Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification

Neuron

Volumn 102, Issue 6, 2019, Pages 1111-1126.e5

  Clark, Brian S ^a   Stein O'Brien, Genevieve L ^a,b   Shiau, Fion ^a   Cannon, Gabrielle H ^a   Davis Marcisak, Emily ^a,b   Sherman, Thomas ^b   Santiago, Clayton P ^a   Hoang, Thanh V ^a   Rajaii, Fatemeh ^a   James Esposito, Rebecca E ^a   Gronostajski, Richard M ^d   Fertig, Elana J ^a,b,c   Goff, Loyal A ^a,c   Blackshaw, Seth ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c Johns Hopkins University   (United States)

^d UNIVERSITY AT BUFFALO   (United States)

Author keywords

cell fate; CoGAPS; development; M ller glia; neural progenitor; neurogenesis; photoreceptor; proliferation; retina; scRNA seq; single cell RNA sequencing

Indexed keywords

TRANSCRIPTION FACTOR; NFIA PROTEIN, MOUSE; NFIB PROTEIN, MOUSE; NFIX PROTEIN, MOUSE; NUCLEAR FACTOR I;

ADULT; ANIMAL CELL; ARTICLE; CELL FATE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; FEMALE; GENE EXPRESSION; GENE IDENTIFICATION; INTERNEURON; MALE; MITOSIS; MOUSE; MUELLER CELL; NERVOUS SYSTEM DEVELOPMENT; NFIA GENE; NFIB GENE; NFIX GENE; NONHUMAN; PRIORITY JOURNAL; RETINA CELL; RETINA DEVELOPMENT; RNA SEQUENCE; SINGLE CELL ANALYSIS; STEM CELL; ANIMAL; CELL PROLIFERATION; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; MACROGLIA; METABOLISM; NEURAL STEM CELL; RETINA; RETINA NERVE CELL;

ANIMALS; CELL PROLIFERATION; EPENDYMOGLIAL CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTERNEURONS; MICE; MITOSIS; NEURAL STEM CELLS; NEUROGENESIS; NFI TRANSCRIPTION FACTORS; RETINA; RETINAL NEURONS; RNA-SEQ; SINGLE-CELL ANALYSIS;

EID: 85065608375     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2019.04.010     Document Type: Article

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