The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages

Immunity

Volumn 48, Issue 1, 2018, Pages 35-44.e6

  Evavold, Charles L ^a,b   Ruan, Jianbin ^a   Tan, Yunhao ^a   Xia, Shiyu ^a   Wu, Hao ^a   Kagan, Jonathan C ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; CASPASE 11; GASDERMIN D; INFLAMMASOME; INTERLEUKIN 1; INTERLEUKIN 18; LIPOSOME; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; GSDMD PROTEIN, HUMAN; INTERLEUKIN 1BETA; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CELL DIFFERENTIATION; CELL MEMBRANE; CHANNEL GATING; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; EXTRACELLULAR SPACE; FLOW CYTOMETRY; LIPID BILAYER; MACROPHAGE; MEMBRANE RUPTURE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PHAGOCYTOSIS; PROTEIN EXPRESSION; PYROPTOSIS; STAPHYLOCOCCUS AUREUS; ANIMAL; CELL LINE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT;

ANIMALS; CELL LINE; CELL MEMBRANE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; MACROPHAGES; NEOPLASM PROTEINS; PROTEIN TRANSPORT; PYROPTOSIS;

EID: 85061560626     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.11.013     Document Type: Article

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