Maternal prebiotic supplementation reduces fatty liver development in offspring through altered microbial and metabolomic profiles in rats

FASEB Journal

Volumn 33, Issue 4, 2019, Pages 5153-5167

  Paul, Heather A ^a   Collins, Kelsey H ^c   Nicolucci, Alissa C ^c   Urbanski, Stefan J ^a   Hart, David A ^b,c   Vogel, Hans J ^a,c   Reimer, Raylene A ^a,c  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

Author keywords

Gut microbiota; Insulin sensitivity; Oligofructose; Pregnancy; Steatosis

Indexed keywords

EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; FAT; FRUCTOSE OLIGOSACCHARIDE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOSE; GRANULOCYTE COLONY STIMULATING FACTOR; INSULIN; INTERLEUKIN 13; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; ORAFTI P 95; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PREBIOTIC AGENT; SUCROSE; TRIACYLGLYCEROL; OLIGOSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIET INDUCED OBESITY; FEMALE; GENE EXPRESSION PROFILING; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HIGH FAT/HIGH SUCROSE DIET; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTESTINE FLORA; LIVER TISSUE; MALE; MATERNAL CARE; MATERNAL NUTRITION; MATERNAL OBESITY; METABOLOMICS; NONALCOHOLIC FATTY LIVER; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; POST HOC ANALYSIS; PRIORITY JOURNAL; PROGENY; RAT; SUPPLEMENTATION; TRIACYLGLYCEROL BLOOD LEVEL; WEANING; ADVERSE EVENT; ANIMAL; BODY WEIGHT GAIN; FATTY LIVER; GLUCOSE TOLERANCE TEST; LIPID DIET; METABOLISM; MICROBIOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT;

ANIMALS; DIET, HIGH-FAT; FATTY LIVER; FEMALE; GASTROINTESTINAL MICROBIOME; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; MAGNETIC RESONANCE SPECTROSCOPY; METABOLOMICS; OLIGOSACCHARIDES; PREBIOTICS; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; SUCROSE; TRIGLYCERIDES; WEIGHT GAIN;

EID: 85064117674     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.201801551R     Document Type: Article

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