Establishment of a general NAFLD scoring system for rodent models and comparison to human liver pathology

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Liang, Wen ^a,b   Menke, Aswin L ^c   Driessen, Ann ^d   Koek, Ger H ^e   Lindeman, Jan H ^b   Stoop, Reinout ^a   Havekes, Louis M ^a,b   Kleemann , Robert ^a   Van Den Hoek, Anita M ^a  

^a Department of Metabolic Health Research ^*  (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c TNO   (Netherlands)

^d ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^e MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEPATITIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HUMAN VERSUS ANIMAL COMPARISON; LIVER BIOPSY; LIVER FIBROSIS; LIVER HYPERTROPHY; MACROVESICULAR STEATOSIS; MALE; MICROVESICULAR STEATOSIS; NONALCOHOLIC FATTY LIVER; NONHUMAN; PROCESS DEVELOPMENT; REPRODUCIBILITY; SCORING SYSTEM; STEATOSIS; VALIDATION PROCESS; ANIMAL; C57BL MOUSE; COMPARATIVE STUDY; DISEASE MODEL; HEPATOMEGALY; HISTOLOGY; INFLAMMATION; LIVER; MOUSE; PATHOLOGY; SEVERITY OF ILLNESS INDEX;

RODENTIA;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; HEPATOMEGALY; HISTOLOGICAL TECHNIQUES; HUMANS; INFLAMMATION; LIVER; MALE; MICE; MICE, INBRED C57BL; NON-ALCOHOLIC FATTY LIVER DISEASE; REPRODUCIBILITY OF RESULTS; SEVERITY OF ILLNESS INDEX;

EID: 84919800427     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115922     Document Type: Article

References (28)

1. Lazo M, Clark JM (2008) The epidemiology of nonalcoholic fatty liver disease: A global perspective. Semin Liver Dis 28: 339-350.
2. Williams CD, Stengel J, Asike MI, Torres DM, Shaw J, et al. (2011) Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: A prospective study. Gastroenterology 140: 124-131.
3. Tiniakos DG, Vos MB, Brunt EM (2010) Nonalcoholic fatty liver disease: Pathology and pathogenesis. Annu Rev Pathol 5: 145-171.
4. Younossi ZM (2008) Review article: Current management of non-alcoholic fatty liver disease and nonalcoholic steatohepatitis. Aliment Pharmacol Ther 28: 2-12.
5. Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, et al. (2005) Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 41: 1313-1321.
6. Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR (1999) Nonalcoholic steatohepatitis: A proposal for grading and staging the histological lesions. Am J Gastroenterol 94: 2467-2474.
7. van den Maagdenberg AM, Hofker MH, Krimpenfort PJ, de Bruijn I, van Vlijmen B, et al. (1993) Transgenic mice carrying the apolipoprotein E3-leiden gene exhibit hyperlipoproteinemia. J Biol Chem 268: 10540-10545.
8. Nishina PM, Verstuyft J, Paigen B (1990) Synthetic low and high fat diets for the study of atherosclerosis in the mouse. J Lipid Res 31: 859-869.
9. Jiang XC, Agellon LB, Walsh A, Breslow JL, Tall A (1992) Dietary cholesterol increases transcription of the human cholesteryl ester transfer protein gene in transgenic mice. dependence on natural flanking sequences. J Clin Invest 90: 1290-1295.
10. van den Hoek AM, van der Hoorn JW, Maas AC, van den Hoogen RM, van Nieuwkoop A, et al. (2014) APOE∗3Leiden.CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome. Diabetes Obes Metab 16: 537-544.
11. Westerterp M, van der Hoogt CC, de Haan W, Offerman EH, Dallinga-Thie GM, et al. (2006) Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE∗3-leiden mice. Arterioscler Thromb Vasc Biol 26: 2552-2559.
12. Verschuren L, Kooistra T, Bernhagen J, Voshol PJ, Ouwens DM, et al. (2009) MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease. Circ Res 105: 99-107.
13. Munro B (1997) Statistical methods for health care research. New York: Lippincott Williams & Willkins.
14. Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1: 307-310.
15. Brunt EM (2010) Pathology of nonalcoholic fatty liver disease. Nat Rev Gastroenterol Hepatol 7: 195- 203.
16. Brunt EM (2001) Nonalcoholic steatohepatitis: Definition and pathology. Semin Liver Dis 21: 3-16.
17. Bedossa P, Poitou C, Veyrie N, Bouillot JL, Basdevant A, et al. (2012) Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients. Hepatology 56: 1751-1759.
18. Lackner C (2011) Hepatocellular ballooning in nonalcoholic steatohepatitis: The pathologist's perspective. Expert Rev Gastroenterol Hepatol 5: 223-231.
19. Caldwell S, Ikura Y, Dias D, Isomoto K, Yabu A, et al. (2010) Hepatocellular ballooning in NASH. J Hepatol 53: 719-723.
20. Liang W, Lindeman JH, Menke AL, Koonen DP, Morrison M, et al. (2014) Metabolically induced liver inflammation leads to NASH and differs from LPS- or IL-1beta-induced chronic inflammation. Lab Invest 94: 491-502.
21. Kleiner DE, Brunt EM (2012) Nonalcoholic fatty liver disease: Pathologic patterns and biopsy evaluation in clinical research. Semin Liver Dis 32: 3-13.
22. Ratziu V, Charlotte F, Heurtier A, Gombert S, Giral P, et al. (2005) Sampling variability of liver biopsy in nonalcoholic fatty liver disease. Gastroenterology 128: 1898-1906.
23. Goldstein NS, Hastah F, Galan MV, Gordon SC (2005) Fibrosis heterogeneity in nonalcoholic steatohepatitis and hepatitis C virus needle core biopsy specimens. Am J Clin Pathol 123: 382-387.
24. Younossi ZM, Gramlich T, Liu YC, Matteoni C, Petrelli M, et al. (1998) Nonalcoholic fatty liver disease: Assessment of variability in pathologic interpretations. Mod Pathol 11: 560-565.
25. Fukusato T, Fukushima J, Shiga J, Takahashi Y, Nakano T, et al. (2005) Interobserver variation in the histopathological assessment of nonalcoholic steatohepatitis. Hepatol Res 33: 122-127.
26. Merriman RB, Ferrell LD, Patti MG, Weston SR, Pabst MS, et al. (2006) Correlation of paired liver biopsies in morbidly obese patients with suspected nonalcoholic fatty liver disease. Hepatology 44: 874- 880.
27. Vuppalanchi R, Unalp A, Van Natta ML, Cummings OW, Sandrasegaran KE, et al. (2009) Effects of liver biopsy sample length and number of readings on sampling variability in nonalcoholic fatty liver disease. Clin Gastroenterol Hepatol 7: 481-486.
28. Juluri R, Vuppalanchi R, Olson J, Unalp A, Van Natta ML, et al. (2011) Generalizability of the nonalcoholic steatohepatitis clinical research network histologic scoring system for nonalcoholic fatty liver disease. J Clin Gastroenterol 45: 55-58.