IL-13 induces the expression of the alternative activation marker Ym1 in a subset of testicular macrophages

Journal of Reproductive Immunology

Volumn 78, Issue 2, 2008, Pages 140-148

  Maresz, Katarzyna ^a   Ponomarev, Eugene D ^a   Barteneva, Natasha ^b   Tan, Yanping ^a   Mann, Monica K ^a,c   Dittel, Bonnie N ^a,c  

^a BLOOD RESEARCH INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Immune privilege; Immunosuppressive; Lung; Testis; Th2 immunity

Indexed keywords

CD11B ANTIGEN; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR; INTERLEUKIN 14; MARKER; PROTEIN; YM1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL POPULATION; CYTOKINE PRODUCTION; IMMUNITY; MACROPHAGE; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TESTIS;

ANIMALS; BETA-N-ACETYLHEXOSAMINIDASES; INTERLEUKIN-13; INTERLEUKIN-4; LECTINS; LIVER; LUNG; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; RECEPTORS, INTERLEUKIN-13; TESTIS;

EID: 46549084100     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2008.01.001     Document Type: Article

References (34)

1. Arora M., Chen L., Paglia M., Gallagher I., Allen J.E., Vyas Y.M., Ray A., and Ray P. Simvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 7777-7782
2. Bryniarski K., Szczepanik M., Maresz K., Ptak M., and Ptak W. Subpopulations of mouse testicular macrophages and their immunoregulatory function. Am. J. Reprod. Immunol. 52 (2004) 27-35
3. Bryniarski K., Szczepanik M., Ptak M., and Ptak W. The influence of collagenase treatment on the production of TNF-α, IL-6 and IL-10 by testicular macrophages. J. Immunol. Methods 301 (2005) 186-189
4. Chang N.C., Hung S.I., Hwa K.Y., Kato I., Chen J.E., Liu C.H., and Chang A.C. A macrophage protein, Ym1, transiently expressed during inflammation is a novel mammalian lectin. J. Biol. Chem. 276 (2001) 17497-17506
5. Debinski W., and Gibo D.M. Molecular expression analysis of restrictive receptor for interleukin 13, a brain tumor-associated cancer/testis antigen. Mol. Med. 6 (2000) 440-449
6. Dittel B.N., Sant'Angelo D.B., and Janeway Jr. C.A. Peptide antagonists inhibit proliferation and the production of IL-4 and/or IFN-γ in T helper 1, T helper 2, and T helper 0 clones bearing the same TCR. J. Immunol. 158 (1997) 4065-4073
7. Doherty T.M., Kastelein R., Menon S., Andrade S., and Coffman R.L. Modulation of murine macrophage function by IL-13. J. Immunol. 151 (1993) 7151-7160
8. Edwards J.P., Zhang X., Frauwirth K.A., and Mosser D.M. Biochemical and functional characterization of three activated macrophage populations. J. Leukoc. Biol. 80 (2006) 1298-1307
9. Fijak M., and Meinhardt A. The testis in immune privilege. Immunol. Rev. 213 (2006) 66-81
10. Galli S.J., Nakae S., and Tsai M. Mast cells in the development of adaptive immune responses. Nat. Immunol. 6 (2005) 135-142
11. Gordon S. Alternative activation of macrophages. Nat. Rev. Immunol. 3 (2003) 23-35
12. Guo L., Johnson R.S., and Schuh J.C. Biochemical characterization of endogenously formed eosinophilic crystals in the lungs of mice. J. Biol. Chem. 275 (2000) 8032-8037
13. Hilton D.J., Zhang J.G., Metcalf D., Alexander W.S., Nicola N.A., and Willson T.A. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 497-501
14. Hutson J.C., and Stocco D.M. Comparison of cellular and secreted proteins of macrophages from the testis and peritoneum on two-dimensional polyacrylamide gels: evidence of tissue specific function. Reg. Immunol. 2 (1989) 249-253
15. Jin H.M., Copeland N.G., Gilbert D.J., Jenkins N.A., Kirkpatrick R.B., and Rosenberg M. Genetic characterization of the murine Ym1 gene and identification of a cluster of highly homologous genes. Genomics 54 (1998) 316-322
16. Kodelja V., Muller C., Tenorio S., Schebesch C., Orfanos C.E., and Goerdt S. Differences in angiogenic potential of classically vs alternatively activated macrophages. Immunobiology 197 (1997) 478-493
17. 1. J. Exp. Med. 194 (2001) 809-821
18. McKenzie G.J., Fallon P.G., Emson C.L., Grencis R.K., and McKenzie A.N. Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses. J. Exp. Med. 189 (1999) 1565-1572
19. Mentink-Kane M.M., and Wynn T.A. Opposing roles for IL-13 and IL-13 receptor α2 in health and disease. Immunol. Rev. 202 (2004) 191-202
20. Moore W.C., and Peters S.P. Severe asthma: an overview. J. Allergy Clin. Immunol. 117 (2006) 487-494
21. Mosser D.M. The many faces of macrophage activation. J. Leukoc. Biol. 73 (2003) 209-212
22. Munder M., Eichmann K., Moran J.M., Centeno F., Soler G., and Modolell M. Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells. J. Immunol. 163 (1999) 3771-3777
23. Naz R.K. Modalities for treatment of antisperm antibody mediated infertility: novel perspectives. Am. J. Reprod. Immunol. 51 (2004) 390-397
24. Nes W.D., Lukyanenko Y.O., Jia Z.H., Quideau S., Howald W.N., Pratum T.K., West R.R., and Hutson J.C. Identification of the lipophilic factor produced by macrophages that stimulates steroidogenesis. Endocrinology 141 (2000) 953-958
25. Nio J., Fujimoto W., Konno A., Kon Y., Owhashi M., and Iwanaga T. Cellular expression of murine Ym1 and Ym2, chitinase family proteins, as revealed by in situ hybridization and immunohistochemistry. Histochem. Cell Biol. 121 (2004) 473-482
26. Overbergh L., Valckx D., Waer M., and Mathieu C. Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR. Cytokine 11 (1999) 305-312
27. Ponomarev E.D., Shriver L.P., Maresz K., and Dittel B.N. Microglial cell activation and proliferation precedes the onset of CNS autoimmunity. J. Neurosci. Res. 81 (2005) 374-389
28. Raes G., Brys L., Dahal B.K., Brandt J., Grooten J., Brombacher F., Vanham G., Noel W., Bogaert P., Boonefaes T., Kindt A., Van den Bergh R., Leenen P.J., De Baetselier P., and Ghassabeh G.H. Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation. J. Leukoc. Biol. 77 (2005) 321-327
29. Raes G., De Baetselier P., Noel W., Beschin A., Brombacher F., and Hassanzadeh G. Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages. J. Leukoc. Biol. 71 (2002) 597-602
30. Song E., Ouyang N., Horbelt M., Antus B., Wang M., and Exton M.S. Influence of alternatively and classically activated macrophages on fibrogenic activities of human fibroblasts. Cell. Immunol. 204 (2000) 19-28
31. Stein M., Keshav S., Harris N., and Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp. Med. 176 (1992) 287-292
32. Tsai M.L., Liaw S.H., and Chang N.C. The crystal structure of Ym1 at 1.31 Å resolution. J. Struct. Biol. 148 (2004) 290-296
33. Ward J.M., Yoon M., Anver M.R., Haines D.C., Kudo G., Gonzalez F.J., and Kimura S. Hyalinosis and Ym1/Ym2 gene expression in the stomach and respiratory tract of 129S4/SvJae and wild-type and CYP1A2-null B6, 129 mice. Am. J. Pathol. 158 (2001) 323-332
34. Welch J.S., Escoubet-Lozach L., Sykes D.B., Liddiard K., Greaves D.R., and Glass C.K. TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism. J. Biol. Chem. 277 (2002) 42821-42829