 scopus 로고    scopus 로고
    • Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
    • Kondo Y, Yoshimoto T, Yasuda K, et al. Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system. Int Immunol. 2008;20:791-800.
    • (2008) Int Immunol. , vol.20 , pp. 791-800
    • Kondo, Y.1    Yoshimoto, T.2    Yasuda, K.3
  • 39
    • 84904241397 scopus 로고    scopus 로고
    • Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy
    • McSorley HJ, Blair NF, Smith KA, et al. Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy. Mucosal Immunol. 2014;7:1068-1078.
    • (2014) Mucosal Immunol. , vol.7 , pp. 1068-1078
    • McSorley, H.J.1    Blair, N.F.2    Smith, K.A.3
  • 40
    • 0033570791 scopus 로고    scopus 로고
    • The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function
    • Hoshino K, Kashiwamura S, Kuribayashi K, et al. The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function. J Exp Med. 1999;190:1541-1548.
    • (1999) J Exp Med. , vol.190 , pp. 1541-1548
    • Hoshino, K.1    Kashiwamura, S.2    Kuribayashi, K.3
  • 41
    • 39849109700 scopus 로고    scopus 로고
    • Crosstalk of tight junction components with signaling pathways
    • Gonzalez-Mariscal L, Tapia R, Chamorro D. Crosstalk of tight junction components with signaling pathways. Biochim Biophys Acta. 2008;1778:729-756.
    • (2008) Biochim Biophys Acta. , vol.1778 , pp. 729-756
    • Gonzalez-Mariscal, L.1    Tapia, R.2    Chamorro, D.3
  • 42
    • 19944428359 scopus 로고    scopus 로고
    • Transforming growth factor beta-1 and gene polymorphisms in oriental ankylosing spondylitis
    • Howe HS, Cheung PL, Kong KO, et al. Transforming growth factor beta-1 and gene polymorphisms in oriental ankylosing spondylitis. Rheumatology (Oxford). 2005;44:51-54.
    • (2005) Rheumatology (Oxford). , vol.44 , pp. 51-54
    • Howe, H.S.1    Cheung, P.L.2    Kong, K.O.3
  • 43
    • 84855162180 scopus 로고    scopus 로고
    • VSL#3 probiotics regulate the intestinal epithelial barrier in vivo and in vitro via the p38 and ERK signaling pathways
    • Dai C, Zhao DH, Jiang M. VSL#3 probiotics regulate the intestinal epithelial barrier in vivo and in vitro via the p38 and ERK signaling pathways. Int JMol Med. 2012;29:202-208.
    • (2012) Int JMol Med. , vol.29 , pp. 202-208
    • Dai, C.1    Zhao, D.H.2    Jiang, M.3
  • 44
    • 84874052457 scopus 로고    scopus 로고
    • IL-33-induced alterations in murine intestinal function and cytokine responses are MyD88, STAT6, and IL-13 dependent
    • Yang Z, Sun R, Grinchuk V, et al. IL-33-induced alterations in murine intestinal function and cytokine responses are MyD88, STAT6, and IL-13 dependent. Am J Physiol Gastrointest Liver Physiol. 2013;304:G381-G389.
    • (2013) Am J Physiol Gastrointest Liver Physiol. , vol.304 , pp. G381-G389
    • Yang, Z.1    Sun, R.2    Grinchuk, V.3
  • 45
    • 23244455992 scopus 로고    scopus 로고
    • Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution
    • Heller F, Florian P, Bojarski C, et al. Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution. Gastroenterology. 2005;129:550-564.
    • (2005) Gastroenterology. , vol.129 , pp. 550-564
    • Heller, F.1    Florian, P.2    Bojarski, C.3
  • 46
    • 0021379895 scopus 로고
    • A human colonic tumor cell line that maintains vectorial electrolyte transport
    • Dharmsathaphorn K, McRoberts JA, Mandel KG, et al. A human colonic tumor cell line that maintains vectorial electrolyte transport. Am J Physiol 1984;246:G204-G208.
    • (1984) Am J Physiol , vol.246 , pp. G204-G208
    • Dharmsathaphorn, K.1    McRoberts, J.A.2    Mandel, K.G.3
  • 47
    • 53749093767 scopus 로고    scopus 로고
    • The IL-1-like cytokine IL-33 is con-stitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: A novel "alarmin"?
    • Moussion C, Ortega N, Girard JP. The IL-1-like cytokine IL-33 is con-stitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel "alarmin"? PLoS One. 2008;3:e3331.
    • (2008) PLoS One. , vol.3 , pp. e3331
    • Moussion, C.1    Ortega, N.2    Girard, J.P.3
  • 48
    • 84922404569 scopus 로고    scopus 로고
    • Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation
    • Bessa J, Meyer CA, de Vera Mudry MC, et al. Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation. JAutoimmun. 2014;55:33-41.
    • (2014) JAutoimmun. , vol.55 , pp. 33-41
    • Bessa, J.1    Meyer, C.A.2    De Vera Mudry, M.C.3
  • 49
    • 84899106298 scopus 로고    scopus 로고
    • IL-10-producing regulatory B cells induced by IL-33 (Breg(IL-33)) effectively attenuate mucosal inflammatory responses in the gut
    • Sattler S, Ling GS, Xu D, et al. IL-10-producing regulatory B cells induced by IL-33 (Breg(IL-33)) effectively attenuate mucosal inflammatory responses in the gut. J Autoimmun. 2014;50:107-122.
    • (2014) J Autoimmun. , vol.50 , pp. 107-122
    • Sattler, S.1    Ling, G.S.2    Xu, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.