AAV-Mediated, Optogenetic Ablation of Müller Glia Leads to Structural and Functional Changes in the Mouse Retina

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Byrne, Leah C ^a   Khalid, Fakhra ^a   Lee, Trevor ^a   Zin, Emilia A ^a   Greenberg, Kenneth P ^b   Visel, Meike ^a   Schaffer, David V ^c   Flannery, John G ^a  

^a University of California Berkeley   (United States)

^b Spiral Devices LLC   (United States)

^c University of California   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE AMMONIA LIGASE; OPSIN; RETINOID BINDING PROTEIN; RHODOPSIN;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ELECTRORETINOGRAM; FUNCTIONAL MORPHOLOGY; MOUSE; MUELLER CELL; NONHUMAN; OPTOGENETICS; PHAGOCYTE; PHOTORECEPTOR INNER SEGMENT; PHOTORECEPTOR OUTER SEGMENT; PROTEIN EXPRESSION; RETINA BLOOD VESSEL; RETINA DEGENERATION; RETINAL THICKNESS; UPREGULATION;

ABLATION TECHNIQUES; ANIMALS; CARRIER PROTEINS; DEPENDOVIRUS; ELECTRORETINOGRAPHY; EPENDYMOGLIAL CELLS; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE-AMMONIA LIGASE; GREEN FLUORESCENT PROTEINS; INTRAVITREAL INJECTIONS; MICE; OPSINS; OPTOGENETICS; RETINA;

EID: 84884692956     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076075     Document Type: Article

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