A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection

Cell Reports

Volumn 16, Issue 2, 2016, Pages 571-582

  Tzeng, Te Chen ^a   Schattgen, Stefan ^a   Monks, Brian ^a,b   Wang, Donghai ^a   Cerny, Anna ^a   Latz, Eicke ^a,b   Fitzgerald, Katherine ^a   Golenbock, Douglas T ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN CONTAINING A CASPASE RECRUITMENT DOMAIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; UNCLASSIFIED DRUG; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; PYCARD PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL POPULATION; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; GROUP B STREPTOCOCCAL INFECTION; HEMATOPOIETIC CELL; INFLUENZA A VIRUS; MOUSE; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PYROPTOSIS; STREPTOCOCCUS INFECTION; STROMA CELL; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; GENE EXPRESSION; GENETICS; IMMUNOLOGY; MALE; METABOLISM; ORTHOMYXOVIRUS INFECTION; PROTEIN MULTIMERIZATION; REPORTER GENE; TRANSGENIC MOUSE;

ANIMALS; CARD SIGNALING ADAPTOR PROTEINS; FEMALE; GENE EXPRESSION; GENES, REPORTER; INFLAMMASOMES; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; ORTHOMYXOVIRIDAE INFECTIONS; PERITONITIS; PROTEIN MULTIMERIZATION; STREPTOCOCCAL INFECTIONS;

EID: 84992512820     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.06.011     Document Type: Article

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